HemoG Cancer Research Results

HemoG, Hemoglobin: Click to Expand ⟱
Source:
Type:
Hemoglobin (often abbreviated as "HemoG") is a protein in red blood cells responsible for transporting oxygen throughout the body. While hemoglobin itself is not directly linked to cancer, there are several important aspects of its relationship with cancer that are worth noting:
Many cancer patients experience anemia, which is a condition characterized by low levels of hemoglobin. This can be due to various factors, including the cancer itself, chemotherapy, or nutritional deficiencies.
Tumors often have regions of low oxygen (hypoxia) due to inadequate blood supply. Hypoxia can promote tumor progression, metastasis, and resistance to therapy. Hemoglobin's role in oxygen transport makes it a critical factor in the tumor microenvironment, as oxygen levels can influence cancer cell behavior.
Changes in hemoglobin levels or the presence of specific hemoglobin variants may serve as potential biomarkers for certain cancers.
Scientific Papers found: Click to Expand⟱
6954- FA,    Folic acid as a potential therapeutic agent for Alzheimer's disease: Effects on inflammatory cytokines, amyloid deposition, and neurotransmitter metabolism
- Trial, AD, NA
*Inflam↓, FA supplementation can effectively delay AD progression by inhibiting neuroinflammation, reducing amyloid deposition, regulating neurotransmitter metabolism and improving nutritional status.
*Aβ↓,
*IL1β↓, levels of inflammatory factors (IL-1b, IL-6, and TNF-a), Ab1-42, and Tau were significantly lower (P<0.05), and neurotransmitters (GABA, 5-HT, and Ach) and nutritional indexes (albumin and hemoglobin) were substantially higher.
*IL6↓,
*TNF-α↓,
*tau↓,
*GABA↑,
*5HT↑,
*Ach↑,
*Albumin↑,
*HemoG↑,
*neuroP↑, GABA, 5-HT, and Ach in both groups increased after treatment, with more significant increases in the experimental group (P<0.001), indicating better neurological function
*Hcy/homoC↓, FA supplementation has been shown to effectively promote plasma conversion of Hcy to reduce plasma Hcy concentrations in patients with metabolic syndrome

7640- IP6,  Ins,    Effects of Inositol Hexaphosphate and Myo-Inositol Administration in Breast Cancer Patients during Adjuvant Chemotherapy
- Trial, BC, NA
*antiOx↑, Inositol hexaphosphate (IP6) is known as a strong antioxidant agent, able to improve local (i.e., breast region) side effects, functional status and quality-of-life.
QoL↑,
RBC↑, The Inositol Group showed a lower decrease in red blood cells, hemoglobin levels and white blood cells with respect to controls
HemoG↑,
WBC↑,
chemoP↑, , as well as amelioration in scores related to breast and arm local symptoms (p ≤ 0.02), body image (p = 0.04) and quality-of-life related symptoms
Dose↝, BC patients enrolled in the Inositol Group received topical gel containing 5 g of 4% IP6 and capsules containing 390 mg of myo-inositol


Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

RBC↑, 1,   WBC↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

HemoG↑, 1,  

Functional Outcomes(tgid=23) ⓘ

chemoP↑, 1,   QoL↑, 1,  
Total Targets: 6

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

Ach↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

IL1β↓, 1,   IL6↓, 1,   Inflam↓, 1,   TNF-α↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 1,   GABA↑, 1,   tau↓, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 1,  

Clinical Biomarkers(tgid=22) ⓘ

Albumin↑, 1,   Hcy/homoC↓, 1,   HemoG↑, 1,   IL6↓, 1,  

Functional Outcomes(tgid=23) ⓘ

neuroP↑, 1,  
Total Targets: 15

Scientific Paper Hit Count for: HemoG, Hemoglobin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:487  State#:%  Dir#:2
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