eff Cancer Research Results

eff, efficacy: Click to Expand ⟱
Source:
Type:
Power to enhance an anti cancer effect


Scientific Papers found: Click to Expand⟱
2013- CAP,    Capsaicin, a component of red peppers, inhibits the growth of androgen-independent, p53 mutant prostate cancer cells
- in-vitro, Pca, PC3 - in-vitro, Pca, LNCaP - in-vitro, Pca, DU145 - in-vivo, NA, NA
TumCP↓, P53↑, P21↑, BAX↑, PSA↓, AR↓, NF-kB↓, Proteasome↓, TumVol↓, eff∅,
5917- Cats,    Uncaria tomentosa for Reducing Side Effects Caused by Chemotherapy in CRC Patients: Clinical Trial
- Trial, CRC, NA
Dose↝, *DNArepair↑, toxicity↝, BioAv↝, eff∅,
5960- CEL,    Phase II, Randomized, Placebo-Controlled Trial of Neoadjuvant Celecoxib in Men With Clinically Localized Prostate Cancer: Evaluation of Drug-Specific Biomarkers
- Trial, Pca, NA
eff∅, Dose↝, CardioT↑,
6098- Chol,    Choline
- Review, Nor, NA - Review, AD, NA
*BioAv↝, *Dose↝, *cardioP↑, *BP↓, *cognitive↑, *memory↑, eff∅,
1860- dietFMD,  Chemo,    Fasting-mimicking diet blocks triple-negative breast cancer and cancer stem cell escape
- in-vitro, BC, SUM159 - in-vitro, BC, 4T1
PI3K↑, Akt↑, mTOR↑, CDK4↑, CDK6↑, hyperG↓, TumCG↓, TumVol↓, Casp3↑, BG↓, eff↑, eff∅, PKA↓, KLF5↓, p‑GSK‐3β↑, Nanog↓, OCT4↓, KLF2↓, eff↑, ROS↑, BIM↑, ASK1↑, PI3K↑, Akt↑, mTOR↑, CDK1↓, CDK4↑, CDK6↑, eff↑,
5489- EP,    Electroporation and cell killing by milli- to nanosecond pulses and avoiding neuromuscular stimulation in cancer ablation
- in-vitro, Colon, NA
eff↑, TumCD↑, MusCon↓, Temp↓, eff↑, eff↓, eff↑, eff∅, other↑,
2855- FIS,    Fisetin Induces Apoptosis Through p53-Mediated Up-Regulation of DR5 Expression in Human Renal Carcinoma Caki Cells
- in-vitro, RCC, Caki-1
TumCCA↑, cl‑PARP↑, Apoptosis↑, Casp↑, P53↑, DR5↑, CHOP↑, ROS↑, ER Stress↑, ATF4↑, XBP-1↑, eff∅,
1660- PBG,    Emerging Adjuvant Therapy for Cancer: Propolis and its Constituents
- Review, Var, NA
MMPs↓, angioG↓, TumMeta↓, TumCCA↑, Apoptosis↑, ChemoSideEff↓, eff∅, HDAC↓, PTEN↑, p‑PTEN↓, p‑Akt↓, Casp3↑, p‑ERK↑, p‑FAK↑, Dose?, Akt↓, GSK‐3β↓, FOXO3↓, eff↑, IL2↑, IL10↑, NF-kB↓, VEGF↓, mtDam↑, ER Stress↑, AST↓, ALAT↓, ALP↓, COX2↓, eff↑, Bax:Bcl2↑,
1702- Se,    Supplemental Selenium May Decrease Ovarian Cancer Risk in African-American Women
- Human, Ovarian, NA
Risk↓, eff∅,
1687- SSE,    Selenium for preventing cancer
- Analysis, Var, NA
eff∅, AntiCan∅,
4739- SSE,  Chemo,  Rad,    Therapeutic Benefits of Selenium in Hematological Malignancies
- Review, Var, NA
ChemoSen↑, radioP↑, QoL↑, Risk↓, *selenoP↑, TumCP↓, Inflam↓, ChemoSen↑, TumCCA↑, Apoptosis↑, angioG↓, Dose⇅, ROS↑, eff↑, Risk↓, eff∅, CSCs↓, ROS↑,
1739- VitD3,    Effect of Vitamin D3 Supplements on Development of Advanced Cancer
- Trial, Var, NA
AntiCan↑, Dose↝, Risk↓, TumCP↓, Inflam↓, eff∅,
1755- WBV,    Reduction of breast cancer extravasation via vibration activated osteocyte regulation
Dose∅, TumMeta↑, eff∅, Piezo1↑, COX2↑, RANKL↓, TumCG∅, tumCV∅, TumCI↓,

Showing Research Papers: 1 to 13 of 13

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 13

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress

hyperG↓, 1,   ROS↑, 4,  

Metal & Cofactor Biology

KLF5↓, 1,  

Mitochondria & Bioenergetics

mtDam↑, 1,  

Core Metabolism/Glycolysis

ALAT↓, 1,  

Cell Death

Akt↓, 1,   Akt↑, 2,   p‑Akt↓, 1,   Apoptosis↑, 3,   ASK1↑, 1,   BAX↑, 1,   Bax:Bcl2↑, 1,   BIM↑, 1,   Casp↑, 1,   Casp3↑, 2,   DR5↑, 1,   Proteasome↓, 1,   TumCD↑, 1,  

Transcription & Epigenetics

other↑, 1,   tumCV∅, 1,  

Protein Folding & ER Stress

CHOP↑, 1,   ER Stress↑, 2,   XBP-1↑, 1,  

DNA Damage & Repair

P53↑, 2,   cl‑PARP↑, 1,  

Cell Cycle & Senescence

CDK1↓, 1,   CDK4↑, 2,   P21↑, 1,   TumCCA↑, 3,  

Proliferation, Differentiation & Cell State

CSCs↓, 1,   p‑ERK↑, 1,   FOXO3↓, 1,   GSK‐3β↓, 1,   p‑GSK‐3β↑, 1,   HDAC↓, 1,   mTOR↑, 2,   Nanog↓, 1,   OCT4↓, 1,   PI3K↑, 2,   Piezo1↑, 1,   PTEN↑, 1,   p‑PTEN↓, 1,   TumCG↓, 1,   TumCG∅, 1,  

Migration

p‑FAK↑, 1,   KLF2↓, 1,   MMPs↓, 1,   PKA↓, 1,   TumCI↓, 1,   TumCP↓, 3,   TumMeta↓, 1,   TumMeta↑, 1,  

Angiogenesis & Vasculature

angioG↓, 2,   ATF4↑, 1,   VEGF↓, 1,  

Immune & Inflammatory Signaling

COX2↓, 1,   COX2↑, 1,   IL10↑, 1,   IL2↑, 1,   Inflam↓, 2,   NF-kB↓, 2,   PSA↓, 1,  

Cellular Microenvironment

Temp↓, 1,  

Hormonal & Nuclear Receptors

AR↓, 1,   CDK6↑, 2,   RANKL↓, 1,  

Drug Metabolism & Resistance

BioAv↝, 1,   ChemoSen↑, 2,   Dose?, 1,   Dose⇅, 1,   Dose↝, 3,   Dose∅, 1,   eff↓, 1,   eff↑, 9,   eff∅, 13,  

Clinical Biomarkers

ALAT↓, 1,   ALP↓, 1,   AR↓, 1,   AST↓, 1,   BG↓, 1,   PSA↓, 1,  

Functional Outcomes

AntiCan↑, 1,   AntiCan∅, 1,   CardioT↑, 1,   ChemoSideEff↓, 1,   MusCon↓, 1,   QoL↑, 1,   radioP↑, 1,   Risk↓, 4,   toxicity↝, 1,   TumVol↓, 2,  
Total Targets: 91

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress

selenoP↑, 1,  

DNA Damage & Repair

DNArepair↑, 1,  

Drug Metabolism & Resistance

BioAv↝, 1,   Dose↝, 1,  

Clinical Biomarkers

BP↓, 1,  

Functional Outcomes

cardioP↑, 1,   cognitive↑, 1,   memory↑, 1,  
Total Targets: 8

Scientific Paper Hit Count for: eff, efficacy
2 Chemotherapy
2 Selenite (Sodium)
1 Capsaicin
1 Cat’s Claw
1 Celecoxib
1 Choline
1 diet FMD Fasting Mimicking Diet
1 Electrical Pulses
1 Fisetin
1 Propolis -bee glue
1 Selenium
1 Radiotherapy/Radiation
1 Vitamin D3
1 Whole Body Vibration
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:961  State#:%  Dir#:6
wNotes=0 sortOrder:rid,rpid

 

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