| Source: |
| Type: type of cell death |
| Situation in which a cell actively pursues a course toward death upon receiving certain stimuli. Cancer is one of the scenarios where too little apoptosis occurs, resulting in malignant cells that will not die. |
| 5861- | CAP, | Anticancer Properties of Capsaicin Against Human Cancer |
| - | Review, | Var, | NA |
| 5858- | CAP, | Capsaicin as a Microbiome Modulator: Metabolic Interactions and Implications for Host Health |
| - | Review, | Nor, | NA | - | Review, | AD, | NA |
| 5856- | CAP, | Potential of capsaicin as a combinatorial agent to overcome chemoresistance and to improve outcomes of cancer therapy |
| - | Review, | Var, | NA |
| 5849- | CAP, | The Impact of TRPV1 on Cancer Pathogenesis and Therapy: A Systematic Review |
| - | Review, | Var, | NA |
| 5848- | CAP, | SRF, | Capsaicin exerts synergistic antitumor effect with sorafenib in hepatocellular carcinoma cells through AMPK activation |
| - | in-vitro, | HCC, | HepG2 | - | in-vitro, | HCC, | HUH7 |
| 5845- | CAP, | Unveiling the Molecular Mechanisms Driving the Capsaicin-Induced Immunomodulatory Effects on PD-L1 Expression in Bladder and Renal Cancer Cell Lines |
| - | in-vivo, | RCC, | A498 | - | in-vitro, | RCC, | T24/HTB-9 | - | NA, | Bladder, | 5637 |
| 5843- | CAP, | The Effects of Capsaicin on Gastrointestinal Cancers |
| - | Review, | GC, | NA |
| 5203- | CAP, | Capsaicin Promotes Apoptosis and Inhibits Cell Migration via the Tumor Necrosis Factor-Alpha (TNFα) and Nuclear Factor Kappa B (NFκB) Signaling Pathway in Oral Cancer Cells |
| - | in-vitro, | OS, | KB |
| 5201- | CAP, | Inhibiting ROS-STAT3-dependent autophagy enhanced capsaicin-induced apoptosis in human hepatocellular carcinoma cells |
| - | in-vitro, | HCC, | HepG2 |
| 5198- | CAP, | Capsaicin induces apoptosis by generating reactive oxygen species and disrupting mitochondrial transmembrane potential in human colon cancer cell lines |
| - | in-vitro, | CRC, | LoVo | - | in-vitro, | CRC, | Colo320 |
| 5199- | CAP, | Capsaicin is a novel blocker of constitutive and interleukin-6-inducible STAT3 activation |
| - | vitro+vivo, | AML, | NA |
| 1262- | CAP, | Capsaicin Inhibits Proliferation and Induces Apoptosis in Breast Cancer by Down-Regulating FBI-1-Mediated NF-κB Pathway |
| - | vitro+vivo, | BC, | NA |
| 2012- | CAP, | Capsaicin induces cytotoxicity in human osteosarcoma MG63 cells through TRPV1-dependent and -independent pathways |
| - | in-vitro, | OS, | MG63 |
| 2014- | CAP, | Role of Mitochondrial Electron Transport Chain Complexes in Capsaicin Mediated Oxidative Stress Leading to Apoptosis in Pancreatic Cancer Cells |
| - | in-vitro, | PC, | Bxpc-3 | - | in-vitro, | Nor, | HPDE-6 | - | in-vivo, | PC, | AsPC-1 |
| 2019- | CAP, | Capsaicin: A Two-Decade Systematic Review of Global Research Output and Recent Advances Against Human Cancer |
| - | Review, | Var, | NA |
| 8695- | CAP, | Advances in cold atmospheric plasma therapy for cancer |
| - | Review, | Var, | NA |
| 8702- | CAP, | Current Status and Future Trends of Cold Atmospheric Plasma as an Oncotherapy |
| - | Review, | Var, | NA |
| 8701- | CAP, | Comparative assessment of direct and indirect cold atmospheric plasma effects, based on helium and argon, on human glioblastoma: an in vitro and in vivo study |
| - | vitro+vivo, | GBM, | GBM | - | in-vitro, | GBM, | U87MG |
| 2652- | CAP, | Oxidative Stress Inducers in Cancer Therapy: Preclinical and Clinical Evidence |
| - | Review, | Var, | NA |
| 5764- | CAPE, | Caffeic Acid Phenethyl Ester (CAPE), Derived from a Honeybee Product Propolis, Exhibits a Diversity of Anti-tumor Effects in Preclinical Models of Human Breast Cancer |
| - | vitro+vivo, | BC, | MCF7 | - | NA, | BC, | MDA-MB-231 |
| 5762- | CAPE, | Caffeic acid phenethyl ester promotes oxaliplatin sensitization in colon cancer by inhibiting autophagy |
| - | in-vitro, | CRC, | SW480 | - | in-vitro, | CRC, | HCT116 |
| 7520- | CAPE, | Neuroprotective Effect of Caffeic Acid Phenethyl Ester in A Mouse Model of Alzheimer's Disease Involves Nrf2/HO-1 Pathway |
| - | in-vivo, | AD, | NA |
| 5887- | CAR, | TV, | Antitumor Effects of Carvacrol and Thymol: A Systematic Review |
| - | Review, | Var, | NA |
| 5885- | CAR, | Inhibition of TRPM7 by carvacrol suppresses glioblastoma cell proliferation, migration and invasion |
| - | in-vitro, | GBM, | U87MG | - | in-vitro, | Nor, | HEK293 |
| 5882- | CAR, | Carvacrol Promotes Cell Cycle Arrest and Apoptosis through PI3K/AKT Signaling Pathway in MCF-7 Breast Cancer Cells |
| - | in-vitro, | BC, | MCF7 |
| 5880- | CAR, | In vitro and in vivo antitumor potential of carvacrol nanoemulsion against human lung adenocarcinoma A549 cells via mitochondrial mediated apoptosis |
| - | vitro+vivo, | Lung, | A549 | - | in-vitro, | Nor, | BEAS-2B | - | in-vitro, | Lung, | PC9 |
| 5888- | CAR, | Therapeutic application of carvacrol: A comprehensive review |
| - | Review, | Var, | NA | - | Review, | Stroke, | NA | - | Review, | Diabetic, | NA | - | Review, | Park, | NA |
| 5907- | CAR, | Anti-proliferative and pro-apoptotic effect of carvacrol on human hepatocellular carcinoma cell line HepG-2 |
| - | in-vitro, | Liver, | HepG2 |
| 5910- | CAR, | Oregano Phytocomplex Induces Programmed Cell Death in Melanoma Lines via Mitochondria and DNA Damage |
| - | in-vitro, | Melanoma, | B16-F10 | - | NA, | NA, | A375 |
| 5903- | CAR, | TV, | Combined Cytotoxic Effects of Carvacrol-Based Essential Oil Formulations |
| - | in-vitro, | BC, | MDA-MB-231 |
| 5902- | CAR, | A novel antagonist of TRPM2 and TRPV4 channels: Carvacrol |
| - | in-vitro, | Nor, | HEK293 |
| 5901- | CAR, | Neuroprotective role of carvacrol in ischemic brain injury: a systematic review of preclinical evidence and proposed TRPM7 involvement |
| - | Review, | Stroke, | NA |
| 5897- | CAR, | Carvacrol Selectively Induces Mitochondria-Related Apoptotic Signaling in Primary Breast Cancer-Associated Fibroblasts |
| - | in-vitro, | BC, | NA |
| 5895- | CAR, | Carvacrol as a Therapeutic Candidate in Breast Cancer: Insights into Subtype-Specific Cellular Modulation |
| - | in-vitro, | BC, | MCF7 | - | in-vitro, | BC, | MDA-MB-231 |
| 5894- | CAR, | Targeting Gastrointestinal Cancers with Carvacrol: Mechanistic Insights and Therapeutic Potential |
| - | Review, | Var, | NA |
| 5893- | CAR, | TV, | Thymol and Carvacrol: Molecular Mechanisms, Therapeutic Potential, and Synergy With Conventional Therapies in Cancer Management |
| - | Review, | Var, | NA |
| 1287- | CAR, | Carvacrol induces apoptosis in human breast cancer cells via Bcl-2/CytC signaling pathway |
| - | in-vitro, | BC, | HCC1937 |
| 5920- | Cats, | Treatment with Uncaria tomentosa Promotes Apoptosis in B16-BL6 Mouse Melanoma Cells and Inhibits the Growth of B16-BL6 Tumours |
| - | in-vivo, | Melanoma, | B16-BL6 |
| 5919- | Cats, | Cisplatin, | Uncaria tomentosa Leaves Decoction Modulates Differently ROS Production in Cancer and Normal Cells, and Effects Cisplatin Cytotoxicity |
| - | in-vitro, | Liver, | HepG2 |
| 5915- | Cats, | Oxindole alkaloids from Uncaria tomentosa induce apoptosis in proliferating, G0/G1-arrested and bcl-2-expressing acute lymphoblastic leukaemia cells |
| - | in-vitro, | AML, | NA |
| 1103- | CBD, | Cannabidiol inhibits invasion and metastasis in colorectal cancer cells by reversing epithelial-mesenchymal transition through the Wnt/β-catenin signaling pathway |
| - | vitro+vivo, | CRC, | NA |
| 5817- | CBD, | COX-2 and PPAR-γ confer cannabidiol-induced apoptosis of human lung cancer cells |
| - | vitro+vivo, | Lung, | A549 |
| 5819- | CBD, | The potential role of cannabidiol (CBD) in lung cancer therapy: a systematic review of preclinical and clinical evidence |
| - | Review, | Lung, | NA |
| 5965- | CEL, | Cisplatin, | Celecoxib enhances anticancer effect of cisplatin and induces anoikis in osteosarcoma via PI3K/Akt pathway |
| - | in-vitro, | OS, | MG63 |
| 5964- | CEL, | Celecoxib pathways: pharmacokinetics and pharmacodynamics |
| - | Review, | Var, | NA |
| 5959- | CEL, | Celecoxib induces apoptosis in cervical cancer cells independent of cyclooxygenase using NF-κB as a possible target |
| - | in-vitro, | Cerv, | HeLa |
| 5957- | CEL, | Celecoxib induces apoptosis by inhibiting 3-phosphoinositide-dependent protein kinase-1 activity in the human colon cancer HT-29 cell line |
| - | in-vitro, | Colon, | HT29 |
| 5956- | CEL, | Direct non-cyclooxygenase-2 targets of celecoxib and their potential relevance for cancer therapy |
| - | Review, | Var, | NA |
| 5954- | CEL, | The molecular mechanisms of celecoxib in tumor development |
| - | Review, | Var, | NA |
| 5939- | Cela, | Chemo, | Celastrol inhibits proliferation and induces chemosensitization through down-regulation of NF-κB and STAT3 regulated gene products in multiple myeloma cells |
| - | in-vitro, | Melanoma, | U266 | - | in-vitro, | Melanoma, | RPMI-8226 |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:14 State#:% Dir#:%
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