necrosis Cancer Research Results

necrosis, necrosis: Click to Expand ⟱
Source:
Type: type of cell death
Necrosis is a type of cell death that occurs when cells are damaged or injured, leading to the loss of cellular homeostasis and the eventual death of the cell. Necrosis is a non-programmed form of cell death, meaning that it is not a deliberate or controlled process, but rather a response to cellular damage or injury.


Scientific Papers found: Click to Expand⟱
5888- CAR,    Therapeutic application of carvacrol: A comprehensive review
- Review, Var, NA - Review, Stroke, NA - Review, Diabetic, NA - Review, Park, NA
*antiOx↑, *AntiCan↑, *AntiDiabetic↑, *cardioP↑, *Obesity↓, *hepatoP↑, *AntiAg↑, *Bacteria↓, *Imm↑, MMP2↓, MMP9↓, Apoptosis↓, MMP↓, ERK↓, PI3K↓, ALAT↓, *ROS↓, *Catalase↑, *SOD↑, *GPx↑, *AST↓, *LDH↓, *necrosis↓, ROS↑, TumCCA↑, CDK4↓, cycD1/CCND1↓, NOTCH↓, IL6↓, chemoP↑, *Pain↓, *neuroP↑, *TRPM7↓, *motorD↑, *NF-kB↓, *COX2↓, *MDA↓,
3468- MF,    An integrative review of pulsed electromagnetic field therapy (PEMF) and wound healing
- Review, NA, NA
*other↑, *necrosis↓, *IL6↑, *TGF-β↑, *iNOS↑, *MMP2↑, *MCP1↑, *HO-1↑, *Inflam↓, *IL1β↓, *IL6↓, *TNF-α↓, *BioAv↑, eff⇅, DNAdam↑, Apoptosis↑, ROS↑, TumCP↓, *ROS↓, *FGF↑,
3319- SIL,    Silymarin and neurodegenerative diseases: Therapeutic potential and basic molecular mechanisms
- Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*neuroP↑, *ROS↓, *Inflam↓, *Apoptosis↓, *BBB?, *tau↓, *NF-kB↓, *IL1β↓, *TNF-α↓, *IL4↓, *MAPK↓, *memory↑, *cognitive↑, *Aβ↓, *ROS↓, *lipid-P↓, *GSH↑, *MDA↓, *SOD↑, *Catalase↑, *AChE↓, *BChE↓, *p‑ERK↓, *p‑JNK↓, *p‑p38↓, *GutMicro↑, *COX2↓, *iNOS↓, *TLR4↓, *neuroP↑, *Strength↑, *AMPK↑, *MMP↑, *necrosis↓, *NRF2↑, *HO-1↑,
3648- SIL,    Silymarin/Silybin and Chronic Liver Disease: A Marriage of Many Years
- Review, NA, NA
*antiOx↑, *Inflam↓, *lipid-P↓, *necrosis↓, *hepatoP↑, *IL1↓, *IL6↓, *TNF-α↓, *IFN-γ↓, MAPK↓, Apoptosis↑, Cyt‑c↑, Casp3↑, Casp9↑, *PPARγ↑, *GLUT4↑, *HSPs↓, *HSP27↑, *Trx↑, *SIRT1↑, *ALAT↓, *GSH↑, *lipid-P↓, *TNF-α↓, TumCG↓, P21↑, CDK4↑,

Showing Research Papers: 1 to 4 of 4

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 4

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress

ROS↑, 2,  

Mitochondria & Bioenergetics

MMP↓, 1,  

Core Metabolism/Glycolysis

ALAT↓, 1,  

Cell Death

Apoptosis↓, 1,   Apoptosis↑, 2,   Casp3↑, 1,   Casp9↑, 1,   Cyt‑c↑, 1,   MAPK↓, 1,  

DNA Damage & Repair

DNAdam↑, 1,  

Cell Cycle & Senescence

CDK4↓, 1,   CDK4↑, 1,   cycD1/CCND1↓, 1,   P21↑, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State

ERK↓, 1,   NOTCH↓, 1,   PI3K↓, 1,   TumCG↓, 1,  

Migration

MMP2↓, 1,   MMP9↓, 1,   TumCP↓, 1,  

Immune & Inflammatory Signaling

IL6↓, 1,  

Drug Metabolism & Resistance

eff⇅, 1,  

Clinical Biomarkers

ALAT↓, 1,   IL6↓, 1,  

Functional Outcomes

chemoP↑, 1,  
Total Targets: 27

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

antiOx↑, 2,   Catalase↑, 2,   GPx↑, 1,   GSH↑, 2,   HO-1↑, 2,   lipid-P↓, 3,   MDA↓, 2,   NRF2↑, 1,   ROS↓, 4,   SOD↑, 2,   Trx↑, 1,  

Mitochondria & Bioenergetics

MMP↑, 1,  

Core Metabolism/Glycolysis

ALAT↓, 1,   AMPK↑, 1,   LDH↓, 1,   PPARγ↑, 1,   SIRT1↑, 1,  

Cell Death

Apoptosis↓, 1,   iNOS↓, 1,   iNOS↑, 1,   p‑JNK↓, 1,   MAPK↓, 1,   necrosis↓, 4,   p‑p38↓, 1,  

Transcription & Epigenetics

other↑, 1,  

Protein Folding & ER Stress

HSP27↑, 1,   HSPs↓, 1,  

Proliferation, Differentiation & Cell State

p‑ERK↓, 1,   FGF↑, 1,   TRPM7↓, 1,  

Migration

AntiAg↑, 1,   MMP2↑, 1,   TGF-β↑, 1,  

Barriers & Transport

BBB?, 1,   GLUT4↑, 1,  

Immune & Inflammatory Signaling

COX2↓, 2,   IFN-γ↓, 1,   IL1↓, 1,   IL1β↓, 2,   IL4↓, 1,   IL6↓, 2,   IL6↑, 1,   Imm↑, 1,   Inflam↓, 3,   MCP1↑, 1,   NF-kB↓, 2,   TLR4↓, 1,   TNF-α↓, 4,  

Synaptic & Neurotransmission

AChE↓, 1,   BChE↓, 1,   tau↓, 1,  

Protein Aggregation

Aβ↓, 1,  

Drug Metabolism & Resistance

BioAv↑, 1,  

Clinical Biomarkers

ALAT↓, 1,   AST↓, 1,   GutMicro↑, 1,   IL6↓, 2,   IL6↑, 1,   LDH↓, 1,  

Functional Outcomes

AntiCan↑, 1,   AntiDiabetic↑, 1,   cardioP↑, 1,   cognitive↑, 1,   hepatoP↑, 2,   memory↑, 1,   motorD↑, 1,   neuroP↑, 3,   Obesity↓, 1,   Pain↓, 1,   Strength↑, 1,  

Infection & Microbiome

Bacteria↓, 1,  
Total Targets: 71

Scientific Paper Hit Count for: necrosis, necrosis
2 Silymarin (Milk Thistle) silibinin
1 Carvacrol
1 Magnetic Fields
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:781  State#:%  Dir#:1
wNotes=0 sortOrder:rid,rpid

 

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