RUNX2 Cancer Research Results

RUNX2, Runt-related transcription factor 2: Click to Expand ⟱
Source:
Type:
RUNX2 (Runt-related transcription factor 2) is a transcription factor that plays a crucial role in the regulation of bone development and osteoblast differentiation.
RUNX2 is overexpressed in: breast, prostate, lung, osteosarcoma.
Scientific Papers found: Click to Expand⟱
5873- CA,    Carnosic acid serves as a dual Nrf2 activator and PTEN/AKT suppressor to inhibit traumatic heterotopic ossification
- vitro+vivo, Nor, NA
*NRF2↑, *NOX↓, *TAC↑, *ROS↓, *NQO1↑, *p‑PTEN↑, RUNX2↓, SOX9↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Kinase & Signal Transduction ⓘ

SOX9↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

RUNX2↓, 1,  
Total Targets: 2

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

NQO1↑, 1,   NRF2↑, 1,   ROS↓, 1,   TAC↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

p‑PTEN↑, 1,  

Cellular Microenvironment ⓘ

NOX↓, 1,  
Total Targets: 6

Scientific Paper Hit Count for: RUNX2, Runt-related transcription factor 2
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:776  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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