eff Cancer Research Results
eff, efficacy: Click to Expand ⟱
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Power to enhance an anti cancer effect
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Scientific Papers found: Click to Expand⟱
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in-vitro, |
Pca, |
PC3 |
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in-vitro, |
Pca, |
LNCaP |
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in-vitro, |
Pca, |
DU145 |
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in-vivo, |
NA, |
NA |
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TumCP↓, P53↑, P21↑, BAX↑, PSA↓, AR↓, NF-kB↓, Proteasome↓, TumVol↓, eff∅,
Dose↝, *DNArepair↑, toxicity↝, BioAv↝, eff∅,
eff∅, Dose↝, CardioT↑,
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Review, |
Nor, |
NA |
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Review, |
AD, |
NA |
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*BioAv↝, *Dose↝, *cardioP↑, *BP↓, *cognitive↑, *memory↑, eff∅,
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in-vitro, |
BC, |
SUM159 |
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in-vitro, |
BC, |
4T1 |
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PI3K↑, Akt↑, mTOR↑, CDK4↑, CDK6↑, hyperG↓, TumCG↓, TumVol↓, Casp3↑, BG↓, eff↑, eff∅, PKA↓, KLF5↓, p‑GSK‐3β↑, Nanog↓, OCT4↓, KLF2↓, eff↑, ROS↑, BIM↑, ASK1↑, PI3K↑, Akt↑, mTOR↑, CDK1↓, CDK4↑, CDK6↑, eff↑,
eff↑, TumCD↑, MusCon↓, Temp↓, eff↑, eff↓, eff↑, eff∅, other↑,
TumCCA↑, cl‑PARP↑, Apoptosis↑, Casp↑, P53↑, DR5↑, CHOP↑, ROS↑, ER Stress↑, ATF4↑, XBP-1↑, eff∅,
MMPs↓, angioG↓, TumMeta↓, TumCCA↑, Apoptosis↑, ChemoSideEff↓, eff∅, HDAC↓, PTEN↑, p‑PTEN↓, p‑Akt↓, Casp3↑, p‑ERK↑, p‑FAK↑, Dose?, Akt↓, GSK‐3β↓, FOXO3↓, eff↑, IL2↑, IL10↑, NF-kB↓, VEGF↓, mtDam↑, ER Stress↑, AST↓, ALAT↓, ALP↓, COX2↓, eff↑, Bax:Bcl2↑,
Risk↓, eff∅,
eff∅, AntiCan∅,
ChemoSen↑, radioP↑, QoL↑, Risk↓, *selenoP↑, TumCP↓, Inflam↓, ChemoSen↑, TumCCA↑, Apoptosis↑, angioG↓, Dose⇅, ROS↑, eff↑, Risk↓, eff∅, CSCs↓, ROS↑,
AntiCan↑, Dose↝, Risk↓, TumCP↓, Inflam↓, eff∅,
Dose∅, TumMeta↑, eff∅, Piezo1↑, COX2↑, RANKL↓, TumCG∅, tumCV∅, TumCI↓,
Showing Research Papers: 1 to 13 of 13
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 13
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress ⓘ
hyperG↓, 1, ROS↑, 4,
Metal & Cofactor Biology ⓘ
KLF5↓, 1,
Mitochondria & Bioenergetics ⓘ
mtDam↑, 1,
Core Metabolism/Glycolysis ⓘ
ALAT↓, 1,
Cell Death ⓘ
Akt↓, 1, Akt↑, 2, p‑Akt↓, 1, Apoptosis↑, 3, ASK1↑, 1, BAX↑, 1, Bax:Bcl2↑, 1, BIM↑, 1, Casp↑, 1, Casp3↑, 2, DR5↑, 1, Proteasome↓, 1, TumCD↑, 1,
Transcription & Epigenetics ⓘ
other↑, 1, tumCV∅, 1,
Protein Folding & ER Stress ⓘ
CHOP↑, 1, ER Stress↑, 2, XBP-1↑, 1,
DNA Damage & Repair ⓘ
P53↑, 2, cl‑PARP↑, 1,
Cell Cycle & Senescence ⓘ
CDK1↓, 1, CDK4↑, 2, P21↑, 1, TumCCA↑, 3,
Proliferation, Differentiation & Cell State ⓘ
CSCs↓, 1, p‑ERK↑, 1, FOXO3↓, 1, GSK‐3β↓, 1, p‑GSK‐3β↑, 1, HDAC↓, 1, mTOR↑, 2, Nanog↓, 1, OCT4↓, 1, PI3K↑, 2, Piezo1↑, 1, PTEN↑, 1, p‑PTEN↓, 1, TumCG↓, 1, TumCG∅, 1,
Migration ⓘ
p‑FAK↑, 1, KLF2↓, 1, MMPs↓, 1, PKA↓, 1, TumCI↓, 1, TumCP↓, 3, TumMeta↓, 1, TumMeta↑, 1,
Angiogenesis & Vasculature ⓘ
angioG↓, 2, ATF4↑, 1, VEGF↓, 1,
Immune & Inflammatory Signaling ⓘ
COX2↓, 1, COX2↑, 1, IL10↑, 1, IL2↑, 1, Inflam↓, 2, NF-kB↓, 2, PSA↓, 1,
Cellular Microenvironment ⓘ
Temp↓, 1,
Hormonal & Nuclear Receptors ⓘ
AR↓, 1, CDK6↑, 2, RANKL↓, 1,
Drug Metabolism & Resistance ⓘ
BioAv↝, 1, ChemoSen↑, 2, Dose?, 1, Dose⇅, 1, Dose↝, 3, Dose∅, 1, eff↓, 1, eff↑, 9, eff∅, 13,
Clinical Biomarkers ⓘ
ALAT↓, 1, ALP↓, 1, AR↓, 1, AST↓, 1, BG↓, 1, PSA↓, 1,
Functional Outcomes ⓘ
AntiCan↑, 1, AntiCan∅, 1, CardioT↑, 1, ChemoSideEff↓, 1, MusCon↓, 1, QoL↑, 1, radioP↑, 1, Risk↓, 4, toxicity↝, 1, TumVol↓, 2,
Total Targets: 91
Pathway results for Effect on Normal Cells:
Redox & Oxidative Stress ⓘ
selenoP↑, 1,
DNA Damage & Repair ⓘ
DNArepair↑, 1,
Drug Metabolism & Resistance ⓘ
BioAv↝, 1, Dose↝, 1,
Clinical Biomarkers ⓘ
BP↓, 1,
Functional Outcomes ⓘ
cardioP↑, 1, cognitive↑, 1, memory↑, 1,
Total Targets: 8
Scientific Paper Hit Count for: eff, efficacy
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:961 State#:% Dir#:6
wNotes=0 sortOrder:rid,rpid
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