AntiAg Cancer Research Results

AntiAg, Antiplatelet aggregation: Click to Expand ⟱
Source:
Type:
Antiplatelet aggregation refers to the process by which platelets clump together to form a blood clot.
The plethora of evidence indicates that among multiple hemostasis components, platelets play major roles in cancer progression by providing surface and granular contents for several interactions as well as behaving like immune cells.On the other hand, there are suggestions that antiplatelet treatment may promote solid tumor development in a phenomenon described as “cancers follow bleeding.” The controversies around antiplatelet agents justify insight into the subject to establish what, if any, role platelet-directed therapy has in the continuum of anticancer management.
The interplay between antiplatelet aggregation and cancer is an area of active research, with potential implications for therapeutic strategies. Antiplatelet agents, such as aspirin, are being investigated for their role in cancer prevention and treatment, particularly in reducing metastasis and improving patient outcomes.
Scientific Papers found: Click to Expand⟱
2462- AL,    Comparison of antiplatelet activity of garlic tablets with cardio-protective dose of aspirin in healthy volunteers: a randomized clinical trial
- Trial, Nor, NA
AntiAg∅, Garlic tablet did not have significant effect on PA at any dose.

7241- EGb 761,  ASA,    Effect of Ginkgo biloba (EGb 761) and aspirin on platelet aggregation and platelet function analysis among older adults at risk of cardiovascular disease: a randomized clinical trial
- Trial, Nor, NA
*Dose↝, (EGb 761, 300 mg/day) was compared with placebo for effects on measures of platelet aggregation among adults consuming 325 mg/day aspirin in a randomized, double-blind, placebo-controlled
*AntiAg∅, In conclusion, in older adults with PAD or cardiovascular disease risk, a relatively high dose of Ginkgo biloba combined with 325 mg/day daily aspirin did not have a clinically or statistically detectable impact on indices of coagulation examined ove

7190- GBE,    Is there a risk of bleeding associated with standardized Ginkgo biloba extract therapy? A systematic review and meta-analysis
- Review, Nor, NA
*AntiAg∅, no evidence of any effect on measures of platelet function (ADP-induced platelet aggregation) and coagulation (fibrinogen concentration, aPTT, PT).
*other∅, Existing evidence has also not established an increased risk of bleeding with GBE in combination with anticoagulants or platelet aggregation inhibitors.

2464- GI,    The Effect of Ginger (Zingiber officinale) on Platelet Aggregation: A Systematic Literature Review
- Review, Nor, NA
*Inflam↓, gingerol and shogaol classes of compounds, might exert several beneficial effects including anti-inflammatory, antioxidant, and cholesterol lowering properties
*antiOx↑,
*LDL↓,
*AntiAg↑, previous clinical trials report few side-effects, mostly minor in nature (e.g. mild nausea, heartburn).[1] Of these reported side effects, potentially the most significant is an antiplatelet effect.
*AntiAg∅, In contrast, two studies reported that 2–3.6g of ginger had no effect on measures of platelet aggregation in health adults.


Showing Research Papers: 1 to 4 of 4

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 4

Pathway results for Effect on Cancer / Diseased Cells:


Migration(tgid=13) ⓘ

AntiAg∅, 1,  
Total Targets: 1

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

LDL↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other∅, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 1,   AntiAg∅, 3,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

Inflam↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 1,  
Total Targets: 7

Scientific Paper Hit Count for: AntiAg, Antiplatelet aggregation
1 Allicin (mainly Garlic)
1 Ginkgo biloba-EGb 761
1 Aspirin
1 Ginkgo biloba
1 Ginger/6-Shogaol/Gingerol
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:10  State#:%  Dir#:6
  wNotes=on  sortOrder:rid,rpid

 

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