Ginkgo biloba-EGb 761 / antiOx Cancer Research Results

EGb 761, Ginkgo biloba-EGb 761: Click to Expand ⟱
Features:
antiOx, anti-oxidant activities: Click to Expand ⟱
Source:
Type:
Various antioxidants such as Nrf2, SODs, catalase, GPxs, PRDXs, and GSTs are altered in different cancers and have been linked to prognosis. Their overexpression can correlate with aggressive tumor behavior and resistance to treatment in many contexts.


Scientific Papers found: Click to Expand⟱
7229- EGb 761,    Meta-analysis of the efficacy and safety of Ginkgo biloba extract for the treatment of dementia
- Review, AD, NA
*toxicity↓, *Dose↝, *ROS↓, *PAF↓, *memory↑, *BloodF↑, *antiOx↑, *Inflam↓, *Tinn↓,
3721- EGb 761,    Ginkgo biloba Extract in Alzheimer’s Disease: From Action Mechanisms to Medical Practice
- Review, AD, NA
*antiOx↑, *ROS↓, *SOD↑, *Catalase↑, *GSR↑, *MMP↑, *Inflam↓, *Aβ↓, *memory↑, *Dose↝, *BBB↑, *neuroP↑,
7219- EGb 761,    Ginkgo biloba Prevents Oxidative Stress-Induced Apoptosis Blocking p53 Activation in Neuroblastoma Cells
- in-vitro, Nor, SK-N-BE
*MMP↑, *Bax:Bcl2↓, *cl‑PARP↓, *i-antiOx↑, *mt-Apoptosis↓, *neuroP↑,
7193- EGb 761,  5-FU,    Ginkgo biloba extract 761 enhances 5-fluorouracil chemosensitivity in colorectal cancer cells through regulation of high mobility group-box 3 expression
- in-vitro, CRC, SW480 - in-vitro, CRC, SW-620
*antiOx↑, AntiCan↑, ChemoSen↑, selectivity↑, EMT↓, E-cadherin↑, Vim↓, HMGB1↓, other↝, chemoPv↑,
7206- GBE,  EGb 761,    Ginkgo biloba: A Leaf of Hope in the Fight against Alzheimer's Dementia: Clinical Trial Systematic Review
- Review, AD, NA
*Dose↝, *Inflam↓, *antiOx↑, *neuroP↑, *cognitive↑,

Showing Research Papers: 1 to 5 of 5

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 5

Pathway results for Effect on Cancer / Diseased Cells:


Transcription & Epigenetics(tgid=7)

other↝, 1,  

Proliferation, Differentiation & Cell State(tgid=12)

EMT↓, 1,  

Migration(tgid=13)

E-cadherin↑, 1,   Vim↓, 1,  

Immune & Inflammatory Signaling(tgid=16)

HMGB1↓, 1,  

Drug Metabolism & Resistance(tgid=21)

ChemoSen↑, 1,   selectivity↑, 1,  

Functional Outcomes(tgid=23)

AntiCan↑, 1,   chemoPv↑, 1,  
Total Targets: 9

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0)

PAF↓, 1,   Tinn↓, 1,  

Redox & Oxidative Stress(tgid=1)

antiOx↑, 4,   i-antiOx↑, 1,   Catalase↑, 1,   GSR↑, 1,   ROS↓, 2,   SOD↑, 1,  

Mitochondria & Bioenergetics(tgid=3)

MMP↑, 2,  

Cell Death(tgid=5)

mt-Apoptosis↓, 1,   Bax:Bcl2↓, 1,  

DNA Damage & Repair(tgid=10)

cl‑PARP↓, 1,  

Barriers & Transport(tgid=15)

BBB↑, 1,  

Immune & Inflammatory Signaling(tgid=16)

Inflam↓, 3,  

Protein Aggregation(tgid=19)

Aβ↓, 1,  

Drug Metabolism & Resistance(tgid=21)

Dose↝, 3,  

Clinical Biomarkers(tgid=22)

BloodF↑, 1,  

Functional Outcomes(tgid=23)

cognitive↑, 1,   memory↑, 2,   neuroP↑, 3,   toxicity↓, 1,  
Total Targets: 21

Scientific Paper Hit Count for: antiOx, anti-oxidant activities
5 Ginkgo biloba-EGb 761
1 5-fluorouracil
1 Ginkgo biloba
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:438  Target#:1103  State#:%  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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