BBB Cancer Research Results

BBB, Blood-Brain Barrier Permeability: Click to Expand ⟱
Source:
Type:
Blood-Brain Barrier(BBB) is a term often used regarding if a product has the ability to cross the BBB.


Scientific Papers found: Click to Expand⟱
6462- 1,8-Cin,    Modes of Action of 1,8-Cineol in Infections and Inflammation
- Review, Var, NA - Review, AD, NA
*BioAv↑, *BBB↑, *AntiViral↑, *Bacteria↓, *AntiFungal↑, *Inflam↓, *BioAv↑, *MUC2↓, *MUC19↓, *NF-kB↓, *ICAM-1↓, *VCAM-1↓, DNAdam↑, *lipid-P↓, *PGE2↓, *IL4↓, *IL6↓, *IL1β↓, *IL6↓, Synergy↑, TGF-β↓, fascin↓, VEGF↓, MMP9↓, *MAPK↓, *ERK↓, JNK↓, Wnt↓, β-catenin/ZEB1↓, GSK‐3β↑, *neuroP↑, *GSK‐3β↓, *AGEs↓, *BBB↑, *NLRP3↓,
3537- 5-HTP,    5-Hydroxytryptophan: a clinically-effective serotonin precursor
- Review, Nor, NA
*5HT↑, *BioAv↑, *BBB↑,
3538- 5-HTP,    Oral Administration of 5-Hydroxytryptophan Restores Gut Microbiota Dysbiosis in a Mouse Model of Depression
- in-vivo, Nor, NA
*GutMicro↑, *BBB↑, *5HT↑, *Weight↓,
5288- 5-HTP,    The Impact of 5-Hydroxytryptophan Supplementation on Cognitive Function and Mood in Singapore Older Adults: A Randomized Controlled Trial
- Trial, AD, NA
*5HT↑, *cognitive↑, *BBB↑, *Mood↑,
5312- acet,    Analgesic Effect of Acetaminophen: A Review of Known and Novel Mechanisms of Action
- Review, Nor, NA
*COX1↓, *other?, *BBB↑, TRPV1↑,
3864- ACNs,    Anthocyanins Potentially Contribute to Defense against Alzheimer’s Disease
- Review, AD, NA
*antiOx↑, *Aβ↓, *ROS↓, *cognitive↑, *APP↓, *BBB↑, *Ca+2↓, *ATP↑, *BACE/β-secretase↓, *p‑NF-kB↓, *TNF-α↓, *iNOS↓,
4549- AgNPs,    Silver nanoparticles: Synthesis, medical applications and biosafety
- Review, Var, NA - Review, Diabetic, NA
ROS↑, eff↑, other↝, DNAdam↑, EPR↑, eff↑, eff↑, TumMeta↓, angioG↓, *Bacteria↓, *eff↑, *AntiViral↑, *AntiFungal↑, eff↑, eff↑, TumCP↓, tumCV↓, P53↝, HIF-1↓, TumCCA↑, lipid-P↑, ATP↓, Cyt‑c↑, MMPs↓, PI3K↓, Akt↓, *Wound Healing↑, *Inflam↓, *Bone Healing↑, *glucose↓, *AntiDiabetic↑, *BBB↑,
4583- AgNPs,    Metal-Based Nanoparticles for Cardiovascular Diseases
- Review, CardioV, NA
RadioS↑, *ROS↑, *BBB↝,
4368- AgNPs,    Silver nanoparticles crossing through and distribution in the blood-brain barrier in vitro
- in-vitro, Nor, NA
*BBB↑,
306- AgNPs,    Cancer Therapy by Silver Nanoparticles: Fiction or Reality?
- Analysis, Var, NA
EPR↝, ROS↑, IL1↑, IL8↑, ER Stress↑, MMP9↑, MMP↓, Cyt‑c↑, Apoptosis↑, Hif1a↑, BBB↑, GutMicro↝, eff↑, eff↑, RadioS↑,
2660- AL,    Allicin: A review of its important pharmacological activities
- Review, AD, NA - Review, Var, NA - Review, Park, NA - Review, Stroke, NA
*Inflam↓, AntiCan↑, *antiOx↑, *cardioP↑, *hepatoP↑, *BBB↑, *Half-Life↝, *H2S↑, *BP↓, *neuroP↑, *cognitive↑, *neuroP↑, *ROS↓, *GutMicro↑, *LDH↓, *ROS↓, *lipid-P↓, *antiOx↑, *other↑, *PI3K↓, *Akt↓, *NF-kB↓, *NO↓, *iNOS↓, *PGE2↓, *COX2/PTGS2↓, *IL6↓, *TNF-α↓, *MPO↓, *Synergy↑, *NRF2↑, *Keap1↓, *TBARS↓, *creat↓, *LDH↓, *AST↓, *ALAT↓, *MDA↓, *SOD↑, *GSH↑, *GSTs↑, *memory↑, chemoP↑, IL8↓, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, Casp12↑, p38↑, Fas↑, P53↑, P21↑, CHK1↓, CycB/CCNB1↓, GSH↓, ROS↑, TumCCA↑, Hif1a↓, Bcl-2↓, VEGF↓, TumCMig↓, STAT3↓, VEGFR2/KDR/Flk1↓, p‑FAK↓,
3269- ALA,    Sulfur-containing therapeutics in the treatment of Alzheimer’s disease
- Review, AD, NA
*AChE↓, *GlucoseCon↑, *ACC↑, *GSH↑, *Aβ↓, *Catalase↑, *GSR↑, *GSTs↑, *NADPH↑, *NQO1↑, *iNOS↓, *NF-kB↓, *lipid-P↓, *BBB↑, *memory↑, *cognitive↑, *antiOx↑, *Inflam↓,
3271- ALA,    Decrypting the potential role of α-lipoic acid in Alzheimer's disease
- Review, AD, NA
*antiOx↑, *memory↑, *neuroP↑, *Inflam↓, *IronCh↑, *NRF2↑, *BBB↑, *GlucoseCon↑, *Ach↑, *ROS↓, *p‑tau↓, *Aβ↓, *cognitive↑, *Hif1a↑, *Ca+2↓, *GLUT3↑, *GLUT4↑, *HO-1↑, *VEGF↑, *PDKs↓, *PDH↑, *VCAM-1↓, *GSH↑, *NRF2↑, *hepatoP↑, *ChAT↑,
3272- ALA,    Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential
- Review, AD, NA
*antiOx↑, *glucose↑, *eNOS↑, *NRF2↑, *MMP9↓, *VCAM-1↓, *NF-kB↓, *cardioP↑, *cognitive↑, *eff↓, *BBB↑, *IronCh↑, *GSH↑, *PKCδ↑, *ERK↑, *p38↑, *MAPK↑, *PI3K↑, *Akt↑, *PTEN↓, *AMPK↑, *GLUT4↑, *GLUT1↑, *Inflam↓,
3284- ALA,    Alpha-Lipoic Acid Mediates Clearance of Iron Accumulation by Regulating Iron Metabolism in a Parkinson's Disease Model Induced by 6-OHDA
- vitro+vivo, Park, NA
*antiOx↑, *IronCh↑, *neuroP↑, *ROS↓, *Iron↓, *BBB↑, *motorD↑, *GSH↑,
3444- ALA,    Alpha-Lipoic Acid Nootropic Review: Benefits, Use, Dosage & Side Effects
- Review, Nor, NA
*BBB↑, *cognitive↑, *neuroP↑, *antiOx↑,
3542- ALA,    Chelation: Harnessing and Enhancing Heavy Metal Detoxification—A Review
- Review, Var, NA
*antiOx↑, *VitE↑, *VitC↑, *GSH↑, *IronCh↑, *BioAv↑, *BBB↑,
3546- ALA,    Cognitive and Mood Effect of Alpha-Lipoic Acid Supplementation in a Nonclinical Elder Sample: An Open-Label Pilot Study
- Study, AD, NA
*antiOx↑, *ROS↓, *cognitive∅, *lipid-P↓, *memory↑, *ChAT↑, *Acetyl-CoA↑, *Aβ↓, *BioAv↑, *BBB↑, *toxicity∅,
3548- ALA,    How Alpha Linolenic Acid May Sustain Blood–Brain Barrier Integrity and Boost Brain Resilience against Alzheimer’s Disease
- Review, AD, NA
*BBB↑, *other↑, *other↑, *DHA↑, *neuroP↑, *ROS↓, *other?,
3549- ALA,    Important roles of linoleic acid and α-linolenic acid in regulating cognitive impairment and neuropsychiatric issues in metabolic-related dementia
- Review, AD, NA
*Inflam↓, *other↝, *other↝, *neuroP↑, *BioAv↝, *adiP↑, *BBB↑, *Casp6↓, *Casp9↓, *TNF-α↓, *IL6↓, *IL1β↓, *ROS↓, *NO↓, *iNOS↓, *COX2/PTGS2↓, *JNK↓, *p‑NF-kB↓, *Aβ↓, *BP↓, *memory↑, *cAMP↑, *ERK↑, *Akt↑, cognitive?,
3550- ALA,    Mitochondrial Dysfunction and Alpha-Lipoic Acid: Beneficial or Harmful in Alzheimer's Disease?
- Review, AD, NA
*antiOx↑, *Inflam↓, *PGE2↓, *COX2/PTGS2↓, *iNOS↓, *TNF-α↓, *IL1β↓, *IL6↓, *BioAv↓, *Ach↑, *ROS↓, *cognitive↑, *neuroP↑, *BBB↑, *Half-Life↓, *BioAv↑, *Casp3↓, *Casp9↓, *ChAT↑, *cognitive↑, *eff↑, *cAMP↑, *IL2↓, *INF-γ↓, *TNF-α↓, *SIRT1↑, *SOD↑, *GPx↑, *MDA↓, *NRF2↑,
3544- ALA,    Alpha lipoic acid for dementia
- Review, AD, NA
*antiOx↑, *BBB↑, *VitC↑, *VitE↑, *GSH↑, *IronCh↑, *neuroP↑, *NO↓, *cognitive↑, *AntiAge↑, *memory↑, *ROS↓,
3541- ALA,    Insights on alpha lipoic and dihydrolipoic acids as promising scavengers of oxidative stress and possible chelators in mercury toxicology
- Review, Var, NA
*antiOx↑, *IronCh↑, *GSH↑, *BBB↑, Apoptosis↑, MMP↓, ROS↑, lipid-P↑, PARP1↑, Casp3↑, Casp9↑, *NRF2↑, *GSH↑, *ROS↓, RenoP↑, ChemoSen↑, *BG↓,
3539- ALA,    Alpha-lipoic acid as a dietary supplement: Molecular mechanisms and therapeutic potential
- Review, AD, NA
*ROS↓, *IronCh↑, *GSH↑, *antiOx↑, *NRF2↑, *MMP9↓, *VCAM-1↓, *NF-kB↓, *cognitive↑, *Inflam↓, *BioAv↝, *BioAv↝, *BBB↑, *H2O2∅, *neuroP↑, *PKCδ↑, *ERK↑, *MAPK↑, *PI3K↑, *Akt↑, *PTEN↓, *AMPK↑, *GLUT4↑, *GlucoseCon↑, *BP↝, *Synergy↑, *ICAM-1↓, *VCAM-1↓, *Dose↝,
5317- ALC,    Acetyl-L-carnitine permeability across the blood-brain barrier and involvement of carnitine transporter OCTN2
- in-vivo, Nor, NA
*BBB↝,
5358- almon,    Experimental Study of Almonertinib Crossing the Blood-Brain Barrier in EGFR-Mutant NSCLC Brain Metastasis and Spinal Cord Metastasis Models
- vitro+vivo, NSCLC, NA
TumMeta↓, BBB↑, EGFR↓,
5360- almon,  BEV,    Case report: Almonertinib in combination with bevacizumab for leptomeningeal metastases from epidermal growth factor receptor-mutation non-small cell lung cancer: Case series
- Case Report, NSCLC, NA
BBB↑, Dose↝, eff↓, OS↑,
3887- Api,    The flavonoid apigenin protects brain neurovascular coupling against amyloid-β₂₅₋₃₅-induced toxicity in mice
- in-vivo, AD, NA
*Inflam↓, *ROS↓, *Aβ↓, *memory↑, *AChE↓, *Ach↑, *Dose↑, *BDNF↑, *TrkB↑, *p‑CREB↑, *BBB↑, *Ca+2?,
4280- Api,    Protective effects of apigenin in neurodegeneration: An update on the potential mechanisms
- Review, AD, NA - Review, Park, NA
*neuroP↑, *antiOx↑, *ROS↓, *Inflam↓, *TNF-α↓, *IL1β↓, *PI3K↑, *Akt↑, *BBB↑, *NRF2↑, *SOD↑, *GPx↑, *MAPK↓, *Catalase↑, *HO-1↑, *COX2/PTGS2↓, *PGE2↓, *PPARγ↑, *TLR4↓, *GSK‐3β↓, *Aβ↓, *NLRP3↓, *BDNF↑, *TrkB↑, *GABA↑, *AChE↓, *Ach↑, *5HT↑, *cognitive↑, *MAOA↓,
4279- Api,    The Beneficial Role of Apigenin against Cognitive and Neurobehavioural Dysfunction: A Systematic Review of Preclinical Investigations
- Review, AD, NA
*antiOx↑, *Inflam↓, *BBB↑, *5HT↑, *CREB↑, *BDNF↑, *memory↑, *motorD↑, *Mood↑, *cognitive↑, *ROS↓,
3822- Aroma,    Aromatherapy in the treatment of Alzheimer's disease: A systematic review
- Review, AD, NA
*cognitive↑, *other↑, *other↓, *BioAv↑, *BBB?,
4303- Ash,    Ashwagandha (Withania somnifera)—Current Research on the Health-Promoting Activities: A Narrative Review
- Review, AD, NA
*neuroP↑, *Sleep↑, *Inflam↓, *cardioP↑, *cognitive↑, *Aβ↓, *TNF-α↓, *IL1β↓, *IL6↓, *MCP1/CCL2↓, *lipid-P↓, *tau↓, *ROS↓, *BBB↑, *AChE↓, *GSH↑, *GSTs↑, *GSR↑, *GPx↑, *SOD↑, *Catalase↑, ChemoSen↑, *Strength↑,
5425- ASTX,    Multiple roles of fucoxanthin and astaxanthin against Alzheimer's disease: Their pharmacological potential and therapeutic insights
- in-vivo, AD, NA
*neuroP↑, *antiOx↑, *Inflam↑, *AChE↓, *BACE/β-secretase↓, *MAOA↓, *Aβ↓, *memory↑, *MDA↓, *SOD↑, *NRF2↑, *HO-1↑, *NF-kB↓, *GSK‐3β↓, *ChAT↑, *iNOS↓, *ROS↓, *BBB↑,
5508- Ba,    Neuroprotective effects of baicalin and baicalein on the central nervous system and the underlying mechanisms
- Review, Stroke, NA - Review, Park, NA - Review, AD, NA
*neuroP↑, *antiOx↑, *Inflam↓, *BioAv↝, *BioAv↑, *Half-Life↝, *TLR4↓, *NF-kB↓, *iNOS↓, *COX2/PTGS2↓, *TNF-α↓, *12LOX↓, *NLRP3↓, *ROS↓, *IL1β↓, *IL6↓, *GSK‐3β↓, *NRF2↑, *BBB↑, *SOD↑, *GPx↑, *MDA↓,
2605- Ba,  BA,    Potential therapeutic effects of baicalin and baicalein
- Review, Var, NA - Review, Stroke, NA - Review, IBD, NA - Review, Arthritis, NA - Review, AD, NA - Review, Park, NA
cardioP↑, Inflam↓, cognitive↑, *hepatoP↑, *ROS?, *SOD↑, *GSH↑, *MMP↑, *GutMicro↑, ChemoSen↑, *TNF-α↓, *IL10↑, *IL6↓, *eff↑, *ROS↓, *COX2/PTGS2↓, *NF-kB↓, *STAT3↓, *PGE2↓, *MPO↓, *IL1β↓, *MMP2↓, *MMP9↓, *β-Amyloid↓, *neuroP↑, *Dose↝, *BioAv↝, *BioAv↝, *BBB↑, *BDNF↑,
2673- BBR,    Therapeutic potential and recent delivery systems of berberine: A wonder molecule
- Review, Var, NA
*BioAv↓, *Half-Life↓, *neuroP↑, BBB↑, toxicity↓,
3678- BBR,    Network pharmacology study on the mechanism of berberine in Alzheimer’s disease model
- Review, AD, NA
*APP↓, *PPARγ↑, *NF-kB↓, *Aβ↓, *cognitive↑, *antiOx↑, *Inflam↓, *Apoptosis↓, *BioAv↑, *BioAv↝, *BBB↑, *motorD↑, *NRF2↑, *HO-1↑, *ROS↓, *p‑Akt↑, *p‑ERK↑,
3680- BBR,    Network pharmacology reveals that Berberine may function against Alzheimer’s disease via the AKT signaling pathway
- in-vivo, AD, NA
*Akt↑, *neuroP↑, *p‑ERK↑, *Aβ↓, *Inflam↓, *ROS↓, *BioAv↑, *BBB↑, *Half-Life↝, *memory↑, *cognitive↑, *HSP90↑, *APP↓, *mTOR↓, *P70S6K↓, *CD31/PECAM-1↑, *VEGF↑, *N-cadherin↑, *Apoptosis↓,
3677- BBR,    Berberine: A Potential Multipotent Natural Product to Combat Alzheimer’s Disease
- Review, AD, NA
*antiOx↑, *AChE↓, *BChE↓, *MAOA↓, *Aβ↓, *LDL↓, *ROS↓, *RNS↓, *lipid-P↓, *Dose↝, *MAOB↓, *memory↑, *toxicity↓, *BBB↑,
6503- BCP,    The Potential Therapeutic Role of Beta-Caryophyllene as a Chemosensitizer and an Inhibitor of Angiogenesis in Cancer
- Review, Var, NA
ChemoSen↑, angioG↓, TumCI↓, TumMeta↓, ROS↑, *ROS↓, chemoP↑, CB2 / CNR2↑, Inflam↓, AntiTum↑, *BioAv↑, *BBB↑, Apoptosis↑, TumCP↑, TumCCA↑, RadioS↑, DNArepair↓, ROS↑, STAT3↓, *BioEnh↑, Pain↓, AntiBio↓, ROS↑, Dose↝, NF-kB↓, MAPK↓, TNF-α↓, IL1β↓, IL6↓, cl‑PARP↑, Casp↑, BAX↑, Bcl-2↓, VEGF↓, VEGFR2/KDR/Flk1↓, MMP2↓, p‑p38↓, p‑ERK↓, EPR↑, P-gp/ABCB1↓, MRP1/ABCC1↓, *NRF2↑, *antiOx↑,
2731- BetA,    Betulinic Acid for Glioblastoma Treatment: Reality, Challenges and Perspectives
- Review, GBM, NA - Review, Park, NA - Review, AD, NA
BBB↑, *GSH↑, *Catalase↑, *motorD↑, *neuroP↑, *cognitive↑, *ROS↓, *antiOx↑, *Inflam↓, MMP↓, STAT3↓, NF-kB↓, Sp1/3/4↓, TOP1↓, EMT↓, Hif1a↓, VEGF↓, ChemoSen↑, RadioS↑, BioAv↓,
5561- betaCar,    Carotenoid Supplementation for Alleviating the Symptoms of Alzheimer’s Disease
- Review, AD, NA
*ROS↓, *cognitive↑, *BBB↑, *lipid-P↓, *eff↑,
5563- betaCar,    Carotenoid Supplementation for Alleviating the Symptoms of Alzheimer's Disease
- Review, AD, NA
*BBB↑, *lipid-P↓, *eff↑, *cognitive↑,
5692- BJ,    Seed oil of Brucea javanica induces apoptosis through the PI3K/Akt signaling pathway in acute lymphocytic leukemia Jurkat cells
- vitro+vivo, AML, NA
Apoptosis↑, Akt↓, P53↑, FOXO1↑, GSK‐3β↑, TumVol↓, QoL↑, BBB↑, OS↑, Dose↝, MMP↓, ROS↑, XIAP↑, Casp9↑, Casp8↑, Casp3↑, cl‑PARP↑, TumCCA↑,
5473- BM,    Bacopa monnieri: Preclinical and Clinical Evidence of Neuroactive Effects, Safety of Use and the Search for Improved Bioavailability
- in-vivo, AD, NA - in-vivo, Park, NA
*neuroP↑, *toxicity∅, *AChE↓, *ROS↓, *antiOx↑, *lipid-P↓, *cognitive↑, *memory↑, *Dose↝, *BioAv↓, *TumCCA↑, *BBB↝,
3697- BM,    Bacopa monnieri, a Neuroprotective Lead in Alzheimer Disease: A Review on Its Properties, Mechanisms of Action, and Preclinical and Clinical Studies
- Review, AD, NA
*ROS↓, *cognitive↑, *memory↑, *BBB↑, *P-gp/ABCB1↓, *CYP3A2↓,
5649- BNL,    Borneol, a novel agent that improves central nervous system drug delivery by enhancing blood–brain barrier permeability
- Review, Nor, NA
*BBB↑, *other↑, *P-gp/ABCB1↓, *toxicity⇅, *BioAv⇅, *Dose↑, *ABC↓, *MRP1/ABCC1↓, *5HT↑, *GABA↑, *Synergy↑,
5656- BNL,    Role of borneol as enhancer in drug formulation: A review
- Review, Nor, NA - Review, Stroke, NA - Review, AD, NA
*eff↑, BBB↑, ChemoSen↑, *Inflam↓, *NO↓, *TNF-α↓, *IL6↓, *Bacteria↓, *Synergy↑, *Aβ↓, *SOD↑, *neuroP↑, *EPR↑, toxicity↓, P-gp/ABCB1↓, Synergy↑, other↝,
5658- BNL,    Natural borneol is a novel chemosensitizer that enhances temozolomide-induced anticancer efficiency against human glioma by triggering mitochondrial dysfunction and reactive oxide species-mediated oxidative damage
- vitro+vivo, GBM, U251
ChemoSen↑, mt-Apoptosis↑, Casp↑, DNAdam↑, ROS↑, angioG↓, BBB↑, EPR↑, TumVol↓, TumW↓, BioEnh↑,
5659- BNL,    Borneol, a messenger agent, improves central nervous system drug delivery through enhancing blood–brain barrier permeability: a preclinical systematic review and meta-analysis
- Review, Var, NA
BBB↑, P-gp/ABCB1↓, MDR1↓, HIST1H3B?,

Showing Research Papers: 1 to 50 of 238
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 238

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 3,   antiOx⇅, 1,   Catalase↓, 2,   Catalase↑, 1,   GPx↑, 1,   GPx4↓, 1,   GSH↓, 3,   GSTs↑, 1,   HO-1↓, 1,   HO-1↑, 1,   Iron↑, 1,   Iron↝, 1,   lipid-P↑, 6,   MDA↓, 1,   MDA↑, 4,   NADH↓, 1,   NQO1↑, 1,   NRF2↓, 4,   NRF2↑, 3,   p66Shc↓, 1,   ROS↓, 5,   ROS↑, 31,   ROS⇅, 2,   mt-ROS↑, 3,   SOD↓, 2,   SOD↑, 1,   SOD2↓, 1,   Trx1↑, 1,   TrxR↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

CDC2↓, 1,   mitResp↓, 1,   mtDam↑, 3,   OCR↓, 2,   OCR↑, 1,   OXPHOS↑, 1,   mt-OXPHOS↑, 1,   PINK1↑, 1,   SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

5LO↓, 2,   AMPK↑, 2,   ATP↓, 1,   mt-ATP↓, 1,   ECAR↓, 1,   FASN↓, 1,   GlutMet↓, 1,   Glycolysis↓, 1,   GSK‐3β↑, 3,   lactateProd↓, 1,   NADPH↓, 1,   PDK1 / PDPK1↓, 1,   PDK3↑, 1,   SIRT1↓, 1,   SIRT1↑, 1,   TCA↓, 1,   Warburg↓, 1,  

Cell Death(tgid=5) ⓘ

APAF1↑, 1,   Apoptosis?, 1,   Apoptosis↓, 2,   Apoptosis↑, 22,   mt-Apoptosis↑, 1,   BAD↓, 1,   BAD↑, 1,   Bak↓, 1,   Bak↑, 2,   BAX↑, 10,   Bax:Bcl2↑, 1,   Bcl-2↓, 11,   Bcl-xL↓, 4,   BID↓, 1,   BID↑, 2,   BNIP3↑, 1,   Casp↑, 4,   cl‑Casp↑, 1,   Casp12↑, 1,   Casp3↓, 1,   Casp3↑, 17,   cl‑Casp3↑, 2,   proCasp3↓, 1,   Casp6↑, 1,   Casp7↑, 1,   Casp8↑, 7,   Casp9↑, 13,   cl‑Casp9↑, 1,   proCasp9↓, 1,   cFLIP↓, 2,   Cyt‑c↑, 17,   DR5↑, 4,   Fas↑, 2,   Ferroptosis↑, 2,   GranB/GZMB↝, 1,   ICD↑, 1,   iNOS↓, 1,   Mcl-1↑, 1,   MDM2↓, 1,   MOMP↑, 2,   p38↑, 2,   p‑p38↓, 1,   Perforin↝, 1,   survivin↓, 3,   TumCD↑, 1,   XIAP↓, 2,   XIAP↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 18,   p‑Akt↓, 5,   BRAF↓, 1,   cSrc↓, 1,   DYRK1B↓, 1,   EF-1α↓, 1,   EGFR↓, 3,   EGFR↑, 1,   p‑EGFR↓, 1,   ERK↓, 3,   p‑ERK↓, 2,   FOXD3↑, 1,   HER2/EBBR2↓, 1,   HGF/c-Met↓, 1,   IKKα↓, 1,   JAK1↓, 1,   JAK2↓, 3,   JNK↓, 1,   JNK↑, 2,   MAPK↓, 5,   MAPK↑, 1,   MEK↓, 1,   mTOR↓, 8,   p‑mTOR↓, 1,   PI3K↓, 12,   PTEN↑, 6,   c-Raf↓, 1,   RAS↓, 3,   Sp1/3/4↓, 1,   STAT3↓, 11,   p‑STAT3↓, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF4↑, 1,   cJun↑, 1,   cMyc↓, 3,   DNMTs↓, 2,   FOXM1↓, 1,   FOXO1↑, 1,   FOXO3↓, 1,   H3↓, 1,   H3↑, 1,   H4↑, 1,   HATs↑, 1,   HDAC↓, 2,   HDAC1↓, 1,   HIST1H3B?, 1,   miR-19b↓, 1,   Myc↓, 1,   OCT4↓, 1,   other↑, 2,   other↝, 3,   SOX2↓, 1,   SOX4↓, 1,   tumCV↓, 3,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   CHOP/DDIT3↑, 1,   cl‑CHOP/DDIT3↑, 1,   ER Stress↑, 5,   GRP78/BiP↑, 1,   HSP27↓, 1,   HSP90↓, 1,   PERK↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 2,   ATG7↑, 1,   Beclin-1/ATG6↑, 2,   CTSK↓, 1,   LC3II↑, 2,   MitoP↑, 1,   PARK2↑, 1,   TumAuto↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 6,   DNArepair↓, 1,   hTERT/TERT↓, 2,   P53?, 1,   P53↑, 11,   P53↝, 1,   PARP↑, 2,   cl‑PARP↑, 9,   PARP1↑, 1,   PCNA↓, 2,   Telomerase↓, 3,   TOP1↓, 3,   TOP2↓, 1,   TOP2↑, 1,   γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 1,   CDK1↑, 1,   CDK2↓, 5,   CDK4↓, 2,   CDK6↓, 1,   CHK1↓, 1,   cycA1/CCNA1↑, 1,   CycB/CCNB1↓, 4,   CycB/CCNB1↑, 2,   cycD1/CCND1↓, 3,   cycD1/CCND1↑, 1,   Ki-67↓, 2,   mitA↑, 1,   P21?, 1,   P21↑, 2,   p27/CDKN1B↑, 1,   p‑RB1↓, 1,   TubPol↓, 1,   TumCCA↓, 1,   TumCCA↑, 17,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

BMP7/OP1↓, 1,   BMPs↑, 1,   CD133↓, 2,   cFos↓, 1,   CSCs↓, 2,   Diff↑, 1,   EIF4E↓, 1,   FGF↓, 1,   Gli1↓, 3,   HH↓, 3,   IGF-1↓, 1,   Ki-67↓, 2,   mTORC1↓, 2,   Nanog↓, 1,   Nestin↓, 1,   NOTCH↓, 1,   NOTCH1↓, 1,   NOTCH1↑, 1,   NOTCH3↓, 1,   PTCH2↓, 1,   Shh↓, 1,   TumCG↓, 13,   TumCP↓, 14,   TumCP↑, 2,   Wnt↓, 6,  

Migration(tgid=13) ⓘ

Ca+2↑, 2,   Ca+2↝, 1,   E-cadherin↑, 3,   EMT↓, 8,   FAK↓, 1,   p‑FAK↓, 2,   fascin↓, 1,   MMP2↓, 9,   MMP7↓, 1,   MMP9↓, 11,   MMP9↑, 2,   MMPs↓, 6,   N-cadherin↓, 2,   Rac1↓, 1,   Rho↓, 1,   Rho↑, 1,   ROCK1↓, 1,   ROCK1↑, 1,   Snail↓, 2,   TGF-β↓, 1,   TIMP1↓, 1,   TIMP1↑, 1,   TIMP2↑, 1,   TRIB3↑, 1,   TumCI↓, 7,   TumCMig↓, 7,   TumMeta?, 1,   TumMeta↓, 10,   TumMeta↑, 2,   Twist↓, 3,   uPA↓, 4,   Vim↓, 2,   Zeb1↓, 1,   β-catenin/ZEB1↓, 6,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 16,   HIF-1↓, 1,   Hif1a↓, 10,   Hif1a↑, 1,   NO↝, 1,   VCAM-1↓, 1,   VEGF↓, 14,   VEGFR2/KDR/Flk1↓, 4,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 1,   BBB↑, 35,   BBB↝, 1,   BBB∅, 2,   EPR↑, 5,   EPR↝, 1,   GLUT1↓, 1,   MMP↓, 15,   MPT↑, 1,   TRPV1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CB2 / CNR2↑, 1,   COX2/PTGS2↓, 7,   CXCR2↓, 1,   CXCR4↓, 1,   DR4↑, 1,   ICAM-1↓, 2,   IL1↓, 1,   IL1↑, 1,   IL10↓, 1,   IL1β↓, 7,   IL2↑, 1,   IL6↓, 4,   IL8↓, 1,   IL8↑, 1,   Imm↑, 2,   Inflam↓, 7,   M1↑, 1,   M2 MC↑, 1,   NF-kB↓, 20,   NF-kB↑, 1,   NOD1↓, 1,   p65↓, 1,   PD-L1↓, 2,   PGE2↓, 3,   TNF-α↓, 7,  

Synaptic & Neurotransmission(tgid=18) ⓘ

SYN1↑, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ACTH↓, 1,   ADRB2↓, 1,   AR↓, 1,   GR↓, 1,   PPARγ↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 10,   BioAv↑, 11,   BioAv↝, 6,   BioEnh↑, 4,   ChemoSen?, 1,   ChemoSen↑, 25,   DDS↑, 1,   Dose↓, 1,   Dose↑, 1,   Dose↝, 9,   eff↓, 4,   eff↑, 21,   eff↝, 1,   Half-Life↓, 3,   Half-Life↑, 1,   Half-Life↝, 7,   MDR1↓, 3,   MRP1/ABCC1↓, 1,   P-gp/ABCB1↓, 6,   RadioS?, 1,   RadioS↑, 10,   selectivity↑, 8,   Synergy↑, 9,  

Clinical Biomarkers(tgid=22) ⓘ

AR↓, 1,   BRAF↓, 1,   CEA↓, 1,   EGFR↓, 3,   EGFR↑, 1,   p‑EGFR↓, 1,   FOXM1↓, 1,   HER2/EBBR2↓, 1,   hTERT/TERT↓, 2,   IL6↓, 4,   Myc↓, 1,   NOS2↑, 1,   PD-L1↓, 2,   TF-Ag↓, 1,   TRIB3↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 7,   AntiTum↑, 4,   cardioP↑, 4,   chemoP↑, 7,   chemoPv↑, 3,   cognitive?, 1,   cognitive↑, 2,   hepatoP↑, 1,   memory↑, 1,   neuroP↓, 1,   neuroP↑, 3,   Obesity↓, 1,   OS↑, 7,   Pain↓, 1,   QoL↑, 2,   RenoP↑, 1,   Risk↑, 1,   toxicity↓, 5,   toxicity↑, 2,   toxicity↝, 3,   toxicity∅, 2,   TumVol↓, 3,   TumW↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↓, 1,   GutMicro↑, 1,   GutMicro↝, 1,  
Total Targets: 381

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

NA↓, 1,   NA↝, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

4-HNE↓, 2,   antiOx↓, 3,   antiOx↑, 81,   mt-antiOx↑, 1,   ARE↑, 2,   Catalase↓, 1,   Catalase↑, 25,   Copper↓, 1,   CoQ10↑, 1,   Fenton↓, 2,   GPx↑, 18,   GPx4↑, 3,   GSH↑, 43,   GSR↓, 1,   GSR↑, 10,   GSTs↓, 3,   GSTs↑, 5,   H2O2↓, 2,   H2O2∅, 1,   HDL↑, 1,   HO-1↑, 25,   HO-2↓, 1,   hyperG↓, 1,   Iron↓, 4,   Keap1↓, 2,   Keap1↑, 2,   lipid-P↓, 31,   mt-lipid-P↓, 1,   MDA↓, 21,   MDA↑, 3,   MPO↓, 5,   NQO1↑, 7,   NQO1↝, 1,   NRF2↑, 50,   RNS↓, 4,   ROS?, 1,   ROS↓, 116,   ROS↑, 1,   SOD↓, 1,   SOD↑, 43,   mt-SOD↑, 1,   SOD1↑, 2,   SOD2↑, 1,   TAC↑, 4,   TBARS↓, 4,   Thiols↑, 1,   Trx↑, 1,   Trx1↑, 1,   TrxR↑, 1,   TrxR1↑, 1,   uricA↓, 1,   VitC↑, 3,   VitE↑, 3,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   Ferritin↑, 1,   FPN↑, 1,   IronCh↑, 16,   Mets↝, 1,   TfR1/CD71↓, 2,   TfR1/CD71↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↑, 1,   compII↑, 1,   compIII↑, 1,   compIV↑, 3,   compV↑, 1,   ETC↑, 3,   FIS1↓, 1,   mitResp↑, 1,   mtDam↓, 2,   OCR↑, 4,   PDH↑, 1,   PGC-1α↑, 5,   SIRT3↑, 4,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 2,   5LO↓, 2,   ACC↑, 1,   Acetyl-CoA↑, 1,   ACSL4↓, 2,   adiP↑, 2,   ALAT↓, 5,   AMPK↑, 10,   p‑AMPK↑, 1,   ATP↑, 10,   cAMP↑, 2,   DHA↑, 1,   ECAR↓, 1,   FAO↓, 1,   G6PD↑, 1,   glucose↓, 1,   glucose↑, 1,   glucose↝, 2,   GlucoseCon↑, 5,   Glycolysis↓, 1,   GSK‐3β↓, 16,   GSK‐3β↑, 1,   p‑GSK‐3β↑, 3,   H2S↑, 1,   LDL↓, 5,   NADH:NAD↑, 1,   NADPH↓, 2,   NADPH↑, 2,   PDK1 / PDPK1↓, 1,   PDKs↓, 1,   SIRT1↓, 1,   SIRT1↑, 8,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 14,   ASC↓, 1,   BAX↓, 6,   BAX↑, 1,   Bax:Bcl2↓, 1,   Bcl-2↓, 3,   Bcl-2↑, 4,   Casp↓, 1,   Casp1↓, 1,   Casp3↓, 13,   Casp3↑, 1,   cl‑Casp3↓, 1,   Casp6↓, 1,   Casp9↓, 4,   Casp9↑, 1,   Cyt‑c↓, 2,   Cyt‑c↑, 1,   Cyt‑c∅, 1,   Ferroptosis↓, 5,   iNOS↓, 20,   necrosis↓, 1,   p38↓, 1,   p38↑, 1,   p‑p38↓, 2,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 4,   Akt↑, 10,   p‑Akt↑, 3,   AKT1↓, 1,   CREB↑, 3,   p‑CREB↑, 3,   ERK↓, 4,   ERK↑, 3,   p‑ERK↓, 1,   p‑ERK↑, 2,   IGF-1R↓, 1,   JAK↓, 1,   JNK↓, 3,   p‑JNK↓, 2,   MAPK↓, 9,   MAPK↑, 3,   mTOR↓, 5,   mTOR↑, 2,   p‑mTOR↓, 1,   P70S6K↓, 1,   PDGFR-BB↓, 1,   PI3K↓, 4,   PI3K↑, 7,   PKCδ?, 1,   PKCδ↑, 3,   PTEN↓, 3,   PTP1B↓, 1,   STAT3↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   cJun↓, 1,   FOXO↑, 1,   FOXO3↑, 1,   H3↑, 1,   H4↑, 1,   HDAC1↓, 1,   HDAC2↓, 1,   HDAC3↓, 1,   MEF2D↑, 1,   other?, 2,   other↓, 4,   other↑, 8,   other↝, 7,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↓, 1,   ER Stress↓, 3,   GRP78/BiP↓, 3,   GRP78/BiP↑, 1,   HSP70/HSPA5↑, 1,   HSP70/HSPA5↝, 1,   HSP90↑, 1,   HSPs↑, 2,   IRE1↓, 1,   UPR↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

autophagy↓, 1,   Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 2,   CTSZ↓, 1,   MitoP↑, 3,   p62↓, 1,   p62↑, 1,   PARK2↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 4,   DNArepair↑, 1,   P53↓, 2,   SIRT6↑, 1,   γH2AX↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

cellSen↝, 1,   E2Fs↑, 1,   Ki-67↑, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Choline↑, 1,   GH↑, 1,   Ki-67↑, 1,   neuroG↑, 8,   Wnt↑, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 3,   AP-1↓, 3,   BACH1↓, 1,   Ca+2?, 1,   Ca+2↓, 5,   Ca+2↑, 1,   Ca+2↝, 1,   Cartilage↑, 1,   MMP13↓, 1,   MMP2↓, 3,   MMP9↓, 9,   MMPs↓, 1,   N-cadherin↑, 1,   NFAT↓, 1,   Rho↓, 1,   p‑T-cadherin↓, 1,   TG2/TGase↓, 1,   TGF-β↓, 2,   TGF-β1↑, 1,   TregCell↑, 1,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↑, 1,   CD31/PECAM-1↑, 1,   eNOS↑, 1,   Hif1a↑, 1,   NO↓, 15,   NO↑, 1,   VCAM-1↓, 6,   VEGF↑, 2,  

Barriers & Transport(tgid=15) ⓘ

BBB?, 3,   BBB↓, 10,   BBB↑, 171,   BBB↝, 14,   BBB∅, 4,   CellMemb↑, 1,   CLDN1↝, 1,   CLDN4↑, 1,   CLDN5↑, 1,   CX43/GJA1↑, 1,   EPR↑, 1,   GastroP↑, 2,   GLUT1↑, 1,   GLUT3↑, 1,   GLUT4↑, 3,   memfluid↑, 1,   MMP↑, 14,   MUC19↓, 1,   MUC2↓, 1,   OCLN↑, 2,   THBD↑, 1,   TJ↑, 2,   TJ↝, 1,   TRPM7↓, 3,   TRPM7⇅, 1,   TRPV1↑, 1,   TRPV3↑, 1,   ZO-1↑, 4,   ZO-1↝, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

AIF1/Iba-1↓, 1,   CD4+↑, 1,   CD8+↑, 1,   COX1↓, 1,   COX2/PTGS2↓, 28,   HMGB1↓, 2,   ICAM-1↓, 3,   IFN-γ↓, 1,   IL1↓, 1,   IL10↓, 1,   IL10↑, 2,   IL12↓, 1,   IL17↓, 1,   IL1α↓, 1,   IL1β↓, 33,   IL2↓, 3,   IL23↓, 1,   IL33↓, 1,   IL4↓, 4,   IL6↓, 28,   IL6↑, 2,   IL8↓, 5,   Imm↑, 3,   INF-γ↓, 2,   INF-γ↑, 1,   Inflam↓, 96,   Inflam↑, 2,   IRF3↓, 1,   MCP1/CCL2↓, 4,   MIP‑1α/CCL3↓, 1,   MyD88↓, 2,   NeuroI↓, 5,   NF-kB↓, 36,   NF-kB↑, 2,   p‑NF-kB↓, 3,   NLRP3↓, 14,   p65↓, 1,   PGE2↓, 7,   RAGE↓, 1,   RANTES↓, 2,   TLR2↓, 1,   TLR4↓, 8,   TNF-α↓, 45,   TRAF6↓, 1,   TRIF↓, 1,  

Cellular Microenvironment(tgid=17) ⓘ

GFAP↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 8,   Ach↑, 10,   AChE↓, 35,   AChE↑, 1,   ADAM10↑, 2,   ADAM10↝, 1,   BChE↓, 7,   BDNF↑, 26,   BrainVol↑, 1,   CARTPT↑, 1,   ChAT↑, 7,   GABA↓, 1,   GABA↑, 3,   MAOA↓, 5,   MAOB↓, 1,   monoA↑, 1,   NGF↑, 3,   PSD95↑, 3,   SNAP25↑, 2,   TrkB↑, 4,   TrkB↝, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 1,   APOE4↓, 1,   APP↓, 8,   cl‑APP↑, 1,   Aβ↓, 76,   Aβ42↓, 3,   BACE/β-secretase↓, 16,   BACE/β-secretase↝, 1,   PSEN1/PS1↑, 1,   tau↓, 18,   p‑tau↓, 18,   β-Amyloid↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ER(estro)↓, 1,   PPARα↑, 1,   PPARγ↑, 6,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABC↓, 1,   BioAv↓, 30,   BioAv↑, 52,   BioAv⇅, 1,   BioAv↝, 20,   BioAv∅, 1,   BioEnh↑, 4,   ChemoSen↑, 1,   CompStab↑, 1,   CYP3A2↓, 1,   CYP3A4↓, 1,   DDS↑, 2,   Dose?, 1,   Dose↓, 1,   Dose↑, 3,   Dose↝, 33,   Dose∅, 1,   eff↓, 3,   eff↑, 35,   eff↝, 1,   Half-Life↓, 7,   Half-Life↑, 4,   Half-Life↝, 14,   Half-Life∅, 1,   MRP1/ABCC1↓, 1,   P-gp/ABCB1↓, 6,   P450↓, 1,   selectivity↑, 1,   Synergy↑, 17,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 5,   anemia↓, 1,   AST↓, 6,   BG↓, 1,   BloodF↑, 3,   BP↓, 8,   BP↝, 1,   BP∅, 1,   creat↓, 2,   CRP↓, 1,   Ferritin↓, 1,   Ferritin↑, 1,   HemoG↑, 1,   IL6↓, 28,   IL6↑, 2,   LDH↓, 3,   NOS2↓, 1,   RAGE↓, 1,   RBC↑, 1,   TC↓, 1,   TMAO↑, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 2,   antiAll↑, 3,   AntiCan↑, 9,   AntiDiabetic↑, 4,   AntiMyl↑, 1,   AntiTum↑, 1,   Bone Healing↑, 1,   cardioP↑, 17,   chemoP↑, 1,   cognitive↓, 1,   cognitive↑, 86,   cognitive↝, 1,   cognitive∅, 2,   diuretic↑, 1,   fatigue↓, 1,   hepatoP↓, 2,   hepatoP↑, 10,   Learn↑, 4,   memory↓, 1,   memory↑, 68,   memory∅, 1,   Mood↑, 6,   motorD↑, 15,   Mucositis↓, 1,   neuroP?, 1,   neuroP↑, 110,   NP/CIPN↓, 1,   Obesity↓, 3,   OS↑, 2,   Pain↓, 3,   radioP↑, 1,   RenoP↓, 1,   RenoP↑, 5,   Risk↓, 3,   Sleep↑, 5,   Strength↑, 5,   Stress↓, 3,   Stroke↓, 9,   toxicity↓, 17,   toxicity↑, 2,   toxicity⇅, 1,   toxicity↝, 3,   toxicity∅, 6,   Weight↓, 1,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 6,   AntiFungal↑, 4,   AntiP↑, 2,   AntiViral↑, 4,   Bacteria↓, 7,   GutMicro↑, 18,   Sepsis↓, 3,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↑, 1,   Ingr↝, 1,  
Total Targets: 449

Scientific Paper Hit Count for: BBB, Blood-Brain Barrier Permeability
14 Selenium NanoParticles
13 Alpha-Lipoic-Acid
11 borneol
10 Curcumin
10 Hydrogen Gas
7 Honokiol
6 Luteolin
6 Methylene blue
6 Mushroom Lion’s Mane, Hericium erinaceus
6 Urolithin
5 Chlorogenic acid
5 Carvacrol
5 EGCG (Epigallocatechin Gallate)
5 Pterostilbene
4 Silver-NanoParticles
4 Berberine
4 Mung Bean Sprouts
4 Ferulic acid
4 Lycopene
4 Quercetin
4 Resveratrol
3 5-Hydroxytryptophan
3 Apigenin (mainly Parsley)
3 Bacopa monnieri
3 Choline
3 Gamma-aminobutyric acid
3 Rosmarinic acid
3 Licochalcone A
3 Rutin
3 Sulforaphane (mainly Broccoli)
2 almonertinib
2 Baicalein
2 beta-carotene(VitA)
2 Caffeic acid
2 Carnosic acid
2 Cinnamon
2 Fisetin
2 Isobavachalcone
2 Isoliquiritigenin
2 Ivermectin
2 Lactoferrin/Talactoferrin
2 Matrine
2 Melatonin
2 Vitamin B3,Niacin
2 S-adenosyl-L-methionine
2 Silymarin (Milk Thistle) silibinin
2 Thymoquinone
2 Turmerones
2 Vitamin B5,Pantothenic Acid
1 1,8-Cineole
1 acetaminophen
1 Anthocyanins
1 Allicin (mainly Garlic)
1 Acetyl-l-carnitine
1 Bevacizumab (brand Avastin)
1 Aromatherapy
1 Ashwagandha(Withaferin A)
1 Astaxanthin
1 Baicalin
1 Beta-Caryophyllene
1 Betulinic acid
1 Brucea javanica
1 Boswellia (frankincense)
1 α-Bisabolol / Chamomile oil
1 Capsaicin
1 Thymol-Thymus vulgaris
1 Cynanbungeigenin C (CBC) and D (CBD)
1 chitosan
1 Chrysin
1 Propolis -bee glue
1 Coenzyme Q10
1 Crocetin
1 Galantamine
1 Cysteamine
1 Deguelin
1 Diclofenac
1 Ginkgo biloba-EGb 761
1 Eugenol
1 Evodiamine
1 Fucoidan
1 Gambogic Acid
1 Geraniol
1 Glabrescione B
1 Gold NanoParticles
1 Hydroxycinnamic-acid
1 Huperzine A/Huperzia serrata
1 Hyperoside
1 Inositol
1 isoflavones
1 isoorientin
1 isoquercitrin
1 Magnolol
1 Isovitexin
1 Vitexin
1 mebendazole
1 MCT oil
1 Magnetic Fields
1 Mangiferin
1 Moringa oleifera
1 Methylsulfonylmethane
1 L-Theanine
1 Myricetin
1 Myrrh
1 nicotinamide adenine dinucleotide
1 Nimbolide
1 Olive Oil
1 HydroxyTyrosol
1 Oleuropein
1 Protocatechuic acid
1 Propranolol
1 Rauwolfia serpentina/Indian Snakeroot
1 Metformin
1 Taurine
1 Vitamin C (Ascorbic Acid)
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1123  State#:%  Dir#:%
wNotes=0 sortOrder:rid,rpid

 

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