AntiCan Cancer Research Results

AntiCan, Anticancer Effect: Click to Expand ⟱
Source:
Type: general indicator
Anticancer Effect


Scientific Papers found: Click to Expand⟱
7632- Ins,    The paradoxical role of inositol in cancer: a consequence of the metabolic state of a tumor
- Review, Var, NA
AMPK↑, mechanism by which inositol may suppress tumor cell survival is through AMPK inhibition. Inositol can block AMPK activation
AntiCan⇅, The controversial effects of inositol on cancer cells may be attributed to the dual role of AMPK on cell growth.
p‑Akt↓, Inositol and inositol hexaphosphate (IP6) suppress phosphorylation of Akt via PI3K inhibition
PI3K↓,

7682- iod,    Molecular Iodine Induces Anti- and Pro-Neoplastic Effects in Prostate Cancer Models
- in-vitro, Pca, LNCaP - in-vitro, Pca, DU145 - in-vitro, Pca, PC3
PPARγ↑, Molecular iodine (I2) induces cytotoxic effects in prostate cancer cell lines and antineoplastic effects in neuroblastoma and breast cancer through the indirect activation of PPARG.
antiNeop↑,
TumCD↑, I2 promoted cytotoxic effects, whereas in surviving cells, it stimulated the outgrowth of neurite-like projections, regulated lipid content, and reduced invasive capacity.
TumCI↓,
AntiCan⇅, I2 showed anti-cancer (cytotoxic, anti-invasive) and pro-cancer (pro-neurite, lipid accumulation, desmoplasia) effects through a PPARG-independent mechanism.
antiOx↑, Prostate and prostate cancer cells capture I2, which exerts antioxidant, anti-inflammatory, and apoptotic actions depending on the cellular context
Inflam↓,
Apoptosis↑,
tumCV↓, I2 Decreases Cell Viability and Invasive Capacity in Prostate Cancer Cell Lines


Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AMPK↑, 1,   PPARγ↑, 1,  

Cell Death(tgid=5) ⓘ

p‑Akt↓, 1,   Apoptosis↑, 1,   TumCD↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

tumCV↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

PI3K↓, 1,  

Migration(tgid=13) ⓘ

TumCI↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

Inflam↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan⇅, 2,   antiNeop↑, 1,  
Total Targets: 12

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: AntiCan, Anticancer Effect
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:813  State#:%  Dir#:3
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