OCLN Cancer Research Results

OCLN, Occludin: Click to Expand ⟱
Source:
Type:
Occludin
Target/Pathway: Occludin
Abbreviation: OCLN
Category: Tight junction / intestinal barrier
Direction in IBD: usually down
Cancer relevance: usually barrier-loss associated, especially in inflammation-linked colorectal cancer


Scientific Papers found: Click to Expand⟱
6011- CGA,    Chlorogenic Acid’s Role in Metabolic Health: Mechanisms and Therapeutic Potential
- Review, Nor, NA
*BioAv↓, *antiOx↑, *Inflam↓, *Bacteria↓, *hepatoP↑, *cardioP↑, *neuroP↑, *ROS↓, *NF-kB↓, *NRF2↑, *Obesity↓, *GutMicro↑, *AntiAg↑, *cardioP↑, *AntiDiabetic↑, *NLRP3↓, *OCLN↓, *VEGF↓, BioAv↝,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Drug Metabolism & Resistance

BioAv↝, 1,  
Total Targets: 1

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

antiOx↑, 1,   NRF2↑, 1,   ROS↓, 1,  

Migration

AntiAg↑, 1,  

Angiogenesis & Vasculature

VEGF↓, 1,  

Barriers & Transport

OCLN↓, 1,  

Immune & Inflammatory Signaling

Inflam↓, 1,   NF-kB↓, 1,  

Protein Aggregation

NLRP3↓, 1,  

Drug Metabolism & Resistance

BioAv↓, 1,  

Clinical Biomarkers

GutMicro↑, 1,  

Functional Outcomes

AntiDiabetic↑, 1,   cardioP↑, 2,   hepatoP↑, 1,   neuroP↑, 1,   Obesity↓, 1,  

Infection & Microbiome

Bacteria↓, 1,  
Total Targets: 17

Scientific Paper Hit Count for: OCLN, Occludin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1463  State#:%  Dir#:1
wNotes=0 sortOrder:rid,rpid

 

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