PONs Cancer Research Results
PONs, paraoxonase: Click to Expand ⟱
| Source: |
| Type: |
Paraoxonases refer to a family of enzymes—primarily PON1, PON2, and PON3—that are involved in the detoxification of oxidized lipids and the metabolism of various xenobiotics. Their roles in modulating oxidative stress and inflammation have attracted attention in cancer research.
-Upregulation in Some Tumors: In certain cancer types, elevated expression of paraoxonase enzymes may occur as an adaptive response to increased oxidative stress. For instance, some tumors demonstrate increased levels of PON2, which could help protect cancer cells from oxidative damage.
|
Scientific Papers found: Click to Expand⟱
| - |
Review, |
AD, |
NA |
|
|
|
- |
Review, |
Park, |
NA |
|
|
|
*neuroP↑, *NRF2↑, *PONs↑, *antiOx↑, *Inflam↓, *SIRT1↑, *eff↑, *ROS↓, *cognitive↑, *eff↑, *lipid-P↓, *GSH↑, *GPx↑, *SOD↑, *NRF2↑,
Showing Research Papers: 1 to 1 of 1
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Total Targets: 0
Pathway results for Effect on Normal Cells:
Redox & Oxidative Stress ⓘ
antiOx↑, 1, GPx↑, 1, GSH↑, 1, lipid-P↓, 1, NRF2↑, 2, ROS↓, 1, SOD↑, 1,
Core Metabolism/Glycolysis ⓘ
PONs↑, 1, SIRT1↑, 1,
Immune & Inflammatory Signaling ⓘ
Inflam↓, 1,
Drug Metabolism & Resistance ⓘ
eff↑, 2,
Functional Outcomes ⓘ
cognitive↑, 1, neuroP↑, 1,
Total Targets: 13
Scientific Paper Hit Count for: PONs, paraoxonase
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:1273 State#:% Dir#:2
wNotes=0 sortOrder:rid,rpid
Home Page