Thiols Cancer Research Results

Thiols, Thiols: Click to Expand ⟱
Source:
Type:
"Thiols" generally refer to compounds containing sulfhydryl (–SH) groups, with glutathione (GSH) being one of the most abundant and well-studied cellular thiols. Thiol groups play essential roles in maintaining redox balance, detoxifying reactive oxygen species (ROS), and modulating protein function via post-translational modifications.

• Elevated levels of glutathione and related thiols have been associated with enhanced resistance to chemotherapy and radiation, as these treatments often work by inducing oxidative damage.


Scientific Papers found: Click to Expand⟱
5154- PTL,    Parthenolide, a sesquiterpene lactone from the medical herb feverfew, shows anticancer activity against human melanoma cells in vitro
- in-vitro, Melanoma, NA
tumCV↓, MMP↓, Casp3↑, Thiols↝,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress

Thiols↝, 1,  

Mitochondria & Bioenergetics

MMP↓, 1,  

Cell Death

Casp3↑, 1,  

Transcription & Epigenetics

tumCV↓, 1,  
Total Targets: 4

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: Thiols, Thiols
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1224  State#:%  Dir#:4
wNotes=0 sortOrder:rid,rpid

 

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