SOX2 Cancer Research Results

SOX2, SOX2: Click to Expand ⟱

Source:

Type:

SOX2 is a transcription factor that plays a crucial role in the development and maintenance of various cell types, including stem cells and progenitor cells. In the context of cancer, SOX2 has been found to be overexpressed in several types of tumors, including lung, breast, and esophageal cancers.
Overexpressed in: Lung, Breast, Esophageal, Prostate, GBM, CRC.

Scientific Papers found: Click to Expand⟱

4258-

CoQ10,

Neuroprotective effects of coenzyme Q10-loaded exosomes obtained from adipose-derived stem cells in a rat model of Alzheimer's disease

in-vivo,

AD,

Rat model

*memory↑, Exo+CoQ10 significantly improved STZ-induced memory impairment compared to CoQ10 and Exo groups alone.
*BDNF↑, BDNF expression increased in the STZ-induced rats after Exo+ CoQ10, when compared to the CoQ10 and Exo groups.
*cognitive↑, this study, Exo+ COQ10 enhanced cognition and memory deficiency in Alzheimer's disease by boosting BDNF and SOX2 levels in the hippocampus.
*SOX2↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Total Targets: 0

Pathway results for Effect on Normal Cells:

Proliferation, Differentiation & Cell State ⓘ

SOX2↑, 1,

Synaptic & Neurotransmission ⓘ

BDNF↑, 1,

Functional Outcomes ⓘ

cognitive↑, 1, memory↑, 1,
Total Targets: 4

Scientific Paper Hit Count for: SOX2, SOX2

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells