ANXi Cancer Research Results

ANXi, anxiety: Click to Expand ⟱
Source:
Type:

anxiety
Scientific Papers found: Click to Expand⟱
6471- 1,8-Cin,    The Effect of 1,8-Cineole Inhalation on Preoperative Anxiety: A Randomized Clinical Trial
- Trial, Nor, NA
*ANXi↓, Measures of anxiety, including A-VAS (P < 0.001), STAI (P = 0.005), and POMS (P < 0.001), were significantly lower in 1,8-cineole than in the control group and significantly greater in 1,8-cineole than in the eucalyptus group in A-VAS.

6828- EMD,    Neuroprotective effect of emodin against Alzheimer's disease via Nrf2 signaling in U251 cells and APP/PS1 mice
- in-vitro, AD, U251
*MMP↑, emodin ameliorated the dissipation of the mitochondrial membrane potential, inhibited the over-accumulation of reactive oxygen species, enhanced the expression levels of nuclear factor-erythroid-2-related factor 2 (Nrf2), haemeoxygenase-1, superoxide
*ROS↓,
*NRF2↑,
*HO-1↑,
*SOD↑, superoxide dismutase 1, Bcl-2 and catalase in addition to decreasing the expression levels of Bax.
*Bcl-2↑,
*Catalase↑,
*BAX↓,
*memory↑, In APP/PS1 mice, an 8-week course of emodin administration improved spatial memory and learning ability and decreased anxiety.
*ANXi↓,
*Aβ↓, decreased the deposition of Aβ, phosphorylated-τ and 4-hydroxy-2-nonenal in APP/PS1 mice
*antiOx↑, In addition, emodin exhibits antioxidative effects: In viral myocarditis, emodin alleviates oxidative stress by increasing myocardial SOD expression levels whilst decreasing malondialdehyde expression levels
*MDA↓,


Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   Catalase↑, 1,   HO-1↑, 1,   MDA↓, 1,   NRF2↑, 1,   ROS↓, 1,   SOD↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

MMP↑, 1,  

Cell Death(tgid=5) ⓘ

BAX↓, 1,   Bcl-2↑, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 1,  

Functional Outcomes(tgid=23) ⓘ

ANXi↓, 2,   memory↑, 1,  
Total Targets: 13

Scientific Paper Hit Count for: ANXi, anxiety
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1497  State#:%  Dir#:1
  wNotes=on  sortOrder:rid,rpid

 

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