miR-21 Cancer Research Results

miR-21, miR-21: Click to Expand ⟱
Source:
Type:
miR-21 is often considered an oncogenic microRNA because its overexpression is frequently observed in many cancers. It can promote tumor growth and progression by targeting and downregulating tumor suppressor genes.


Scientific Papers found: Click to Expand⟱
810- GAR,  GEM,    Garcinol sensitizes human pancreatic adenocarcinoma cells to gemcitabine in association with microRNA signatures
- in-vitro, PC, NA
TumCP↓, Apoptosis↑, PARP↝, VEGF↝, MMPs↝, Casp↝, NF-kB↝, miR-21↝,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death

Apoptosis↑, 1,   Casp↝, 1,  

Transcription & Epigenetics

miR-21↝, 1,  

DNA Damage & Repair

PARP↝, 1,  

Migration

MMPs↝, 1,   TumCP↓, 1,  

Angiogenesis & Vasculature

VEGF↝, 1,  

Immune & Inflammatory Signaling

NF-kB↝, 1,  
Total Targets: 8

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: miR-21, miR-21
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:191  State#:%  Dir#:4
wNotes=0 sortOrder:rid,rpid

 

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