GSTP1/GSTπ Cancer Research Results

GSTP1/GSTπ, Glutathione S-transferase pi 1: Click to Expand ⟱

Source:

Type:

An enzyme that plays a crucial role in the detoxification of various substances, including carcinogens. It is also involved in the regulation of cellular processes, such as cell growth, differentiation, and apoptosis.
GSTP1 is overexpressed in various types of cancer, including prostate, breast, lung, and colon cancer. The overexpression of GSTP1 has been associated with cancer progression, metastasis, and poor prognosis.

Scientific Papers found: Click to Expand⟱

992-

PL,

Piperlongumine based nanomedicine impairs glycolytic metabolism in triple negative breast cancer stem cells through modulation of GAPDH & FBP1

in-vivo,

BC,

zebrafish and nude mice

EPR↓, Glycolysis↓, GAPDH↓, GSTP1/GSTπ↝, FBPase↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Redox & Oxidative Stress ⓘ

GSTP1/GSTπ↝, 1,

Core Metabolism/Glycolysis ⓘ

FBPase↑, 1, GAPDH↓, 1, Glycolysis↓, 1,

Angiogenesis & Vasculature ⓘ

EPR↓, 1,
Total Targets: 5

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: GSTP1/GSTπ, Glutathione S-transferase pi 1

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells