Let-7 Cancer Research Results

Let-7, Let-7: Click to Expand ⟱

Source:

Type: miRNAs

Let-7 is a family of microRNAs (miRNAs) that play a crucial role in regulating gene expression.
Let-7 miRNAs are known to target genes involved in cell proliferation, differentiation, and survival, and have been shown to act as tumor suppressors.

In cancer, let-7 miRNAs are often downregulated, leading to the upregulation of their target genes, which can contribute to cancer development and progression.

Scientific Papers found: Click to Expand⟱

7920-

VT,

Vitexin Induces Apoptosis in MCF-7 Breast Cancer Cells through the Regulation of Specific miRNAs Expression

in-vitro,

BC,

MCF7

Let-7↓, miR-17↓, Casp3↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Cell Death(tgid=5) ⓘ

Casp3↑, 1,

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Let-7↓, 1,

Angiogenesis & Vasculature(tgid=14) ⓘ

miR-17↓, 1,
Total Targets: 3

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: Let-7, Let-7

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells