| Features: Therapy |
| Regular physical activity has been shown to influence cancer risk, progression, and survivorship. While exercise is not a cure for cancer, extensive research indicates that it can help reduce the risk of developing certain types of cancer and improve outcomes and quality of life for those diagnosed. -Lowering the levels of hormones levels. -Preventing high blood levels of insulin. -Regular physical activity leads to decreased levels of inflammatory markers (such as C-reactive protein and interleukin-6). -Improving immune system function (enhancing the circulation of immune cells, including natural killer cells, T lymphocytes, and macrophages) -Reducing the time it takes for food to travel through the digestive system. -Helping to prevent obesity, which is a risk factor for many cancers. -Exercise promotes the upregulation of antioxidant defenses. Exercise simultaneously modulates multiple core cancer drivers: ↓ Insulin / IGF-1 signaling ↓ Chronic inflammation (IL-6, TNF-α baseline) ↑ Immune surveillance (NK cells, CD8⁺ T cells) ↑ Mitochondrial function and mitophagy ↓ Estrogen and androgen bioavailability ↑ Circadian stability ↓ Visceral adiposity (key endocrine organ) No supplement or single molecule does this breadth of work. |
| 3876- | Carno, | Ex, | Swimming exercise versus L-carnosine supplementation for Alzheimer’s dementia in rats: implication of circulating and hippocampal FNDC5/irisin |
| - | in-vivo, | AD, | NA |
| - | Trial, | Colon, | NA |
| 2143- | Ex, | The association between physical activity and bladder cancer: systematic review and meta-analysis |
| - | Review, | Bladder, | NA |
| 4174- | Ex, | Exercise-Mediated Neurogenesis in the Hippocampus via BDNF |
| - | Review, | NA, | NA |
| 4155- | Ex, | Prior regular exercise reverses the decreased effects of sleep deprivation on brain-derived neurotrophic factor levels in the hippocampus of ovariectomized female rats |
| - | in-vivo, | AD, | NA |
| 4145- | Ex, | Effects of different physical activities on brain-derived neurotrophic factor: A systematic review and bayesian network meta-analysis |
| - | Review, | AD, | NA |
| 4144- | Ex, | Exploring the impact of exercise-induced BDNF on neuroplasticity in neurodegenerative and neuropsychiatric conditions |
| - | Review, | AD, | NA |
| 4143- | Ex, | Brain-Derived Neurotrophic Factor: A Connecting Link Between Nutrition, Lifestyle, and Alzheimer’s Disease |
| - | Review, | AD, | NA |
| 4142- | Ex, | Mechanisms of the Beneficial Effects of Exercise on Brain-Derived Neurotrophic Factor Expression in Alzheimer’s Disease |
| - | Review, | AD, | NA |
| 4141- | Ex, | Effects of exercise on brain-derived neurotrophic factor in Alzheimer's disease models: A systematic review and meta-analysis |
| - | Review, | AD, | NA |
| 4140- | Ex, | Experimental and clinical evidence of physical exercise on BDNF and cognitive function: A comprehensive review from molecular basis to therapy |
| - | Review, | AD, | NA |
| 4139- | Ex, | Impact of physical exercise on the regulation of brain-derived neurotrophic factor in people with neurodegenerative diseases |
| - | Review, | AD, | NA |
| 4138- | Ex, | Relationship Between Exercise and Alzheimer’s Disease: A Narrative Literature Review |
| - | Review, | AD, | NA |
| 4137- | Ex, | The impact of exercise on patients with dementia |
| - | Trial, | AD, | NA |
| 3985- | Ex, | The combined effect of physical activity and fruit and vegetable intake on decreasing cognitive decline in older Taiwanese adults |
| - | Study, | AD, | NA |
| 2153- | Ex, | The Impact of Exercise on Cancer Mortality, Recurrence, and Treatment-Related Adverse Effects |
| - | Review, | Var, | NA |
| 2151- | Ex, | The effects of physical activity on overall survival among advanced cancer patients: a systematic review and meta-analysis |
| - | Review, | Var, | NA |
| 2150- | Ex, | Roles and molecular mechanisms of physical exercise in cancer prevention and treatment |
| - | Review, | Var, | NA |
| 2149- | Ex, | Physical activity and exercise training in cancer patients |
| - | Analysis, | Var, | NA |
| 2148- | Ex, | Effects of Exercise on Cancer Treatment Efficacy: A Systematic Review of Preclinical and Clinical Studies |
| - | Review, | Var, | NA |
| 2147- | Ex, | The association between physical activity and gastroesophageal cancer: systematic review and meta-analysis |
| - | Review, | GC, | NA |
| 2146- | Ex, | A systematic review and meta-analysis of physical activity and endometrial cancer risk |
| - | Review, | Endo, | NA |
| 2145- | Ex, | Leisure time physical activity and cancer risk: evaluation of the WHO's recommendation based on 126 high-quality epidemiological studies |
| - | Analysis, | Var, | NA |
| 2144- | Ex, | Physical activity, hormone replacement therapy and breast cancer risk: A meta-analysis of prospective studies |
| - | Analysis, | NA, | NA |
| 4107- | FLS, | Ex, | Combined effects of aerobic exercise and 40-Hz light flicker exposure on early cognitive impairments in Alzheimer's disease of 3×Tg mice |
| - | in-vivo, | AD, | NA |
| 3789- | UA, | Ex, | Combined Ursolic Acid and Resistance/Endurance Training Improve Type 3 Diabetes Biomarkers-Related Memory Deficits in Hippocampus of Aged Male Wistar Rats |
| - | in-vivo, | AD, | NA |
| 4183- | VitD3, | Ex, | Combined Exercise and Vitamin D on Brain-Derived Neurotrophic Factor |
| - | Review, | NA, | NA |
| 1753- | WBV, | Ex, | Physical Exercise with or without Whole-Body Vibration in Breast Cancer Patients Suffering from Aromatase Inhibitor—Induced Musculoskeletal Symptoms: A Pilot Randomized Clinical Study |
| - | Trial, | BC, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
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