miR-155 Cancer Research Results

miR-155, miR-155: Click to Expand ⟱
Source:
Type: Onco-microRNA
miR-155 has been found to be overexpressed in various types of cancer, including breast, lung, colon, and lymphoma. This overexpression has been associated with cancer progression, metastasis, and poor prognosis.


Scientific Papers found: Click to Expand⟱
4707- CUR,    The Potential Role of Curcumin as a Regulator of microRNA in Colorectal Cancer: A Systematic Review
- Review, Var, NA
miR-497↑, miR-200c↑, miR-409-3p↑, miR-34a↑, miR-126↑, miR-145↑, miR-206↑, miR-491↑, miR-141↑, miR-429↑, miR-101↑, miR-15↑, miR-21↓, miR-155↓, miR-221↓, miR‐222↓, miR-17↓, miR-130a↓, miR-27a-3p↓, miR-20↓,
3069- RES,    Resveratrol Inhibits NLRP3 Inflammasome-Induced Pyroptosis and miR-155 Expression in Microglia Through Sirt1/AMPK Pathway
- in-vitro, Nor, N9
*antiOx↑, *Inflam↓, *ROS↓, *NF-kB↓, *AMPK↑, *SIRT1↑, *miR-155↓, *NLRP3↓,
3036- RosA,    Anti-Warburg effect of rosmarinic acid via miR-155 in colorectal carcinoma cells
- in-vitro, CRC, HCT8 - in-vitro, CRC, HCT116 - in-vitro, CRC, LS174T
GlucoseCon↓, lactateProd↓, Hif1a↓, Inflam↓, miR-155↓, STAT3↓, Glycolysis↓, IL6↓, Warburg↓,
1748- RosA,    The Role of Rosmarinic Acid in Cancer Prevention and Therapy: Mechanisms of Antioxidant and Anticancer Activity
- Review, Var, NA
AntiCan↑, *BioAv↝, *CardioT↓, *Iron↓, *ROS↓, *SOD↑, *Catalase↑, *GPx↑, *NRF2↑, MARK4↓, MMP9↓, TumCCA↑, Bcl-2↓, BAX↑, Apoptosis↑, E-cadherin↑, N-cadherin↓, Vim↓, Gli1↓, HDAC2↓, Warburg↓, Hif1a↓, miR-155↓, p‑PI3K↑, ROS↑, *IronCh↑,
1437- SFN,    Dietary Sulforaphane in Cancer Chemoprevention: The Role of Epigenetic Regulation and HDAC Inhibition
- Review, NA, NA
HDAC↓, HDAC1↓, HDAC2↓, HDAC3↓, HDAC8↓, eff↑, ac‑HSP90↑, DNMT1↓, DNMT3A↓, hTERT/TERT↓, NRF2↑, HO-1↑, NQO1↑, miR-155↓, miR-200c↑, SOX9↓, *toxicity↓,
978- SIL,    A comprehensive evaluation of the therapeutic potential of silibinin: a ray of hope in cancer treatment
- Review, NA, NA
PI3K↓, Akt↓, NF-kB↓, Wnt/(β-catenin)↓, MAPK↓, TumCP↓, TumCCA↑, Apoptosis↑, p‑EGFR↓, JAK2↓, STAT5↓, cycD1/CCND1↓, hTERT/TERT↓, AP-1↓, MMP9↓, miR-21↓, miR-155↓, Casp9↑, BID↑, ERK↓, Akt2↓, DNMT1↓, P53↑, survivin↓, Casp3↑, ROS↑,
2212- SK,    Shikonin Exerts an Antileukemia Effect against FLT3-ITD Mutated Acute Myeloid Leukemia Cells via Targeting FLT3 and Its Downstream Pathways
- in-vitro, AML, NA
FLT3↓, NF-kB↓, miR-155↓, Diff↑, TumCG↓,

Showing Research Papers: 1 to 7 of 7

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 7

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1)

HO-1↑, 1,   NQO1↑, 1,   NRF2↑, 1,   ROS↑, 2,  

Core Metabolism/Glycolysis(tgid=4)

GlucoseCon↓, 1,   Glycolysis↓, 1,   lactateProd↓, 1,   Warburg↓, 2,  

Cell Death(tgid=5)

Akt↓, 1,   Apoptosis↑, 2,   BAX↑, 1,   Bcl-2↓, 1,   BID↑, 1,   Casp3↑, 1,   Casp9↑, 1,   hTERT/TERT↓, 2,   MAPK↓, 1,   miR-497↑, 1,   survivin↓, 1,  

Kinase & Signal Transduction(tgid=6)

SOX9↓, 1,  

Transcription & Epigenetics(tgid=7)

miR-145↑, 1,   miR-21↓, 2,   miR-27a-3p↓, 1,   miR-409-3p↑, 1,  

Protein Folding & ER Stress(tgid=8)

ac‑HSP90↑, 1,  

DNA Damage & Repair(tgid=10)

DNMT1↓, 2,   DNMT3A↓, 1,   P53↑, 1,  

Cell Cycle & Senescence(tgid=11)

cycD1/CCND1↓, 1,   TumCCA↑, 2,  

Proliferation, Differentiation & Cell State(tgid=12)

Diff↑, 1,   ERK↓, 1,   FLT3↓, 1,   Gli1↓, 1,   HDAC↓, 1,   HDAC1↓, 1,   HDAC2↓, 2,   HDAC3↓, 1,   HDAC8↓, 1,   miR-101↑, 1,   miR-34a↑, 1,   miR-429↑, 1,   PI3K↓, 1,   p‑PI3K↑, 1,   STAT3↓, 1,   STAT5↓, 1,   TumCG↓, 1,   Wnt/(β-catenin)↓, 1,  

Migration(tgid=13)

Akt2↓, 1,   AP-1↓, 1,   E-cadherin↑, 1,   MARK4↓, 1,   miR-130a↓, 1,   miR-141↑, 1,   miR-155↓, 6,   miR-20↓, 1,   miR-200c↑, 2,   miR-206↑, 1,   miR-221↓, 1,   miR-491↑, 1,   miR‐222↓, 1,   MMP9↓, 2,   N-cadherin↓, 1,   TumCP↓, 1,   Vim↓, 1,  

Angiogenesis & Vasculature(tgid=14)

p‑EGFR↓, 1,   Hif1a↓, 2,   miR-126↑, 1,   miR-15↑, 1,   miR-17↓, 1,  

Immune & Inflammatory Signaling(tgid=16)

IL6↓, 1,   Inflam↓, 1,   JAK2↓, 1,   NF-kB↓, 2,  

Drug Metabolism & Resistance(tgid=21)

eff↑, 1,  

Clinical Biomarkers(tgid=22)

p‑EGFR↓, 1,   hTERT/TERT↓, 2,   IL6↓, 1,  

Functional Outcomes(tgid=23)

AntiCan↑, 1,  
Total Targets: 79

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1)

antiOx↑, 1,   Catalase↑, 1,   GPx↑, 1,   Iron↓, 1,   NRF2↑, 1,   ROS↓, 2,   SOD↑, 1,  

Metal & Cofactor Biology(tgid=2)

IronCh↑, 1,  

Core Metabolism/Glycolysis(tgid=4)

AMPK↑, 1,   SIRT1↑, 1,  

Migration(tgid=13)

miR-155↓, 1,  

Immune & Inflammatory Signaling(tgid=16)

Inflam↓, 1,   NF-kB↓, 1,  

Protein Aggregation(tgid=19)

NLRP3↓, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↝, 1,  

Functional Outcomes(tgid=23)

CardioT↓, 1,   toxicity↓, 1,  
Total Targets: 17

Scientific Paper Hit Count for: miR-155, miR-155
2 Rosmarinic acid
1 Curcumin
1 Resveratrol
1 Sulforaphane (mainly Broccoli)
1 Silymarin (Milk Thistle) silibinin
1 Shikonin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:763  State#:%  Dir#:1
wNotes=0 sortOrder:rid,rpid

 

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