QoL Cancer Research Results

QoL, Quality of Life: Click to Expand ⟱
Source:
Type:
Quality of Life
Scientific Papers found: Click to Expand⟱
5281- 3BP,    A translational study “case report” on the small molecule “energy blocker” 3-bromopyruvate (3BP) as a potent anticancer agent: from bench side to bedside
- Case Report, Var, NA
Glycolysis↓, mt-OXPHOS↓, ATP↓, selectivity↑, toxicity↝, OS↑, QoL↑,
5264- 3BP,    Candidate cancer drug suspected after death of three patients at an alternative medicine clinic
- Review, Var, NA
toxicity↑, Glycolysis↓, ChemoSen↑, OS↑, QoL↑, toxicity↝,
5428- AG,    Meta-Analysis of Astragalus-Containing Traditional Chinese Medicine Combined With Chemotherapy for Colorectal Cancer: Efficacy and Safety to Tumor Response
- Review, CRC, NA
ChemoSen↑, chemoP↑, QoL↑, RenoP∅, hepatoP∅,
5431- AG,    Advances in research on the anti-tumor mechanism of Astragalus polysaccharides
- Review, Var, NA
AntiTum↑, TumCG↓, TumCI↓, Apoptosis↑, Imm↑, Bcl-2↓, BAX↑, Wnt↓, β-catenin/ZEB1↓, TumCG↓, miR-133a-3p↑, JNK↓, Fas↑, P53↑, P21↑, NOTCH1↓, NOTCH3↓, TumCP↓, TumCCA↑, GPx4↓, xCT/SLC7A11↓, AMPK↑, Beclin-1/ATG6↑, NF-kB↓, EMT↓, Vim↓, TumMeta↓, VEGF↓, EGFR↓, eff↑, eff↑, MMP↓, P-gp/ABCB1↓, MMP9↓, ChemoSen↑, SIRT1↓, SREBP1/SREBF1↓, TumAuto↑, PI3K↓, mTOR↓, Casp3↑, Casp9↑, CD133↓, CD44↓, CSCs↓, QoL↑,
5432- AG,    Astragalus polysaccharides combined with radiochemotherapy for cervical cancer: a systematic review and meta-analysis of randomized controlled studies
- Review, Cerv, NA
ChemoSen↑, eff↑, RadioS↑, CEA↓, Wnt↓, β-catenin/ZEB1↓, γH2AX↑, ER Stress↑, mt-TumAuto↑, QoL↑, Imm↑,
5434- AG,    Recent Advances in the Mechanisms and Applications of Astragalus Polysaccharides in Liver Cancer Treatment: An Overview
- Review, Liver, NA
AntiCan↑, Apoptosis↑, TumCP↓, EMT↓, Imm↑, ChemoSen↑, BioAv↓, TumCG↓, IL2↑, IL12↑, TNF-α↑, P-gp/ABCB1↓, MDR1↓, QoL↑, Casp↑, DNAdam↑, Bcl-2↓, BAX↑, MMP↓, Cyt‑c↑, NOTCH1↓, GSK‐3β↓, TumCCA↑, GSH↓, ROS↑, lipid-P↑, c-Iron↑, GPx4↓, ACSL4↑, Ferroptosis↑, Wnt↓, β-catenin/ZEB1↓, cycD1/CCND1↓, Akt↓, PI3K↓, mTOR↓, CXCR4↓, Vim↓, PD-L1↓, eff↑, eff↑, ChemoSen↑, ChemoSen↑, chemoP↑,
5435- AG,    Efficacy of Astragalus Membranaceus (Huang Qi) for Cancer-Related Fatigue: A Systematic Review and Meta-Analysis of Randomized Controlled Studies
- Review, Var, NA
fatigue↓, QoL↑, Dose↝,
5324- ALC,    The anti-wasting effects of L-carnitine supplementation on cancer: experimental data and clinical studies
- Review, Var, NA
*cachexia↓, *Apoptosis↓, *Inflam↓, QoL↑, Dose↝, Weight↑, OS↝, fatigue↓, eff↝,
5325- ALC,    L-Carnitine-supplementation in advanced pancreatic cancer (CARPAN) - a randomized multicentre trial
- Trial, PC, NA
Weight↑, QoL↑, OS↑,
5319- ALC,    l-carnitine and cancer cachexia: Clinical and experimental aspects
- Review, Var, NA
fatigue↓, QoL↑, *GSH↑, Dose↝,
3820- Aroma,    Effectiveness and Safety of Aromatherapy in Managing Behavioral and Psychological Symptoms of Dementia: A Mixed-Methods Systematic Review
- Review, AD, NA
*QoL↑, *Mood↑,
8806- Ash,    Systematic review and network meta-analysis of the effects of plant active substance on quality of life in breast cancer patients
- Review, BC, NA
Dose?, QoL↑, fatigue↓, Pain↓, Nausea↓, chemoP↑,
5571- B-Gluc,  immuno,    Potential benefit of β-glucans as adjuvant therapy in immuno-oncology: a review
- Review, Var, NA
Imm↑, ChemoSen↑, LDL↑, GutMicro↑, TumCP↓, Apoptosis↑, angioG↓, QoL↑,
5578- B-Gluc,    A multi-institutional prospective study of lentinan in advanced gastric cancer patients with unresectable and recurrent diseases: effect on prolongation of survival and improvement of quality of life. Kanagawa Lentinan Research Group
- Trial, GC, NA
OS↑, QoL↑,
5596- BEV,    Bevacizumab may improve quality of life, but not overall survival in glioblastoma: an epidemiological study
- Study, GBM, NA
QoL↑, OS∅,
5716- BF,    Pilot Study of Huachansu in Patients with Hepatocellular Carcinoma, Non-Small Cell Lung Cancer, or Pancreatic Cancer
- Trial, NSCLC, NA - Trial, PC, NA - Trial, HCC, NA
Dose↝, toxicity↓, other↓, QoL↑, OS?,
5686- BJ,  BRU,    A review of Brucea javanica: metabolites, pharmacology and clinical application
- Review, Var, NA
AntiTum↑, other↝, ChemoSen↑, QoL↑, chemoP↑, *Inflam↓, NF-kB↓, TumCP↓, TumCI↓, TumMeta↓, Hif1a↓, NRF2↓, STAT3↓, COX2/PTGS2↓, Casp3↑, Casp9↑, ROS↑, EGFR↓, NRF2↑,
5692- BJ,    Seed oil of Brucea javanica induces apoptosis through the PI3K/Akt signaling pathway in acute lymphocytic leukemia Jurkat cells
- vitro+vivo, AML, NA
Apoptosis↑, Akt↓, P53↑, FOXO1↑, GSK‐3β↑, TumVol↓, QoL↑, BBB↑, OS↑, Dose↝, MMP↓, ROS↑, XIAP↑, Casp9↑, Casp8↑, Casp3↑, cl‑PARP↑, TumCCA↑,
5918- Cats,    Uncaria tomentosa (cat's claw) improves quality of life in patients with advanced solid tumors
- Trial, Var, NA
Dose↝, QoL↑, fatigue↓,
9141- CC,    Camu Camu (Myrciaria dubia (Kunth) McVaugh): An Amazonian Fruit with Biofunctional Properties–A Review
- Review, Nor, NA
*Ingr↝, *antiOx↑, *hyperG↓, *Obesity↓, *QoL↓, *AntiBio↑, *Inflam↓, *TumCP↓, *hepatoP↑, *Ingr↝, *eff↝, *antiAll↑, *AntiTum↑, *NRF2↑, *NQO1↑, *NA↑,
5970- CET,    Cetuximab
- Review, CRC, NA - Review, HNSCC, NA
EGFR↓, OS↑, QoL↑, Dose↝,
5968- CET,    Cetuximab as a Key Partner in Personalized Targeted Therapy for Metastatic Colorectal Cancer
- in-vitro, CRC, NA
eff↑, Half-Life↑, Half-Life↑, EGFR↓, OS↑, QoL↑, eff↑, KRAS↓,
6120- Chol,    Citicoline: A Cholinergic Precursor with a Pivotal Role in Dementia and Alzheimer’s Disease
- Trial, AD, NA
*Dose↝, *cognitive↑, *QoL?,
7433- Chy,    Evaluation of Cyavanaprāśa on Health and Immunity related Parameters in Healthy Children: A Two Arm, Randomized, Open Labeled, Prospective, Multicenter, Clinical Study
- Trial, Nor, NA
*Dose↝, *QoL↑, *Imm↑,
7435- Chy,    Golden Ager Chyawanprash with Meager Evidential Base from Human Clinical Trials
- Review, Nor, NA
*Dose↝, *antiOx↑, *Inflam↓, *Imm↑, *QoL↑, *Dose↑, *Dose↝,
3994- CoQ10,  Se,    Coenzyme Q10 Supplementation in Aging and Disease
- Review, AD, NA - Review, Park, NA
*AntiAge↑, *cardioP↑, *Inflam↓, *antiOx↑, *lipid-P↓, *QoL↑, *neuroP↑, *Dose↝, *BP↓, *IGF-1↑, *IGFBP1↑, *Synergy↑, *LDL↓, *HDL↑, *Synergy↑, *other↑, *RenoP↑, *ROS↓, *TNF-α↓, *IL6↓, *other↝, *other∅,
1809- CUR,  Oxy,    Long-term stabilisation of myeloma with curcumin
- Case Report, Melanoma, NA
*OS↑, QoL↑, Dose↑, Dose↑, IL6↓, STAT3↓, NF-kB↓, COX2/PTGS2↓,
6233- CUSP9,    A conceptually new treatment approach for relapsed glioblastoma: Coordinated undermining of survival paths with nine repurposed drugs CUSP9 by the International Initiative for Accelerated Improvement of Glioblastoma Care
- Review, GBM, NA
other↝, QoL↑,
1910- CUSP9,    A conceptually new treatment approach for relapsed glioblastoma: coordinated undermining of survival paths with nine repurposed drugs (CUSP9) by the International Initiative for Accelerated Improvement of Glioblastoma Care
- Analysis, GBM, NA
Dose↝, QoL↑, Dose↝,
9108- CV,    The influence of chlorella and its hot water extract supplementation on quality of life in patients with breast cancer
- Trial, BC, NA
Dose↝, fatigue↓, QoL↑, Ingr↝, Dose↝, Perforin↑,
1880- DCA,    A Novel Form of Dichloroacetate Therapy for Patients With Advanced Cancer: A Report of 3 Cases
- Case Report, Var, NA
OS↑, angioG↓, Hif1a↝, pH↝, QoL↑,
1879- DCA,    Long-term stabilization of metastatic melanoma with sodium dichloroacetate
- Case Report, Melanoma, NA
OS↑, toxicity↓, Dose∅, Dose∅, Dose∅, QoL∅,
6751- DHA,    Exploratory outcomes of the DHA WIN randomized controlled trial: Supplementing women with docosahexaenoic acid did not reduce the impact of neoadjuvant breast cancer chemotherapy on quality of life or exercise behaviour
- Trial, BC, NA
QoL∅,
1849- dietFMD,    The emerging role of fasting-mimicking diets in cancer treatment
- Review, Var, NA
TumCG↓, toxicity∅, BG↓, IGF-1↓, mTOR↓, M2 MC↓, eff↑, ChemoSen↑, QoL↑, RadioS↑, selectivity↑,
1853- dietFMD,    Impact of Fasting on Patients With Cancer: An Integrative Review
- Review, Var, NA
*toxicity∅, QoL∅, eff↑, eff↝, ChemoSideEff↓, TumCG↓, Dose↑, toxicity↝, eff↑, IGF-1↑, *OXPHOS↑, BG↓, Insulin↓, RadioS↑,
1855- dietFMD,    Impact of modified short-term fasting and its combination with a fasting supportive diet during chemotherapy on the incidence and severity of chemotherapy-induced toxicities in cancer patients - a controlled cross-over pilot study
- Trial, Var, NA
ChemoSideEff↓, QoL↑, IGF-1↓, Insulin↓,
5069- dietSTF,    The Role of Intermittent Fasting in the Activation of Autophagy Processes in the Context of Cancer Diseases
- Review, Var, NA
Risk↓, ChemoSen↑, RadioS↑, *Dose↝, *Dose↝, *Dose↝, *LDL↓, *CRP↓, *TNF-α↓, TumAuto↓, GLUT1↓, GLUT2↓, glucose↓, IGF-1↓, Insulin↓, mTOR↓, mTORC1↓, AMPK↑, Warburg↓, OXPHOS↑, ROS↑, DNAdam↑, JAK1↓, STAT↓, TumCP↓, QoL↑,
5071- dietSTF,    Unraveling the impact of intermittent fasting in cancer prevention, mitigation, and treatment: A narrative review
- Review, Var, NA - Review, AD, NA
Risk↓, TumCMig↓, IGF-1↓, TumAuto↑, Inflam↓, ChemoSen↑, Apoptosis↑, chemoP↑, *glucose↓, *AntiDiabetic↑, *cardioP↑, *LDL↓, *BP↓, *neuroP↑, *cognitive↑, *memory↑, *OS↑, *QoL↑, Imm↑, TumCG↓, ChemoSideEff↓, QoL↑,
8833- DIM,    A phase I dose-escalation study of oral BR-DIM (BioResponse 3,3'- Diindolylmethane) in castrate-resistant, non-metastatic prostate cancer
- Trial, Pca, NA
AR↓, PSA↓, Dose↝, BioAv↝, toxicity↓, toxicity↝, Dose↝, QoL↝,
6346- DRE,    Unusual Response of Acute Monocytic Leukemia to Dandelion Root Extract
- Case Report, AML, NA
QoL↑, other↑, Dose↝,
6364- DRE,    Dandelion Root Extract Sensitizes Leukemia Cells to VP-16 Induced Cell Death
- in-vitro, CLL, NA
TumCP↓, MMP↓, ROS↑, TumCD↑, ChemoSen↑, chemoP↑, QoL↑,
4253- EA,    The effects of Ellagic acid supplementation on neurotrophic, inflammation, and oxidative stress factors, and indoleamine 2, 3-dioxygenase gene expression in multiple sclerosis patients with mild to moderate depressive symptoms: A randomized, triple-blind, placebo-controlled trial
- Human, MS, NA - NA, IBD, NA
*Mood↑, *BDNF↑, *5HT↑, *antiOx↑, *Inflam↓, *AntiCan↑, *QoL↑, *neuroP↑, *cognitive↑, *memory↑, *Dose↝,
6803- EA,    Effects of Ellagic Acid on Oxidative Stress Index, Inflammatory Markers and Quality of Life in Patients With Irritable Bowel Syndrome: Randomized Double-blind Clinical Trial
- Trial, IBD, NA
*Dose↝, *MDA↓, *TAC↑, *CRP↓, *IL6↓, *Inflam↓, *ROS↓, *QoL↑, *toxicity↓,
7203- EGb 761,    Ginkgo biloba extract EGb 761 is safe and effective in the treatment of mild dementia - a meta-analysis of patient subgroups in randomised controlled trials
- Review, AD, NA
cognitive↑, QoL↑, Dose↝,
6791- EPA,    An eicosapentaenoic acid supplement versus megestrol acetate versus both for patients with cancer-associated wasting: a North Central Cancer Treatment Group and National Cancer Institute of Canada collaborative effort
- vitro+vivo, Var, NA
Dose↝, Weight↑, eff↑, OS∅, QoL∅,
6792- EPA,    Effect of Eicosapentaenoic Acid on Body Composition and Inflammation Markers in Patients with Head and Neck Squamous Cell Cancer from a Public Hospital in Mexico
- Trial, HNSCC, NA
Dose↝, *IL1β↓, *IL6↓, *TNF-α↓, *IFN-γ↓, QoL↑,
4137- Ex,    The impact of exercise on patients with dementia
- Trial, AD, NA
*Strength↑, *QoL↑, *cognitive∅,
5055- Ex,    Why exercise has a crucial role in cancer prevention, risk reduction and improved outcomes
- Review, Var, NA
OS↑, IGF-1↓, IGFBP3↑, BRCA1↑, BRCA2↑, RAS↓, P53↑, HSPs↑, Leptin↓, Irisin↓, Resistin↓, NK cell↑, CRP↓, IL6↓, TNF-α↓, PGE1↓, COX2/PTGS2↓, *GSH↑, *Catalase↑, *SOD↑, *monoA↑, *EndoR↑, *testos↑, ROS↑, QoL↑, BMD↑, BowelM↑,
4075- FA,    Folic acid, ageing, depression, and dementia
- Review, AD, NA
*Mood↑, *cognitive↑, *other↝, *memory↑, *QoL↑, *Hcy/homoC↝, *other↝, *Dose↝,
8307- FS,  lign,    Efficacy and safety of a flaxseed hull extract in the symptomatic management of benign prostatic hyperplasia: a parallel, randomized, double-blind, placebo-controlled, pilot study
- Trial, BPH, NA
*Dose↝, *IPSS↓, *toxicity↓, *QoL↑, *other↝,

Showing Research Papers: 1 to 50 of 113
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 113

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 2,   Catalase↑, 2,   GPx↑, 3,   GPx4↓, 2,   GSH↓, 2,   GSH↑, 1,   HO-1↑, 1,   c-Iron↑, 1,   lipid-P↑, 1,   MDA↓, 1,   NRF2↓, 1,   NRF2↑, 2,   ROS↓, 1,   ROS↑, 18,   SOD↑, 2,   xCT/SLC7A11↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh∅, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ETC↓, 1,   Insulin↓, 4,   mtDam↓, 1,   OXPHOS↑, 1,   mt-OXPHOS↓, 1,   PGC-1α↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACSL4↑, 1,   AMPK↑, 2,   ATP↓, 1,   glucose↓, 1,   glucose↝, 1,   Glycolysis↓, 2,   GSK‐3β↓, 1,   GSK‐3β↑, 1,   LDL↓, 1,   LDL↑, 1,   lipoGen↓, 1,   PDK1 / PDPK1↓, 1,   SCD1↓, 1,   SIRT1↓, 1,   SREBP1/SREBF1↓, 1,   Warburg↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 11,   BAX↑, 3,   Bcl-2↓, 3,   Casp↑, 1,   Casp3↑, 8,   Casp8↑, 1,   Casp9↑, 4,   Cyt‑c↑, 2,   Cyt‑c↝, 1,   Fas↑, 1,   Ferroptosis↑, 1,   IAP2/BIRC3↓, 1,   Perforin↑, 1,   survivin↓, 1,   TumCD↑, 2,   XIAP↓, 2,   XIAP↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 8,   p‑Akt↓, 1,   BRAF↓, 1,   DYRK1B↓, 1,   EGFR↓, 4,   ERK↓, 2,   JAK1↓, 1,   JNK↓, 1,   MAPK↓, 1,   MEK↓, 1,   mTOR↓, 5,   PI3K↓, 7,   p‑PI3K↓, 1,   RAS↓, 1,   STAT↓, 1,   STAT3↓, 3,  

Transcription & Epigenetics(tgid=7) ⓘ

ChrMod↑, 1,   DNMT3B↓, 1,   EZH2↓, 1,   FOXO1↑, 1,   FOXO3↓, 1,   miR-124-3p↓, 1,   miR-133a-3p↑, 1,   other?, 1,   other↓, 1,   other↑, 2,   other↝, 6,   SD↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↑, 1,   HSP70/HSPA5↑, 1,   HSPs↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↑, 1,   TumAuto↓, 1,   TumAuto↑, 2,   mt-TumAuto↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

BRCA1↑, 1,   BRCA2↑, 1,   DNAdam↑, 3,   DNArepair↓, 1,   P53↑, 4,   cl‑PARP↑, 2,   PCNA↓, 1,   γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 1,   CDK4↓, 2,   CDK6↑, 1,   cycD1/CCND1↓, 1,   mitA↑, 1,   P21↓, 1,   P21↑, 3,   p27/CDKN1B↓, 1,   p27/CDKN1B↑, 1,   p‑pRB↓, 2,   TubPol↓, 1,   TumCCA↑, 13,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CD133↓, 1,   CSCs?, 1,   CSCs↓, 2,   Diff↑, 3,   Gli1↓, 1,   HH↓, 1,   IGF-1↓, 6,   IGF-1↑, 1,   IGFBP3↑, 1,   mTORC1↓, 1,   NOTCH1↓, 3,   NOTCH3↓, 1,   OGFr↑, 1,   PTCH2↓, 1,   Shh↓, 1,   TumCG↓, 11,   TumCP↓, 11,   Wnt↓, 5,  

Migration(tgid=13) ⓘ

Ca+2↑, 3,   Cofilin↓, 1,   E-cadherin↑, 1,   EMT↓, 3,   fascin↓, 1,   KRAS↓, 1,   MALAT1↓, 1,   MMP7↓, 1,   MMP9↓, 2,   MMPs↓, 2,   N-cadherin↓, 1,   ROCK1↓, 1,   Snail↓, 1,   TumCI↓, 4,   TumCMig↓, 2,   TumMeta?, 1,   TumMeta↓, 8,   Vim↓, 2,   β-catenin/ZEB1↓, 5,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 9,   Hif1a↓, 3,   Hif1a↝, 1,   Hypoxia↓, 1,   VCAM-1↓, 1,   VEGF↓, 4,   VEGFR2/KDR/Flk1↓, 1,   VEGFR2/KDR/Flk1↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 2,   EPR↑, 1,   GastroP↑, 1,   GLUT1↓, 1,   GLUT2↓, 1,   MMP↓, 6,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

ANXA1↓, 1,   CD4+↑, 1,   CD44↓, 1,   CD47↓, 1,   CD8+↑, 3,   COX2/PTGS2↓, 5,   CR3↝, 1,   CXCR4↓, 1,   DCells↑, 2,   Eos↑, 1,   IL10↑, 1,   IL12↑, 1,   IL1β↓, 1,   IL2↑, 1,   IL4↑, 1,   IL6↓, 5,   Imm↑, 12,   Inflam↓, 3,   Inflam↑, 1,   M2 MC↓, 1,   NF-kB↓, 6,   NK cell↑, 6,   NLRP3↑, 1,   PD-L1↓, 1,   PGE1↓, 1,   PGE2↓, 2,   PSA↓, 2,   PSA∅, 1,   Resistin↓, 1,   T-Cell↑, 2,   TNF-α↓, 4,   TNF-α↑, 1,  

Cellular Microenvironment(tgid=17) ⓘ

pH↝, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

SYN1↑, 1,  

Protein Aggregation(tgid=19) ⓘ

PSEN1/PS1↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 1,   GR↑, 1,   Irisin↓, 1,   Leptin↓, 1,   PPARγ↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 2,   BioAv↑, 3,   BioAv↝, 1,   chemoR↓, 1,   ChemoSen?, 1,   ChemoSen↑, 33,   Dose?, 2,   Dose↑, 5,   Dose⇅, 1,   Dose↝, 40,   Dose∅, 5,   eff↑, 16,   eff↝, 2,   eff∅, 2,   Half-Life↑, 2,   Half-Life↝, 1,   MDR1↓, 2,   P-gp/ABCB1↓, 3,   RadioS?, 1,   RadioS↑, 5,   selectivity↑, 9,   Synergy↑, 10,   Synergy∅, 1,   TET2↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALB∅, 1,   AR↓, 1,   BG↓, 2,   BloodF↑, 1,   BMD↑, 1,   BRAF↓, 1,   BRCA1↑, 1,   CA125↓, 1,   CEA↓, 1,   CRP↓, 1,   CRP∅, 1,   EGFR↓, 4,   EZH2↓, 1,   HemoG↑, 1,   IL6↓, 5,   KRAS↓, 1,   PD-L1↓, 1,   PSA↓, 2,   PSA∅, 1,   RBC↑, 2,   WBC↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AEs∅, 1,   AntiCan↑, 5,   antiD↑, 2,   AntiTum↑, 4,   ANXi↓, 1,   Appetite↑, 2,   BowelM↑, 2,   breath↑, 1,   chemoP↑, 23,   chemoPv↑, 2,   ChemoSideEff↓, 4,   cognitive↑, 2,   CR↑, 1,   DCR↑, 3,   fatigue↓, 6,   fatigue∅, 1,   hepatoP↑, 2,   hepatoP∅, 1,   kidSt↓, 1,   LC↑, 1,   mal↓, 1,   Mood↑, 1,   Nausea↓, 2,   neuroP↑, 1,   NP/CIPN↓, 1,   ORR∅, 1,   OS?, 1,   OS↑, 24,   OS⇅, 1,   OS↝, 1,   OS∅, 4,   Pain↓, 6,   PFS↑, 2,   PFS∅, 1,   QoL↑, 74,   QoL↝, 1,   QoL∅, 9,   radioP↑, 8,   Remission↑, 1,   RenoP↑, 1,   RenoP∅, 1,   Risk↓, 6,   Sleep↑, 2,   Strength↑, 3,   toxicity↓, 10,   toxicity↑, 1,   toxicity↝, 6,   toxicity∅, 1,   TumVol↓, 8,   TumVol↑, 1,   TumW↓, 2,   Vomit↓, 1,   Weight↑, 6,   Weight∅, 1,  

Infection & Microbiome(tgid=24) ⓘ

GutMicro↑, 2,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 1,  
Total Targets: 303

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 1,   NA↝, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 10,   Catalase↑, 6,   Fenton↓, 1,   GPx↑, 2,   GPx3↑, 1,   GSH↑, 2,   GSR↑, 1,   HDL↑, 1,   HO-1↑, 4,   hyperG↓, 1,   Iron∅, 1,   lipid-P↓, 3,   MDA↓, 4,   MPO↓, 2,   NOX↓, 1,   NOX4↓, 1,   NQO1↑, 1,   NRF2↑, 5,   RNS↓, 1,   ROS↓, 8,   selenoP↑, 2,   SOD↑, 5,   SOD2↑, 1,   TAC↑, 3,   TBARS↓, 1,   VitE↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compII↑, 1,   compIII↑, 1,   Insulin↓, 1,   OXPHOS↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,   AMPK↑, 1,   ATP↑, 1,   glucose↓, 2,   LDL↓, 4,   NADPH↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 2,   Bcl-2↑, 1,   Bcl-xL↑, 1,   Casp12↓, 1,   Casp3↓, 1,   Casp9↓, 1,   Fas↓, 1,   FasL↓, 1,   GranB/GZMB↓, 1,   p38↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↑, 2,   JAK2↑, 1,   p‑JNK↓, 1,   mTOR↓, 2,   PI3K↑, 2,   STAT3↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   ATF4↓, 1,   other?, 1,   other↑, 4,   other↝, 4,   other∅, 1,   tumCV↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   p‑eIF2α↓, 1,   ER Stress↓, 1,   GRP78/BiP↓, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

LC3‑Ⅱ/LC3‑Ⅰ↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 2,   P53↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

P21↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

IGF-1↑, 1,   IGFBP1↑, 1,   TumCP↓, 2,  

Migration(tgid=13) ⓘ

Ca+2↑, 1,   Cartilage↑, 2,   MMP9↓, 1,   TGF-β↑, 2,   TumCI↓, 1,   TumCMig↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

NO↑, 1,   VEGF↑, 1,  

Barriers & Transport(tgid=15) ⓘ

IBI↑, 1,   MMP↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD25+↑, 1,   CD4+↑, 2,   COX2/PTGS2↓, 1,   FOXP3↑, 1,   GM-CSF↑, 1,   HMGB1↓, 1,   IFN-γ↓, 2,   IL10↑, 2,   IL1β↓, 3,   IL4↓, 2,   IL4↑, 1,   IL6↓, 6,   Imm↑, 3,   Inflam↓, 15,   IP-10/CXCL-10↑, 1,   LPS↓, 1,   M2 MC↑, 1,   MCP1/CCL2↓, 1,   NF-kB↓, 2,   NLRP3↓, 2,   PGE2↓, 1,   PGE2↑, 1,   TNF-α↓, 7,   Treg lymp↝, 1,   TREM-1↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   5HT↑, 1,   BDNF↑, 2,   EndoR↑, 1,   monoA↑, 1,   β-Endo↑, 1,  

Protein Aggregation(tgid=19) ⓘ

APP↓, 1,   Aβ↓, 1,   BACE/β-secretase↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

testos↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↝, 1,   Dose?, 1,   Dose↓, 1,   Dose↑, 2,   Dose↝, 26,   eff↑, 3,   eff↝, 1,   Synergy↑, 3,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   AST↓, 1,   BG↓, 1,   BloodF↑, 1,   BMD↑, 3,   BP↓, 2,   creat↓, 1,   CRP↓, 2,   Hcy/homoC↝, 1,   IL6↓, 6,   PV↓, 1,   SpO2↑, 1,   TC↓, 1,   TG/TAG↓, 1,   UFR↑, 2,   UR↓, 1,   Urea↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 2,   antiAll↑, 3,   AntiCan↑, 1,   AntiDiabetic↑, 2,   antiPs↑, 1,   AntiTum↑, 1,   cachexia↓, 1,   cardioP↑, 4,   cognitive↑, 7,   cognitive∅, 1,   hepatoP↑, 4,   IPSS↓, 1,   memory↑, 5,   Mood↑, 5,   motorD↑, 2,   neuroP↑, 6,   Obesity↓, 2,   OS↑, 4,   Pain↓, 7,   QoL?, 1,   QoL↓, 1,   QoL↑, 28,   QoL∅, 1,   radioP↑, 1,   RenoP↑, 3,   Sleep↑, 1,   Strength↑, 1,   Stress↓, 1,   Stroke↓, 1,   Tinn↓, 1,   toxicity↓, 6,   toxicity∅, 3,   Weight↓, 1,   Weight↑, 1,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 1,   AntiViral↑, 1,   GutMicro↑, 1,   Sepsis↓, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 2,  
Total Targets: 183

Scientific Paper Hit Count for: QoL, Quality of Life
8 Magnetic Fields
7 phytic acid, Inositol hexakisphosphate
6 Hydrogen Gas
5 Astragalus
5 Chemotherapy
4 Inositol
3 Acetyl-l-carnitine
3 diet FMD Fasting Mimicking Diet
3 Exercise
3 Fucoidan
3 Vitamin C (Ascorbic Acid)
3 Radiotherapy/Radiation
3 Melatonin
3 Mistletoe/Viscum album Extracts
2 3-bromopyruvate
2 beta-glucans
2 Brucea javanica
2 cetuximab
2 Chyawanprash
2 Selenium
2 CUSP9
2 Dichloroacetate
2 diet Short Term Fasting
2 Dandelion Root
2 Ellagic acid
2 eicosapentaenoic acid
2 Folic Acid, Vit B9
2 Lutein
2 MCT, metronomic chemo
2 Magnetic Field Rotating
2 Psilocybin
2 Selenite (Sodium)
1 Aromatherapy
1 Ashwagandha(Withaferin A)
1 immunotherapy
1 Bevacizumab (brand Avastin)
1 Bufalin/Huachansu
1 brusatol
1 Cat’s Claw
1 Camu camu
1 Choline
1 Coenzyme Q10
1 Curcumin
1 Oxygen, Hyperbaric
1 Chlorella (Chlorella vulgaris)
1 Docosahexaenoic Acid
1 Diindolylmethane
1 Ginkgo biloba-EGb 761
1 Flaxseed/Linseed
1 SDG/lignans
1 Flaxseed Oil
1 Vitamin D3
1 Ginger/6-Shogaol/Gingerol
1 High-Ozonide Oil
1 Hyperthermia
1 itraconazole
1 low dose naltrexone
1 Zeaxanthin
1 Lycopene
1 Matrine
1 Cisplatin
1 mebendazole
1 Modified Citrus Pectin
1 Lemon Balm/Melissa officinalis
1 Methylsulfonylmethane
1 Helleborus niger extracts – Christmas Rose
1 Mushroom Reishi
1 Oleocanthal
1 Paclitaxel/Taxol
1 Aidi injection
1 Patchouli Oil (Pogostemon cablin)
1 Phenethyl isothiocyanate
1 EMF
1 Shikonin
1 Spirulina(Arthrospira/Limnospira)
1 Vitamin B12
1 Whole Body Vibration
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1141  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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