GutMicro Cancer Research Results

GutMicro, Gut Microbiota: Click to Expand ⟱
Source:
Type:
Gut microbiome may affect responses to numerous forms of cancer therapy.
The gut microbiota plays a multifaceted role in cancer biology, influencing tumor development, progression, and patient prognosis. Dysbiosis and specific microbial populations have been linked to various cancers, with implications for patient outcomes. While the relationship between gut microbiota and cancer prognosis is an active area of research, it holds promise for the development of microbiome-based biomarkers and therapeutic strategies in oncology.


Scientific Papers found: Click to Expand⟱
6472- 1,8-Cin,    Protective Effects of 1,8-Cineole Microcapsules Against Inflammation and Gut Microbiota Imbalance Associated Weight Loss Induced by Heat Stress in Broiler Chicken
- in-vivo, Nor, NA
*Inflam↓, *GutMicro↑,
3538- 5-HTP,    Oral Administration of 5-Hydroxytryptophan Restores Gut Microbiota Dysbiosis in a Mouse Model of Depression
- in-vivo, Nor, NA
*GutMicro↑, *BBB↑, *5HT↑, *Weight↓,
1161- ACNs,  immuno,    Bilberry anthocyanin extracts enhance anti-PD-L1 efficiency by modulating gut microbiota
- in-vivo, Colon, MC38
GutMicro↑,
3972- ACNs,    Recent Research on the Health Benefits of Blueberries and Their Anthocyanins
- Review, AD, NA - Review, Park, NA
*cardioP↑, *neuroP↑, *Inflam↓, *antiOx↓, *GutMicro↑, *Half-Life↑, *LDL↓, *adiP↓, *HDL↑, *CRP↓, *IL1β↓, *Risk↓, *Risk↓, *cognitive↑, *memory↑, *other↑, *BOLD↑, *NO↓, *MDA↓, *GSH↑, *VitC↑, *SOD↑, *GPx↑, *eff↓, *eff↓, *eff↓, *eff↝, *Risk↓,
5351- Akk,    Akkermansia muciniphila supplementation in patients with overweight/obese type 2 diabetes: Efficacy depends on its baseline levels in the gut
- Human, Diabetic, NA
GutMicro↑, Weight↓,
540- Akk,    Akkermansia muciniphila: a potential booster to improve the effectiveness of cancer immunotherapy
- Analysis, NA, NA
GutMicro↑, carcinogenesis↓, ChemoSideEff↓,
541- Akk,    Akkermansia muciniphila as a Next-Generation Probiotic in Modulating Human Metabolic Homeostasis and Disease Progression: A Role Mediated by Gut-Liver-Brain Axes?
- Review, NA, NA
GutMicro↑, PD-1↝, CD8+↑, IL8↑,
4- Akk,    The Emerging Biotherapeutic Agent: Akkermansia
- Review, Var, NA
GutMicro↑,
2660- AL,    Allicin: A review of its important pharmacological activities
- Review, AD, NA - Review, Var, NA - Review, Park, NA - Review, Stroke, NA
*Inflam↓, AntiCan↑, *antiOx↑, *cardioP↑, *hepatoP↑, *BBB↑, *Half-Life↝, *H2S↑, *BP↓, *neuroP↑, *cognitive↑, *neuroP↑, *ROS↓, *GutMicro↑, *LDH↓, *ROS↓, *lipid-P↓, *antiOx↑, *other↑, *PI3K↓, *Akt↓, *NF-kB↓, *NO↓, *iNOS↓, *PGE2↓, *COX2↓, *IL6↓, *TNF-α↓, *MPO↓, *eff↑, *NRF2↑, *Keap1↓, *TBARS↓, *creat↓, *LDH↓, *AST↓, *ALAT↓, *MDA↓, *SOD↑, *GSH↑, *GSTs↑, *memory↑, chemoP↑, IL8↓, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, Casp12↑, p38↑, Fas↑, P53↑, P21↑, CHK1↓, CycB/CCNB1↓, GSH↓, ROS↑, TumCCA↑, Hif1a↓, Bcl-2↓, VEGF↓, TumCMig↓, STAT3↓, VEGFR2↓, p‑FAK↓,
2667- AL,    Allicin in Digestive System Cancer: From Biological Effects to Clinical Treatment
- Review, GC, NA
AntiCan↑, ChemoSen↑, angioG↓, chemoP↑, *GutMicro↑, *antiOx↑, other↝, GSH↓, Thiols↓, *ROS↓, *hepatoP↑, *Inflam↓, *NF-kB↓,
5356- AL,    Therapeutic role of allicin in gastrointestinal cancers: mechanisms and safety aspects
- Review, GC, NA
Apoptosis↑, TumCP↓, MAPK↓, PI3K↓, Akt↓, NF-kB↓, AntiCan↑, ChemoSen↑, TumCCA↑, Apoptosis↑, BioAv↑, selectivity↑, TGF-β↓, ROS↑, DNAdam↑, p‑P53↑, P21↑, cycD1/CCND1↓, cycE/CCNE↓, CDK4↓, CDK6↓, MMP↓, NF-kB↑, BAX↑, Bcl-2↓, ER Stress↑, Casp↑, AIF↑, Fas↑, Casp8↑, Cyt‑c↑, cl‑PARP↑, Ca+2↑, *NRF2↑, *chemoP↑, *GutMicro↑, CycB/CCNB1↑, H2S↑, HIF-1↓, RadioS↑,
3443- ALA,    Molecular and Therapeutic Insights of Alpha-Lipoic Acid as a Potential Molecule for Disease Prevention
- Review, Var, NA - Review, AD, NA
*antiOx↑, *ROS↓, *IronCh↑, *cognitive↑, *cardioP↓, AntiCan↑, *neuroP↑, *Inflam↓, *BioAv↓, *AntiAge↑, *Half-Life↓, *BioAv↝, other↝, EGFR↓, Akt↓, ROS↓, TumCCA↑, p27↑, PDH↑, Glycolysis↓, ROS↑, *eff↑, *memory↑, *motorD↑, *GutMicro↑,
5409- ASA,    Role of aspirin in cancer prevention
- Review, Var, NA
Imm↑, *Inflam↓, *AntiAg↑, *GutMicro↑, eff↑, TumMeta↓, angioG↓, Risk↓, Risk↓,
5421- ASTX,    Astaxanthin Inhibits PC-3 Xenograft Prostate Tumor Growth in Nude Mice
- in-vivo, Pca, NA
TumCG↑, Ki-67↑, PCNA↓, GutMicro↑, *Inflam↓, *cardioP↑, *ROS↓,
5424- ASTX,    Astaxanthin exerts an adjunctive anti-cancer effect through the modulation of gut microbiota and mucosal immunity
- in-vivo, Nor, NA
*GutMicro↑, AntiCan↑, eff↑, AntiTum↑, ChemoSen↑,
4982- ATV,    Inhibiting the mevalonate pathway with atorvastatin alters gut microbiota and has potential as an anti-cancer treatment for ovarian cancer
- in-vivo, Ovarian, NA
HMG-CoA↓, GutMicro↑,
5365- AV,    Aloe Vera Polysaccharides as Therapeutic Agents: Benefits Versus Side Effects in Biomedical Applications
- Review, Nor, NA - Review, IBD, NA - Review, Diabetic, NA
*Wound Healing↑, *Imm↑, *antiOx↑, *AntiDiabetic↑, *AntiCan↑, *Inflam↓, *NF-kB↓, *COX2↓, *5LO↓, *IL1β↓, *IL6↓, *TNF-α↓, *IL10↑, *other↓, *ROS↓, *SOD↑, *Catalase↑, *GPx↑, *lipid-P↓, *DNAdam↓, *GutMicro↑, *ZO-1↑, AntiTum↑, Casp3↑, Casp9↑, angioG↓, MMPs↓, VEGF↓, NK cell↑,
5571- B-Gluc,  immuno,    Potential benefit of β-glucans as adjuvant therapy in immuno-oncology: a review
- Review, Var, NA
Imm↑, ChemoSen↑, LDL↑, GutMicro↑, TumCP↓, Apoptosis↑, angioG↓, QoL↑,
5574- B-Gluc,    Beta Glucan: Health Benefits in Obesity and Metabolic Syndrome
- Review, Obesity, NA
*BioAv↑, *toxicity↓, *Imm↑, *eff↑, *Risk↓, *Weight↓, *eff↝, *BP↓, *GutMicro↑, *eff↓,
5577- B-Gluc,    Lentinan progress in inflammatory diseases and tumor diseases
- Review, Var, NA - Review, IBD, NA
AntiTum↑, GutMicro↑, *Inflam↓, *TNF-α↓, *NF-kB↓, ChemoSen↑, OS↑, Imm↑, IL6↓, ERK↓, MAPK↓, *antiOx↑, eff↑,
2769- Ba,  Rad,    Baicalein ameliorates ionizing radiation-induced injuries by rebalancing gut microbiota and inhibiting apoptosis
- in-vivo, Nor, NA
*radioP↑, GutMicro↑, *P53↓, *Apoptosis↑, *DR4↓,
2605- Ba,  BA,    Potential therapeutic effects of baicalin and baicalein
- Review, Var, NA - Review, Stroke, NA - Review, IBD, NA - Review, Arthritis, NA - Review, AD, NA - Review, Park, NA
cardioP↑, Inflam↓, cognitive↑, *hepatoP↑, *ROS?, *SOD↑, *GSH↑, *MMP↑, *GutMicro↑, ChemoSen↑, *TNF-α↓, *IL10↑, *IL6↓, *eff↑, *ROS↓, *COX2↓, *NF-kB↓, *STAT3↓, *PGE2↓, *MPO↓, *IL1β↓, *MMP2↓, *MMP9↓, *β-Amyloid↓, *neuroP↑, *Dose↝, *BioAv↝, *BioAv↝, *BBB↑, *BDNF↑,
2712- BBR,    Suppression of colon cancer growth by berberine mediated by the intestinal microbiota and the suppression of DNA methyltransferases (DNMTs)
- in-vitro, Colon, HT29 - in-vivo, NA, NA
TumCG↓, GutMicro↑, other↝, IL10↓, cMyc↓, DNMT1↓, DNMTs↓,
2713- BBR,    Berberine improved the microbiota in lung tissue of colon cancer and reversed the bronchial epithelial cell changes caused by cancer cells
- in-vitro, Nor, BEAS-2B
*GutMicro↑, *IL6↑, *IL10↑, *IL17↑, *IFN-γ↑, PDGF↓, *RAD51↓,
2678- BBR,    Berberine as a Potential Agent for the Treatment of Colorectal Cancer
- Review, CRC, NA
*Inflam↓, *antiOx↑, *cardioP↑, *neuroP↑, TumCCA↑, cycD1/CCND1↓, cycE/CCNE↓, CDC2↓, AMPK↝, mTOR↝, Casp8↑, Casp9↑, Cyt‑c↑, TumCMig↓, TumCI↓, EMT↓, MMPs↓, E-cadherin↓, Telomerase↓, *toxicity↓, GRP78/BiP↓, EGFR↓, CDK4↓, COX2↓, PGE2↓, p‑JAK2↓, p‑STAT3↓, MMP2↓, MMP9↓, GutMicro↑, eff↝, *BioAv↓, BioAv↑,
5621- Bif,  immuno,    Commensal Bifidobacterium promotes antitumor immunity and facilitates anti–PD-L1 efficacy
TumCG↓, GutMicro↑,
5623- Bif,    Bifidobacterium breve predicts the efficacy of anti-PD-1 immunotherapy combined with chemotherapy in Chinese NSCLC patients
- Study, NSCLC, NA
GutMicro↑, OS↑, eff↑,
5628- Bif,  immuno,    Bifidobacterium modulation of tumor immunotherapy and its mechanism
- Review, Var, NA
Imm↑, Risk↓, GutMicro↑, AntiTum↑, OS↑, selectivity↑, eff↑,
5629- Bif,  ProBio,    Gut microbiota shapes cancer immunotherapy responses
- Review, Var, NA
eff↑, DCells↑, CD8+↑, eff↑, AntiTum↑, other↑, selectivity↑, GutMicro↑,
752- Bor,    The Potential Role of Boron in the Modulation of Gut Microbiota Composition: An In Vivo Pilot Study
GutMicro↑,
2776- Bos,    Anti-inflammatory and anti-cancer activities of frankincense: Targets, treatments and toxicities
- Review, Var, NA
*5LO↓, *TNF-α↓, *MMP3↓, *COX1↓, *COX2↓, *PGE2↓, *Th2↑, *Catalase↑, *SOD↑, *NO↑, *PGE2↑, *IL1β↓, *IL6↓, *Th1 response↓, *Th2↑, *iNOS↓, *NO↓, *p‑JNK↓, *p38↓, GutMicro↑, p‑Akt↓, GSK‐3β↓, cycD1/CCND1↓, Akt↓, STAT3↓, CSCs↓, AR↓, P21↑, DR5↑, CHOP↑, Casp3↑, Casp8↑, cl‑PARP↑, DNAdam↑, p‑RB1↓, FOXM1↓, TOP2↓, CDC25↓, p‑CDK1↓, p‑ERK↓, MMP9↓, VEGF↓, angioG↓, ROS↑, Cyt‑c↑, AIF↑, Diablo↑, survivin↓, ICAD↓, ChemoSen↑, SOX9↓, ER Stress↑, GRP78/BiP↑, cal2↓, AMPK↓, mTOR↓, ROS↓,
5711- Brut,    Citrus bergamia powder: Antioxidant, antimicrobial and anti-inflammatory properties
- in-vitro, Nor, HMEC
*antiOx↑, *Bacteria↓, *GutMicro↑,
5744- Buty,  PacT,    Oral sodium butyrate supplementation ameliorates paclitaxel-induced behavioral and intestinal dysfunction
- in-vivo, Var, NA
chemoP↑, neuroP↑, Inflam↓, GutMicro↑, *ROS↓, Dose↝,
5743- Buty,    Regulation of Intestinal Butyrate Transporters by Oxidative and Inflammatory Status
- Review, Var, NA
*GutMicro↑, *other↑, *Inflam↓, *ROS↓, AntiCan↑, HCAR2↑, HDAC↓,
5739- Buty,    Butyrate as a promising therapeutic target in cancer: From pathogenesis to clinic (Review)
- Review, Var, NA
GutMicro↑, *Inflam↓, *IL6↓, *TNF-α↓, *IL17↓, *IL10↑, *ROS↝, COX2↓, NLRP3↓, Imm↑, HDAC↓, TumCCA↑, Apoptosis↑, ROS↑, Casp↑, mtDam↑, Cyt‑c↑, eff↑, chemoP↑, ChemoSen↑, eff↑, RadioS↑, HCAR2↑,
5738- Buty,    Butyrate’s role in human health and the current progress towards its clinical application to treat gastrointestinal disease
- Review, Nor, NA
*GutMicro↑, *Risk↓,
5735- Buty,    Butyrate and the Intestinal Epithelium: Modulation of Proliferation and Inflammation in Homeostasis and Disease
- Study, Nor, NA
*Inflam↓, GutMicro↑, Imm↑,
5733- Buty,  VitB3,    Activation of Gpr109a, Receptor for Niacin and the Commensal Metabolite Butyrate, Suppresses Colonic Inflammation and Carcinogenesis
- in-vivo, CRC, NA
GutMicro↑, HCAR2↑, AntiCan↑, Inflam↓, IL18↑,
5732- Buty,    GPR109A is a G-protein-coupled receptor for the bacterial fermentation product butyrate and functions as a tumor suppressor in colon
- Study, CRC, NA
HCAR2↑, other↓, Apoptosis↑, HDAC↓, Bcl-2↓, Bcl-xL↓, cycD1/CCND1↓, DR5↑, NF-kB↓, GutMicro↑, SLC12A5↝,
1032- Buty,    Gut microbiome-derived butyrate inhibits the immunosuppressive factors PD-L1 and IL-10 in tumor-associated macrophages in gastric cancer
- in-vivo, GC, AGS
GutMicro↑, PD-L1↓, IL10↓, TumCG↓,
5859- CAP,    Are We Ready to Recommend Capsaicin for Disorders Other Than Neuropathic Pain?
- Review, Var, NA
*TRPV1↑, *Ca+2↑, *Na+↑, *UCPs↑, *SIRT1↑, *PPARγ↑, *Inflam↓, *lipid-P↑, *IL6↓, *TNF-α↓, *NF-kB↓, *p‑Akt↑, *NRF2↑, *HO-1↑, *ROS↑, *GutMicro↑,
5858- CAP,    Capsaicin as a Microbiome Modulator: Metabolic Interactions and Implications for Host Health
- Review, Nor, NA - Review, AD, NA
*BBB↓, *GutMicro↑, Obesity↓, *Inflam↓, *AntiCan↑, *TRPV1↑, *Ca+2↑, *antiOx↑, *cardioP↑, *BioAv↓, *Half-Life↓, *BioAv↝, *BioAv↑, *neuroP↑, Apoptosis↑, p38↑, ROS↑, MMP↓, MPT↑, Cyt‑c↑, Casp↑, TRIB3↑, NADH↓, SIRT1↓, TumCG↓, TumCMig↓, TOP1↓, TOP2↓, β-catenin/ZEB1↓, *ROS↓, *Aβ↓,
5933- CAR,    Protective Effect of Carvacrol against Gut Dysbiosis and Clostridium difficile Associated Disease in a Mouse Model
- in-vivo, IBD, NA
*Diar↓, *GutMicro↑, *Dysb↓,
5932- CAR,    Carvacrol attenuates mucosal barrier impairment and tumorigenesis by regulating gut microbiome
- in-vivo, IBD, NA - in-vivo, Park, NA
*GutMicro↑, Risk↓, *Inflam↓, *antiOx↓, *ZO-1↑, *iNOS↓, *IL6↓, *NO↓, *PGE2↓, *memory↑, *TLR4↓, *NF-kB↓, *IBI↑, *CLDN3↑, *CLDN1↑, *MUC1↑, *OCLN↑, *iNOS↑, *COX2↓, *IFN-γ↓, IL1β↓, ADAM10?,
6650- Cen,    Therapeutic Potential of Centella asiatica and Its Triterpenes: A Review
- Review, AD, NA
*BioAv↝, *BioAv↝, *MDA↓, *GSH↑, *SOD↑, *AChE↓, *memory↑, *Ki-67↑, *Catalase↑, *PI3K↑, *BDNF↑, *NGF↑, *ROS↓, *NRF2↑, *HO-1↑, *NQO1↑, *ATP↑, *OCR↑, *TNF-α↓, *PP2A↑, *GSK‐3β↓, *Bcl-2↑, *TrkB↑, *NOTCH1↑, *SOX2↑, *Nestin↑, *MDA↓, *MAOA↓, *MAOB↓, *GPx↑, *cognitive↑, *ROS↓, *neuroP↑, *glucose↓, *ALAT↓, *AST↓, *PFK↓, *Weight↓, *Inflam↓, *AntiDiabetic↑, *Obesity↓, *Wound Healing↑, *cardioP↑, *GutMicro↑, *Sepsis↓, *BioAv↑,
6022- CGA,    Chlorogenic Acid: Recent Advances on Its Dual Role as a Food Additive and a Nutraceutical against Metabolic Syndrome
- Review, Nor, NA
*antiOx↑, *Inflam↓, *AntiDiabetic↑, *Obesity↓, *Wound Healing↑, *BP↓, *Dose↝, *ROS↓, *Fas↓, *HMG-CoA↓, *GutMicro↑,
6016- CGA,    Coffee Chlorogenic Acids Incorporation for Bioactivity Enhancement of Foods: A Review
- Review, Var, NA - Review, AD, NA - Review, Diabetic, NA
antiOx↑, *Bacteria↓, AntiCan↑, *Inflam↓, *cardioP↑, *AntiDiabetic↑, *GutMicro↑, *eff↑, *eff↑, *ROS↓, *IronCh↑, *neuroP↑, *AChE↓, *BChE↓, *chemoPv↑, *BioAv⇅,
6011- CGA,    Chlorogenic Acid’s Role in Metabolic Health: Mechanisms and Therapeutic Potential
- Review, Nor, NA
*BioAv↓, *antiOx↑, *Inflam↓, *Bacteria↓, *hepatoP↑, *cardioP↑, *neuroP↑, *ROS↓, *NF-kB↓, *NRF2↑, *Obesity↓, *GutMicro↑, *AntiAg↑, *cardioP↑, *AntiDiabetic↑, *NLRP3↓, *OCLN↓, *VEGF↓, BioAv↝,
6045- CGA,  SeNPs,    A Flower-like Brain Targeted Selenium Nanocluster Lowers the Chlorogenic Acid Dose for Ameliorating Cognitive Impairment in APP/PS1 Mice
- in-vivo, AD, NA
*neuroP↑, *BioAv↑, *GutMicro↑, *BBB↑, *Aβ↓, *glucose↝,
6023- CGA,    Pharmacological advances of the chlorogenic acids family: current insights and future research directions
- Review, AD, NA - Review, Park, NA - Review, IBD, NA
*Aβ↓, *neuroP↑, *cardioP↑, *GastroP↑, *RenoP↑, *hepatoP↑, *Obesity↓, *Bacteria↓, *BioAv↑, *BioAv↑, *BioAv↑, *ROS↓, *GutMicro↑, *IBI↑, *MCT1↓, *NF-kB↓, *DNMT1↓,

Showing Research Papers: 1 to 50 of 135
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 135

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   GSH↓, 2,   NADH↓, 1,   ROS↓, 2,   ROS↑, 6,   Thiols↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↑, 2,   CDC2↓, 1,   CDC25↓, 1,   MMP↓, 2,   MPT↑, 1,   mtDam↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AMPK↓, 1,   AMPK↝, 1,   cMyc↓, 1,   Glycolysis↓, 1,   H2S↑, 1,   HMG-CoA↓, 1,   LDL↑, 1,   PDH↑, 1,   SIRT1↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 3,   p‑Akt↓, 1,   Apoptosis↑, 6,   BAX↑, 1,   Bcl-2↓, 3,   Bcl-xL↓, 1,   Casp↑, 3,   Casp12↑, 1,   Casp3↑, 3,   Casp8↑, 4,   Casp9↑, 3,   Cyt‑c↑, 6,   Diablo↑, 1,   DR5↑, 2,   Fas↑, 2,   ICAD↓, 1,   MAPK↓, 2,   p27↑, 1,   p38↑, 2,   survivin↓, 1,   Telomerase↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

HCAR2↑, 4,   SOX9↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

carcinogenesis↓, 1,   other↓, 1,   other↑, 1,   other↝, 3,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP↑, 1,   ER Stress↑, 2,   GRP78/BiP↓, 1,   GRP78/BiP↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

CHK1↓, 1,   DNAdam↑, 2,   DNMT1↓, 1,   DNMTs↓, 1,   P53↑, 1,   p‑P53↑, 1,   cl‑PARP↑, 2,   PCNA↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

p‑CDK1↓, 1,   CDK4↓, 2,   CycB/CCNB1↓, 1,   CycB/CCNB1↑, 1,   cycD1/CCND1↓, 4,   cycE/CCNE↓, 2,   P21↑, 3,   p‑RB1↓, 1,   TumCCA↑, 5,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CSCs↓, 1,   EMT↓, 1,   ERK↓, 1,   p‑ERK↓, 1,   FOXM1↓, 1,   GSK‐3β↓, 1,   HDAC↓, 3,   mTOR↓, 1,   mTOR↝, 1,   PI3K↓, 1,   STAT3↓, 2,   p‑STAT3↓, 1,   TOP1↓, 1,   TOP2↓, 2,   TumCG↓, 4,   TumCG↑, 1,  

Migration(tgid=13) ⓘ

Ca+2↑, 1,   cal2↓, 1,   E-cadherin↓, 1,   p‑FAK↓, 1,   Ki-67↑, 1,   MMP2↓, 1,   MMP9↓, 2,   MMPs↓, 2,   PDGF↓, 1,   TGF-β↓, 1,   TRIB3↑, 1,   TumCI↓, 1,   TumCMig↓, 3,   TumCP↓, 2,   TumMeta↓, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 5,   EGFR↓, 2,   HIF-1↓, 1,   Hif1a↓, 1,   VEGF↓, 3,   VEGFR2↓, 1,  

Barriers & Transport(tgid=15) ⓘ

SLC12A5↝, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2↓, 2,   DCells↑, 1,   HCAR2↑, 4,   IL10↓, 2,   IL18↑, 1,   IL1β↓, 1,   IL6↓, 1,   IL8↓, 1,   IL8↑, 1,   Imm↑, 6,   Inflam↓, 3,   p‑JAK2↓, 1,   NF-kB↓, 2,   NF-kB↑, 1,   NK cell↑, 1,   PD-1↝, 1,   PD-L1↓, 1,   PGE2↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

ADAM10?, 1,  

Protein Aggregation(tgid=19) ⓘ

NLRP3↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 1,   CDK6↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 2,   BioAv↝, 1,   ChemoSen↑, 8,   Dose↝, 1,   eff↑, 9,   eff↝, 1,   RadioS↑, 2,   selectivity↑, 3,  

Clinical Biomarkers(tgid=22) ⓘ

AR↓, 1,   EGFR↓, 2,   FOXM1↓, 1,   GutMicro↑, 24,   IL6↓, 1,   Ki-67↑, 1,   PD-L1↓, 1,   TRIB3↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 8,   AntiTum↑, 5,   cardioP↑, 1,   chemoP↑, 4,   ChemoSideEff↓, 1,   cognitive↑, 1,   neuroP↑, 1,   Obesity↓, 1,   OS↑, 3,   QoL↑, 1,   Risk↓, 4,   Weight↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

CD8+↑, 2,  
Total Targets: 159

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

Dysb↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 2,   antiOx↑, 11,   Catalase↑, 3,   GPx↑, 3,   GSH↑, 4,   GSTs↑, 1,   HDL↑, 1,   HO-1↑, 2,   Keap1↓, 1,   lipid-P↓, 2,   lipid-P↑, 1,   MDA↓, 4,   MPO↓, 2,   NQO1↑, 1,   NRF2↑, 5,   ROS?, 1,   ROS↓, 16,   ROS↑, 1,   ROS↝, 1,   SOD↑, 6,   TBARS↓, 1,   UCPs↑, 1,   VitC↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 2,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↑, 1,   MMP↑, 1,   OCR↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

adiP↓, 1,   ALAT↓, 2,   glucose↓, 1,   glucose↝, 1,   H2S↑, 1,   HMG-CoA↓, 1,   LDH↓, 2,   LDL↓, 1,   PFK↓, 1,   PPARγ↑, 1,   SIRT1↑, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   p‑Akt↑, 1,   Apoptosis↑, 1,   Bcl-2↑, 1,   DR4↓, 1,   Fas↓, 1,   iNOS↓, 3,   iNOS↑, 1,   p‑JNK↓, 1,   MCT1↓, 1,   p38↓, 1,   TRPV1↑, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

other↓, 1,   other↑, 3,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,   DNMT1↓, 1,   P53↓, 1,   RAD51↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

GSK‐3β↓, 1,   Nestin↑, 1,   NOTCH1↑, 1,   PI3K↓, 1,   PI3K↑, 1,   SOX2↑, 1,   STAT3↓, 1,  

Migration(tgid=13) ⓘ

5LO↓, 2,   AntiAg↑, 2,   Ca+2↑, 2,   CLDN1↑, 1,   Ki-67↑, 1,   MMP2↓, 1,   MMP3↓, 1,   MMP9↓, 1,   MUC1↑, 1,   Na+↑, 1,   ZO-1↑, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

NO↓, 4,   NO↑, 1,   VEGF↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 1,   BBB↑, 4,   CLDN3↑, 1,   GastroP↑, 1,   IBI↑, 2,   Na+↑, 1,   OCLN↓, 1,   OCLN↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX1↓, 1,   COX2↓, 5,   CRP↓, 1,   IFN-γ↓, 1,   IFN-γ↑, 1,   IL10↑, 4,   IL17↓, 1,   IL17↑, 1,   IL1β↓, 4,   IL6↓, 7,   IL6↑, 1,   Imm↑, 2,   Inflam↓, 20,   NF-kB↓, 9,   PGE2↓, 4,   PGE2↑, 1,   Th1 response↓, 1,   Th2↑, 2,   TLR4↓, 1,   TNF-α↓, 8,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 1,   AChE↓, 2,   BChE↓, 1,   BDNF↑, 2,   MAOA↓, 1,   NGF↑, 1,   TrkB↑, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 3,   MAOB↓, 1,   NLRP3↓, 1,   PP2A↑, 1,   β-Amyloid↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 4,   BioAv↑, 7,   BioAv⇅, 1,   BioAv↝, 6,   Dose↝, 2,   eff↓, 4,   eff↑, 6,   eff↝, 2,   Half-Life↓, 2,   Half-Life↑, 1,   Half-Life↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 2,   AST↓, 2,   BP↓, 3,   creat↓, 1,   CRP↓, 1,   GutMicro↑, 26,   IL6↓, 7,   IL6↑, 1,   Ki-67↑, 1,   LDH↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↑, 2,   AntiDiabetic↑, 5,   BOLD↑, 1,   cardioP↓, 1,   cardioP↑, 10,   chemoP↑, 1,   chemoPv↑, 1,   cognitive↑, 4,   hepatoP↑, 5,   memory↑, 5,   motorD↑, 1,   neuroP↑, 12,   Obesity↓, 4,   radioP↑, 1,   RenoP↑, 1,   Risk↓, 5,   toxicity↓, 2,   Weight↓, 3,   Wound Healing↑, 3,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 4,   Diar↓, 1,   Sepsis↓, 1,  
Total Targets: 162

Scientific Paper Hit Count for: GutMicro, Gut Microbiota
8 Butyrate
8 Selenium NanoParticles
7 immunotherapy
6 Urolithin
5 Chlorogenic acid
5 diet Fermented Foods
4 Akkermansia
4 Bifidobacterium
4 probiotics
4 Cinnamon
4 Curcumin
4 diet FMD Fasting Mimicking Diet
4 Rosmarinic acid
4 Selenite (Sodium)
3 Allicin (mainly Garlic)
3 beta-glucans
3 Berberine
3 Carvacrol
3 Ferulic acid
3 Hydrogen Gas
3 Pterostilbene
2 Anthocyanins
2 Astaxanthin
2 Baicalein
2 Vitamin B3,Niacin
2 Capsaicin
2 chitosan
2 Date Fruit Extract
2 Chemotherapy
2 Luteolin
2 Phenylbutyrate
2 Resveratrol
2 Taurine
2 Thymol-Thymus vulgaris
1 1,8-Cineole
1 5-Hydroxytryptophan
1 Alpha-Lipoic-Acid
1 Aspirin
1 Atorvastatin
1 Aloe anthraquinones
1 Radiotherapy/Radiation
1 Baicalin
1 Boron
1 Boswellia (frankincense)
1 Bruteridin(bergamot juice)
1 Paclitaxel
1 Centella asiatica / Gotu kola → asiaticoside
1 Prebiotic
1 Chlorophyllin
1 Chocolate
1 Calorie Restriction Mimetics
1 diet Methionine-Restricted Diet
1 Dandelion Root
1 Eugenol
1 Fucoidan
1 Shilajit/Fulvic Acid
1 Gallic acid
1 Lecithin
1 Lycopene
1 Magnolol
1 Magnetic Fields
1 nicotinamide adenine dinucleotide
1 Naringin
1 Nimbolide
1 Quercetin
1 Sulforaphane (mainly Broccoli)
1 Silymarin (Milk Thistle) silibinin
1 Shikonin
1 Aflavin-3,3′-digallate
1 Thyme
1 Turmerones
1 Ursolic acid
1 Vitamin D3
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:350  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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