Bil Cancer Research Results

Bil, Bilirubin: Click to Expand ⟱
Source:
Type:
Bilirubin a yellow pigment formed by the breakdown of heme (from red blood cells), is traditionally known for its role in liver function and jaundice.
Bilirubin as an Antioxidant (Cancer Protection)
-Moderately elevated bilirubin levels are associated with reduced cancer risk
-Bilirubin or synthetic analogs (e.g. bilirubin nanoparticles) are being studied for, Cancer prevention, and Reducing chemo side effects via oxidative stress protection.

In contrast, very high bilirubin levels in patients often indicate:
-Liver metastasis or hepatocellular carcinoma (HCC)



Scientific Papers found: Click to Expand⟱
5883- CAR,    Safety and tolerability of carvacrol in healthy subjects: a phase I clinical study
- Trial, Nor, NA
*Dose↝, *HDL↓, *Bil↓, *Iron↓, *toxicity↓,
6347- DRE,    Protective Effects of Taraxacum officinale L. (Dandelion) Root Extract in Experimental Acute on Chronic Liver Failure
*hepatoP↑, *AST↓, *ALAT↓, *ALP↓, *Bil↓, *creat↓, *TOS↑,
6385- Eug,    Anticancer potential of eugenol in hepatocellular carcinoma through modulation of oxidative stress, inflammation, apoptosis, and proliferation mechanisms
- in-vivo, HCC, HepG2
tumCV↓, TumCMig↓, *ALAT↓, *AST↓, *ALP↓, *Bil↓, *CEA↓, *lipid-P↓, *TNF-α↓, *IL1β↓, NF-kB↓, CXCR3↓, HRAS↓, KRAS↓, Ki-67↓, *GSH↑, *GPx↑, *SOD↑, *NRF2↑, P53↑, BAX↑, DR4↑, DR5↑,
3844- Moringa,    Review of the Safety and Efficacy of Moringa oleifera
- Review, NA, NA
*antiOx↑, *RenoP↑, *hepatoP↑, *radioP↑, *eff↑, *toxicity↓, *ROS↓, *lipid-P↓, *DNAdam↓, *Catalase↑, *SOD↑, *GPx↑, *GSR↑, *GSTs↑, *AST↓, *ALAT↓, *ALP↓, *Bil↓,

Showing Research Papers: 1 to 4 of 4

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 4

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned

CXCR3↓, 1,  

Cell Death

BAX↑, 1,   DR4↑, 1,   DR5↑, 1,  

Transcription & Epigenetics

tumCV↓, 1,  

DNA Damage & Repair

P53↑, 1,  

Proliferation, Differentiation & Cell State

HRAS↓, 1,  

Migration

Ki-67↓, 1,   KRAS↓, 1,   TumCMig↓, 1,  

Immune & Inflammatory Signaling

NF-kB↓, 1,  

Clinical Biomarkers

Ki-67↓, 1,   KRAS↓, 1,  
Total Targets: 13

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

antiOx↑, 1,   Bil↓, 4,   Catalase↑, 1,   GPx↑, 2,   GSH↑, 1,   GSR↑, 1,   GSTs↑, 1,   HDL↓, 1,   Iron↓, 1,   lipid-P↓, 2,   NRF2↑, 1,   ROS↓, 1,   SOD↑, 2,   TOS↑, 1,  

Core Metabolism/Glycolysis

ALAT↓, 3,  

DNA Damage & Repair

DNAdam↓, 1,  

Migration

CEA↓, 1,  

Immune & Inflammatory Signaling

IL1β↓, 1,   TNF-α↓, 1,  

Drug Metabolism & Resistance

Dose↝, 1,   eff↑, 1,  

Clinical Biomarkers

ALAT↓, 3,   ALP↓, 3,   AST↓, 3,   Bil↓, 4,   CEA↓, 1,   creat↓, 1,  

Functional Outcomes

hepatoP↑, 2,   radioP↑, 1,   RenoP↑, 1,   toxicity↓, 2,  
Total Targets: 31

Scientific Paper Hit Count for: Bil, Bilirubin
1 Carvacrol
1 Dandelion Root
1 Eugenol
1 Moringa oleifera
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1355  State#:%  Dir#:1
wNotes=0 sortOrder:rid,rpid

 

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