AMP Cancer Research Results

AMP, Adenosine Monophosphate: Click to Expand ⟱
Source:
Type: nucleotide
AMP (Adenosine Monophosphate) is a nucleotide that plays a crucial role in various cellular processes, including energy metabolism, cell growth, and differentiation,
AMP is a key energy currency in cells, serving as a intermediate in the production of ATP (Adenosine Triphosphate) from ADP (Adenosine Diphosphate).
AMP expression associated with Tumor growth, angiogensis, metastasis
Scientific Papers found: Click to Expand⟱
2879- HNK,    Honokiol Inhibits Lung Tumorigenesis through Inhibition of Mitochondrial Function
- in-vitro, Lung, H226 - in-vivo, NA, NA
tumCV↓, selectivity↑, TumCP↓, TumCCA↑, Apoptosis↑, mt-ROS↑, Casp3↑, Casp7↑, OCR↓, Cyt‑c↑, ATP↓, mitResp↓, AMP↑, AMPK↑,
5800- MET,    Metformin as anticancer agent and adjuvant in cancer combination therapy: Current progress and future prospect
- Review, Var, NA
ChemoSen↑, RadioS↑, Imm↑, *AntiDiabetic↑, *AMPK↑, TumCP↓, hepatoP↑, ATP↓, AMP↑, glucoNG↓, ROS↑, compI↓, DNAdam↑, CSCs↓, NP/CIPN↓, chemoP↑, toxicity↓, Trx↓, eff↑, cycD1/CCND1↓, CDK4↓, CDK6↓, cycE/CCNE↓, CDK2↓,
5609- NaHCO3,    Alkalization of cellular pH leads to cancer cell death by disrupting autophagy and mitochondrial function
- in-vitro, Var, NA
eff↑, e-pH↑, MMP↓, OXPHOS↝, AMP↑, TumAuto↑, MPT↑, mtDam↑,

Showing Research Papers: 1 to 3 of 3

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

compI↓, 1,   OXPHOS↝, 1,   ROS↑, 1,   mt-ROS↑, 1,   Trx↓, 1,  

Mitochondria & Bioenergetics ⓘ

ATP↓, 2,   mitResp↓, 1,   MMP↓, 1,   MPT↑, 1,   mtDam↑, 1,   OCR↓, 1,  

Core Metabolism/Glycolysis ⓘ

AMP↑, 3,   AMPK↑, 1,   glucoNG↓, 1,  

Cell Death ⓘ

Apoptosis↑, 1,   Casp3↑, 1,   Casp7↑, 1,   Cyt‑c↑, 1,  

Transcription & Epigenetics ⓘ

tumCV↓, 1,  

Autophagy & Lysosomes ⓘ

TumAuto↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↑, 1,  

Cell Cycle & Senescence ⓘ

CDK2↓, 1,   CDK4↓, 1,   cycD1/CCND1↓, 1,   cycE/CCNE↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

CSCs↓, 1,  

Migration ⓘ

TumCP↓, 2,  

Immune & Inflammatory Signaling ⓘ

Imm↑, 1,  

Cellular Microenvironment ⓘ

e-pH↑, 1,  

Hormonal & Nuclear Receptors ⓘ

CDK6↓, 1,  

Drug Metabolism & Resistance ⓘ

ChemoSen↑, 1,   eff↑, 2,   RadioS↑, 1,   selectivity↑, 1,  

Functional Outcomes ⓘ

chemoP↑, 1,   hepatoP↑, 1,   NP/CIPN↓, 1,   toxicity↓, 1,  
Total Targets: 39

Pathway results for Effect on Normal Cells:


Core Metabolism/Glycolysis ⓘ

AMPK↑, 1,  

Functional Outcomes ⓘ

AntiDiabetic↑, 1,  
Total Targets: 2

Scientific Paper Hit Count for: AMP, Adenosine Monophosphate
1 Honokiol
1 Metformin
1 Bicarbonate(Sodium)
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:794  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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