TumCMig Cancer Research Results

TumCMig, Tumor cell migration: Click to Expand ⟱
Source:
Type:
Tumor cell migration is a critical process in cancer progression and metastasis, which is the spread of cancer cells from the primary tumor to distant sites in the body.
Scientific Papers found: Click to Expand⟱
5465- AF,    The Thioredoxin Reductase Inhibitor Auranofin Suppresses Pulmonary Metastasis of Osteosarcoma, But Not Local Progression
- in-vitro, OS, NA
TrxR↓, ROS↑, TumCMig↓,
1333- AG,    Astragalus polysaccharide inhibits breast cancer cell migration and invasion by regulating epithelial-mesenchymal transition via the Wnt/β-catenin signaling pathway
- in-vitro, BC, NA
TumCMig↓, TumCI↓, Ki-67↓, TumCP↓, Snail↓, Vim↓, E-cadherin↑, Wnt↓, β-catenin/ZEB1↓,
5444- AG,    A Systematic Review of Phytochemistry, Pharmacology and Pharmacokinetics on Astragali Radix: Implications for Astragali Radix as a Personalized Medicine
- Review, Var, NA
*Imm↑, *antiOx↑, *Inflam↓, AntiTum↑, eff↑, chemoP↑, Dose↝, TumCMig↓, TumCP↓, Akt↓, GSK‐3β↓, MMP2↓, MMP9↓, EMT↓, PI3K↓, Akt↓, NF-kB↓, Inflam↓, TGF-β1↓, TNF-α↓, IL6↓, Fas↓, FasL↓, NOTCH1↓, JNK↓, TumCG↓,
5433- AG,    Mechanisms of astragalus polysaccharide enhancing STM2457 therapeutic efficacy in m6A-mediated OSCC treatment
- vitro+vivo, OS, NA
other↓, TumCP↓, TumCMig↓, TumCI↓, EMT↓, E-cadherin↑, N-cadherin↓, TumCG↓,
5438- AG,    Mechanisms of astragalus polysaccharide enhancing STM2457 therapeutic efficacy in mA-mediated OSCC treatment
- vitro+vivo, NA, NA
TumCP↓, TumCMig↓, TumCI↓, EMT↓, E-cadherin↑, N-cadherin↓,
4416- AgNPs,    Efficacy of curcumin-synthesized silver nanoparticles on MCF-7 breast cancer cells
- in-vitro, BC, MCF-7
TumCMig↓, Apoptosis↑, BAX↑, P53↑, Bcl-2↓,
4555- AgNPs,    Silver nanoparticles from Dendropanax morbifera Léveille inhibit cell migration, induce apoptosis, and increase generation of reactive oxygen species in A549 lung cancer cells
- in-vitro, Lung, A549 - in-vitro, Liver, HepG2
*Bacteria↓, tumCV↓, selectivity↑, ROS↑, Apoptosis↑, TumCMig↓, AntiCan↑,
5147- AgNPs,    Size dependent anti-invasiveness of silver nanoparticles in lung cancer cells
- in-vitro, Lung, A549
TumCMig↓, TumCI↓, ROS↑, p‑NF-kB↑, selectivity↑, eff↝,
338- AgNPs,    Biogenic silver nanoparticles: In vitro and in vivo antitumor activity in bladder cancer
- vitro+vivo, Bladder, 5637
TumCD↑, Apoptosis↑, TumCMig↓, TumCP↓,
359- AgNPs,    Anti-cancer & anti-metastasis properties of bioorganic-capped silver nanoparticles fabricated from Juniperus chinensis extract against lung cancer cells
- in-vitro, Lung, A549 - in-vitro, Nor, HEK293
Casp3↑, Casp9↑, P53↑, ROS↑, MMP2↓, MMP9↓, TumCCA↑, *toxicity↓, TumCMig↓, TumCI↓,
5343- Ajoene,    The garlic compound ajoene covalently binds vimentin, disrupts the vimentin network and exerts anti-metastatic activity in cancer cells
- in-vitro, Cerv, HeLa - in-vitro, BC, MDA-MB-231
Vim↑, TumCI↓, TumCMig↓, TumMeta↓, Vim↓, other↝,
2660- AL,    Allicin: A review of its important pharmacological activities
- Review, AD, NA - Review, Var, NA - Review, Park, NA - Review, Stroke, NA
*Inflam↓, AntiCan↑, *antiOx↑, *cardioP↑, *hepatoP↑, *BBB↑, *Half-Life↝, *H2S↑, *BP↓, *neuroP↑, *cognitive↑, *neuroP↑, *ROS↓, *GutMicro↑, *LDH↓, *ROS↓, *lipid-P↓, *antiOx↑, *other↑, *PI3K↓, *Akt↓, *NF-kB↓, *NO↓, *iNOS↓, *PGE2↓, *COX2↓, *IL6↓, *TNF-α↓, *MPO↓, *eff↑, *NRF2↑, *Keap1↓, *TBARS↓, *creat↓, *LDH↓, *AST↓, *ALAT↓, *MDA↓, *SOD↑, *GSH↑, *GSTs↑, *memory↑, chemoP↑, IL8↓, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, Casp12↑, p38↑, Fas↑, P53↑, P21↑, CHK1↓, CycB/CCNB1↓, GSH↓, ROS↑, TumCCA↑, Hif1a↓, Bcl-2↓, VEGF↓, TumCMig↓, STAT3↓, VEGFR2↓, p‑FAK↓,
253- AL,    Allicin inhibits invasion and migration of breast cancer cells through the suppression of VCAM-1: Regulation of association between p65 and ER-α
- in-vitro, BC, MDA-MB-231
TumCMig↓, ERK↓, VCAM-1↓, NF-kB↓,
3442- ALA,    α‑lipoic acid modulates prostate cancer cell growth and bone cell differentiation
- in-vitro, Pca, 22Rv1 - in-vitro, Pca, C4-2B - in-vitro, Nor, 3T3
tumCV↓, TumCMig↓, TumCI↓, ROS↑, Hif1a↑, JNK↑, Casp↑, TumCCA↑, Apoptosis↑, selectivity↑,
295- ALA,    α-Lipoic acid suppresses migration and invasion via downregulation of cell surface β1-integrin expression in bladder cancer cells
- in-vitro, Bladder, T24/HTB-9
ITGB1↓, TumCMig↓, ERK↓, Akt↓,
297- ALA,    Insights on the Use of α-Lipoic Acid for Therapeutic Purposes
- Review, BC, SkBr3 - Review, neuroblastoma, SK-N-SH - Review, AD, NA
PDH↑, TumCG↓, ROS↑, AMPK↑, EGR4↓, Half-Life↓, BioAv↝, *GSH↑, *IronCh↑, *ROS↓, *antiOx↑, *neuroP↑, *Ach↑, *lipid-P↓, *IL1β↓, *IL6↓, TumCP↓, FDG↓, Apoptosis↑, AMPK↑, mTOR↓, EGFR↓, TumCI↓, TumCMig↓, *memory↑, *BioAv↑, *BioAv↝, *other↓, *other↝, *Half-Life↓, *BioAv↑, *ChAT↑, *GlucoseCon↑,
276- ALA,    Alpha lipoic acid diminishes migration and invasion in hepatocellular carcinoma cells through an AMPK-p53 axis
- in-vitro, HCC, HepG2 - in-vitro, HCC, Hep3B
P53↑, EMT↓, AMPK↑, cycD1/CCND1↓, TumCMig↓,
1124- ALA,    Alpha lipoic acid inhibits proliferation and epithelial mesenchymal transition of thyroid cancer cells
- in-vitro, Thyroid, BCPAP - in-vitro, Thyroid, HTH-83 - in-vitro, Thyroid, CAL-62 - in-vitro, Thyroid, FTC-133 - in-vivo, NA, NA
TumCP↓, AMPK↑, mTOR↓, TumCMig↓, TumCI↓, EMT↓, E-cadherin↑, β-catenin/ZEB1↓, Vim↓, Snail↓, Twist↓, TGF-β↓, p‑SMAD2↓, TumCG↓,
553- Anamu,    The anti-inflammatory and analgesic effects of a crude extract of Petiveria alliacea L. (Phytolaccaceae)
- in-vivo, NA, NA
TumCMig↓,
1093- And,    Andrographolide attenuates epithelial‐mesenchymal transition induced by TGF‐β1 in alveolar epithelial cells
- in-vitro, Lung, A549
TGF-β↓, TumCMig↓, MMP2↓, MMP9↓, ECM/TCF↓, p‑SMAD2↓, p‑SMAD3↓, SMAD4↓, p‑ERK↓, ROS↓, NOX4↓, SOD2↑, SIRT1↑, FOXO3↑,
1157- And,    Andrographolide suppresses the migratory ability of human glioblastoma multiforme cells by targeting ERK1/2-mediated matrix metalloproteinase-2 expression
- in-vitro, GBM, GBM8401 - in-vitro, GBM, U251
TumCI↓, TumCMig↓, MMP2↓, ERK↝,
1548- Api,    A comprehensive view on the apigenin impact on colorectal cancer: Focusing on cellular and molecular mechanisms
- Review, Colon, NA
*BioAv↓, *Half-Life∅, selectivity↑, *toxicity↓, Wnt/(β-catenin)↓, P53↑, P21↑, PI3K↓, Akt↓, mTOR↓, TumCCA↑, TumCI↓, TumCMig↓, STAT3↓, PKM2↓, EMT↓, cl‑PARP↑, Casp3↑, Bax:Bcl2↑, VEGF↓, Hif1a↓, Dose∅, GLUT1↓, GlucoseCon↓,
1565- Api,    Apigenin-7-glucoside induces apoptosis and ROS accumulation in lung cancer cells, and inhibits PI3K/Akt/mTOR pathway
- in-vitro, Lung, A549 - in-vitro, Nor, BEAS-2B - in-vitro, Lung, H1975
TumCP↓, Apoptosis↑, TumCMig↓, TumCI↓, Cyt‑c↑, MDA↑, GSH↓, ROS↑, PI3K↓, Akt↓, mTOR↓,
1545- Api,    The Potential Role of Apigenin in Cancer Prevention and Treatment
- Review, NA, NA
TNF-α↓, IL6↓, IL1α↓, P53↑, Bcl-xL↓, Bcl-2↓, BAX↑, Hif1a↓, VEGF↓, TumCCA↑, DNAdam↑, Apoptosis↑, CycB/CCNB1↓, cycA1/CCNA1↓, CDK1↓, PI3K↓, Akt↓, mTOR↓, IKKα↓, ERK↓, p‑Akt↓, p‑P70S6K↓, p‑S6↓, p‑ERK↓, p‑P90RSK↑, STAT3↓, MMP2↓, MMP9↓, TumCP↓, TumCMig↓, TumCI↓, Wnt/(β-catenin)↓,
2632- Api,    Apigenin inhibits migration and induces apoptosis of human endometrial carcinoma Ishikawa cells via PI3K-AKT-GSK-3β pathway and endoplasmic reticulum stress
- in-vitro, EC, NA
TumCP↓, TumCCA↑, Apoptosis↑, Bcl-2↓, BAX↑, Bak↑, Casp↑, ER Stress↑, Ca+2↑, ATF4↑, CHOP↑, ROS↑, MMP↓, TumCMig↓, TumCI↓, eff↑, P53↑, P21↑, Cyt‑c↑, Casp9↑, Casp3↑, Bcl-xL↓,
2641- Api,    Apigenin inhibits HGF-promoted invasive growth and metastasis involving blocking PI3K/Akt pathway and beta 4 integrin function in MDA-MB-231 breast cancer cells
- in-vitro, BC, MDA-MB-231
TumCMig↓, TumCI↓, ITGB4↓,
2593- Api,    Apigenin promotes apoptosis of 4T1 cells through PI3K/AKT/Nrf2 pathway and improves tumor immune microenvironment in vivo
- in-vivo, BC, 4T1
TumCP↓, TumCMig↓, TumCI↓, Apoptosis↑, MMP↑, ROS↑, p‑PI3K↓, PI3K↓, Akt↓, NRF2↓, AntiTum↑, OS↑,
172- Api,    Apigenin suppresses colorectal cancer cell proliferation, migration and invasion via inhibition of the Wnt/β-catenin signaling pathway
- in-vitro, CRC, SW480 - in-vitro, CRC, HTC15
Wnt/(β-catenin)↓, TCF↓, LEF1↓, TumCP↓, TumCMig↓, TumCI↓,
174- Api,    Downregulation of NEDD9 by apigenin suppresses migration, invasion, and metastasis of colorectal cancer cells
- in-vitro, CRC, SW480 - in-vitro, CRC, DLD1
NEDD9↓, TumCMig↓, TumCI↓,
3396- ART/DHA,    Progress on the study of the anticancer effects of artesunate
- Review, Var, NA
TumCP↓, TumCI↓, TumCMig↓, Apoptosis↑, Diff↑, TumAuto↑, angioG↓, TumCCA↑, ROS↑, AMPK↑, mTOR↑, ChemoSen↑, Tf↑, Ferroptosis↑, Ferritin↓, lipid-P↑, CDK1↑, CDK2↑, CDK4↑, CDK6↑, SIRT1↑, COX2↓, IL1β↓, survivin↓, DNAdam↑, RadioS↑,
5136- ART/DHA,    Dihydroartemisinin targets VEGFR2 via the NF-κB pathway in endothelial cells to inhibit angiogenesis
- in-vitro, Var, NA
angioG↓, TumCP↓, TumCMig↓, NF-kB↓,
574- ART/DHA,    Dihydroartemisinin suppresses glioma proliferation and invasion via inhibition of the ADAM17 pathway
TumCP↓, TumCMig↓, TumCI↓, MMP17↓, p‑EGFR↓, p‑Akt↓,
570- ART/DHA,    Artemisinin and its derivatives can significantly inhibit lung tumorigenesis and tumor metastasis through Wnt/β-catenin signaling
- vitro+vivo, NSCLC, A549 - vitro+vivo, NSCLC, H1299
TumCCA↑, CSCs↓, TumCI↓, TumCMig↓, TumCG↓, Wnt/(β-catenin)↓, Nanog↓, SOX2↓, OCT4↓, N-cadherin↓, Vim↓, E-cadherin↑,
2578- ART/DHA,  RES,    Synergic effects of artemisinin and resveratrol in cancer cells
- in-vitro, Liver, HepG2 - in-vitro, Cerv, HeLa
Dose↝, TumCMig↓, Apoptosis↑, necrosis↑, ROS↑, eff↑,
5415- ASA,    The Anti-Metastatic Role of Aspirin in Cancer: A Systematic Review
- Review, Var, NA
TumMeta↓, COX1↓, TXA2↓, AntiAg↑, EMT↓, TumCMig↓, TumCI↓, AMPK↑, cMyc↓, PGE2↓, Dose↑, RadioS↑, PD-L1↓, E-cadherin↑, EMT↓, Slug↓, Vim↓, Twist↓, MMP2↓, MMP9↓, other↑,
5398- Ash,    Withaferin-A inhibits colorectal cancer growth and metastasis by targeting the HSP90/HIF-1α/EMT axis
- in-vitro, CRC, HCT116 - in-vitro, CRC, SW48
TumCG↓, TumCMig↓, TumCI↓, HSP90↓, Hif1a↓, EMT↓,
3174- Ash,    Withaferin A Acts as a Novel Regulator of Liver X Receptor-α in HCC
- in-vitro, HCC, HepG2 - in-vitro, HCC, Hep3B - in-vitro, HCC, HUH7
NF-kB↓, angioG↓, Inflam↓, TumCP↓, TumCMig↓, TumCI↓, Sp1/3/4↓, VEGF↓, angioG↓, uPA↓, PDGF↓, MCP1↓, ICAM-1↓, *NRF2↑, *hepatoP↑,
1362- Ash,  GEM,    Synergistic Inhibition of Pancreatic Cancer Cell Growth and Migration by Gemcitabine and Withaferin A
- in-vitro, PC, PANC1 - in-vitro, PC, Hs766t
ChemoSen↑, ROS↑, Apoptosis↑, TumCMig↓, F-actin↓, YMcells↓, NF-kB↓,
1181- Ash,    Withaferin A inhibits Epithelial to Mesenchymal Transition in Non-Small Cell Lung Cancer Cells
- in-vitro, Lung, A549 - in-vitro, Lung, H1299
TumCMig↓, TumCI↓, EMT↓, p‑SMAD2↓, p‑SMAD3↓, p‑NF-kB↓,
1179- Ash,    Withaferin-A Inhibits Colon Cancer Cell Growth by Blocking STAT3 Transcriptional Activity
- in-vitro, CRC, HCT116 - in-vivo, NA, NA
TumCP↓, TumCMig↓, STAT3↓, TumVol↓, TumW↓,
1173- Ash,    Withaferin A inhibits proliferation of human endometrial cancer cells via transforming growth factor-β (TGF-β) signalling
- in-vitro, EC, K1 - in-vitro, Nor, THESCs
TumCP↓, *toxicity↓, Apoptosis↑, TumCCA↑, TumCMig↓, TumCI↓, p‑SMAD2↓, TGF-β↓, *toxicity↓,
5172- Ash,    Withaferin-A suppress AKT induced tumor growth in colorectal cancer cells
Akt↓, TumCP↓, TumCMig↓, TumCI↓, EMT↓, Snail↓, Slug↓, β-catenin/ZEB1↓, Vim↓, angioG↓,
4811- ASTX,    Astaxanthin reduces MMP expressions, suppresses cancer cell migrations, and triggers apoptotic caspases of in vitro and in vivo models in melanoma
- vitro+vivo, Melanoma, A375 - vitro+vivo, Melanoma, A2058
ROS↓, MMPs↓, TumCMig↓, TumMeta↓, TumCCA↑, antiOx↑, MMP1↓, MMP2↓, MMP9↓,
4810- ASTX,    Effects of Astaxanthin on the Proliferation and Migration of Breast Cancer Cells In Vitro
- in-vitro, BC, MDA-MB-231 - in-vitro, Nor, MCF10
TumCP↓, TumCMig↓, selectivity↑, *BDNF↑, *ROS↓, *TNF-α↓, *IL6↓, *IFN-γ↓, *NF-kB↓, BAX⇅, Bcl-2↓, *antiOx↑, radioP↑, ChemoSen↑,
4808- ASTX,    Anti-Tumor Effects of Astaxanthin by Inhibition of the Expression of STAT3 in Prostate Cancer
- in-vitro, Pca, DU145 - in-vivo, NA, NA
TumCP↓, STAT3↓, Apoptosis↑, TumCMig↓, TumCI↓,
4807- ASTX,    An overview of the anticancer activity of astaxanthin and the associated cellular and molecular mechanisms
- Review, Var, NA
*antiOx↑, *neuroP↑, AntiCan↑, TumCG↓, TumCD↑, TumCMig↓, ChemoSen↑, chemoP↑, *BioAv↓, TumCP↓, TumCCA↑, Apoptosis↑, BioAv↑,
147- ATG,  EGCG,  CUR,    Increased chemopreventive effect by combining arctigenin, green tea polyphenol and curcumin in prostate and breast cancer cells
- in-vitro, Pca, LNCaP - in-vitro, Pca, MCF-7
Bax:Bcl2↑, NF-kB↓, PI3K/Akt↓, STAT3↓, chemoPv↑, TumCP↓, TumCCA↑, TumCMig↓,
4980- ATV,    A review of effects of atorvastatin in cancer therapy
- Review, Var, NA
HMG-CoA↓, TumCP↓, TumCMig↓,
5362- AV,    Anti-cancer effects of aloe-emodin: a systematic review
- Review, Var, NA
AntiCan↑, eff↝, TumCP↓, TumCMig↓, TumCI↓, TumCCA↑, TumCD↑, MMP↓, ROS↑, Apoptosis↑, CDK1↓, CycB/CCNB1↓, Bcl-2↓, PCNA↓, ATP↓, ER Stress↑, cl‑Casp3↑, cl‑Casp9↑, cl‑PARP↑, MMP2↓, Ca+2↑, DNAdam↑, Akt↓, PKCδ↓, mTORC2↓, GSH↓, ChemoSen↑,
1098- BA,    Baicalein inhibits fibronectin-induced epithelial–mesenchymal transition by decreasing activation and upregulation of calpain-2
- in-vitro, Nor, MCF10 - in-vivo, NA, NA
*TumCMig↓, *F-actin↓, *E-cadherin↑, *ZO-1↑, *N-cadherin↓, *Vim↓, *Snail↓, *cal2↓, *Ca+2↝,

Showing Research Papers: 1 to 50 of 361
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 361

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 1,   Ferroptosis↑, 1,   GSH↓, 3,   lipid-P↑, 1,   MDA↑, 1,   NOX4↓, 1,   NRF2↓, 1,   ROS↓, 2,   ROS↑, 14,   SOD2↑, 1,   TrxR↓, 1,  

Metal & Cofactor Biology ⓘ

Ferritin↓, 1,   Tf↑, 1,  

Mitochondria & Bioenergetics ⓘ

ATP↓, 1,   MMP↓, 2,   MMP↑, 1,  

Core Metabolism/Glycolysis ⓘ

AMPK↑, 6,   cMyc↓, 1,   FDG↓, 1,   GlucoseCon↓, 1,   HMG-CoA↓, 1,   PDH↑, 1,   PI3K/Akt↓, 1,   PKM2↓, 1,   p‑S6↓, 1,   SIRT1↑, 2,  

Cell Death ⓘ

Akt↓, 9,   p‑Akt↓, 2,   Apoptosis↑, 16,   Bak↑, 1,   BAX↑, 3,   BAX⇅, 1,   Bax:Bcl2↑, 2,   Bcl-2↓, 6,   Bcl-xL↓, 2,   Casp↑, 2,   Casp12↑, 1,   Casp3↑, 4,   cl‑Casp3↑, 1,   Casp8↑, 1,   Casp9↑, 3,   cl‑Casp9↑, 1,   Cyt‑c↑, 3,   Fas↓, 1,   Fas↑, 1,   FasL↓, 1,   Ferroptosis↑, 1,   JNK↓, 1,   JNK↑, 1,   necrosis↑, 1,   p38↑, 1,   survivin↓, 1,   TumCD↑, 3,  

Kinase & Signal Transduction ⓘ

Sp1/3/4↓, 1,  

Transcription & Epigenetics ⓘ

other↓, 1,   other↑, 1,   other↝, 1,   tumCV↓, 2,   YMcells↓, 1,  

Protein Folding & ER Stress ⓘ

CHOP↑, 1,   ER Stress↑, 2,   HSP90↓, 1,  

Autophagy & Lysosomes ⓘ

TumAuto↑, 1,  

DNA Damage & Repair ⓘ

CHK1↓, 1,   DNAdam↑, 3,   P53↑, 7,   cl‑PARP↑, 2,   PCNA↓, 1,  

Cell Cycle & Senescence ⓘ

CDK1↓, 2,   CDK1↑, 1,   CDK2↑, 1,   CDK4↑, 1,   cycA1/CCNA1↓, 1,   CycB/CCNB1↓, 3,   cycD1/CCND1↓, 1,   P21↑, 3,   TumCCA↑, 13,  

Proliferation, Differentiation & Cell State ⓘ

CSCs↓, 1,   Diff↑, 1,   EMT↓, 11,   ERK↓, 3,   ERK↝, 1,   p‑ERK↓, 2,   FOXO3↑, 1,   GSK‐3β↓, 1,   mTOR↓, 5,   mTOR↑, 1,   mTORC2↓, 1,   Nanog↓, 1,   NOTCH1↓, 1,   OCT4↓, 1,   p‑P70S6K↓, 1,   p‑P90RSK↑, 1,   PI3K↓, 5,   p‑PI3K↓, 1,   SOX2↓, 1,   STAT3↓, 6,   TCF↓, 1,   TumCG↓, 7,   Wnt↓, 1,   Wnt/(β-catenin)↓, 4,  

Migration ⓘ

AntiAg↑, 1,   Ca+2↑, 2,   E-cadherin↑, 6,   F-actin↓, 1,   p‑FAK↓, 1,   ITGB1↓, 1,   ITGB4↓, 1,   Ki-67↓, 1,   LEF1↓, 1,   MMP1↓, 1,   MMP17↓, 1,   MMP2↓, 8,   MMP9↓, 6,   MMPs↓, 1,   N-cadherin↓, 3,   NEDD9↓, 1,   PDGF↓, 1,   PKCδ↓, 1,   Slug↓, 2,   p‑SMAD2↓, 4,   p‑SMAD3↓, 2,   SMAD4↓, 1,   Snail↓, 3,   TGF-β↓, 3,   TGF-β1↓, 1,   TumCI↓, 29,   TumCMig↓, 49,   TumCP↓, 25,   TumMeta↓, 3,   Twist↓, 2,   uPA↓, 1,   VCAM-1↓, 1,   Vim↓, 6,   Vim↑, 1,   β-catenin/ZEB1↓, 3,  

Angiogenesis & Vasculature ⓘ

angioG↓, 5,   ATF4↑, 1,   ECM/TCF↓, 1,   EGFR↓, 1,   p‑EGFR↓, 1,   EGR4↓, 1,   Hif1a↓, 4,   Hif1a↑, 1,   TXA2↓, 1,   VEGF↓, 4,   VEGFR2↓, 1,  

Barriers & Transport ⓘ

GLUT1↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX1↓, 1,   COX2↓, 1,   ICAM-1↓, 1,   IKKα↓, 1,   IL1α↓, 1,   IL1β↓, 1,   IL6↓, 2,   IL8↓, 1,   Inflam↓, 2,   MCP1↓, 1,   NF-kB↓, 6,   p‑NF-kB↓, 1,   p‑NF-kB↑, 1,   PD-L1↓, 1,   PGE2↓, 1,   TNF-α↓, 2,  

Hormonal & Nuclear Receptors ⓘ

CDK6↑, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 1,   BioAv↝, 1,   ChemoSen↑, 5,   Dose↑, 1,   Dose↝, 2,   Dose∅, 1,   eff↑, 3,   eff↝, 2,   Half-Life↓, 1,   RadioS↑, 2,   selectivity↑, 5,  

Clinical Biomarkers ⓘ

EGFR↓, 1,   p‑EGFR↓, 1,   Ferritin↓, 1,   IL6↓, 2,   Ki-67↓, 1,   PD-L1↓, 1,  

Functional Outcomes ⓘ

AntiCan↑, 4,   AntiTum↑, 2,   chemoP↑, 3,   chemoPv↑, 1,   OS↑, 1,   radioP↑, 1,   TumVol↓, 1,   TumW↓, 1,  
Total Targets: 190

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 6,   GSH↑, 2,   GSTs↑, 1,   Keap1↓, 1,   lipid-P↓, 2,   MDA↓, 1,   MPO↓, 1,   NRF2↑, 2,   ROS↓, 4,   SOD↑, 1,   TBARS↓, 1,  

Metal & Cofactor Biology ⓘ

IronCh↑, 1,  

Core Metabolism/Glycolysis ⓘ

ALAT↓, 1,   GlucoseCon↑, 1,   H2S↑, 1,   LDH↓, 2,  

Cell Death ⓘ

Akt↓, 1,   iNOS↓, 1,  

Transcription & Epigenetics ⓘ

Ach↑, 1,   other↓, 1,   other↑, 1,   other↝, 1,  

Proliferation, Differentiation & Cell State ⓘ

PI3K↓, 1,  

Migration ⓘ

Ca+2↝, 1,   cal2↓, 1,   E-cadherin↑, 1,   F-actin↓, 1,   N-cadherin↓, 1,   Snail↓, 1,   TumCMig↓, 1,   Vim↓, 1,   ZO-1↑, 1,  

Angiogenesis & Vasculature ⓘ

NO↓, 1,  

Barriers & Transport ⓘ

BBB↑, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   IFN-γ↓, 1,   IL1β↓, 1,   IL6↓, 3,   Imm↑, 1,   Inflam↓, 2,   NF-kB↓, 2,   PGE2↓, 1,   TNF-α↓, 2,  

Synaptic & Neurotransmission ⓘ

BDNF↑, 1,   ChAT↑, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 2,   BioAv↑, 2,   BioAv↝, 1,   eff↑, 1,   Half-Life↓, 1,   Half-Life↝, 1,   Half-Life∅, 1,  

Clinical Biomarkers ⓘ

ALAT↓, 1,   AST↓, 1,   BP↓, 1,   creat↓, 1,   GutMicro↑, 1,   IL6↓, 3,   LDH↓, 2,  

Functional Outcomes ⓘ

cardioP↑, 1,   cognitive↑, 1,   hepatoP↑, 2,   memory↑, 2,   neuroP↑, 4,   toxicity↓, 4,  

Infection & Microbiome ⓘ

Bacteria↓, 1,  
Total Targets: 66

Scientific Paper Hit Count for: TumCMig, Tumor cell migration
21 Curcumin
13 Quercetin
13 Shikonin
11 Berberine
10 Honokiol
9 Silymarin (Milk Thistle) silibinin
8 Apigenin (mainly Parsley)
8 Resveratrol
8 EGCG (Epigallocatechin Gallate)
8 Betulinic acid
8 Capsaicin
8 Sulforaphane (mainly Broccoli)
7 Ashwagandha(Withaferin A)
7 Thymoquinone
7 Magnolol
7 Magnetic Fields
7 Urolithin
6 Propolis -bee glue
6 Chlorogenic acid
6 Fisetin
6 Piperlongumine
6 Rosmarinic acid
5 Silver-NanoParticles
5 Alpha-Lipoic-Acid
5 Artemisinin
5 Baicalein
5 Carvacrol
5 Metformin
5 Phenethyl isothiocyanate
5 Piperine
4 Astragalus
4 Gemcitabine (Gemzar)
4 Astaxanthin
4 Boron
4 Luteolin
4 Pterostilbene
3 Radiotherapy/Radiation
3 Berbamine
3 Bacopa monnieri
3 brusatol
3 Caffeic acid
3 Chrysin
3 Deguelin
3 Garcinol
3 HydroxyTyrosol
3 Lycopene
3 salinomycin
3 Aflavin-3,3′-digallate
2 Allicin (mainly Garlic)
2 Andrographis
2 Arctigenin
2 Baicalin
2 Bufalin/Huachansu
2 Genistein (soy isoflavone)
2 Boswellia (frankincense)
2 Paclitaxel
2 Carnosic acid
2 Celecoxib
2 Celastrol
2 Chlorophyllin
2 Docetaxel
2 5-fluorouracil
2 Disulfiram
2 Copper and Cu NanoParticles
2 Ellagic acid
2 Emodin
2 Ferulic acid
2 Ginkgo biloba
2 Grapeseed extract
2 Juglone
2 Plumbagin
2 Magnetic Field Rotating
2 Nimbolide
2 Psoralidin
2 Cisplatin
2 Parthenolide
2 Ursolic acid
2 Vitamin C (Ascorbic Acid)
2 VitK3,menadione
1 Auranofin
1 Ajoene (compound of Garlic)
1 dibenzyl trisulphide(DTS) from Anamu
1 Aspirin -acetylsalicylic acid
1 Atorvastatin
1 Aloe anthraquinones
1 Biochanin A
1 Bevacizumab (brand Avastin)
1 Brucea javanica
1 Bromelain
1 selenomethionine
1 Bruteridin(bergamot juice)
1 Butyrate
1 Caffeic Acid Phenethyl Ester (CAPE)
1 Cannabidiol
1 chitosan
1 Selenium NanoParticles
1 Citric Acid
1 Oxaliplatin
1 Docosahexaenoic Acid
1 diet Short Term Fasting
1 Evodiamine
1 erastin
1 Fucoidan
1 Shilajit/Fulvic Acid
1 Gambogic Acid
1 Ginger/6-Shogaol/Gingerol
1 γ-linolenic acid (Borage Oil)
1 Graviola
1 Proanthocyanidins
1 Hydrogen Gas
1 HydroxyCitric Acid
1 Indole-3-carbinol
1 Licorice
1 Melatonin
1 doxorubicin
1 immunotherapy
1 Myricetin
1 Naringin
1 Niclosamide (Niclocide)
1 Oroxylin A
1 Orlistat
1 Propyl gallate
1 temozolomide
1 isoflavones
1 raloxifen
1 tamoxifen
1 Germacranolide
1 Sanguinarine
1 Sulfasalazine
1 Selenite (Sodium)
1 Thymol-Thymus vulgaris
1 Arsenic trioxide
1 β‐Elemene
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:326  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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