AntiAge Cancer Research Results

AntiAge, Anti-aging: Click to Expand ⟱
Source:
Type:
Anti-aging strategies hold promise for improving overall health and potentially reducing cancer risk, the intricate interplay between the molecular mechanisms of aging and cancer requires careful consideration.
Scientific Papers found: Click to Expand⟱
3438- ALA,    The Potent Antioxidant Alpha Lipoic Acid
- Review, NA, NA - Review, AD, NA
*antiOx↑, *cardioP↑, *cognitive↑, *AntiAge↑, *Inflam↓, *AntiCan↑, *neuroP↑, *IronCh↑, *ROS↑, *Weight↓, *Ach↑, *ROS↓, *GSH↑, *lipid-P↓, *memory↑, *NRF2↑, *ChAT↑, *GlucoseCon↑, *Acetyl-CoA↑,
3443- ALA,    Molecular and Therapeutic Insights of Alpha-Lipoic Acid as a Potential Molecule for Disease Prevention
- Review, Var, NA - Review, AD, NA
*antiOx↑, *ROS↓, *IronCh↑, *cognitive↑, *cardioP↓, AntiCan↑, *neuroP↑, *Inflam↓, *BioAv↓, *AntiAge↑, *Half-Life↓, *BioAv↝, other↝, EGFR↓, Akt↓, ROS↓, TumCCA↑, p27/CDKN1B↑, PDH↑, Glycolysis↓, ROS↑, *eff↑, *memory↑, *motorD↑, *GutMicro↑,
3544- ALA,    Alpha lipoic acid for dementia
- Review, AD, NA
*antiOx↑, *BBB↑, *VitC↑, *VitE↑, *GSH↑, *IronCh↑, *neuroP↑, *NO↓, *cognitive↑, *AntiAge↑, *memory↑, *ROS↓,
3873- Carno,    Effects of dietary supplementation of carnosine on mitochondrial dysfunction, amyloid pathology, and cognitive deficits in 3xTg-AD mice
- in-vivo, AD, NA
*ROS↓, *IronCh↑, *Aβ↓, *AntiAge↑, *lipid-P↓, *cognitive↑, *memory∅,
3869- Carno,    Carnosine, Small but Mighty—Prospect of Use as Functional Ingredient for Functional Food Formulation
- Review, AD, NA - Review, Stroke, NA
*ROS↓, *IronCh↑, *AntiAge↑, *antiOx↑, *Inflam↓, *neuroP↑, *lipid-P↓, *toxicity↓, *NOX4↓, *SOD↑, *HNE↓, *IL6↓, *TNF-α↓, *IL1β↓, *Sepsis↓, *eff↑, *GABA↝, *Aβ↓, Glycolysis↓, AntiTum↑, p‑Akt↓, TumCCA↑, angioG↓, VEGFR2/KDR/Flk1↓, NF-kB↓,
6656- Cen,    Recent insights into therapeutic potential and nanostructured carrier systems of Centella asiatica: An evidence-based review
- Review, Var, NA - Review, AD, NA
AntiCan↑, *AntiDiabetic↑, *neuroP↑, *antiOx↑, *cardioP↑, *Inflam↓, *hepatoP↑, *AntiAge↑, *AST↓, *ALAT↓, *LDH↓, *lipid-P↓, Casp3↑, *memory↑, *Wound Healing↑, eff↑,
7406- Chy,    Antiamnesic activity of an ayurvedic formulation chyawanprash in mice
- in-vivo, AD, NA
*Dose↝, *memory↑, *TBARS↓, *GSH↑, *ROS↓, *cognitive↑, *AntiAge↑, *hepatoP↑, *antiOx↑, *LDL↓, *Inflam↓, *other↝, *AChE∅,
6629- Cic,    Chicoric Acid: Natural Occurrence, Chemical Synthesis, Biosynthesis, and Their Bioactive Effects
- Review, Nor, NA
*toxicity↓, *Inflam↓, *antiOx↑, *AntiAge↑, *eff↝, *Dose↝, *neuroP↑, *AntiViral↑,
6622- Cic,    Chicoric Acid Is an Antioxidant Molecule That Stimulates AMP Kinase Pathway in L6 Myotubes and Extends Lifespan in Caenorhabditis elegans
- in-vivo, Nor, NA
*ROS↓, *AMPK↑, *GPx↑, *SOD↑, *SOD2↑, *PGC-1α↑, *Akt↓, *mTOR↓, *Insulin↓, *antiOx↑, *AntiAge↑,
3997- CoQ10,    Coenzyme Q and Its Role in the Dietary Therapy against Aging
- Review, AD, NA
*AntiAge↑, *Inflam↓, *antiOx↑, *Apoptosis↓, *BioAv↑, *other↝, *cognitive↑, *DNAdam↓, *ER Stress↓,
3994- CoQ10,  Se,    Coenzyme Q10 Supplementation in Aging and Disease
- Review, AD, NA - Review, Park, NA
*AntiAge↑, *cardioP↑, *Inflam↓, *antiOx↑, *lipid-P↓, *QoL↑, *neuroP↑, *Dose↝, *BP↓, *IGF-1↑, *IGFBP1↑, *eff↑, *LDL↓, *HDL↑, *eff↑, *other↑, *RenoP↑, *ROS↓, *TNF-α↓, *IL6↓, *other↝, *other∅,
5780- CRMs,  HCAs,  RES,  Sper,  ASA  Caloric Restriction Mimetics against Age-Associated Disease: Targets, Mechanisms, and Therapeutic Potential
- Review, Var, NA
*OS↑, *AntiAge↑, *cardioP↑, *neuroP↑, AntiCan↑, *TNF-α↓, *Weight↓, *BP↓, *Inflam↓, *Insulin↓, *ROS↓, *AMPK↑, *mTOR↓, *SIRT1↑, CRM↑,
5792- CRMs,  HCA,  CUR,  EGCG,  GAR  Caloric restriction mimetics: natural/physiological pharmacological autophagy inducers
- Review, Nor, NA
*CRM↓, *Dose?, *AntiAge↑, *Acetyl-CoA↓, *SIRT1↑, *AMPK↑, *mTORC1↓, *AntiAge↑, chemoP↑,
6185- Cuc,    Cucurbitacin B: A review of its pharmacology, toxicity, and pharmacokinetics
- Review, Var, NA - Review, Arthritis, NA - Review, AD, NA
*Inflam↓, *antiOx↑, *hepatoP↑, *neuroP↑, *AntiCan↑, *toxicity↝, *BioAv↓, *HO-1↑, *NRF2↑, *NLRP3↑, *SOD↑, *SOD1↑, *ROS↓, *AntiAge↑, *ARE↑, *STAT↓, *NF-kB↓, *neuroG↑, *memory↑, ROS↑, NLRP3↑, CIP2A↓, Akt↓, STAT3↑, VEGFR2/KDR/Flk1↓, DNMTs↓, MAPK↓, YAP/TEAD↓, PI3K↓, Wnt↓, NOTCH↓, TumCCA↑, TumCG↓, TumCP↓, FAK↑, MMP9↓, TumAuto↑, toxicity↝, BioAv↓, Half-Life↝, BioAv↑, selectivity∅,
4654- CUR,    Stem Cell Therapy: Curcumin Does the Trick
- Review, Var, NA
*antiOx↑, *Inflam↓, AntiCan↑, chemoPv↑, *AntiAge↑, *neuroP↑, *Wound Healing↑,
3795- CUR,    Curcumin: A Golden Approach to Healthy Aging: A Systematic Review of the Evidence
- Review, AD, NA
*antiOx↑, *Inflam↓, *AntiAge↑, *AMPK↑, *SIRT1↑, *NF-kB↓, *mTOR↓, *NLRP3↓, *NADPH↓, *ROS↓, *COX2/PTGS2↓, *MCP1/CCL2↓, *IL1β↓, *IL17↓, *IL23↓, *TNF-α↓, *MPO↓, *IL10↑, *lipid-P↓, *SOD↑, *Aβ↓, *p‑tau↓, *GSK‐3β↓, *CDK5↓, *TXNIP↓, *NRF2↑, *NQO1↑, *HO-1↑, *OS↑, *memory↑, *BDNF↑, *neuroP↑, *BACE/β-secretase↓, *AChE↓, *LDL↓,
5188- dietMet,    Dietary methionine links nutrition and metabolism to the efficacy of cancer therapies
- in-vivo, Var, NA
AntiAge↑, MethCyc↓, TumCG↓, ChemoSen↑, RadioS↑, OS↑, GSH↓,
5066- dietSTF,    Intermittent and Periodic Fasting, Hormones, and Cancer Prevention
- Review, Var, NA
IGF-1↓, OS↑, AntiAge↑, glucose↓, Insulin↓,
6614- Ech,    Echinacea: a Miracle Herb against Aging and Cancer? Evidence In vivo in Mice
- in-vivo, Var, NA
*Imm↑, *AntiAge↑, OS↑, NK cell↑, PGE2↓, 5LO↓, COX2/PTGS2↓, Dose↝, eff↑,
5784- EGCG,    Dietary Epicatechin Promotes Survival of Obese Diabetic Mice and Drosophila melanogaster
- in-vivo, Nor, NA
*OS↑, *Inflam↓, *LDL↓, *AntiAge↑, *GSH↑, *SOD↑, *AMPKα↑, *Weight∅,
5519- EP,    Nanosecond Pulsed Electric Fields (nsPEFs) for Precision Intracellular Oncotherapy: Recent Advances and Emerging Directions
- Review, Var, NA
MMP↓, Ca+2↑, eff↑, ER Stress↑, selectivity↑, CSCs↓, CD44↓, CD133↓, ROS↑, Imm↑, DNAdam↑, MOMP↑, Cyt‑c↑, Casp9↑, Casp3↑, Casp9↑, TumCD↑, Fas↑, UPR↑, Dose↝, Dose↝, Dose↓, Dose↑, HMGB1↓, eff↑, EPR↑, ChemoSen↑, ETC↝, *AntiAge↑, *Hif1a↑, *SIRT1↑,
5523- EP,    Nanosecond pulsed electric field applications rejuvenate aging endothelial cells by rescuing mitochondrial-to-nuclear retrograde communication
- vitro+vivo, Nor, HUVECs
*MMP↑, *Hif1a↑, *SIRT1↑, *ROS↓, *AntiAge↑, *Dose↝, *angioG↑,
6584- EU,    Eurycoma longifolia: an overview on the pharmacological properties for the treatment of common cancer
- Review, Var, NA
*AntiAge↑, *Inflam↓, *antiOx↑, TumCD↑, Bcl-2↓, cl‑Casp7↑, cl‑PARP↑, BAX↑, P53↑, tumCV↓, selectivity↑, *testos↑, *PSA∅,
5392- FIS,  AsP,    Fisetin topical delivery via ascorbyl palmitate/hyaluronan-enhanced limosomes: a novel paradigm for preventing UVB-induced skin photoaging
- in-vivo, Nor, NA
eff↑, *antiOx↑, *MMP9↓, *TNF-α↓, *NF-kB↓, *SOD↑, *Catalase↑, *AntiAge↑, *Inflam↓, *JNK↓,
6896- FIS,    Fisetin is a senotherapeutic that extends health and lifespan
- in-vivo, Nor, NA
*AntiAge↑, *cellSen↑, *selectivity⇅,
6924- Flav,    Plant Flavonoids: Chemical Characteristics and Biological Activity
- Review, Nor, NA
*ROS↓, *antiOx↑, *Inflam↓, *Bacteria↓, *cardioP↑, AntiCan↑, *AntiAge↑, *AntiDiabetic↑, AntiViral↑, *BioAv↓, *AntiFungal↑,
7026- Fuc,    Fucoidan
- Review, AD, NA
*Inflam↓, *ROS↓, *BioAv↓, *GutMicro↑, *neuroP↑, *glucose↝, *AntiThr↑, *chemoP↑, *Half-Life↝, *BBB∅, *AntiAge↑, Risk↑,
4016- FulvicA,    Shilajit: A Natural Phytocomplex with Potential Procognitive Activity
- Review, AD, NA
*tau↓, *AntiAge↑, *Strength↑, *Dose↝, *BioAv↑, *antiOx↑, *memory↑, *Inflam↓, *cognitive↑, *neuroP↑, *toxicity↝, *toxicity↑,
7195- GBE,    Mitochondrial effects of Ginkgo biloba extract
- Review, AD, NA
*ROS↓, *mitResp↑, *AntiAge↑, *ATP↑, *neuroP↑, *ETC↑, *compI↑,
7126- Ge-132,    Immune activation of Bio-Germanium in a randomized, double-blind, placebo-controlled clinical trial with 130 human subjects: Therapeutic opportunities from new insights
- Trial, Nor, NA
AntiTum↑, AntiCan↑, *AntiAge↑, *AntiViral↑, *Inflam↓, *NK cell↑, *Imm↑, *TNF-α↑,
7253- Gink,    Ginkgetin Alleviates Inflammation and Senescence by Targeting STING
*cGAS–STING↓, *Inflam↓, *antiOx↑, *AntiAge↑, *DNAdam↓, *cellSen↓,
7488- H2,    Molecular hydrogen therapy: A "democratic" emerging strategy against aging and age-related diseases
- Review, Nor, NA
*antiOx↑, *Inflam↑, *toxicity↓, *AntiAge↑,
2071- HNK,    Identification of senescence rejuvenation mechanism of Magnolia officinalis extract including honokiol as a core ingredient
- Review, Nor, HaCaT
*ROS↓, *antiOx↑, *AntiAge↑, *MMP↑, *ECAR↓, *Glycolysis↓, *PAR-2↓, *CXCL12↑, *BMAL1↑, *mt-ROS↓, *OXPHOS↓,
5785- MET,    Metformin improves healthspan and lifespan in mice
- in-vivo, Nor, NA
*AntiDiabetic↑, *AntiAge↑, *toxicity⇅, *CRM↑, *Strength↑, *LDL↓, *AMPK↑, *TAC↑, *ROS↓, *Inflam↓, Risk↓, *cardioP↑, *ALAT↓, *NRF2↑, *SOD2↑, *TrxR1↑, *NQO1↑, *NQO2↑,
3499- MFrot,  MF,    Rotating magnetic field delays human umbilical vein endothelial cell aging and prolongs the lifespan of Caenorhabditis elegans
- in-vitro, Nor, HUVECs
*AntiAge↑, *AMPK↑, *mPGES-1↓, *Ca+2↑, *ER Stress↑, *OS↑, *ROS↓,
198- MFrot,  MF,    Biological effects of rotating magnetic field: A review from 1969 to 2021
- Review, Var, NA
AntiCan↑, breath↑, Pain↓, Appetite↑, Strength↑, BowelM↑, TumMeta↓, TumCCA↑, ETC↓, MMP↓, TumCD↑, selectivity↑, ROS↑, Casp3↑, TumCG↓, TumCCA↑, ChrMod↑, TumMeta↓, Imm↑, DCells↑, Akt↓, OS⇅, toxicity↓, QoL↑, hepatoP↑, Pain↓, Weight↑, Strength↑, Sleep↑, IL6↓, CD4+↑, CD8+↑, Ca+2↑, radioP↑, chemoP↑, *BMD↑, *AntiAge↑, *AMPK↑, *P21↓, *P53↓, *mTOR↓, *OS↑, *β-Endo↑, *5HT↓,
3849- MSM,    Beauty from within: Oral administration of a sulfur-containing supplement methylsulfonylmethane improves signs of skin ageing
- Human, Nor, NA
*Dose↝, *AntiAge↑,
3807- mushLions,    Searching for a Longevity Food, We Bump into Hericium erinaceus Primordium Rich in Ergothioneine: The “Longevity Vitamin” Improves Locomotor Performances during Aging
*AntiAge↑, *other↑, *NOS2↓, *COX2/PTGS2↓, *P53↑, *neuroP↑,
4703- PTS,  RES,    Pterostilbene and resveratrol: Exploring their protective mechanisms against skin photoaging - A scoping review
- NA, Nor, NA
*AntiAge↑, *eff↑, *Inflam↓, *AntiCan↑, *ROS↓, *Catalase↑, *GSR↑, *HO-1↑, *NAD↑, *NQO1↑, *SOD↑, *NRF2↑,
5781- RES,    Resveratrol improves health and survival of mice on a high-calorie diet
- in-vivo, Nor, NA
*AntiAge↑, *IGF-1↓, *AMPK↑, *CRM↑, *PGC-1α↑, *mtDam↓, *motorD↑, *hepatoP↑, *Dose↝,
5797- RES,    Enhancing the Delivery of Resveratrol in Humans: If Low Bioavailability is the Problem, What is the Solution?
- Review, Nor, NA
*AntiAge↑, *Dose↑, *BioAv↑, *BioAv↑, *BioAv∅, *BioAv↑, *BioAv↑, *BioAv↑, *BioAv↑,
3059- RES,    Resveratrol, an Nrf2 activator, ameliorates aging-related progressive renal injury
- in-vivo, Nor, HK-2
*RenoP↑, *Inflam↓, *NRF2↑, *HO-1↑, *SIRT1↑, *ROS↓, AntiAge↑,
4670- RES,  CUR,  EGCG,  TQ,    Targeting aging pathways with natural compounds: a review of curcumin, epigallocatechin gallate, thymoquinone, and resveratrol
- Review, Nor, NA
*antiOx↑, *Inflam↓, *AntiAge↑, *SIRT1↑, *SIRT3↑, *FOXO↑, *ROS↓,
7150- RES,    Modulation of the PI3K/Akt signaling pathway by resveratrol in cancer: molecular mechanisms and therapeutic opportunity
- Review, Var, NA
AntiTum↑, PI3K↓, Akt↓, *AntiAge↑, *SIRT1↑, *lipid-P↓, *ROS↓, *BioAv↓, *NRF2↑, *HO-1↑, SOD↑, HDAC1↓, PTEN↑, P53↑, TumCCA↑, TumCI↓, TumMeta↓, EMT↓, MMPs↓, MMP9↓, angioG↓, VEGF↓, EGFR↓, FGF21↓, HIF-1↓, *neuroP↑, *cardioP↑, BMPs↑, ROS↑, Vim↓, N-cadherin↓, MMP3↓, MMP13↓, E-cadherin↑, Ki-67↓,
3001- RosA,    Therapeutic Potential of Rosmarinic Acid: A Comprehensive Review
- Review, Var, NA
TumCP↓, Apoptosis↑, TumMeta↓, Inflam↓, *antiOx↑, *AntiAge↑, *ROS↓, BioAv↑, Dose↝, NRF2↑, P-gp/ABCB1↑, ATP↑, MMPs↓, cl‑PARP↓, Hif1a↓, GlucoseCon↓, lactateProd↓, Warburg↓, TNF-α↓, COX2/PTGS2↓, IL6↓, HDAC2↓, GSH↑, ROS↓, ChemoSen↑, *BG↓, *IL1β↓, *TNF-α↓, *IL6↓, *p‑JNK↓, *p38↓, *Catalase↑, *SOD↑, *GSTs↑, *VitC↑, *VitE↑, *GSH↑, *GutMicro↑, *cardioP↑, *ROS↓, *MMP↓, *lipid-P↓, *NRF2↑, *hepatoP↑, *neuroP↑, *P450↑, *HO-1↑, *AntiAge↑, *motorD↓,
3660- SFN,    Sulforaphane - role in aging and neurodegeneration
- Review, AD, NA
*antiOx↑, *Inflam↓, *NRF2↑, *NF-kB↓, *HDAC↓, *DNMTs↓, *neuroP↑, *AntiAge↑, *DNMT1↓, *DNMT3A↓, *memory↑, *HO-1↑, *ROS↓, *NO↓, *GSH↑, *NF-kB↓, *TNF-α↓, *IL10↑,
4891- Sper,    Spermidine as a promising anticancer agent: Recent advances and newer insights on its molecular mechanisms
- Review, Var, NA - Review, AD, NA
TumCCA↑, TumCP↓, TumCG↓, *Inflam↓, *antiOx↑, *neuroP↑, *cognitive↑, *Aβ↓, *mitResp↑, AntiCan↑, TumCD↑, TumAuto↑, *AntiAge↑, LC3B-II↑, ATG5↑, Beclin-1↑, mt-ROS↑, H2O2↑, Apoptosis↑, *ROS↑, ChemoSen↑, MMP↓, Cyt‑c↑,
5794- Sper,    Spermidine induces autophagy by inhibiting the acetyltransferase EP300
- in-vitro, Nor, U2OS
*EP300↓, *mTORC1↓, *CRM↑, *HATs↓, *p62↓, *AntiAge↑, AntiCan↑,
5782- Sper,    Cardioprotection and lifespan extension by the natural polyamine spermidine
- in-vivo, Nor, NA
cardioP↑, eff↓, AntiAge↑, BioAv↑, CRM↝,
3553- TQ,    Study Effectiveness and Stability Formulation Nanoemulsion of Black Cumin Seed (Nigella sativa L.) Essential Oil: A Review
- Review, Nor, NA
*AntiCan↑, *Inflam↓, *antiOx↑, *AntiAge↑, *hepatoP↑, *cardioP↑, *neuroP↑, *eff↑,

Showing Research Papers: 1 to 50 of 52
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 52

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

GSH↓, 1,   GSH↑, 1,   H2O2↑, 1,   NRF2↑, 1,   ROS↓, 2,   ROS↑, 5,   mt-ROS↑, 1,   SOD↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↑, 1,   ETC↓, 1,   ETC↝, 1,   Insulin↓, 1,   MMP↓, 3,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

CRM↑, 1,   CRM↝, 1,   FGF21↓, 1,   glucose↓, 1,   GlucoseCon↓, 1,   Glycolysis↓, 2,   lactateProd↓, 1,   MethCyc↓, 1,   PDH↑, 1,   Warburg↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 4,   p‑Akt↓, 1,   Apoptosis↑, 2,   BAX↑, 1,   Bcl-2↓, 1,   Casp3↑, 3,   cl‑Casp7↑, 1,   Casp9↑, 2,   Cyt‑c↑, 2,   Fas↑, 1,   MAPK↓, 1,   MOMP↑, 1,   p27/CDKN1B↑, 1,   TumCD↑, 4,   YAP/TEAD↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

BowelM↑, 1,   ChrMod↑, 1,   other↝, 1,   tumCV↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↑, 1,   UPR↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 1,   Beclin-1↑, 1,   LC3B-II↑, 1,   TumAuto↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 1,   DNMTs↓, 1,   P53↑, 2,   cl‑PARP↓, 1,   cl‑PARP↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA↑, 7,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CD133↓, 1,   CD44↓, 1,   CIP2A↓, 1,   CSCs↓, 1,   EMT↓, 1,   HDAC1↓, 1,   HDAC2↓, 1,   IGF-1↓, 1,   NOTCH↓, 1,   PI3K↓, 2,   PTEN↑, 1,   STAT3↑, 1,   TumCG↓, 4,   Wnt↓, 1,  

Migration(tgid=13) ⓘ

5LO↓, 1,   Ca+2↑, 2,   E-cadherin↑, 1,   FAK↑, 1,   Ki-67↓, 1,   MMP13↓, 1,   MMP3↓, 1,   MMP9↓, 2,   MMPs↓, 2,   N-cadherin↓, 1,   TumCI↓, 1,   TumCP↓, 3,   TumMeta↓, 4,   Vim↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 2,   EGFR↓, 2,   EPR↑, 1,   HIF-1↓, 1,   Hif1a↓, 1,   VEGF↓, 1,   VEGFR2/KDR/Flk1↓, 2,  

Barriers & Transport(tgid=15) ⓘ

P-gp/ABCB1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 1,   COX2/PTGS2↓, 2,   DCells↑, 1,   HMGB1↓, 1,   IL6↓, 2,   Imm↑, 2,   Inflam↓, 1,   NF-kB↓, 1,   NK cell↑, 1,   PGE2↓, 1,   TNF-α↓, 1,  

Protein Aggregation(tgid=19) ⓘ

NLRP3↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 3,   ChemoSen↑, 4,   Dose↓, 1,   Dose↑, 1,   Dose↝, 4,   eff↓, 1,   eff↑, 5,   Half-Life↝, 1,   RadioS↑, 1,   selectivity↑, 3,   selectivity∅, 1,  

Clinical Biomarkers(tgid=22) ⓘ

BMPs↑, 1,   EGFR↓, 2,   IL6↓, 2,   Ki-67↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 4,   AntiCan↑, 9,   AntiTum↑, 3,   Appetite↑, 1,   breath↑, 1,   cardioP↑, 1,   chemoP↑, 2,   chemoPv↑, 1,   hepatoP↑, 1,   OS↑, 3,   OS⇅, 1,   Pain↓, 2,   QoL↑, 1,   radioP↑, 1,   Risk↓, 1,   Risk↑, 1,   Sleep↑, 1,   Strength↑, 2,   toxicity↓, 1,   toxicity↝, 1,   Weight↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiViral↑, 1,   CD8+↑, 1,  
Total Targets: 141

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 25,   ARE↑, 1,   Catalase↑, 3,   compI↑, 1,   GPx↑, 1,   GSH↑, 6,   GSR↑, 1,   GSTs↑, 1,   HDL↑, 1,   HNE↓, 1,   HO-1↑, 7,   lipid-P↓, 8,   MPO↓, 1,   NOX4↓, 1,   NQO1↑, 3,   NRF2↑, 9,   OXPHOS↓, 1,   ROS↓, 25,   ROS↑, 2,   mt-ROS↓, 1,   SIRT3↑, 1,   SOD↑, 8,   SOD1↑, 1,   SOD2↑, 2,   TAC↑, 1,   TBARS↓, 1,   TrxR1↑, 1,   VitC↑, 2,   VitE↑, 2,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 5,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↑, 1,   ETC↑, 1,   Insulin↓, 2,   mitResp↑, 2,   MMP↓, 1,   MMP↑, 2,   mtDam↓, 1,   PGC-1α↑, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

Acetyl-CoA↓, 1,   Acetyl-CoA↑, 1,   ALAT↓, 2,   AMPK↑, 8,   BMAL1↑, 1,   CRM↓, 1,   CRM↑, 3,   ECAR↓, 1,   glucose↝, 1,   GlucoseCon↑, 1,   Glycolysis↓, 1,   LDH↓, 1,   LDL↓, 5,   NAD↑, 1,   NADPH↓, 1,   SIRT1↑, 8,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   Apoptosis↓, 1,   JNK↓, 1,   p‑JNK↓, 1,   p38↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

AMPKα↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

Ach↑, 1,   AntiThr↑, 1,   HATs↓, 1,   other↑, 2,   other↝, 3,   other∅, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↓, 1,   ER Stress↑, 1,   NQO2↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

p62↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 2,   DNMT1↓, 1,   DNMT3A↓, 1,   DNMTs↓, 1,   P53↓, 1,   P53↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

P21↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

EP300↓, 1,   FOXO↑, 1,   GSK‐3β↓, 1,   HDAC↓, 1,   IGF-1↓, 1,   IGF-1↑, 1,   IGFBP1↑, 1,   mTOR↓, 4,   mTORC1↓, 2,   neuroG↑, 1,   STAT↓, 1,  

Migration(tgid=13) ⓘ

Ca+2↑, 1,   CDK5↓, 1,   CXCL12↑, 1,   MMP9↓, 1,   TXNIP↓, 1,   β-Endo↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↑, 1,   Hif1a↑, 2,   NO↓, 2,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,   BBB∅, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

cellSen↓, 1,   cellSen↑, 1,   COX2/PTGS2↓, 2,   IL10↑, 2,   IL17↓, 1,   IL1β↓, 3,   IL23↓, 1,   IL6↓, 3,   Imm↑, 2,   Inflam↓, 27,   Inflam↑, 1,   MCP1/CCL2↓, 1,   mPGES-1↓, 1,   NF-kB↓, 5,   NK cell↑, 1,   PAR-2↓, 1,   PSA∅, 1,   TNF-α↓, 7,   TNF-α↑, 1,  

Cellular Microenvironment(tgid=17) ⓘ

cGAS–STING↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   AChE↓, 1,   AChE∅, 1,   BDNF↑, 1,   ChAT↑, 1,   GABA↝, 1,   tau↓, 1,   p‑tau↓, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 4,   BACE/β-secretase↓, 1,   NLRP3↓, 1,   NLRP3↑, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

testos↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 5,   BioAv↑, 8,   BioAv↝, 1,   BioAv∅, 1,   Dose?, 1,   Dose↑, 1,   Dose↝, 7,   eff↑, 6,   eff↝, 1,   Half-Life↓, 1,   Half-Life↝, 1,   P450↑, 1,   selectivity⇅, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 2,   AST↓, 1,   BG↓, 1,   BMD↑, 1,   BP↓, 2,   GutMicro↑, 3,   IL6↓, 3,   LDH↓, 1,   NOS2↓, 1,   PSA∅, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 48,   AntiCan↑, 4,   AntiDiabetic↑, 3,   cardioP↓, 1,   cardioP↑, 9,   chemoP↑, 1,   cognitive↑, 8,   hepatoP↑, 6,   memory↑, 9,   memory∅, 1,   motorD↓, 1,   motorD↑, 2,   neuroP↑, 20,   OS↑, 5,   QoL↑, 1,   RenoP↑, 2,   Strength↑, 2,   toxicity↓, 3,   toxicity↑, 1,   toxicity⇅, 1,   toxicity↝, 2,   Weight↓, 2,   Weight∅, 1,   Wound Healing↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 1,   AntiViral↑, 2,   Bacteria↓, 1,   Sepsis↓, 1,  
Total Targets: 183

Scientific Paper Hit Count for: AntiAge, Anti-aging
7 Resveratrol
4 Spermidine
4 Curcumin
3 Alpha-Lipoic-Acid
3 EGCG (Epigallocatechin Gallate)
2 Carnosine
2 Cichoric acid / Chicoric acid
2 Coenzyme Q10
2 Calorie Restriction Mimetics
2 Electrical Pulses
2 Fisetin
2 Magnetic Field Rotating
2 Magnetic Fields
2 Thymoquinone
1 Centella asiatica / Gotu kola → asiaticoside
1 Chyawanprash
1 Selenium
1 Hydroxycinnamic-acid
1 Aspirin
1 HydroxyCitric Acid
1 Garcinol
1 Cucurbitacin
1 diet Methionine-Restricted Diet
1 diet Short Term Fasting
1 Echinacea
1 Eurycomanone
1 Ascorbyl Palmitate
1 flavonoids
1 Fucoidan
1 Shilajit/Fulvic Acid
1 Ginkgo biloba
1 Germanium Organic/Ge-132 / propagermanium (organogermanium)
1 Ginkgetin
1 Hydrogen Gas
1 Honokiol
1 Metformin
1 Methylsulfonylmethane
1 Mushroom Lion’s Mane
1 Pterostilbene
1 Rosmarinic acid
1 Sulforaphane (mainly Broccoli)
1 Urolithin
1 Vitexin
1 Isovitexin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1245  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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