Stroke Cancer Research Results

Stroke, Stroke: Click to Expand ⟱
Source:
Type:

Stroke: A stroke, sometimes referred to as a brain attack arises if the blood flow is obstructed to a particular region of the brain or if the blood vessels in the brain rupture.



Scientific Papers found: Click to Expand⟱
7228- EGb 761,    Current Perspectives on the Beneficial Role of Ginkgo biloba in Neurological and Cerebrovascular Disorders
- Review, AD, NA
*Dose↝, *PAF↑, *AntiAg↑, *BloodF↑, *Inflam↓, *neuroP↑, *Stroke↓, *Dose↝, *Sepsis↓, *memory↑,
7236- EGb 761,    Neuroprotective effects of bilobalide, a component of the Ginkgo biloba extract (EGb 761), in gerbil global brain ischemia
- in-vivo, Stroke, NA
*Dose↑, *Stroke↓,
7196- EGb 761,    Ginkgo biloba extract EGb 761 in patients with dementia and a history of cerebral infarction-meta-analysis of pooled data from randomised clinical trials
- Review, AD, NA - Review, Stroke, NA
*neuroP↑, *cognitive↑, *Stroke↓, *toxicity↓, Dose↝,
6925- Flav,    Important Flavonoids and Their Role as a Therapeutic Agent
- Review, Nor, NA
AntiCan↑, *antiOx↑, *Inflam↓, *AntiViral↑, *neuroP↑, *cardioP↑, *AChE↓, *cognitive↑, Risk↓, *Stroke↓, *AntiDiabetic↑, *AntiFungal↑,
6981- Form,    Formononetin: a review of its source, pharmacology, drug combination, toxicity, derivatives, and drug delivery systems
- Review, Var, NA - Review, AD, NA - Review, PSA, NA
BioAv↝, *memory↑, *ROS↓, *AChE↓, *NF-kB↓, *Keap1↝, *NRF2↑, *Inflam↓, *PGC-1α↝, *HO-1↓, *p‑tau↓, *cognitive↑, *BDNF↑, *5HT↑, *Stroke↓, *PARP1↓, *AIF↓, *Casp3↓, NP/CIPN↓, *neuroP↑, *NGF↑, *TNF-α↓, *IL1β↓, *IL18↓, *IL6↓, *VCAM-1↓, *pol-M2 MC↑, *hepatoP↑, *AST↓, *ALAT↓, *LC3II↑, *Beclin-1↑, *p62↑, *COX2↑, *MMP↑, *ATP↑, *GSH↑, *Catalase↑, *GPx↑, *MDA↓, *antiPs↑, *AntiDiabetic↑, *glucose↓, *Insulin↑, *GutMicro↑, *Obesity↓, COX2↓, cycD1/CCND1↓, TumCCA↑, EGFR↓, GSK‐3β↑, Mcl-1↓, *toxicity↓, TumCP↓, Hif1a↓, VEGF↓, ERK↓, LAMs↓, Cyt‑c↑, Casp9↑, Casp3↑, PARP↑, TumCD↑, mitA↑, BACH1↓, P53↓, ROS↑, PD-1↓, NF-kB↓, *Bacteria↓, *AntiViral↑, *mt-ROS?, *PI3K↓, *chemoP↑, ChemoSen↑, eff↑, *toxicity↓, *BioAv↑, *BioAv↑, *eff↑,
7028- GA,    Gallic acid: Pharmacological activities and molecular mechanisms involved in inflammation-related diseases
- Review, Nor, NA
*toxicity↓, *Inflam↓, *NF-kB↓, AntiTum↑, Bacteria↓, *AntiDiabetic↑, *Obesity↓, *AntiBio↑, *Stroke↓, *NO↓, *PGE2↓, *IL6↓, *MAPK↓, *TNF-α↓, *IL1β↓, *MCP1/CCL2↓, *ICAM-1↓, *TIMP1↓,
7218- GBE,    Efficacy and Safety of Ginkgo biloba in Patients with Acute Ischemic Stroke: A Systematic Review and Meta-Analysis
- Review, Stroke, NA
*Stroke↓, *eff↑, *toxicity↓, *other?,
1188- GBE,    The potential of Ginkgo biloba in the treatment of human diseases and the relationship to Nrf2-mediated antioxidant protection
- Review, Stroke, NA
*NRF2↑, *ROS↓, *Stroke↓,
7199- GGB,    Ginkgolide B Promotes Angiogenesis After Oxygen-Glucose Deprivation by Regulating AKT1 in bEnd.3 Cells
- in-vitro, Stroke, NA
*neuroP↑, *VEGF↑, *AKT1↑, *angioG↑, *Stroke↓,
7140- GI,    Benefits of Ginger and Its Constituent 6-Shogaol in Inhibiting Inflammatory Processes
- Review, Var, NA
*Dose↝, *Inflam↓, *COX2↓, *iNOS↓, *NF-kB↓, *MAPK?, *HO-1↑, *PGE2↓, *TNF-α↓, *IL6↓, *IL1β↓, *IFN-γ↓, *MCP1/CCL2↓, *MIP2↓, *RANTES↓, *MPO↓, *NO↓, *Stroke↓, *BrainVol↑, *MDA↓, *ROS↓, *GSH↑, *NRF2↑, *antiOx↑, NLRP3↓, HDAC1↓,
7267- Gink,    Neuroprotective Potential of Biflavone Ginkgetin: A Review
- Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*neuroP↑, *ROS↓, *Aβ↓, *Inflam↓, *Dose↝, *cardioP↑, TumCCA↑, Apoptosis↑, TumAuto↑, STAT↓, *Stroke↓,
7251- Gink,    Ginkgetin: A Promising Multitarget Agent for Diverse Diseases
- Review, Var, NA
*Inflam↓, *antiOx↓, AntiCan↑, *neuroP↑, *cardioP↑, *Bacteria↓, *ROS↓, *lipid-P↓, *NRF2↓, *Keap1↓, *NF-kB↓, *MAPK↓, MMP2↓, M2 MC↓, JAK2↓, STAT3↓, TumCP↓, Casp↑, ChemoSen↑, *BMD↑, *Aβ↓, *Stroke↓, *BioAv↓,
7256- Gink,    Neuroprotective effect of ginkgetin in experimental cerebral ischemia/reperfusion via apoptosis inhibition and PI3K/Akt/mTOR signaling pathway activation
- in-vivo, Stroke, NA
*Stroke↓, *Apoptosis↓, *Casp3↓, *BAX↓, *Bcl-2↑, *p‑Akt↑, *p‑mTOR↑,
7260- Gink,    Ginkgetin: A natural biflavone with versatile pharmacological activities
- Review, Var, NA - Review, Stroke, NA - Review, AD, NA
*AntiCan↑, *Inflam↓, *AntiBio↑, *neuroP↑, *TumCCA↑, Apoptosis↑, TumAuto↑, iNOS↓, COX2↓, PGE2↓, NF-kB↓, PLA2↓, *neuroP↑, *Stroke↓, *AntiFungal↓, *Bacteria↓, Bcl-xL↓, Bcl-2↓, Casp9↑, Casp3↑, cl‑PARP↑, IL6↓, STAT3↓, JAK1↓, survivin↓, COX2↓, IAP1↓, MMP2↓, MMP9↓, PTEN↑, SHP1↑, eff↑, TumVol↓, TumW↓, *toxicity↓, *ROS↓,
6880- Phen,    Network Pharmacology of Natural Polyphenols for Stroke: A Bioinformatic Approach to Drug Design
- Study, Nor, NA
*neuroP↑, *other↝, *Stroke↓,

Showing Research Papers: 1 to 15 of 15

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 15

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

PLA2↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

ROS↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 2,   Bcl-2↓, 1,   Bcl-xL↓, 1,   Casp↑, 1,   Casp3↑, 2,   Casp9↑, 2,   Cyt‑c↑, 1,   IAP1↓, 1,   iNOS↓, 1,   Mcl-1↓, 1,   survivin↓, 1,   TumCD↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

TumAuto↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

P53↓, 1,   PARP↑, 1,   cl‑PARP↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

cycD1/CCND1↓, 1,   mitA↑, 1,   TumCCA↑, 2,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ERK↓, 1,   GSK‐3β↑, 1,   HDAC1↓, 1,   PTEN↑, 1,   SHP1↑, 1,   STAT↓, 1,   STAT3↓, 2,  

Migration(tgid=13) ⓘ

BACH1↓, 1,   LAMs↓, 1,   MMP2↓, 2,   MMP9↓, 1,   TumCP↓, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

EGFR↓, 1,   Hif1a↓, 1,   VEGF↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2↓, 3,   IL6↓, 1,   JAK1↓, 1,   JAK2↓, 1,   M2 MC↓, 1,   NF-kB↓, 2,   PD-1↓, 1,   PGE2↓, 1,  

Protein Aggregation(tgid=19) ⓘ

NLRP3↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↝, 1,   ChemoSen↑, 2,   Dose↝, 1,   eff↑, 2,  

Clinical Biomarkers(tgid=22) ⓘ

EGFR↓, 1,   IL6↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 2,   AntiTum↑, 1,   NP/CIPN↓, 1,   Risk↓, 1,   TumVol↓, 1,   TumW↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 1,  
Total Targets: 58

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiBio↑, 2,   PAF↑, 1,   Stroke↓, 15,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   antiOx↑, 2,   Catalase↑, 1,   GPx↑, 1,   GSH↑, 2,   HO-1↓, 1,   HO-1↑, 1,   Keap1↓, 1,   Keap1↝, 1,   lipid-P↓, 1,   MDA↓, 2,   MPO↓, 1,   NRF2↓, 1,   NRF2↑, 3,   ROS↓, 6,   mt-ROS?, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↓, 1,   ATP↑, 1,   Insulin↑, 1,   MMP↑, 1,   PGC-1α↝, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AKT1↑, 1,   ALAT↓, 1,   glucose↓, 1,  

Cell Death(tgid=5) ⓘ

p‑Akt↑, 1,   Apoptosis↓, 1,   BAX↓, 1,   Bcl-2↑, 1,   Casp3↓, 2,   iNOS↓, 1,   MAPK?, 1,   MAPK↓, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

other?, 1,   other↝, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1↑, 1,   LC3II↑, 1,   p62↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

PARP1↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

p‑mTOR↑, 1,   PI3K↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 1,   TIMP1↓, 1,   VCAM-1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↑, 1,   NO↓, 2,   VEGF↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2↓, 1,   COX2↑, 1,   ICAM-1↓, 1,   IFN-γ↓, 1,   IL18↓, 1,   IL1β↓, 3,   IL6↓, 3,   Inflam↓, 8,   pol-M2 MC↑, 1,   MCP1/CCL2↓, 2,   MIP2↓, 1,   NF-kB↓, 4,   PGE2↓, 2,   RANTES↓, 1,   TNF-α↓, 3,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 1,   AChE↓, 2,   BDNF↑, 1,   BrainVol↑, 1,   NGF↑, 1,   p‑tau↓, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 2,   Dose↑, 1,   Dose↝, 4,   eff↑, 2,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   AST↓, 1,   BloodF↑, 1,   BMD↑, 1,   GutMicro↑, 1,   IL6↓, 3,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   AntiDiabetic↑, 3,   antiPs↑, 1,   cardioP↑, 3,   chemoP↑, 1,   cognitive↑, 3,   hepatoP↑, 1,   memory↑, 2,   neuroP↑, 10,   Obesity↓, 2,   toxicity↓, 6,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↓, 1,   AntiFungal↑, 1,   AntiViral↑, 2,   Bacteria↓, 3,   Sepsis↓, 1,  
Total Targets: 99

Scientific Paper Hit Count for: Stroke, Stroke
4 Ginkgetin
3 Ginkgo biloba-EGb 761
2 Ginkgo biloba
1 flavonoids
1 Formononetin
1 Gallic acid
1 Ginkgolide B
1 Ginger/6-Shogaol/Gingerol
1 Phenolic Acids
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1534  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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