XO Cancer Research Results

XO, xanthine oxidase: Click to Expand ⟱
Source:
Type:
xanthine oxidase The relationship between XO (xanthine oxidase) and Alzheimer’s disease (AD) is an emerging topic in neurodegenerative research, mainly because of XO's role in oxidative stress and inflammation, which are both key features in AD pathology.
-Studies suggest oxidative stress from XO may increase Aβ aggregation and promote tau phosphorylation, both critical to AD progression.
Scientific Papers found: Click to Expand⟱
3713- FA,    Protective Effect of Ferulic Acid on Acetylcholinesterase and Amyloid Beta Peptide Plaque Formation in Alzheimer’s Disease: An In Vitro Study
- Review, AD, NA
*AChE↓, FA has the potential to be an AChE inhibitor, thus helping in blocking the activity of AChE and also reducing the incidence of amyloid beta plaque formation.
*antiOx↑, significant antioxidant property
*neuroP↑, FA has significant antioxidant and neuroprotective effects
*Aβ↓,
*MMP↓, restore mitochondrial membrane potential
*XO↓, FA, at concentrations ranging from 10 Inline graphicM to 320 Inline graphicM, demonstrated substantial inhibition of XO,
*SOD↑, FA has demonstrated the restoration of SOD activity, mitigated lipid peroxidation, and exhibited free radical scavenging capabilities
*lipid-P↑,
*ROS↓,


Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 1,   lipid-P↑, 1,   ROS↓, 1,   SOD↑, 1,  

Mitochondria & Bioenergetics ⓘ

MMP↓, 1,  

Synaptic & Neurotransmission ⓘ

AChE↓, 1,  

Protein Aggregation ⓘ

Aβ↓, 1,   XO↓, 1,  

Functional Outcomes ⓘ

neuroP↑, 1,  
Total Targets: 9

Scientific Paper Hit Count for: XO, xanthine oxidase
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1353  State#:%  Dir#:1
  wNotes=on  sortOrder:rid,rpid

 

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