NA Cancer Research Results

NA, NA: Click to Expand ⟱
Source: NA
Type: NA
NA
Scientific Papers found: Click to Expand⟱
7675- HPT,    Quality assurance protocol for superficial and deep hyperthermia systems established by the Hellenic Association of Medical Physicists (HAMP) in cooperation with the Hellenic Society of Oncologic Hyperthemia (HSOH): A study based on European Society for Hyperthermic Oncology (ESHO) quality assurance guidelines
- Review, Var, NA
NA↝, The proposed protocol, applied by medical physicists in Greece, will ensure an efficient treatment with safety and minimum adverse effects.

7710- IBC,    Isobavachalcone ameliorates Alzheimer disease pathology by autophagy-mediated clearance of amyloid beta and inhibition of NLRP3 inflammasome in primary astrocytes and 5x-FAD mice
- vitro+vivo, AD, NA
*p‑AMPK↑, In-vitro analyses in astrocytes demonstrated that IBC at 5 and 10 μM concentrations induce AMPK phosphorylation through CAMKK2, promoting autophagy and inhibiting the NLRP3 inflammasome in primary astrocytes
*NLRP3↓,
*NA↝, Two months of treatment of 5x-FAD mice with IBC at 25 and 50 mg/kg significantly improved cognitive functions, as evidenced by enhanced memory and motor performance in behavioral tests.
*cognitive↑,
*memory↑,
*motorD↑,
*Aβ↓, reduce the brain’s amyloid beta levels, resulting in decreased expression of neuroinflammation markers.
*Inflam↓,
*BBB↑, IBC crossed the blood-brain barrier and improved the cognitive deficits in 5x-FAD mice

7667- IP,  H2,    Molecular hydrogen as a potential mediator of the antitumor effect of inulin consumption
*AntiTum↑, Inulin consumption and dihydrogen (H2) administration both exert antitumor effects on preclinical models as well as in clinical trials
*other↑, As H2 is one of the major byproducts of inulin fermentation by bacterial species of the gut microbiota (GM), we hypothesized that H2 could mediate the antitumor effects of inulin.
*NA↝, compared the effects on circulating immunity of a two-week daily inulin gavage with those of the corresponding H2T.
*CD4+↑, Inulin and H2T induced a similar increase in circulating CD4+ and CD8+ T cells.
*CD8+↑,
TumCG↓, both treatments similarly inhibited melanoma tumor growth
Imm↑, results support a mechanism by which the H2 resulting from inulin fermentation by the GM diffuses across the intestinal barrier and stimulates the immunosurveillance responsible for the antitumor effect.


Showing Research Papers: 1 to 3 of 3

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↝, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

TumCG↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

Imm↑, 1,  
Total Targets: 3

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

NA↝, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

p‑AMPK↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 1,   Inflam↓, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 1,   NLRP3↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiTum↑, 1,   cognitive↑, 1,   memory↑, 1,   motorD↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

CD8+↑, 1,  
Total Targets: 13

Scientific Paper Hit Count for: NA, NA
1 Hyperthermia
1 Isobavachalcone
1 Inulin Prebiotic
1 Hydrogen Gas
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:0  State#:%  Dir#:4
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