Wound Healing Cancer Research Results

Wound Healing, Wound Healing: Click to Expand ⟱
Source:
Type:
Wound Healing
Scientific Papers found: Click to Expand⟱
6556- BSB,    A Comprehensive Study of Therapeutic Applications of Chamomile
- Review, Nor, NA - Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*Inflam↓, anti-inflammatory, antioxidant, analgesic, antimicrobial, hepatoprotective, anti-allergic, anticancer, and anti-hypertensive agent
*antiOx↑,
*AntiBio↑,
*hepatoP↑,
*AntiCan↑,
*other↝, Two major species of chamomile widely used for health conditions are German chamomile (M. chamomilla L.) and Roman or English chamomile (Chamaemelum nobile syn. Anthemis nobilis L.) [6]
*toxicity↓, Chamomile is generally safe for consumption and is consumed as tea or tonic.
*Wound Healing↓, As a drug, it is useful in flatulence, colic, hysteria, intermittent fever, depression, ulcer, and wound healing
*Dose↝, The main constituents of the oil include terpenoids, mainly sesquiterpenes and α-bisabolol
*Dose↝, The major flavonoids present are apigenin, quercetin, patuletin, and luteolin in concentrations of 16.8%, 9.9%, 6.5%, and 1.9%, respectively, of course again depending on the species and cultivation.
*eff↝, The main components in German chamomile are terpenoid; α-bisabolol and its oxide azulenes, such as chamazulene (1–15%); and apigenin [12,16,17,18]. Roman chamomile, on the other hand, contains mainly angelic acid and tiglic acid esters
*ROS↓, e herb significantly reduced reactive oxygen species (ROS) levels, with the most prominent effect witnessed at a dose of 1000 mg/mL.
*TNF-α↓, significant reduction in TNF-α and IL-6 was observed, which suggests anti-inflammatory activities.
*IL6↓,
*other↝, Chamomile, being a natural antioxidant, possesses the ability to scavenge free radicals and, thus, can be effective for the management of neurological disorders such as Alzheimer’s disease, Parkinson’s disease, and cerebral ischemia
*AST↓, aqueous chamomile extracts reduced the levels of AST and ALT by 33–37%.
*ALAT↓,

6526- CRV,    Multi-targeted effects of D-carvone against Non-Small Cell Lung Cancer (NSCLC): A network pharmacology-based study
- Review, NSCLC, NA
TumCP↓, CN significantly inhibited cell proliferation, clonogenicity, and wound healing potential while promoting apoptosis in a dose-dependent manner in H1299 and A549
Wound Healing↓,
Apoptosis↓,

6232- CUR,  Rad,  Chemo,    The Effectiveness of Curcumin in Treating Oral Mucositis Related to Radiation and Chemotherapy: A Systematic Review
- Review, Var, NA
*VEGF↑, Curcumin has been observed to stimulate vascular endothelial growth factor (VEGF) and epidermal growth factor (EGF), both of which are responsible for cell proliferation and activity, thus promoting faster tissue healing
*Wound Healing↓,
*NRF2↑, Curcumin activates Nrf2 and promotes the release of antioxidant enzymes such as SOD, catalase (CAT), glutathione (GSH), and GSH-px
*Catalase↑,
*SOD↑,
*GSH↑,
*ROS↓, curcumin possesses powerful antioxidant properties that enable it to neu- tralize ROS, reducing oxidative damage to mucosal cells

6446- SAO,    Alpha-Santalol, a Component of Sandalwood Oil Inhibits Migration of Breast Cancer Cells by Targeting the β-catenin Pathway
- in-vitro, BC, NA
Wnt↓, we demonstrate that α-santalol treatment targets Wnt/β-catenin pathway to inhibit migration of cultured breast cancer cells
β-catenin/ZEB1↓,
TumCMig↓,
Wound Healing↓, Exposure of MDA-MB 231 and MCF-7 cells to α-santalol resulted in a significant reduction in their migratory potential and wound healing ability.


Showing Research Papers: 1 to 4 of 4

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 4

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death(tgid=5) ⓘ

Apoptosis↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Wnt↓, 1,  

Migration(tgid=13) ⓘ

TumCMig↓, 1,   TumCP↓, 1,   β-catenin/ZEB1↓, 1,  

Functional Outcomes(tgid=23) ⓘ

Wound Healing↓, 2,  
Total Targets: 6

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiBio↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   Catalase↑, 1,   GSH↑, 1,   NRF2↑, 1,   ROS↓, 2,   SOD↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↝, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

VEGF↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

IL6↓, 1,   Inflam↓, 1,   TNF-α↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 2,   eff↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   AST↓, 1,   IL6↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   hepatoP↑, 1,   toxicity↓, 1,   Wound Healing↓, 2,  
Total Targets: 22

Scientific Paper Hit Count for: Wound Healing, Wound Healing
1 α-Bisabolol / Chamomile oil
1 Carvone
1 Curcumin
1 Radiotherapy/Radiation
1 Chemotherapy
1 α-Santalol/Sandalwood oil
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1383  State#:%  Dir#:1
  wNotes=on  sortOrder:rid,rpid

 

Home Page