TTP Cancer Research Results

TTP, Time To Progression: Click to Expand ⟱

Source:

Type:

Time to Progression - TTP

Type: Clinical outcome / oncology efficacy endpoint

Function: Time to Progression is the interval from a defined starting point, such as treatment initiation or randomization, until objective disease progression. Death without documented progression is generally not counted as a progression event and may be censored, depending on the study definition.

Cancer: ↑ Longer TTP indicates delayed tumor progression and better disease control and is therefore generally favorable. ↓ TTP indicates earlier disease progression and is unfavorable.

Favorable Direction: ↑ Longer Time to Progression.

Scientific Papers found: Click to Expand⟱

8170-

Lap,

capec,

A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: updated efficacy and biomarker analyses

Trial,

BC,

399 women were randomized

Dose↝, TTP↑, OS↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

NA, unassigned(tgid=0) ⓘ

TTP↑, 1,

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 1,

Functional Outcomes(tgid=23) ⓘ

OS↑, 1,
Total Targets: 3

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: TTP, Time To Progression

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells