miR-141 Cancer Research Results

miR-141, miR-141: Click to Expand ⟱
Source:
Type:
miR-141 is a member of the microRNA-200 family, which is involved in the regulation of various cellular processes including proliferation, differentiation, apoptosis, and epithelial-to-mesenchymal transition (EMT). As a non-coding RNA, miR-141 regulates gene expression at the post-transcriptional level by binding to specific target messenger RNAs (mRNAs).

miR-141 plays a role in the regulation of EMT by targeting key transcription factors or other EMT-related genes. Its regulation can thus indirectly influence cell adhesion, migration, and invasion.

Both upregulation and downregulation of miR-141 have been reported, with its expression pattern often being context-dependent and linked to the stage and molecular subtype of the tumor.
Scientific Papers found: Click to Expand⟱
4707- CUR,    The Potential Role of Curcumin as a Regulator of microRNA in Colorectal Cancer: A Systematic Review
- Review, Var, NA
miR-497↑, Curcumin was found to cause the upregulation of miR-497, miR-200c, miR-200b, miR-409-3p, miR‐34, miR‐126, miR-145, miR-206, miR-491, miR-141, miR-429, miR-101, and miR-15a
miR-200c↑,
miR-409-3p↑,
miR-34a↑,
miR-126↑,
miR-145↑,
miR-206↑,
miR-491↑,
miR-141↑,
miR-429↑,
miR-101↑,
miR-15↑,
miR-21↓, and the downregulation of miR-21, miR-155, miR‐221, miR‐222, miR-17-5p, miR-130a, miR-27, and miR-20a.
miR-155↓,
miR-221↓,
miR‐222↓,
miR-17↓,
miR-130a↓,
miR-27a-3p↓,
miR-20↓,

1120- HNK,    Honokiol suppresses renal cancer cells' metastasis via dual-blocking epithelial-mesenchymal transition and cancer stem cell properties through modulating miR-141/ZEB2 signaling
- vitro+vivo, RCC, NA
EMT↓,
CSCs↓, cancer stem cell (CSC) properties
TumCG↓,
miR-141↑,


Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death ⓘ

miR-497↑, 1,  

Transcription & Epigenetics ⓘ

miR-145↑, 1,   miR-21↓, 1,   miR-27a-3p↓, 1,   miR-409-3p↑, 1,  

Proliferation, Differentiation & Cell State ⓘ

CSCs↓, 1,   EMT↓, 1,   miR-101↑, 1,   miR-34a↑, 1,   miR-429↑, 1,   TumCG↓, 1,  

Migration ⓘ

miR-130a↓, 1,   miR-141↑, 2,   miR-155↓, 1,   miR-20↓, 1,   miR-200c↑, 1,   miR-206↑, 1,   miR-221↓, 1,   miR-491↑, 1,   miR‐222↓, 1,  

Angiogenesis & Vasculature ⓘ

miR-126↑, 1,   miR-15↑, 1,   miR-17↓, 1,  
Total Targets: 23

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: miR-141, miR-141
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:816  State#:%  Dir#:2
  wNotes=on  sortOrder:rid,rpid

 

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