RKIP Cancer Research Results

RKIP, Raf Kinase Inhibitor Protein: Click to Expand ⟱

Source:

Type:

RKIP (Raf Kinase Inhibitor Protein)
-RKIP inhibits the Raf/MEK/ERK and NF-κB signaling pathways.
-It plays a role in regulating inflammation, cell survival, and apoptosis.
-RKIP expression is downregulated in AD brains.

Scientific Papers found: Click to Expand⟱

3727-

MF,

RKIP-Mediated NF-κB Signaling is involved in ELF-MF-mediated improvement in AD rat

in-vivo,

AD,

50 Hz and 400 µT ELF-MF for 60 days

rats

*cognitive↑, ELF-MF exposure partially improved the cognitive disorder, upregulated the levels of RKIP, TAK1, and the RKIP/TAK1 interaction, but downregulated p-IKK levels in AD rats
*RKIP↑, RKIP was significantly increased in the AD+MF group (P = 0.017) compared with the AD group at 14 d after ELF-MF exposure.
*p‑IKKα↓, downregulated at 7 d in the AD+MF group compared with both the Con group

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Total Targets: 0

Pathway results for Effect on Normal Cells:

Cell Death ⓘ

RKIP↑, 1,

Immune & Inflammatory Signaling ⓘ

p‑IKKα↓, 1,

Functional Outcomes ⓘ

cognitive↑, 1,
Total Targets: 3

Scientific Paper Hit Count for: RKIP, Raf Kinase Inhibitor Protein

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells