EGF Cancer Research Results

EGF, Epidermal Growth Factor expression: Click to Expand ⟱
Source:
Type:
EGF is a protein that acts as a ligand, binding to its receptor, EGFR. It is a potent mitogen, stimulating cell proliferation and differentiation. EGF is involved in various physiological processes, including wound healing, embryonic development, and tissue regeneration. EGF is overexpressed: breast, CRC, GBM, lung, ovarian.
EGF is decreased: Prostate, Pancreatic.
Scientific Papers found: Click to Expand⟱
452- CUR,    Curcumin downregulates the PI3K-AKT-mTOR pathway and inhibits growth and progression in head and neck cancer cells
- vitro+vivo, HNSCC, SCC9 - vitro+vivo, HNSCC, FaDu - vitro+vivo, HNSCC, HaCaT
TumCCA↑, PI3k/Akt/mTOR↓, Casp3↑, EGFR↓, EGF↑, PRKCG↑, p‑Akt↓, p‑mTOR↓, RPS6KA1↓, EIF4E↓, proCasp3↓,
2527- H2,    The healing effect of hydrogen-rich water on acute radiation-induced skin injury in rats
- in-vivo, Wounds, NA
*Dose↝, *SOD↑, *EGF↑, *antiOx↑, *Inflam↓, *Dose↝,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Mitochondria & Bioenergetics ⓘ

EGF↑, 1,  

Core Metabolism/Glycolysis ⓘ

PI3k/Akt/mTOR↓, 1,  

Cell Death ⓘ

p‑Akt↓, 1,   Casp3↑, 1,   proCasp3↓, 1,  

Cell Cycle & Senescence ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

EIF4E↓, 1,   p‑mTOR↓, 1,   PRKCG↑, 1,   RPS6KA1↓, 1,  

Angiogenesis & Vasculature ⓘ

EGFR↓, 1,  

Clinical Biomarkers ⓘ

EGFR↓, 1,  
Total Targets: 12

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 1,   SOD↑, 1,  

Mitochondria & Bioenergetics ⓘ

EGF↑, 1,  

Immune & Inflammatory Signaling ⓘ

Inflam↓, 1,  

Drug Metabolism & Resistance ⓘ

Dose↝, 2,  
Total Targets: 5

Scientific Paper Hit Count for: EGF, Epidermal Growth Factor expression
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:713  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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