miR-194 Cancer Research Results

miR-194, miR-194: Click to Expand ⟱
Source:
Type:
miR-194 is a small, non-coding RNA enriched in epithelial tissues (notably liver, intestine, and kidney). Its physiologic role is to reinforce epithelial differentiation by repressing transcripts that drive motility, EMT, and stemness.
-Commonly DOWNREGULATED in many solid tumors during progression.
-Loss of miR-194 facilitates EMT, invasion, metastasis, and therapy resistance.
miR-194 is a tumor-suppressive microRNA whose loss marks transition toward EMT, invasion, and metastatic competence. As a biomarker, it is best used to interpret tumor state and risk—especially differentiation versus plasticity—rather than to diagnose cancer or choose a specific therapy.br
Scientific Papers found: Click to Expand⟱
7749- ISL,    Inhibition of COX-2, mPGES-1 and CYP4A by isoliquiritigenin blocks the angiogenic Akt signaling in glioma through ceRNA effect of miR-194-5p and lncRNA NEAT1
- in-vitro, GBM, U87MG
angioG↓, COX2/PTGS2↓, mPGES-1↓, CYP4A/CYP4A11/CYP4A22↓, FGF21↓, TGF-β↓, VEGF↓, miR-194↑, NEAT1↓,
4931- PEITC,    Phenethyl isothiocyanate (PEITC) suppresses prostate cancer cell invasion epigenetically through regulating microRNA-194
- in-vitro, Pca, LNCaP - in-vitro, Pca, PC3
Risk↓, miR-194↑, TumCI↓, MMP2↓, MMP9↓, BMP2↓, *chemoPv↑,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

CYP4A/CYP4A11/CYP4A22↓, 1,   NEAT1↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

FGF21↓, 1,  

Cell Death(tgid=5) ⓘ

BMP2↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

miR-194↑, 2,  

Migration(tgid=13) ⓘ

MMP2↓, 1,   MMP9↓, 1,   TGF-β↓, 1,   TumCI↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   VEGF↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   mPGES-1↓, 1,  

Functional Outcomes(tgid=23) ⓘ

Risk↓, 1,  
Total Targets: 14

Pathway results for Effect on Normal Cells:


Functional Outcomes(tgid=23) ⓘ

chemoPv↑, 1,  
Total Targets: 1

Scientific Paper Hit Count for: miR-194, miR-194
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1415  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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