TAZ Cancer Research Results

TAZ, Transcriptional Coactivator with PDZ-binding motif: Click to Expand ⟱
Source:
Type:
Transcriptional coactivators that play crucial roles in the Hippo signaling pathway, which regulates cell growth, proliferation, and survival.
TAZ and YAP are both phosphorylated and inhibited by the Hippo pathway, which leads to their cytoplasmic retention.
Scientific Papers found: Click to Expand⟱
431- CUR,    Curcumin suppresses the stemness of non-small cell lung cancer cells via promoting the nuclear-cytoplasm translocation of TAZ
- in-vitro, Lung, A549 - in-vitro, Lung, H1299
ALDH1A1↓, CD133↓, EpCAM↓, OCT4↓, TAZ↓, Hippo↑, p‑TAZ↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death ⓘ

Hippo↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

ALDH1A1↓, 1,   CD133↓, 1,   EpCAM↓, 1,   OCT4↓, 1,   TAZ↓, 1,   p‑TAZ↑, 1,  
Total Targets: 7

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: TAZ, Transcriptional Coactivator with PDZ-binding motif
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:678  State#:1  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

Home Page