OCN Cancer Research Results

OCN, Osteocalcin: Click to Expand ⟱
Source:
Type: protein
OCN (Osteocalcin) is a protein that is primarily produced by osteoblasts and plays a crucial role in bone mineralization and calcium ion homeostasis.
OCN is overexpressed in: breast, lung, osteosarcoma cancers.
Scientific Papers found: Click to Expand⟱
530- MF,    Low frequency sinusoidal electromagnetic fields promote the osteogenic differentiation of rat bone marrow mesenchymal stem cells by modulating miR-34b-5p/STAC2
- in-vivo, Nor, NA
*miR-34b-5p↓, *ALP↑, *RUNX2↑, *BMP2↑, *OCN↑, *OPN↑, *β-catenin/ZEB1↑, *STAC2↑, *Diff↑, *BMD↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Cell Death ⓘ

BMP2↑, 1,  

Kinase & Signal Transduction ⓘ

OCN↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

Diff↑, 1,   RUNX2↑, 1,  

Migration ⓘ

OPN↑, 1,   STAC2↑, 1,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature ⓘ

miR-34b-5p↓, 1,  

Clinical Biomarkers ⓘ

ALP↑, 1,   BMD↑, 1,  
Total Targets: 10

Scientific Paper Hit Count for: OCN, Osteocalcin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:778  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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