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4051-   Long-term association of food and nutrient intakes with cognitive and functional decline: a 13-year follow-up study of elderly French women
- Study, AD, NA
*cognitive↑, *neuroP↑, *other↝, *other⇅,
2327- 2DG,    2-Deoxy-d-Glucose and Its Analogs: From Diagnostic to Therapeutic Agents
- Review, Var, NA
Glycolysis↓, HK2↓, mt-ROS↑, AMPK↑, PPP↓, NADPH↓, GSH↓, Bax:Bcl2↑, Apoptosis↑, RadioS↑, eff↓, Half-Life↓, other↝, eff↓,
5270- 5-ALA,  PDT,    5-Aminolevulinic Acid as a Theranostic Agent for Tumor Fluorescence Imaging and Photodynamic Therapy
- Review, Var, NA
other↝, ROS↑, other↝, mtDam↑, Ca+2↑, ER Stress↑, Apoptosis↑, TumAuto↑, other↝, Dose↝, Imm↑,
5297- 5-HTP,    Targeting 5-HT Is a Potential Therapeutic Strategy for Neurodegenerative Diseases
- in-vivo, AD, NA - in-vivo, Park, NA
*other↝, *cognitive↑, *memory↑, *Ach↑,
5293- 5-HTP,    The Role of Tryptophan Metabolism in Alzheimer’s Disease
- in-vivo, AD, NA
*Sleep↑, *5HT↑, *memory↑, *other↝,
5292- 5-HTP,    Past, present, and future of serotonin-targeting therapeutics for Alzheimer’s disease: Perspectives from DNA methylation
- Review, AD, NA
*other↝, *cognitive↝,
5457- AF,    Clinical pharmacokinetics of oral and injectable gold compounds
- Human, Nor, NA
*BioAv↝, *Dose↝, *Half-Life↑, *BioAv↝, *other↝,
5470- AF,    Exploring a Therapeutic Gold Mine: The Antifungal Potential of the Gold-Based Antirheumatic Drug Auranofin
- Review, Var, NA
TrxR↓, other↝, IL6↑, IL8↑, NK cell⇅, COX2↓, NOS2↓, NRF2↑, Prx↑, Half-Life↑, Dose↝, ROS↑, NF-kB↓,
5429- AG,    Astragalus polysaccharides improve adjuvant chemotherapy-induced fatigue for patients with early breast cancer
- Human, BC, NA
chemoP↑, other↝,
4400- AgNPs,  Rad,    Differential cytotoxic and radiosensitizing effects of silver nanoparticles on triple-negative breast cancer and non-triple-negative breast cells
- in-vitro, BC, MCF-7 - in-vitro, Nor, MCF10 - in-vitro, BC, MDA-MB-231 - in-vitro, BC, BT549 - in-vivo, BC, MDA-MB-231
ROS↑, DNAdam↑, selectivity↑, TumCG↓, RadioS↑, Dose↝, selectivity↑, other↝, eff↓, eff↑, γH2AX↑, Dose↓, eff↑,
4421- AgNPs,    Effect of Biologically Synthesized Silver Nanoparticles on Human Cancer Cells
- in-vitro, Cerv, NA
selectivity↑, eff↝, other↝,
4419- AgNPs,    Tackling the various classes of nano-therapeutics employed in topical therapy of psoriasis
- NA, PSA, NA
IL1α↓, other↝,
4360- AgNPs,    Silver Nanoparticles as Real Topical Bullets for Wound Healing
- Study, Nor, NA
*other↝, *toxicity↓, *eff↑, *eff↑, *Inflam↓, *IL6↓, *TGF-β↑, *MMP9↓, *eff↑,
4359- AgNPs,    Antimicrobial Silver Nanoparticles for Wound Healing Application: Progress and Future Trends
- NA, Wounds, NA
*Bacteria↓, *eff↑, *other↝, *toxicity↓,
4367- AgNPs,    Effects of Prolonged Silver Nanoparticle Exposure on the Contextual Cognition and Behavior of Mammals
- in-vivo, Nor, NA
*other↝,
4562- AgNPs,  VitC,    Eco-friendly Synthesis of Silver Nanoparticles using Ascorbic Acid and its Optical Characterization
- Study, NA, NA
*other↑, *other↝,
4561- AgNPs,  VitC,    Cellular Effects Nanosilver on Cancer and Non-cancer Cells: Potential Environmental and Human Health Impacts
- in-vitro, CRC, HCT116 - in-vitro, Nor, HEK293
NRF2↑, TumCCA↑, ROS↑, selectivity↑, *AntiViral↑, *toxicity↝, ETC↓, MMP↓, DNAdam↑, Apoptosis↑, lipid-P↑, other↝, UPR↑, *GRP78/BiP↑, *p‑PERK↑, *cl‑eIF2α↑, *CHOP↑, *JNK↑, Hif1a↓, AntiCan↑, *toxicity↓, eff↑,
4549- AgNPs,    Silver nanoparticles: Synthesis, medical applications and biosafety
- Review, Var, NA - Review, Diabetic, NA
ROS↑, eff↑, other↝, DNAdam↑, EPR↑, eff↑, eff↑, TumMeta↓, angioG↓, *Bacteria↓, *eff↑, *AntiViral↑, *AntiFungal↑, eff↑, eff↑, TumCP↓, tumCV↓, P53↝, HIF-1↓, TumCCA↑, lipid-P↑, ATP↓, Cyt‑c↑, MMPs↓, PI3K↓, Akt↓, *Wound Healing↑, *Inflam↓, *Bone Healing↑, *glucose↓, *AntiDiabetic↑, *BBB↑,
4545- AgNPs,  VitC,  Citrate,    Ascorbic Acid-assisted Green Synthesis of Silver Nanoparticles: pH and Stability Study
- Study, NA, NA
*other↝, *other↝, *eff↑, *eff↑,
4600- AgNPs,    Effects of particle size and coating on toxicologic parameters, fecal elimination kinetics and tissue distribution of acutely ingested silver nanoparticles in a mouse model
- in-vivo, Nor, NA
*Half-Life↝, *toxicity↓, *Dose↑, *other↝, *eff↝, *BioAv↓,
4586- AgNPs,    Tyndall-effect-enhanced supersensitive naked-eye determination of mercury (II) ions with silver nanoparticles
*other↝, *other↝,
4585- AgNPs,    Tyndall-effect-based colorimetric assay with colloidal silver nanoparticles for quantitative point-of-care detection of creatinine using a laser pointer pen and a smartphone
*other↝,
305- AgNPs,    Activity and pharmacology of homemade silver nanoparticles in refractory metastatic head and neck squamous cell cancer
- Case Report, HNSCC, NA
OS↑, Dose↓, BioAv↝, toxicity↓, Remission↑, other↝, other↝, other↝, Dose↝, BioAv↝,
391- AgNPs,    Silver nanoparticles inhibit VEGF-and IL-1β-induced vascular permeability via Src dependent pathway in porcine retinal endothelial cells
- in-vitro, Nor, NA
*VEGF↓, *IL1↓, toxicity↝, other↝,
5343- Ajoene,    The garlic compound ajoene covalently binds vimentin, disrupts the vimentin network and exerts anti-metastatic activity in cancer cells
- in-vitro, Cerv, HeLa - in-vitro, BC, MDA-MB-231
Vim↑, TumCI↓, TumCMig↓, TumMeta↓, Vim↓, other↝,
2667- AL,    Allicin in Digestive System Cancer: From Biological Effects to Clinical Treatment
- Review, GC, NA
AntiCan↑, ChemoSen↑, angioG↓, chemoP↑, *GutMicro↑, *antiOx↑, other↝, GSH↓, Thiols↓, *ROS↓, *hepatoP↑, *Inflam↓, *NF-kB↓,
550- AL,    A Review on Anticancer Activities of Garlic (Allium sativum L.)
- Review, NA, NA
ChemoSideEff↓, other↝,
3270- ALA,    Alpha-lipoic acid as a new treatment option for Alzheimer's disease--a 48 months follow-up analysis
- Trial, AD, NA
*cognitive↑, *other↝, *neuroP↑, *IronCh↑, *ROS↓, *GSH↑,
3443- ALA,    Molecular and Therapeutic Insights of Alpha-Lipoic Acid as a Potential Molecule for Disease Prevention
- Review, Var, NA - Review, AD, NA
*antiOx↑, *ROS↓, *IronCh↑, *cognitive↑, *cardioP↓, AntiCan↑, *neuroP↑, *Inflam↓, *BioAv↓, *AntiAge↑, *Half-Life↓, *BioAv↝, other↝, EGFR↓, Akt↓, ROS↓, TumCCA↑, p27↑, PDH↑, Glycolysis↓, ROS↑, *eff↑, *memory↑, *motorD↑, *GutMicro↑,
3549- ALA,    Important roles of linoleic acid and α-linolenic acid in regulating cognitive impairment and neuropsychiatric issues in metabolic-related dementia
- Review, AD, NA
*Inflam↓, *other↝, *other↝, *neuroP↑, *BioAv↝, *adiP↑, *BBB↑, *Casp6↓, *Casp9↓, *TNF-α↓, *IL6↓, *IL1β↓, *ROS↓, *NO↓, *iNOS↓, *COX2↓, *JNK↓, *p‑NF-kB↓, *Aβ↓, *BP↓, *memory↑, *cAMP↑, *ERK↑, *Akt↑, cognitive?,
297- ALA,    Insights on the Use of α-Lipoic Acid for Therapeutic Purposes
- Review, BC, SkBr3 - Review, neuroblastoma, SK-N-SH - Review, AD, NA
PDH↑, TumCG↓, ROS↑, AMPK↑, EGR4↓, Half-Life↓, BioAv↝, *GSH↑, *IronCh↑, *ROS↓, *antiOx↑, *neuroP↑, *Ach↑, *lipid-P↓, *IL1β↓, *IL6↓, TumCP↓, FDG↓, Apoptosis↑, AMPK↑, mTOR↓, EGFR↓, TumCI↓, TumCMig↓, *memory↑, *BioAv↑, *BioAv↝, *other↓, *other↝, *Half-Life↓, *BioAv↑, *ChAT↑, *GlucoseCon↑,
4512- aLinA,  GLA,    Evening primrose oil: a comprehensive review of its bioactives, extraction, analysis, oil quality, therapeutic merits, and safety
- in-vivo, Nor, NA
*other↝,
4135- Alum,    Aluminum Should Now Be Considered a Primary Etiological Factor in Alzheimer's Disease
- Review, AD, NA
*Risk↑, *cognitive↓, *neuroP↓, *other↑, *other↝,
4758- antiOx,  Chemo,    Therapeutic controversies over use of antioxidant supplements during cancer treatment: a scoping review
- Review, Var, NA
ChemoSen↓, other↝, other↝,
4746- antiOx,  Chemo,  VitA,RetA,  VitC,  Se  Using Supplements During Chemo: Yes or No?
- Review, Var, NA
eff↓, ChemoSen↓, RadioS↓, other↝,
2637- Api,    Apigenin Alleviates Endoplasmic Reticulum Stress-Mediated Apoptosis in INS-1 β-Cells
- in-vitro, Diabetic, NA
*other↝, *Insulin↑, ER Stress↓, *CHOP↓, *cl‑Casp3↓, *ROS↓, *Inflam↓, *TXNIP↓,
2320- ART/DHA,    Dihydroartemisinin Inhibits the Proliferation of Leukemia Cells K562 by Suppressing PKM2 and GLUT1 Mediated Aerobic Glycolysis
- in-vitro, AML, K562 - in-vitro, Liver, HepG2
Glycolysis↓, GlucoseCon↓, lactateProd↓, GLUT1↓, PKM2↓, ECAR↓, LDHA↓, cMyc↓, other↝,
2580- ART/DHA,  VitC,    Effects of Antioxidants and Pro-oxidants on Cytotoxicity of Dihydroartemisinin to Molt-4 Human Leukemia Cells
- in-vitro, AML, NA
eff↓, other↝, ROS↑, eff↓, eff↓,
5403- ASA,    Low-Dose Aspirin for PI3K-Altered Localized Colorectal Cancer
- Trial, CRC, NA
Risk↓, other↝,
5413- ASA,    Drug Resistance and Pseudoresistance: An Unintended Consequence of Enteric Coating Aspirin
- Trial, Nor, NA
*cardioP↑, *other↝, *COX1↓, *TXA2↓,
5399- ASA,    Effect of Aspirin on Cancer Incidence and Mortality in Older Adults
- Trial, Nor, NA
Risk↝, Risk↑, Risk∅, Risk↑, other↝,
5404- ASA,    Low-Dose Aspirin and Prevention of Colorectal Cancer: Evidence From a Nationwide Registry-Based Cohort in Norway
- Study, CRC, NA
Risk↓, other↝, Dose↝, Risk↓, other↓, other↝, KRAS↓, other↓, other↓,
5393- Ash,    Studies on oral bioavailability and first-pass metabolism of withaferin A in rats using LC-MS/MS and Q-TRAP
- in-vivo, Nor, NA
*BioAv↝, *other↝, *Half-Life↓,
5453- ATV,    Epidemiologic Analysis Along the Mevalonate Pathway Reveals Improved Cancer Survival in Patients Who Receive Statins Alone and in Combination With Bisphosphonates
- Trial, Var, NA
OS↑, eff↑, other↝,
5504- Ba,    Comparative Pharmacokinetics of Baicalin, Wogonoside, Baicalein and Wogonin in Plasma after Oral Administration of Pure Baicalin, Radix Scutellariae and Scutellariae-Paeoniae Couple Extracts in Normal and Ulcerative Colitis Rats
- in-vivo, Nor, NA
*BioAv↝, *other↝,
2712- BBR,    Suppression of colon cancer growth by berberine mediated by the intestinal microbiota and the suppression of DNA methyltransferases (DNMTs)
- in-vitro, Colon, HT29 - in-vivo, NA, NA
TumCG↓, GutMicro↑, other↝, IL10↓, cMyc↓, DNMT1↓, DNMTs↓,
5640- BCA,    Improved effectiveness of biochanin A as a P-gp inhibitor in solid dispersion
- in-vitro, Nor, NA
*P-gp↓, BioAv↑, other↝, other↑,
5512- bemA,    Recent advance of ATP citrate lyase inhibitors for the treatment of cancer and related diseases
- Review, Var, NA
ACLY↓, other↝, CSCs↓,
5513- bemA,    ACLY inhibition promotes tumour immunity and suppresses liver cancer
- in-vitro, Liver, NA
ACLY↓, AMPK↑, eff↑, other↝, eff↝,
4061- betaCar,  VitB12,  VitB6,  FA,  VitB3  Revisiting the Role of Vitamins and Minerals in Alzheimer’s Disease
- Review, AD, NA
*cognitive↑, *cognitive↑, *Inflam↓, *homoC↓, *TNF-α↓, *other↝, *memory↑,

Showing Research Papers: 1 to 50 of 189
Page 1 of 4 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 189

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress

GSH↓, 2,   lipid-P↑, 2,   NRF2↑, 2,   Prx↑, 1,   ROS↓, 1,   ROS↑, 8,   mt-ROS↑, 1,   Thiols↓, 1,   TrxR↓, 1,  

Mitochondria & Bioenergetics

ATP↓, 1,   ETC↓, 1,   MMP↓, 1,   mtDam↑, 1,  

Core Metabolism/Glycolysis

ACLY↓, 2,   AMPK↑, 4,   cMyc↓, 2,   ECAR↓, 1,   FDG↓, 1,   GlucoseCon↓, 1,   Glycolysis↓, 3,   HK2↓, 1,   lactateProd↓, 1,   LDHA↓, 1,   NADPH↓, 1,   PDH↑, 2,   PKM2↓, 1,   PPP↓, 1,  

Cell Death

Akt↓, 2,   Apoptosis↑, 4,   Bax:Bcl2↑, 1,   Cyt‑c↑, 1,   p27↑, 1,  

Transcription & Epigenetics

other↓, 3,   other↑, 1,   other↝, 33,   tumCV↓, 1,  

Protein Folding & ER Stress

ER Stress↓, 1,   ER Stress↑, 1,   UPR↑, 1,  

Autophagy & Lysosomes

TumAuto↑, 1,  

DNA Damage & Repair

DNAdam↑, 3,   DNMT1↓, 1,   DNMTs↓, 1,   P53↝, 1,   γH2AX↑, 1,  

Cell Cycle & Senescence

TumCCA↑, 3,  

Proliferation, Differentiation & Cell State

CSCs↓, 1,   mTOR↓, 1,   PI3K↓, 1,   TumCG↓, 3,  

Migration

Ca+2↑, 1,   KRAS↓, 1,   MMPs↓, 1,   TumCI↓, 2,   TumCMig↓, 2,   TumCP↓, 2,   TumMeta↓, 2,   Vim↓, 1,   Vim↑, 1,  

Angiogenesis & Vasculature

angioG↓, 2,   EGFR↓, 2,   EGR4↓, 1,   EPR↑, 1,   HIF-1↓, 1,   Hif1a↓, 1,  

Barriers & Transport

GLUT1↓, 1,  

Immune & Inflammatory Signaling

COX2↓, 1,   IL10↓, 1,   IL1α↓, 1,   IL6↑, 1,   IL8↑, 1,   Imm↑, 1,   NF-kB↓, 1,   NK cell⇅, 1,  

Drug Metabolism & Resistance

BioAv↑, 1,   BioAv↝, 3,   ChemoSen↓, 2,   ChemoSen↑, 1,   Dose↓, 2,   Dose↝, 5,   eff↓, 7,   eff↑, 10,   eff↝, 2,   Half-Life↓, 2,   Half-Life↑, 1,   RadioS↓, 1,   RadioS↑, 2,   selectivity↑, 4,  

Clinical Biomarkers

EGFR↓, 2,   GutMicro↑, 1,   IL6↑, 1,   KRAS↓, 1,   NOS2↓, 1,  

Functional Outcomes

AntiCan↑, 3,   chemoP↑, 2,   ChemoSideEff↓, 1,   cognitive?, 1,   OS↑, 2,   Remission↑, 1,   Risk↓, 3,   Risk↑, 2,   Risk↝, 1,   Risk∅, 1,   toxicity↓, 1,   toxicity↝, 1,  
Total Targets: 105

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

antiOx↑, 3,   GSH↑, 2,   lipid-P↓, 1,   ROS↓, 6,  

Metal & Cofactor Biology

IronCh↑, 3,  

Mitochondria & Bioenergetics

Insulin↑, 1,  

Core Metabolism/Glycolysis

adiP↑, 1,   cAMP↑, 1,   glucose↓, 1,   GlucoseCon↑, 1,   homoC↓, 1,  

Cell Death

Akt↑, 1,   cl‑Casp3↓, 1,   Casp6↓, 1,   Casp9↓, 1,   iNOS↓, 1,   JNK↓, 1,   JNK↑, 1,  

Transcription & Epigenetics

Ach↑, 2,   other↓, 1,   other↑, 2,   other⇅, 1,   other↝, 26,  

Protein Folding & ER Stress

CHOP↓, 1,   CHOP↑, 1,   cl‑eIF2α↑, 1,   GRP78/BiP↑, 1,   p‑PERK↑, 1,  

Proliferation, Differentiation & Cell State

ERK↑, 1,  

Migration

MMP9↓, 1,   TGF-β↑, 1,   TXNIP↓, 1,  

Angiogenesis & Vasculature

NO↓, 1,   TXA2↓, 1,   VEGF↓, 1,  

Barriers & Transport

BBB↑, 2,   P-gp↓, 1,  

Immune & Inflammatory Signaling

COX1↓, 1,   COX2↓, 1,   IL1↓, 1,   IL1β↓, 2,   IL6↓, 3,   Inflam↓, 7,   NF-kB↓, 1,   p‑NF-kB↓, 1,   TNF-α↓, 2,  

Synaptic & Neurotransmission

5HT↑, 1,   ChAT↑, 1,  

Protein Aggregation

Aβ↓, 1,  

Drug Metabolism & Resistance

BioAv↓, 2,   BioAv↑, 2,   BioAv↝, 7,   Dose↑, 1,   Dose↝, 1,   eff↑, 8,   eff↝, 1,   Half-Life↓, 3,   Half-Life↑, 1,   Half-Life↝, 1,  

Clinical Biomarkers

BP↓, 1,   GutMicro↑, 2,   IL6↓, 3,  

Functional Outcomes

AntiAge↑, 1,   AntiDiabetic↑, 1,   Bone Healing↑, 1,   cardioP↓, 1,   cardioP↑, 1,   cognitive↓, 1,   cognitive↑, 6,   cognitive↝, 1,   hepatoP↑, 1,   memory↑, 6,   motorD↑, 1,   neuroP↓, 1,   neuroP↑, 5,   Risk↑, 1,   Sleep↑, 1,   toxicity↓, 4,   toxicity↝, 1,   Wound Healing↑, 1,  

Infection & Microbiome

AntiFungal↑, 1,   AntiViral↑, 2,   Bacteria↓, 2,  
Total Targets: 83

Scientific Paper Hit Count for: other, other
16 Silver-NanoParticles
11 Vitamin C (Ascorbic Acid)
9 Folic Acid, Vit B9
9 Magnetic Fields
8 Selenium NanoParticles
8 Selenite (Sodium)
7 Selenium
7 chitosan
6 Vitamin B12
6 Hydrogen Gas
5 Chemotherapy
5 Choline
5 Vitamin B5,Pantothenic Acid
4 Alpha-Lipoic-Acid
4 Aspirin -acetylsalicylic acid
4 Curcumin
3 5-Hydroxytryptophan
3 Radiotherapy/Radiation
3 Anti-oxidants
3 Vitamin B6,pyridoxine
3 borneol
3 Boron
3 Coenzyme Q10
3 EGCG (Epigallocatechin Gallate)
3 Electrical Pulses
3 Vitamin E
3 Potassium
3 Vitamin B1/Thiamine
3 Vitamin D3
2 Auranofin
2 Allicin (mainly Garlic)
2 Artemisinin
2 bempedoic acid
2 Bufalin/Huachansu
2 brusatol
2 Butyrate
2 Carnosic acid
2 Celastrol
2 diet Methionine-Restricted Diet
2 Magnetic Field Rotating
2 Peppermint
2 Phenylbutyrate
2 Phenethyl isothiocyanate
2 probiotics
2 Taurine
1 2-DeoxyGlucose
1 5-Aminolevulinic acid
1 Photodynamic Therapy
1 Astragalus
1 Citric Acid
1 Ajoene (compound of Garlic)
1 alpha Linolenic acid
1 γ-linolenic acid (Borage Oil)
1 Aluminum
1 Vitamin A, Retinoic Acid
1 Apigenin (mainly Parsley)
1 Ashwagandha(Withaferin A)
1 Atorvastatin
1 Baicalein
1 Berberine
1 Biochanin A
1 beta-carotene(VitA)
1 Vitamin B3,Niacin
1 Brucea javanica
1 Bacopa monnieri
1 Bortezomib
1 Bruteridin(bergamot juice)
1 Capsaicin
1 Caffeic Acid Phenethyl Ester (CAPE)
1 Carvacrol
1 Cannabidiol
1 Chlorogenic acid
1 Chlorophyllin
1 Camptothecin
1 irinotecan
1 Cysteamine
1 Fisetin
1 Shilajit/Fulvic Acid
1 Germanium
1 Genistein (soy isoflavone)
1 Resveratrol
1 Sulforaphane (mainly Broccoli)
1 Ginseng
1 Laetrile B17 Amygdalin
1 Methylglyoxal
1 Piperlongumine
1 Parthenolide
1 Ramucirumab (CYRAMZA)
1 Radio Frequency
1 Rosmarinic acid
1 Aromatherapy
1 salinomycin
1 SonoDynamic Therapy UltraSound
1 Oxygen, Hyperbaric
1 Shankhpushpi
1 Shikonin
1 Thymoquinone
1 Urolithin
1 diet Short Term Fasting
1 glucose deprivation
1 Exercise
1 Vitamin K2
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:767  State#:%  Dir#:4
wNotes=0 sortOrder:rid,rpid

 

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