HRAS Cancer Research Results

HRAS, v-Ha-ras Harvey rat sarcoma viral oncogene homolog: Click to Expand ⟱
Source: CGL-Driver Genes
Type: Oncogene
HRAS (Harvey rat sarcoma viral oncogene homolog) is one of the three main RAS genes (HRAS, KRAS, and NRAS) that encode proteins involved in cell signaling pathways that control cell growth and differentiation. Mutations in HRAS can lead to uncontrolled cell proliferation and are associated with various types of cancer.
When mutated, HRAS can become constitutively active, leading to continuous signaling for cell division and survival, contributing to tumorigenesis.
Scientific Papers found: Click to Expand⟱
5673- Bor,    Calcium Fructoborate Prevents Skin Cancer Development in Balb-c Mice
- in-vivo, Nor, NA
HRAS↓, Hif1a↓, Akt↓, PTEN↓,
6385- Eug,    Anticancer potential of eugenol in hepatocellular carcinoma through modulation of oxidative stress, inflammation, apoptosis, and proliferation mechanisms
- in-vivo, HCC, HepG2
tumCV↓, TumCMig↓, *ALAT↓, *AST↓, *ALP↓, *Bil↓, *CEA↓, *lipid-P↓, *TNF-α↓, *IL1β↓, NF-kB↓, CXCR3↓, HRAS↓, KRAS↓, Ki-67↓, *GSH↑, *GPx↑, *SOD↑, *NRF2↑, P53↑, BAX↑, DR4↑, DR5↑,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned ⓘ

CXCR3↓, 1,  

Cell Death ⓘ

Akt↓, 1,   BAX↑, 1,   DR4↑, 1,   DR5↑, 1,  

Transcription & Epigenetics ⓘ

tumCV↓, 1,  

DNA Damage & Repair ⓘ

P53↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

HRAS↓, 2,   PTEN↓, 1,  

Migration ⓘ

Ki-67↓, 1,   KRAS↓, 1,   TumCMig↓, 1,  

Angiogenesis & Vasculature ⓘ

Hif1a↓, 1,  

Immune & Inflammatory Signaling ⓘ

NF-kB↓, 1,  

Clinical Biomarkers ⓘ

Ki-67↓, 1,   KRAS↓, 1,  
Total Targets: 16

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

Bil↓, 1,   GPx↑, 1,   GSH↑, 1,   lipid-P↓, 1,   NRF2↑, 1,   SOD↑, 1,  

Core Metabolism/Glycolysis ⓘ

ALAT↓, 1,  

Migration ⓘ

CEA↓, 1,  

Immune & Inflammatory Signaling ⓘ

IL1β↓, 1,   TNF-α↓, 1,  

Clinical Biomarkers ⓘ

ALAT↓, 1,   ALP↓, 1,   AST↓, 1,   Bil↓, 1,   CEA↓, 1,  
Total Targets: 15

Scientific Paper Hit Count for: HRAS, v-Ha-ras Harvey rat sarcoma viral oncogene homolog
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:147  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

Home Page