OS Cancer Research Results

OS, overall survival: Click to Expand ⟱
Source:
Type:
Overall survival

Scientific Papers found: Click to Expand⟱
2326- 2DG,    Caloric Restriction Mimetic 2-Deoxyglucose Alleviated Inflammatory Lung Injury via Suppressing Nuclear Pyruvate Kinase M2–Signal Transducer and Activator of Transcription 3 Pathway
- in-vivo, Nor, NA
PKM2↓, Inflam↓, TNF-α↓, IL6↓, OS↑,
5281- 3BP,    A translational study “case report” on the small molecule “energy blocker” 3-bromopyruvate (3BP) as a potent anticancer agent: from bench side to bedside
- Case Report, Var, NA
Glycolysis↓, mt-OXPHOS↓, ATP↓, selectivity↑, toxicity↝, OS↑, QoL↑,
5278- 3BP,    The effect of 3-bromopyruvate on human colorectal cancer cells is dependent on glucose concentration but not hexokinase II expression
- in-vitro, CRC, HCT116 - in-vitro, CRC, Caco-2 - in-vitro, CRC, SW48
ATP↓, TumCD↑, selectivity↑, toxicity↓, OS↑, HK2?, Cyt‑c↑, eff↑, p‑Akt↑,
5264- 3BP,    Candidate cancer drug suspected after death of three patients at an alternative medicine clinic
- Review, Var, NA
toxicity↑, Glycolysis↓, eff↑, OS↑, QoL↑, toxicity↝,
5467- AF,    Auranofin Inhibition of Thioredoxin Reductase Sensitizes Lung Neuroendocrine Tumor Cells (NETs) and Small Cell Lung Cancer (SCLC) Cells to Sorafenib as well as Inhibiting SCLC Xenograft Growth
- in-vitro, Lung, NA
TrxR↓, eff↑, Dose↝, OS↑, eff↑,
5440- AG,    Astragalus Injection Enhances the Sensitivity of Clinical Cancer Patients to Chemotherapy: A Systematic meta-Analysis
- Review, Var, NA
ChemoSen↑, OS↑,
4402- AgNPs,    Enhancement of Triple-Negative Breast Cancer-Specific Induction of Cell Death by Silver Nanoparticles by Combined Treatment with Proteotoxic Stress Response Inhibitors
- in-vitro, BC, BT549 - in-vitro, BC, MDA-MB-231 - in-vitro, Nor, MCF10
TumCD↑, selectivity↑, *toxicity↝, Dose↝, OS↑,
4394- AgNPs,    Silver nanoparticles provoke apoptosis of Dalton's ascites lymphoma in vivo by mitochondria dependent and independent pathways
- in-vivo, lymphoma, NA
OS↑, TumVol↓, Weight↑, AntiTum↑, Apoptosis↑, mtDam↑,
4362- AgNPs,    Enhancing Colorectal Cancer Radiation Therapy Efficacy using Silver Nanoprisms Decorated with Graphene as Radiosensitizers
- in-vitro, CRC, HCT116 - in-vitro, CRC, HT29 - in-vivo, NA, NA
eff↑, TumCG↓, OS↑, RadioS↑, eff↑, ROS↑, DNAdam↑, eff↝,
333- AgNPs,  HPT,    Enhancement effect of cytotoxicity response of silver nanoparticles combined with thermotherapy on C6 rat glioma cells
- in-vivo, GBM, NA
OS↑,
332- AgNPs,  Rad,    Enhancement of Radiosensitization by Silver Nanoparticles Functionalized with Polyethylene Glycol and Aptamer As1411 for Glioma Irradiation Therapy
- in-vivo, GBM, NA
OS↑,
331- AgNPs,  Rad,    Silver nanoparticles: a novel radiation sensitizer for glioma?
- vitro+vivo, GBM, NA
OS↑,
305- AgNPs,    Activity and pharmacology of homemade silver nanoparticles in refractory metastatic head and neck squamous cell cancer
- Case Report, HNSCC, NA
OS↑, Dose↓, BioAv↝, toxicity↓, Remission↑, other↝, other↝, other↝, Dose↝, BioAv↝,
345- AgNPs,    Antitumor activity of silver nanoparticles in Dalton’s lymphoma ascites tumor model
- vitro+vivo, lymphoma, NA
OS↑, ascitic↓,
5349- Akk,  immuno,    Improved survival in advanced melanoma patients treated with fecal microbiota transplantation using healthy donor stool in combination with anti-PD1: final results of the MIMic phase 1 trial
- Case Report, Melanoma, NA
eff↑, OS↑, eff↑,
287- ALA,  HCA,  Lyco,    Metabolic treatment of cancer: intermediate results of a prospective case series
PSA↓, OS↑,
290- ALA,  HCA,    A combination of alpha lipoic acid and calcium hydroxycitrate is efficient against mouse cancer models: preliminary results
- vitro+vivo, Melanoma, B16-F10
TumCG↓, OS↑,
271- ALA,  VitC,  LDN,    The Long-Term Survival of a Patient With Stage IV Renal Cell Carcinoma Following an Integrative Treatment Approach Including the Intravenous α-Lipoic Acid/Low-Dose Naltrexone Protocol
OS↑, Weight↑, TumVol↓,
274- ALA,  LDN,    Revisiting the ALA/N (alpha-lipoic acid/low-dose naltrexone) protocol for people with metastatic and nonmetastatic pancreatic cancer: a report of 3 new cases
- Human, PC, NA
OS↑,
5325- ALC,    L-Carnitine-supplementation in advanced pancreatic cancer (CARPAN) - a randomized multicentre trial
- Trial, PC, NA
Weight↑, QoL↑, OS↑,
5361- almon,    Abstract CT190: A multicenter, open-label, single-arm, phase II study: The third generation EGFR tyrosine kinase inhibitor almonertinib for pretreated EGFR T790M-positive locally advanced or metastatic non-small cell lung cancer (APOLLO)
- Trial, NSCLC, NA
EGFR↓, OS↑, Dose↝,
5360- almon,  BEV,    Case report: Almonertinib in combination with bevacizumab for leptomeningeal metastases from epidermal growth factor receptor-mutation non-small cell lung cancer: Case series
- Case Report, NSCLC, NA
BBB↑, Dose↝, eff↓, OS↑,
5357- almon,    AENEAS: A Randomized Phase III Trial of Aumolertinib Versus Gefitinib as First-Line Therapy for Locally Advanced or MetastaticNon-Small-Cell Lung Cancer With EGFR Exon 19 Deletion or L858R Mutations
- Trial, NSCLC, NA
EGFR↓, eff↝, OS↑,
4759- antiOx,  Chemo,    Potential Contributions of Antioxidants to Cancer Therapy: Immunomodulation and Radiosensitization
- Review, Var, NA
TumCD↑, TumCG↓, ROS⇅, eff↑, RadioS↑, TumCG↓, OS↑, toxicity∅, toxicity↑,
4760- antiOx,  Chemo,    Impact of antioxidant supplementation on chemotherapeutic efficacy: a systematic review of the evidence from randomized controlled trials
- Review, Var, NA
ChemoSen∅, OS↑, chemoP↑,
4765- antiOx,  Chemo,    Antioxidants as precision weapons in war against cancer chemotherapy induced toxicity – Exploring the armoury of obscurity
- Review, Var, NA
chemoP↑, ChemoSen↑, OS↑, Dose↑, Risk↓, eff↓,
1541- Api,  EGCG,    Prospective cohort comparison of flavonoid treatment in patients with resected colorectal cancer to prevent recurrence
- Human, NA, NA
OS↑, Remission↓, Dose∅,
2593- Api,    Apigenin promotes apoptosis of 4T1 cells through PI3K/AKT/Nrf2 pathway and improves tumor immune microenvironment in vivo
- in-vivo, BC, 4T1
TumCP↓, TumCMig↓, TumCI↓, Apoptosis↑, MMP↑, ROS↑, p‑PI3K↓, PI3K↓, Akt↓, NRF2↓, AntiTum↑, OS↑,
3671- Ash,    Withania somnifera showed neuroprotective effect and increase longevity in Drosophila Alzheimer’s disease model
- in-vivo, AD, NA
*OS↑, *BACE↓,
2002- Ash,    Ancient medicine, modern use: Withania somnifera and its potential role in integrative oncology
- Review, Var, NA
antiOx↑, Inflam↓, TumCP↓, OS↑, RadioS↑, radioP↑, chemoP↑,
5372- ATO,    Retinoic Acid and Arsenic Trioxide for Acute Promyelocytic Leukemia
- Trial, APL, NA
Remission↑, OS↑, toxicity↓,
5375- ATO,    Improved Outcome with ATRA-Arsenic Trioxide Compared to ATRA-Chemotherapy in Non-High Risk Acute Promyelocytic Leukemia – Updated Results of the Italian-German APL0406 Trial on the Extended Final Series
- Trial, APL, NA
eff↑, OS↑,
5374- ATO,    A pharmacokinetic and safety study of oral arsenic trioxide in patients with acute promyelocytic leukemia
- Trial, APL, NA
toxicity↓, OS↑,
5453- ATV,    Epidemiologic Analysis Along the Mevalonate Pathway Reveals Improved Cancer Survival in Patients Who Receive Statins Alone and in Combination With Bisphosphonates
- Trial, Var, NA
OS↑, eff↑, other↝,
5449- ATV,    Pleiotropic effects of statins: A focus on cancer
- NA, Var, NA
lipid-P↓, TumCG↓, Apoptosis↑, ChemoSen↑, RAS↓, HMG-CoA↓, HMGCR↓, LDL↓, toxicity↓, Risk↓, P21↑, HDAC↓, Bcl-2↓, BAX↑, BIM↑, Casp↑, cl‑PARP↑, MMP↓, ROS↑, angioG↓, TumMeta↓, PTEN↑, eff↑, OS↑, Remission↑,
4981- ATV,    Crosstalk between Statins and Cancer Prevention and Therapy: An Update
Apoptosis↑, selectivity↑, eff↑, HMG-CoA↓, *cardioP↑, OS↑, IL1β↓, IL6↓, IL8↓, TNF-α↓, TumAuto↑, Histones↝, ac‑H3↑, ac‑H4↑, HDAC↓,
5581- B-Gluc,    Chemo-Immunotherapy Using Lentinan for the Treatment of Gastric Cancer with Liver Metastases
- Human, GC, NA
OS↑,
5568- B-Gluc,  immuno,    Beta-glucans in oncology: revolutionizing treatment with immune power & tumor targeting
- Review, Var, NA
TNF-α↓, IL6↓, NF-kB↓, PD-L1↓, Imm↑, BAX↑, Bcl-2↓, TumCCA↑, angioG↓, VEGF↓, MMPs↓, OS↑, chemoP↑, eff↑, BioAv↑,
5567- B-Gluc,    Trained immunity: A new player in cancer immunotherapy
- Review, Var, NA
Imm↑, ROS↑, Apoptosis↑, OS↑, TumMeta↓, Dose↝,
5566- B-Gluc,    The effects of beta-glucan on human immune and cancer cells
- Review, Var, NA
Imm↑, *BioAv↓, OS↑, ChemoSen↑,
5576- B-Gluc,  Chemo,    Lentinan prolonged survival in patients with gastric cancer receiving S-1-based chemotherapy
- Trial, GC, NA
OS↑, eff↑,
5577- B-Gluc,    Lentinan progress in inflammatory diseases and tumor diseases
- Review, Var, NA - Review, IBD, NA
AntiTum↑, GutMicro↑, *Inflam↓, *TNF-α↓, *NF-kB↓, ChemoSen↑, OS↑, Imm↑, IL6↓, ERK↓, MAPK↓, *antiOx↑, eff↑,
5578- B-Gluc,    A multi-institutional prospective study of lentinan in advanced gastric cancer patients with unresectable and recurrent diseases: effect on prolongation of survival and improvement of quality of life. Kanagawa Lentinan Research Group
- Trial, GC, NA
OS↑, QoL↑,
5580- B-Gluc,    Lentinan, a Shiitake Mushroom β-Glucan, Downregulates the Enhanced PD-L1 Expression Induced by Platinum Compounds in Gastric Cancer Cells
- in-vitro, GC, MKN45
PD-L1↓, MAPK↓, OS↑, AntiTum↑, Imm↑,
5499- Ba,    Anti-cancer effects of baicalein in non-small cell lung cancer in-vitro and in-vivo
- vitro+vivo, Lung, H460 - vitro+vivo, Lung, A549
TumCP↓, Apoptosis↑, F-actin↓, TumVol↓, OS↑, 12LOX↓, VEGF↓, angioG↓,
1376- BBR,  immuno,    Berberine sensitizes immune checkpoint blockade therapy in melanoma by NQO1 inhibition and ROS activation
- in-vivo, Melanoma, NA
OS↑, ROS↑, NQO1↓, ICD↑,
5516- BEV,  immuno,  Chemo,    Targeting vascular normalization: a promising strategy to improve immune–vascular crosstalk in cancer immunotherapy
- Review, Var, NA
OS↑, eff↑,
5595- BEV,  Chemo,    Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for Metastatic Colorectal Cancer
- Human, CRC, NA
OS↑,
5623- Bif,    Bifidobacterium breve predicts the efficacy of anti-PD-1 immunotherapy combined with chemotherapy in Chinese NSCLC patients
- Study, NSCLC, NA
GutMicro↑, OS↑, eff↑,
5628- Bif,  immuno,    Bifidobacterium modulation of tumor immunotherapy and its mechanism
- Review, Var, NA
Imm↑, Risk↓, GutMicro↑, AntiTum↑, OS↑, selectivity↑, eff↑,

Showing Research Papers: 1 to 50 of 247
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 247

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress

antiOx↑, 1,   ICD↑, 1,   lipid-P↓, 1,   NQO1↓, 1,   NRF2↓, 1,   mt-OXPHOS↓, 1,   ROS↑, 5,   ROS⇅, 1,   TrxR↓, 1,  

Mitochondria & Bioenergetics

ATP↓, 2,   MMP↓, 1,   MMP↑, 1,   mtDam↑, 1,  

Core Metabolism/Glycolysis

12LOX↓, 1,   Glycolysis↓, 2,   Histones↝, 1,   HK2?, 1,   HMG-CoA↓, 2,   LDL↓, 1,   PKM2↓, 1,  

Cell Death

Akt↓, 1,   p‑Akt↑, 1,   Apoptosis↑, 6,   BAX↑, 2,   Bcl-2↓, 2,   BIM↑, 1,   Casp↑, 1,   Cyt‑c↑, 1,   MAPK↓, 2,   TumCD↑, 3,  

Transcription & Epigenetics

ac‑H3↑, 1,   ac‑H4↑, 1,   other↝, 4,  

Autophagy & Lysosomes

TumAuto↑, 1,  

DNA Damage & Repair

DNAdam↑, 1,   cl‑PARP↑, 1,  

Cell Cycle & Senescence

P21↑, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State

ERK↓, 1,   HDAC↓, 2,   HMGCR↓, 1,   PI3K↓, 1,   p‑PI3K↓, 1,   PTEN↑, 1,   RAS↓, 1,   TumCG↓, 5,  

Migration

F-actin↓, 1,   MMPs↓, 1,   TumCI↓, 1,   TumCMig↓, 1,   TumCP↓, 3,   TumMeta↓, 2,  

Angiogenesis & Vasculature

angioG↓, 3,   EGFR↓, 2,   VEGF↓, 2,  

Barriers & Transport

BBB↑, 1,  

Immune & Inflammatory Signaling

IL1β↓, 1,   IL6↓, 4,   IL8↓, 1,   Imm↑, 6,   Inflam↓, 2,   NF-kB↓, 1,   PD-L1↓, 2,   PSA↓, 1,   TNF-α↓, 3,  

Drug Metabolism & Resistance

BioAv↑, 1,   BioAv↝, 2,   ChemoSen↑, 5,   ChemoSen∅, 1,   Dose↓, 1,   Dose↑, 1,   Dose↝, 6,   Dose∅, 1,   eff↓, 2,   eff↑, 19,   eff↝, 2,   RadioS↑, 3,   selectivity↑, 5,  

Clinical Biomarkers

ascitic↓, 1,   EGFR↓, 2,   GutMicro↑, 3,   IL6↓, 4,   PD-L1↓, 2,   PSA↓, 1,  

Functional Outcomes

AntiTum↑, 5,   chemoP↑, 4,   OS↑, 49,   QoL↑, 4,   radioP↑, 1,   Remission↓, 1,   Remission↑, 3,   Risk↓, 3,   toxicity↓, 5,   toxicity↑, 2,   toxicity↝, 2,   toxicity∅, 1,   TumVol↓, 3,   Weight↑, 3,  
Total Targets: 98

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

antiOx↑, 1,  

Immune & Inflammatory Signaling

Inflam↓, 1,   NF-kB↓, 1,   TNF-α↓, 1,  

Protein Aggregation

BACE↓, 1,  

Drug Metabolism & Resistance

BioAv↓, 1,  

Functional Outcomes

cardioP↑, 1,   OS↑, 1,   toxicity↝, 1,  
Total Targets: 9

Scientific Paper Hit Count for: OS, overall survival
17 Magnetic Fields
15 Magnetic Field Rotating
14 Vitamin C (Ascorbic Acid)
12 Chemotherapy
12 Hydrogen Gas
10 Radiotherapy/Radiation
8 Silver-NanoParticles
8 immunotherapy
8 beta-glucans
8 diet Methionine-Restricted Diet
7 Selenium
6 Alpha-Lipoic-Acid
6 Dichloroacetate
6 diet Plant based
5 HydroxyCitric Acid
5 cetuximab
5 Curcumin
5 diet FMD Fasting Mimicking Diet
5 Bicarbonate(Sodium)
5 Phenylbutyrate
4 EGCG (Epigallocatechin Gallate)
4 capecitabine
4 Melatonin
4 Phenethyl isothiocyanate
4 Ramucirumab (CYRAMZA)
3 3-bromopyruvate
3 almonertinib
3 Bevacizumab (brand Avastin)
3 Anti-oxidants
3 Arsenic trioxide
3 Atorvastatin
3 Carvacrol
3 Oxygen, Hyperbaric
3 Exercise
3 diet Short Term Fasting
3 metronomic chemo
3 nicotinamide adenine dinucleotide
3 Sulfasalazine
3 Silymarin (Milk Thistle) silibinin
3 Shikonin
3 Selenite (Sodium)
3 Urolithin
2 Lycopene
2 low dose naltrexone
2 Apigenin (mainly Parsley)
2 Ashwagandha(Withaferin A)
2 Bifidobacterium
2 Docetaxel
2 Chlorogenic acid
2 Citric Acid
2 Calorie Restriction Mimetics
2 Resveratrol
2 Spermidine
2 Sulforaphane (mainly Broccoli)
2 Gemcitabine (Gemzar)
2 Orlistat
2 Honokiol
2 itraconazole
2 Juglone
2 Metformin
2 Propolis -bee glue
2 Piperine
2 doxorubicin
2 Thymoquinone
2 VitK3,menadione
1 2-DeoxyGlucose
1 Auranofin
1 Astragalus
1 Hyperthermia
1 Akkermansia
1 Acetyl-l-carnitine
1 Baicalein
1 Berberine
1 Brucea javanica
1 Bacopa monnieri
1 Boron
1 Caffeine
1 Caffeic Acid Phenethyl Ester (CAPE)
1 Sorafenib (brand name Nexavar)
1 Celastrol
1 chitosan
1 Chocolate
1 Choline
1 Chrysin
1 Hydroxycinnamic-acid
1 Aspirin -acetylsalicylic acid
1 Artemisinin
1 salinomycin
1 Deguelin
1 diet Fermented Foods
1 Bortezomib
1 diet Ketogenic
1 Disulfiram
1 Emodin
1 Electrical Pulses
1 Garcinol
1 hydroxychloroquine
1 mebendazole
1 nivolumab
1 Magnesium
1 Naringin
1 Noscapine
1 Piperlongumine
1 Quercetin
1 Radio Frequency
1 Shankhpushpi
1 Iron
1 Salvia miltiorrhiza
1 Tumor Treating Fields
1 Vitamin B1/Thiamine
1 Vitamin K2
1 Xylitol
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:229  State#:%  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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