OCLN Cancer Research Results
OCLN, Occludin: Click to Expand ⟱
| Source: |
| Type: |
Occludin
Target/Pathway: Occludin
Abbreviation: OCLN
Category: Tight junction / intestinal barrier
Direction in IBD: usually down
Cancer relevance: usually barrier-loss associated, especially in inflammation-linked colorectal cancer
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Scientific Papers found: Click to Expand⟱
*BioAv↓, *antiOx↑, *Inflam↓, *Bacteria↓, *hepatoP↑, *cardioP↑, *neuroP↑, *ROS↓, *NF-kB↓, *NRF2↑, *Obesity↓, *GutMicro↑, *AntiAg↑, *cardioP↑, *AntiDiabetic↑, *NLRP3↓, *OCLN↓, *VEGF↓, BioAv↝,
Showing Research Papers: 1 to 1 of 1
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Drug Metabolism & Resistance ⓘ
BioAv↝, 1,
Total Targets: 1
Pathway results for Effect on Normal Cells:
Redox & Oxidative Stress ⓘ
antiOx↑, 1, NRF2↑, 1, ROS↓, 1,
Migration ⓘ
AntiAg↑, 1,
Angiogenesis & Vasculature ⓘ
VEGF↓, 1,
Barriers & Transport ⓘ
OCLN↓, 1,
Immune & Inflammatory Signaling ⓘ
Inflam↓, 1, NF-kB↓, 1,
Protein Aggregation ⓘ
NLRP3↓, 1,
Drug Metabolism & Resistance ⓘ
BioAv↓, 1,
Clinical Biomarkers ⓘ
GutMicro↑, 1,
Functional Outcomes ⓘ
AntiDiabetic↑, 1, cardioP↑, 2, hepatoP↑, 1, neuroP↑, 1, Obesity↓, 1,
Infection & Microbiome ⓘ
Bacteria↓, 1,
Total Targets: 17
Scientific Paper Hit Count for: OCLN, Occludin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:1463 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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