Imm Cancer Research Results

Imm, immunostimulatory: Click to Expand ⟱
Source:
Type:
Enhance the immune response in patients.


Scientific Papers found: Click to Expand⟱
5948- Cela,    Recent Trends in anti-tumor mechanisms and molecular targets of celastrol
TumCP↓, TumCCA↑, Apoptosis↑, TumAuto↑, TumCI↓, TumMeta↓, Imm↝, angioG↓, Cyt‑c↑, ROS↑, BAX↑, Casp3↑, Casp9↑, cl‑PARP↑, PrxII↓, ER Stress↑, mtDam↑, CHOP/DDIT3↑, Inflam↓, NF-kB↓, CXCR4↓, MMP9↓, IL6↓, TNF-α↓, HSP90↓, neuroP↑, STAT3↓, Prx↓, HO-1↑, eff↑, eff↑, BioAv↑, toxicity↑, CardioT↑, hepatoP↓,
7013- Fuc,    Fucoidan-based nanoparticles for colorectal cancer therapy: Mechanisms and preclinical insights
- Review, CRC, NA
*Inflam↓, *antiOx↑, AntiCan↑, BioAv↑, Apoptosis↑, angioG↓, Imm↝, ChemoSen↑, chemoP↑,
7008- Fuc,    Ten Years of Research on Fucoidan and Cancer: Focus on Its Antiangiogenic and Antimetastatic Effects
- Review, Var, NA
antiOx↑, AntiViral↑, Imm↝, *AntiThr↑, *AntiDiabetic↑, AntiTum↑, TumMeta↑, angioG↓, Hif1a↓, VEGF↓, MMPs↓, EMT↓, N-cadherin↓, E-cadherin↑, TIMP1↑, PI3K↓, Akt↓, mTOR↓, MMP2↓, ChemoSen↑, OS↑, fatigue↓, CD31/PECAM-1↓,
7341- Hne,    Preclinical evaluation of safety and potential of black hellebore extracts for cancer treatment
- Review, Var, NA
angioG↓, TumCP↓, *Inflam↓, *Bacteria↓, *glucose↓, *neuroP↓, *hepatoP↓, *Imm↝,
7455- HNK,    Honokiol in cancer: Roles in enhancing combination therapy efficacy and preventing post-transplant malignancies
- Review, Var, NA
ChemoSen↑, Imm↝, *hepatoP↑, *cardioP↑, *neuroP↑, *AntiCan↑, *Inflam↓, *antiOx↑, eff↑, *TNF-α↓, *IL1?, *IL6?,
7900- IVT,    Isovitexin: A Promising Active Compound Found in Nature's Bounty
- in-vivo, Nor, NA
*BioAv↓, *Imm↝, *antiOx↑, *AntiCan↑, *neuroP↑, *hepatoP↑, *Inflam↓, *NF-kB↓, *MAPK↓, *MPO↓, *ROS↓, TumAuto↑, Apoptosis↑,
4092- MF,    Mechanisms and therapeutic effectiveness of pulsed electromagnetic field therapy in oncology
- Review, Var, NA
Apoptosis↑, selectivity↑, ROS↑, Catalase↓, TumVol↓, angioG↓, Ca+2↝, eff↝, angioG↓, Imm↝, TNF-α↑, Casp8↑,

Showing Research Papers: 1 to 7 of 7

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 7

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1)

antiOx↑, 1,   Catalase↓, 1,   HO-1↑, 1,   Prx↓, 1,   PrxII↓, 1,   ROS↑, 2,  

Mitochondria & Bioenergetics(tgid=3)

mtDam↑, 1,  

Cell Death(tgid=5)

Akt↓, 1,   Apoptosis↑, 4,   BAX↑, 1,   Casp3↑, 1,   Casp8↑, 1,   Casp9↑, 1,   Cyt‑c↑, 1,  

Protein Folding & ER Stress(tgid=8)

CHOP/DDIT3↑, 1,   ER Stress↑, 1,   HSP90↓, 1,  

Autophagy & Lysosomes(tgid=9)

TumAuto↑, 2,  

DNA Damage & Repair(tgid=10)

cl‑PARP↑, 1,  

Cell Cycle & Senescence(tgid=11)

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12)

EMT↓, 1,   mTOR↓, 1,   PI3K↓, 1,   STAT3↓, 1,  

Migration(tgid=13)

Ca+2↝, 1,   CD31/PECAM-1↓, 1,   E-cadherin↑, 1,   MMP2↓, 1,   MMP9↓, 1,   MMPs↓, 1,   N-cadherin↓, 1,   TIMP1↑, 1,   TumCI↓, 1,   TumCP↓, 2,   TumMeta↓, 1,   TumMeta↑, 1,  

Angiogenesis & Vasculature(tgid=14)

angioG↓, 6,   Hif1a↓, 1,   VEGF↓, 1,  

Immune & Inflammatory Signaling(tgid=16)

CXCR4↓, 1,   IL6↓, 1,   Imm↝, 5,   Inflam↓, 1,   NF-kB↓, 1,   TNF-α↓, 1,   TNF-α↑, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↑, 2,   ChemoSen↑, 3,   eff↑, 3,   eff↝, 1,   selectivity↑, 1,  

Clinical Biomarkers(tgid=22)

IL6↓, 1,  

Functional Outcomes(tgid=23)

AntiCan↑, 1,   AntiTum↑, 1,   CardioT↑, 1,   chemoP↑, 1,   fatigue↓, 1,   hepatoP↓, 1,   neuroP↑, 1,   OS↑, 1,   toxicity↑, 1,   TumVol↓, 1,  

Infection & Microbiome(tgid=24)

AntiViral↑, 1,  
Total Targets: 63

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1)

antiOx↑, 3,   MPO↓, 1,   ROS↓, 1,  

Core Metabolism/Glycolysis(tgid=4)

glucose↓, 1,  

Cell Death(tgid=5)

MAPK↓, 1,  

Transcription & Epigenetics(tgid=7)

AntiThr↑, 1,  

Immune & Inflammatory Signaling(tgid=16)

IL1?, 1,   IL6?, 1,   Imm↝, 2,   Inflam↓, 4,   NF-kB↓, 1,   TNF-α↓, 1,  

Drug Metabolism & Resistance(tgid=21)

BioAv↓, 1,  

Clinical Biomarkers(tgid=22)

IL6?, 1,  

Functional Outcomes(tgid=23)

AntiCan↑, 2,   AntiDiabetic↑, 1,   cardioP↑, 1,   hepatoP↓, 1,   hepatoP↑, 2,   neuroP↓, 1,   neuroP↑, 2,  

Infection & Microbiome(tgid=24)

Bacteria↓, 1,  
Total Targets: 22

Scientific Paper Hit Count for: Imm, immunostimulatory
2 Fucoidan
1 Celastrol
1 Helleborus niger extracts – Christmas Rose
1 Honokiol
1 Isovitexin
1 Magnetic Fields
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1332  State#:%  Dir#:4
wNotes=0 sortOrder:rid,rpid

 

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