PEF Cancer Research Results

PEF, Peak Expiratory Flow Rate; PEFR; Peak Flow: Click to Expand ⟱

Source:

Type:

Peak Expiratory Flow (PEF)

Aliases: Peak Expiratory Flow Rate; PEFR; Peak Flow

Definition: Peak expiratory flow is the maximum airflow achieved during a forceful expiration starting from full lung inflation.

Asthma relevance: PEF is commonly used to monitor variable airflow obstruction in asthma. Reduced PEF or excessive day-to-day variability can reflect worsening airway obstruction, while improvement can indicate bronchodilation or improved asthma control.

Direction:
PEF ↓ = generally adverse
PEF ↑ = generally beneficial when airflow is obstructed

Typical relationship:
Bronchoconstriction ↑ → Airway Resistance ↑ → Peak Expiratory Flow ↓

Scientific Papers found: Click to Expand⟱

7936-

TQ,

Effect of Nigella sativa supplementation on lung function and inflammatory mediators in partly controlled asthma: a randomized controlled trial

Trial,

Asthma,

*Dose↝, 1 and 2 g/day of N sativa, respectively, for 3 months along with maintenance inhaled therapy.
*FEV1↑, FEF25-75% and FEV1 (% predicted) increased significantly (P<.05) at both 6 and 12 weeks in the NS-2 group.
*PEF↑, FEF25-75% and FEV1 (% predicted) increased significantly (P<.05) at both 6 and 12 weeks in the NS-2 group.
*IgE↓, FeNO and serum IgE decreased significantly after 12 weeks in both the NS-1 and NS-2 groups vs baseline
*IFN-γ↑, Both doses of N sativa produced a significant increase in the serum IFN-γ at 12 weeks vs baseline
*eff↑, Significantly fewer patients had exacerbations in the NS-1 group
*IL4∅, The levels of IL-4, IL-10, IL-17A and the eotaxins did not change significantly in any of the three groups at any of the follow up visits.
*IL10∅,
*IL17∅,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Total Targets: 0

Pathway results for Effect on Normal Cells:

NA, unassigned(tgid=0) ⓘ

FEV1↑, 1, IgE↓, 1, PEF↑, 1,

Immune & Inflammatory Signaling(tgid=16) ⓘ

IFN-γ↑, 1, IL10∅, 1, IL17∅, 1, IL4∅, 1,

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 1, eff↑, 1,
Total Targets: 9

Scientific Paper Hit Count for: PEF, Peak Expiratory Flow Rate; PEFR; Peak Flow

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells