MDA Cancer Research Results

MDA, Serum malondialdehyde: Click to Expand ⟱
Source:
Type:
MDA : malondialdehyde. The level of oxidative stress can be measured by assessing the MDA levels.
Since MDA is highly cytotoxic and carcinogenic agent it is frequently used as a biomarker of oxidative stress during major health problems such as cancer, etc.
Malondialdehyde (MDA) is the most widely used agent to estimate the extent of lipid peroxidation. Timely diagnosis of the condition followed by supplementation with antioxidants like beta-carotene, pro-vitamin A, vitamin A, vitamin C, vitamin E, lipoic acid, zinc, selenium, and spirulina can prevent potentially malignant disorders.
MDA is a lipid peroxidation marker


Scientific Papers found: Click to Expand⟱
6695- DFC,    Inhibition of lactate dehydrogenase A by diclofenac sodium induces apoptosis in HeLa cells through activation of AMPK
- in-vitro, Cerv, HeLa
other↝, Glycolysis↓, LDHA↓, Hypoxia↓, Apoptosis↑, lactateProd↓, ATP↓, mt-ROS↑, DNAdam↑, lipid-P↑, AMPK↑, p‑S6K↓, TumCP↓, Dose↝, selectivity↑, i-MDA↑, mtDam↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1)

lipid-P↑, 1,   i-MDA↑, 1,   mt-ROS↑, 1,  

Mitochondria & Bioenergetics(tgid=3)

ATP↓, 1,   mtDam↑, 1,  

Core Metabolism/Glycolysis(tgid=4)

AMPK↑, 1,   Glycolysis↓, 1,   lactateProd↓, 1,   LDHA↓, 1,   p‑S6K↓, 1,  

Cell Death(tgid=5)

Apoptosis↑, 1,  

Transcription & Epigenetics(tgid=7)

other↝, 1,  

DNA Damage & Repair(tgid=10)

DNAdam↑, 1,  

Migration(tgid=13)

TumCP↓, 1,  

Angiogenesis & Vasculature(tgid=14)

Hypoxia↓, 1,  

Drug Metabolism & Resistance(tgid=21)

Dose↝, 1,   selectivity↑, 1,  
Total Targets: 17

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: MDA, Serum malondialdehyde
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:570  State#:8  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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