TumCP Cancer Research Results

TumCP, Tumor Cell proliferation: Click to Expand ⟱
Source:
Type:
Tumor cell proliferation is a key characteristic of cancer. It refers to the rapid and uncontrolled growth of cells that can lead to the formation of tumors.
Scientific Papers found: Click to Expand⟱
1189- Gb,    New insight into the mechanisms of Ginkgo biloba leaves in the treatment of cancer
- Review, NA, NA
Apoptosis↑, TumCP↓, TumCI↓, TumCMig↓, Inflam↓, antiOx↑, angioG↓,
28- GEN,    Genistein decreases the breast cancer stem-like cell population through Hedgehog pathway
- in-vivo, BC, MCF-7
HH↓, Smo↓, Gli1↓, TumCG↓, TumCP↓, Apoptosis↑, CSCs↓,
30- Ger,    A sesquiterpene lactone from Siegesbeckia glabrescens suppresses Hedgehog/Gli-mediated transcription in pancreatic cancer cells
- in-vitro, PC, PANC1 - in-vitro, PC, AsPC-1
HH↓, Gli1↓, Shh↓, cycD1/CCND1↓, TumCP↓,
6566- Ger,  5-FU,    Geraniol, a Component of Plant Essential Oils, Sensitizes Human Colonic Cancer Cells to 5-Fluorouracil Treatment
- in-vitro, CRC, NA
TumCP↓, ChemoSen↑, other↝, EPR↑,
6564- Ger,    Effect of geraniol on fatty-acid and mevalonate metabolism in the human hepatoma cell line Hep G2
- in-vitro, HCC, HepG2
TumCG↓, HMG-CoA↓, TumCP↓, eff↑, Dose↝,
6562- Ger,    Potential Effects of Geraniol on Cancer and Inflammation-Related Diseases: A Review of the Recent Research Findings
- Review, Var, NA - Review, AD, NA
*Inflam↓, *AntiCan↑, *AntiBio↑, *antiOx↑, *neuroP↑, ROS↓, Apoptosis↑, TumCCA↑, P53↝, STAT3↓, Casp↝, *Catalase↑, *GSTs↑, *GPx↑, *AChE↓, *GSH↑, *SOD↑, *TBARS↓, *NO↓, *XO↓, *memory↑, *IL1β↓, *iNOS↓, *NF-kB↓, *COX2↓, *NRF2↑, *HO-1↑, *survivin↓, TumCP↓, TumCMig↓, TumCG↑, selectivity↑, TumMeta↓, angioG↓, Hif1a↓, Beclin-1↓,
6567- Ger,    Geraniin inhibits proliferation and induces apoptosis through inhibition of phosphatidylinositol 3-kinase/Akt pathway in human colorectal cancer in vitro and in vivo
- vitro+vivo, CRC, SW480 - in-vitro, CRC, HT29
AntiTum↑, *Inflam↓, *antiOx↓, TumCP↓, BAX↑, Casp3↑, Casp9↑, Bcl-2↓, TumCMig↓, TumCI↓, MMP2↓, MMP9↓, p‑PI3K↓, p‑Akt↓, Dose↝, TumCG↓,
6570- Ger,    Apoptosis-Mediated Anticancer Activity of Geraniol Inhibits NF-κB, MAPK, and JAK-STAT-3 Signaling Pathways in Human Thyroid Cancer Cells
- in-vitro, Thyroid, TPC-1
*Inflam↓, AntiCan↑, *neuroP↑, tumCV↓, TumCP↓, ROS↑, Apoptosis?, MMP↓, Bcl-2↓, cycD1/CCND1↓, cMyc↓, COX2↓, TNF-α↓, NF-kB↓, IL6↓, survivin↓, BAX↑, Casp3↑, JAK2↓, STAT3↓, ERK↓,
1005- GI,    Ginger Constituent 6-Shogaol Inhibits Inflammation- and Angiogenesis-Related Cell Functions in Primary Human Endothelial Cells
- vitro+vivo, Nor, HUVECs
*NF-kB↓, *p65↓, *TLR4∅, *angioG↓, *TumCP↓, *VEGF↓, *Inflam↓, *ICAM-1↓, *VCAM-1↓, *E-sel↓, *p‑JNK↓, *HO-1↑,
4505- GLA,    Gamma linolenic acid suppresses hypoxia-induced proliferation and invasion of non-small cell lung cancer cells by inhibition of HIF1α
- in-vitro, NSCLC, Calu-1
TumCP↓, PCNA↓, Ki-67↓, MCM2↓, Bcl-2↓, BAX↑, cl‑Casp3↑, TumCMig↓, TumCI↓, Hif1a↓, VEGF↓,
4513- GLA,    Antineoplastic Effects of Gamma Linolenic Acid on Hepatocellular Carcinoma Cell Lines
- in-vitro, Liver, HUH7
TumCP↓, ROS↑, Apoptosis↑, HO-1↑, Trx↑, lipid-P↑, eff↓, MMP↓, DNAdam↑, selectivity↑,
855- Gra,    Antiproliferative activity of ionic liquid-graviola fruit extract against human breast cancer (MCF-7) cell lines using flow cytometry techniques
- in-vitro, BC, MCF-7
TumCG↓, TumCP↓, TumCCA↑, Apoptosis↑,
854- Gra,  AgNPs,    Green Synthesis of Silver Nanoparticles Using Annona muricata Extract as an Inducer of Apoptosis in Cancer Cells and Inhibitor for NLRP3 Inflammasome via Enhanced Autophagy
- vitro+vivo, AML, THP1 - in-vitro, AML, AMJ13 - vitro+vivo, lymphoma, HBL
TumCP↓, TumAuto↑, IL1↓, NLRP3↓, Apoptosis↑, mtDam↑, P53↑, LDH↓,
108- GSL,    A sesquiterpene lactone from Siegesbeckia glabrescens suppresses Hedgehog/Gli-mediated transcription in pancreatic cancer cells
- in-vitro, PC, PANC1 - in-vitro, PC, AsPC-1 - in-vitro, PC, C3H10T1/2
HH↓, Gli1↓, cycD1/CCND1↓, TumCP↓,
2523- H2,    Prospects of molecular hydrogen in cancer prevention and treatment
- Review, Var, NA
ROS↓, TumCP↓, TumMeta↓, AntiTum↑, GutMicro↑, Inflam↓, OS↑, radioP↑, selectivity↑, SOD↑, IL1β↑, IL8↑, TNF-α↑, neuroP↑,
2519- H2,    Hydrogen: an advanced and safest gas option for cancer treatment
- Review, Var, NA
antiOx↑, neuroP↓, BBB↑, toxicity∅, TumCP↓, Apoptosis↓, ROS↑, Hif1a↓, NF-kB↓, P53?, OS↑, chemoP↑,
2517- H2,    Molecular Hydrogen Enhances Proliferation of Cancer Cells That Exhibit Potent Mitochondrial Unfolded Protein Response
- in-vitro, Var, A549 - in-vitro, NA, HCT116 - in-vitro, NA, HeLa - in-vitro, NA, HepG2 - in-vitro, NA, HT1080 - in-vitro, NA, PC3 - in-vitro, NA, SH-SY5Y
TumCP↓, other↝, eff↝, mt-UPR↑,
1643- HCAs,    Mechanisms involved in the anticancer effects of sinapic acid
- Review, Var, NA
*BioAv↓, *toxicity↓, Dose∅, ROS⇅, ROS↑, Igs↑, TumCCA↑, TumAuto↑, eff↑, angioG↓, TumCI↓, TumMeta↓, EMT↓, Vim↓, MMP9↓, MMP2↓, Snail↓, E-cadherin↑, p‑Akt↓, GSK‐3β↓, TumCP↓, ChemoSen↑,
2082- HNK,    Revealing the role of honokiol in human glioma cells by RNA-seq analysis
- in-vitro, GBM, U87MG - in-vitro, GBM, U251
AntiCan↑, TumCP↑, TumAuto↑, Apoptosis↑, *BioAv↑, *neuroP↑, *NF-kB↑, MAPK↑, GPx4↑, Tf↑, BAX↑, Bcl-2↓, antiOx↑, Hif1a↓, Ferroptosis↑,
2879- HNK,    Honokiol Inhibits Lung Tumorigenesis through Inhibition of Mitochondrial Function
- in-vitro, Lung, H226 - in-vivo, NA, NA
tumCV↓, selectivity↑, TumCP↓, TumCCA↑, Apoptosis↑, mt-ROS↑, Casp3↑, Casp7↑, OCR↓, Cyt‑c↑, ATP↓, mitResp↓, AMP↑, AMPK↑,
2865- HNK,    Liposomal Honokiol induces ROS-mediated apoptosis via regulation of ERK/p38-MAPK signaling and autophagic inhibition in human medulloblastoma
- in-vitro, MB, DAOY - vitro+vivo, NA, NA
BioAv↓, BioAv↓, TumCP↓, selectivity↑, P53↑, P21↑, CDK4↓, cycD1/CCND1↓, mtDam↑, ROS↑, eff↓, Casp3↑, BAX↑, LC3II↑, Beclin-1↑, ATG7↑, p62↑, eff↑, ChemoSen↑, *toxicity↓,
2885- HNK,    Honokiol: a novel natural agent for cancer prevention and therapy
NF-kB↓, STAT3↓, EGFR↓, mTOR↓, BioAv↝, Inflam↓, TumCP↓, angioG↓, TumCI↓, TumMeta↓, cSrc↓, JAK1↓, JAK2↓, ERK↓, Akt↓, PTEN↑, ChemoSen↑, chemoP↑, COX2↓, PGE2↓, TNF-α↓, IL1β↓, IL6↓, Casp3↑, Casp8↑, Casp9↑, cl‑PARP↑, DNAdam↑, Cyt‑c↑, RadioS↑, RAS↓, BBB↑, BioAv↓, Half-Life↝, Half-Life↝, toxicity↓,
2895- HNK,    Mitochondria-Targeted Honokiol Confers a Striking Inhibitory Effect on Lung Cancer via Inhibiting Complex I Activity
- in-vitro, Lung, PC9
eff↑, TumCP↓, mt-ROS↑, Prx3↑, mt-STAT3↓, *toxicity∅, selectivity↑, ChemoSen↑,
2897- HNK,    Honokiol Inhibits Proliferation, Invasion and Induces Apoptosis Through Targeting Lyn Kinase in Human Lung Adenocarcinoma Cells
- in-vitro, Lung, PC9 - in-vitro, Lung, A549
TumCP↓, Apoptosis↑, EGFR↓, PI3K↓, Akt↓, STAT3↓, TumCI↓, TNF-α↑, NF-kB↓, VEGF↓, MMP9↓, COX2↓,
2898- HNK,    Honokiol Suppression of Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Gastric Cancer Cell Biological Activity and Its Mechanism
- in-vitro, GC, AGS - in-vitro, GC, NCI-N87 - in-vitro, BC, MGC803 - in-vitro, GC, SGC-7901
TumCP↓, Apoptosis↑, TumCI↓, TumCMig↓, HER2/EBBR2↓, TumCCA↑, PI3K↓, Akt↓, MMP9↓, P21↑,
4523- HNK,  MAG,  BA,    Honokiol-Magnolol-Baicalin Possesses Synergistic Anticancer Potential and Enhances the Efficacy of Anti-PD-1 Immunotherapy in Colorectal Cancer by Triggering GSDME-Dependent Pyroptosis
- in-vitro, CRC, HCT116 - in-vitro, CRC, LoVo - in-vivo, CRC, HCT116
AntiCan↑, eff↑, TumCP↓, TumCCA↓, cycD1/CCND1↓, Pyro↑, Apoptosis↑, cl‑GSDME↑, Bcl-2↓, Cyt‑c↑, Casp9↑, TumCG↓,
5053- HPT,  Rad,  Chemo,    Association of elevated reactive oxygen species and hyperthermia induced radiosensitivity in cancer stem-like cells
- in-vitro, Var, NA
CSCs↓, TumCP↓, ROS↑, RadioS↑,
4635- HT,    Hydroxytyrosol, a Component of Olive Oil for Breast Cancer Prevention in Women at High Risk of Cancer
- Trial, BC, NA
*Wnt↓, *NOTCH↓, *ROS↓, TumCP↓, CSCs↓,
4637- HT,    Comparative Cytotoxic Activity of Hydroxytyrosol and Its Semisynthetic Lipophilic Derivatives in Prostate Cancer Cells
- in-vitro, Nor, RWPE-1 - in-vitro, Pca, LNCaP - in-vitro, Pca, 22Rv1 - in-vitro, Pca, PC3
selectivity↑, TumCMig↓, p‑Akt↓, ROS↑, CSCs↓, CD44↓, TumCP↓,
4639- HT,    Hydroxytyrosol Induces Apoptosis, Cell Cycle Arrest and Suppresses Multiple Oncogenic Signaling Pathways in Prostate Cancer Cells
- in-vitro, Pca, LNCaP - in-vitro, Pca, C4-2B
TumCP↓, selectivity↑, TumCCA↑, cycD1/CCND1↓, cycE/CCNE↓, CDK2↓, CDK4↓, P21↑, p27↑, Apoptosis↑, Casp↑, cl‑PARP↑, Bax:Bcl2↑, p‑Akt↓, p‑STAT3↓, NF-kB↓, AR↓, ROS↑, *BioAv↓, *toxicity∅,
4642- HT,    Hydroxytyrosol, a natural molecule from olive oil, suppresses the growth of human hepatocellular carcinoma cells via inactivating AKT and nuclear factor-kappa B pathways
- in-vitro, HCC, HepG2 - NA, NA, Hep3B - NA, NA, SK-HEP-1
TumCP↓, TumCCA↑, Apoptosis↑, Akt↓, NF-kB↓, TumCG↓, angioG↓,
33- InA,    Inoscavin A, a pyrone compound isolated from a Sanghuangporus vaninii extract, inhibits colon cancer cell growth and induces cell apoptosis via the hedgehog signaling pathway
- vitro+vivo, Colon, NA
HH↓, Smo↓, TumCP↓, Apoptosis↑,
2180- itraC,    Repurposing Drugs in Oncology (ReDO)—itraconazole as an anti-cancer agent
- Review, Var, NA
Dose↝, toxicity↝, BioAv↑, Half-Life↝, BioAv↑, Dose↝, HH↓, TumAuto↑, Akt↓, mTOR↓, angioG↓, MDR1↓, TumCP↓, eff↑,
1167- IVM,    The river blindness drug Ivermectin and related macrocyclic lactones inhibit WNT-TCF pathway responses in human cancer
- vitro+vivo, NA, NA
Wnt↓, TCF↓, TumCP↓, Apoptosis↑, β-catenin/ZEB1↓, cycD1/CCND1↓,
1918- JG,    ROS -mediated p53 activation by juglone enhances apoptosis and autophagy in vivo and in vitro
- in-vitro, Liver, HepG2 - in-vivo, NA, NA
TumCG↓, TumCP↓, Apoptosis↑, TumAuto↑, AMPK↑, mTOR↑, P53↑, H2O2↑, ROS↑, toxicity↝, p62↓, DR5↑, Casp8↑, PARP↑, cl‑Casp3↑,
1923- JG,    Mechanism of Juglone-Induced Cell Cycle Arrest and Apoptosis in Ishikawa Human Endometrial Cancer Cells
- in-vitro, Endo, NA
TumCP↓, TumCCA↑, cycA1/CCNA1↓, ROS↑, P21↑, CDK2↓, CDK1↓, CDC25↓, Bcl-2↓, Bcl-xL↓, BAX↑, BAD↑, Cyt‑c↑,
1922- JG,    Juglone induces apoptosis of tumor stem-like cells through ROS-p38 pathway in glioblastoma
- in-vitro, GBM, U87MG
tumCV↓, TumCP↓, ROS↑, p‑p38↑, eff↓, Apoptosis↑, OS↑,
5117- JG,    https://pubmed.ncbi.nlm.nih.gov/31283929/
- vitro+vivo, Liver, NA
TumCG↓, TumCP↓, Apoptosis↑, TumAuto↑, AMPK↑, mTOR↑, P53↑, H2O2↑, ROS↑,
974- JG,    Juglone down-regulates the Akt-HIF-1α and VEGF signaling pathways and inhibits angiogenesis in MIA Paca-2 pancreatic cancer in vitro
- in-vitro, PC, MIA PaCa-2
Hif1a↓, VEGF↓, p‑Akt↓, TumCP↓, TumCI↓,
863- Lae,    Amygdalin inhibits the growth of renal cell carcinoma cells in vitro
- in-vitro, RCC, NA
TumCG↓, TumCP↓, TumCCA↑, CDK1↓, CycB/CCNB1↓, E-cadherin↝, N-cadherin↝,
2453- LE,    The Promoting Role of HK II in Tumor Development and the Research Progress of Its Inhibitors
- Review, Var, NA
HK2↓, PI3K↓, Akt↓, TumCP↓, Glycolysis↓,
6464- LIN,  1,8-Cin,    Anti-cancer mechanisms of linalool and 1,8-cineole in non-small cell lung cancer A549 cells
- in-vitro, NSCLC, A549 - in-vitro, Nor, WI38
TumCP↓, TumCCA↑, selectivity↑, ROS↑, MMP↓, eff↓, TumCMig↓, eff↑,
6479- LIN,    Anticancer effect of linalool via cancer-specific hydroxyl radical generation in human colon cancer
- in-vivo, Colon, HCT116
Apoptosis↑, ROS↑, lipid-P↑, selectivity↑, TumCP↓, *toxicity↓,
6481- LIN,    Linalool inhibits 22Rv1 prostate cancer cell proliferation and induces apoptosis
- in-vivo, Pca, 22Rv1
TumCP↓, Apoptosis↑, Ki-67↓, PCNA↓, TumCCA↑, MMP↓, TumCG↓,
1100- LT,    Luteolin, a flavonoid, as an anticancer agent: A review
- Review, NA, NA
TumCP↓, TumCCA↑, Apoptosis↑, EMT↓, E-cadherin↑, N-cadherin↓, Snail↓, Vim↓, ROS↑, ER Stress↑, mtDam↑, p‑eIF2α↝, p‑PERK↝, p‑CHOP↝, p‑ATF4↝, cl‑Casp12↝,
979- LT,    Luteolin Regulation of Estrogen Signaling and Cell Cycle Pathway Genes in MCF-7 Human Breast Cancer Cells
- in-vitro, BC, MCF-7
TumCP↓,
2906- LT,    Luteolin, a flavonoid with potentials for cancer prevention and therapy
- Review, Var, NA
*Inflam↓, AntiCan↑, antiOx⇅, Apoptosis↑, TumCP↓, TumMeta↓, angioG↓, PI3K↓, Akt↓, NF-kB↓, XIAP↓, P53↑, *ROS↓, *GSTA1↑, *GSR↑, *SOD↑, *Catalase↑, *other↓, ROS↑, Dose↝, chemoP↑, NF-kB↓, JNK↑, p27↑, P21↑, DR5↑, Casp↑, Fas↑, BAX↑, MAPK↓, CDK2↓, IGF-1↓, PDGF↓, EGFR↓, PKCδ↓, TOP1↓, TOP2↓, Bcl-xL↓, FASN↓, VEGF↓, VEGFR2↓, MMP9↓, Hif1a↓, FAK↓, MMP1↓, Twist↓, ERK↓, P450↓, CYP1A1↓, CYP1A2↓, TumCCA↑,
2909- LT,    Revisiting luteolin: An updated review on its anticancer potential
- Review, Var, NA
Apoptosis↑, TumCCA↑, angioG↓, TumMeta↓, TumCP↓, chemoP↑, MDR1↓,
2912- LT,    Luteolin: a flavonoid with a multifaceted anticancer potential
- Review, Var, NA
ROS↑, TumCCA↑, TumCP↓, angioG↓, ER Stress↑, mtDam↑, PERK↑, ATF4↑, eIF2α↑, cl‑Casp12↑, EMT↓, E-cadherin↑, N-cadherin↓, Vim↓, *neuroP↑, NF-kB↓, PI3K↓, Akt↑, XIAP↓, MMP↓, Ca+2↑, BAX↑, Casp3↑, Casp9↑, Bcl-2↓, Cyt‑c↑, IronCh↑, SOD↓, *ROS↓, *LDHA↑, *SOD↑, *GSH↑, *BioAv↓, Telomerase↓, cMyc↓, hTERT/TERT↓, DR5↑, Fas↑, FADD↑, BAD↑, BOK↑, BID↑, NAIP↓, Mcl-1↓, CDK2↓, CDK4↓, MAPK↓, AKT1↓, Akt2↓, *Beclin-1↓, Hif1a↓, LC3II↑, Beclin-1↑,
2913- LT,    Luteolin induces apoptosis by impairing mitochondrial function and targeting the intrinsic apoptosis pathway in gastric cancer cells
- in-vitro, GC, HGC27 - in-vitro, BC, MCF-7 - in-vitro, GC, MKN45
TumCP↓, MMP↓, Apoptosis↑, ROS↑, SOD↓, ATP↓, Bax:Bcl2↑, TumCCA↑,

Showing Research Papers: 451 to 500 of 811
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 811

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 3,   antiOx⇅, 1,   CYP1A1↓, 1,   Ferroptosis↑, 1,   GPx4↑, 1,   H2O2↑, 2,   HO-1↑, 1,   lipid-P↑, 2,   Prx3↑, 1,   ROS↓, 2,   ROS↑, 18,   ROS⇅, 1,   mt-ROS↑, 2,   SOD↓, 2,   SOD↑, 1,   Trx↑, 1,  

Metal & Cofactor Biology ⓘ

IronCh↑, 1,   Tf↑, 1,  

Mitochondria & Bioenergetics ⓘ

ATP↓, 2,   BOK↑, 1,   CDC25↓, 1,   mitResp↓, 1,   MMP↓, 6,   mtDam↑, 4,   OCR↓, 1,   XIAP↓, 2,  

Core Metabolism/Glycolysis ⓘ

AKT1↓, 1,   AMP↑, 1,   AMPK↑, 3,   ATG7↑, 1,   cMyc↓, 2,   FASN↓, 1,   Glycolysis↓, 1,   HK2↓, 1,   HMG-CoA↓, 1,   LDH↓, 1,  

Cell Death ⓘ

Akt↓, 7,   Akt↑, 1,   p‑Akt↓, 5,   Apoptosis?, 1,   Apoptosis↓, 1,   Apoptosis↑, 24,   BAD↑, 2,   BAX↑, 8,   Bax:Bcl2↑, 2,   Bcl-2↓, 7,   Bcl-xL↓, 2,   BID↑, 1,   Casp↑, 2,   Casp↝, 1,   cl‑Casp12↑, 1,   cl‑Casp12↝, 1,   Casp3↑, 6,   cl‑Casp3↑, 2,   Casp7↑, 1,   Casp8↑, 2,   Casp9↑, 4,   Cyt‑c↑, 5,   DR5↑, 3,   FADD↑, 1,   Fas↑, 2,   Ferroptosis↑, 1,   cl‑GSDME↑, 1,   hTERT/TERT↓, 1,   JNK↑, 1,   MAPK↓, 2,   MAPK↑, 1,   Mcl-1↓, 1,   NAIP↓, 1,   p27↑, 2,   p‑p38↑, 1,   Pyro↑, 1,   survivin↓, 1,   Telomerase↓, 1,  

Kinase & Signal Transduction ⓘ

cSrc↓, 1,   HER2/EBBR2↓, 1,  

Transcription & Epigenetics ⓘ

other↝, 2,   tumCV↓, 3,  

Protein Folding & ER Stress ⓘ

p‑CHOP↝, 1,   eIF2α↑, 1,   p‑eIF2α↝, 1,   ER Stress↑, 2,   PERK↑, 1,   p‑PERK↝, 1,   mt-UPR↑, 1,  

Autophagy & Lysosomes ⓘ

Beclin-1↓, 1,   Beclin-1↑, 2,   LC3II↑, 2,   p62↓, 1,   p62↑, 1,   TumAuto↑, 6,  

DNA Damage & Repair ⓘ

DNAdam↑, 2,   P53?, 1,   P53↑, 5,   P53↝, 1,   PARP↑, 1,   cl‑PARP↑, 2,   PCNA↓, 2,  

Cell Cycle & Senescence ⓘ

CDK1↓, 2,   CDK2↓, 4,   CDK4↓, 3,   cycA1/CCNA1↓, 1,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 7,   cycE/CCNE↓, 1,   P21↑, 5,   TumCCA↓, 1,   TumCCA↑, 16,  

Proliferation, Differentiation & Cell State ⓘ

CD44↓, 1,   CSCs↓, 4,   EMT↓, 3,   ERK↓, 3,   Gli1↓, 3,   GSK‐3β↓, 1,   HH↓, 5,   IGF-1↓, 1,   MCM2↓, 1,   mTOR↓, 2,   mTOR↑, 2,   PI3K↓, 5,   p‑PI3K↓, 1,   PTEN↑, 1,   RAS↓, 1,   Shh↓, 1,   Smo↓, 2,   STAT3↓, 4,   p‑STAT3↓, 1,   mt-STAT3↓, 1,   TCF↓, 1,   TOP1↓, 1,   TOP2↓, 1,   TumCG↓, 10,   TumCG↑, 1,   Wnt↓, 1,  

Migration ⓘ

Akt2↓, 1,   Ca+2↑, 1,   E-cadherin↑, 3,   E-cadherin↝, 1,   FAK↓, 1,   Ki-67↓, 2,   MMP1↓, 1,   MMP2↓, 2,   MMP9↓, 5,   N-cadherin↓, 2,   N-cadherin↝, 1,   PDGF↓, 1,   PKCδ↓, 1,   Snail↓, 2,   TumCI↓, 8,   TumCMig↓, 7,   TumCP↓, 48,   TumCP↑, 1,   TumMeta↓, 6,   Twist↓, 1,   Vim↓, 3,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 9,   ATF4↑, 1,   p‑ATF4↝, 1,   EGFR↓, 3,   EPR↑, 1,   Hif1a↓, 7,   VEGF↓, 4,   VEGFR2↓, 1,  

Barriers & Transport ⓘ

BBB↑, 2,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 3,   Igs↑, 1,   IL1↓, 1,   IL1β↓, 1,   IL1β↑, 1,   IL6↓, 2,   IL8↑, 1,   Inflam↓, 3,   JAK1↓, 1,   JAK2↓, 2,   NF-kB↓, 9,   PGE2↓, 1,   TNF-α↓, 2,   TNF-α↑, 2,  

Protein Aggregation ⓘ

NLRP3↓, 1,  

Hormonal & Nuclear Receptors ⓘ

AR↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 3,   BioAv↑, 2,   BioAv↝, 1,   ChemoSen↑, 5,   CYP1A2↓, 1,   Dose↝, 5,   Dose∅, 1,   eff↓, 4,   eff↑, 7,   eff↝, 1,   Half-Life↝, 3,   MDR1↓, 2,   P450↓, 1,   RadioS↑, 2,   selectivity↑, 10,  

Clinical Biomarkers ⓘ

AR↓, 1,   EGFR↓, 3,   GutMicro↑, 1,   HER2/EBBR2↓, 1,   hTERT/TERT↓, 1,   IL6↓, 2,   Ki-67↓, 2,   LDH↓, 1,  

Functional Outcomes ⓘ

AntiCan↑, 4,   AntiTum↑, 2,   chemoP↑, 4,   neuroP↓, 1,   neuroP↑, 1,   OS↑, 3,   radioP↑, 1,   toxicity↓, 1,   toxicity↝, 2,   toxicity∅, 1,  
Total Targets: 214

Pathway results for Effect on Normal Cells:


NA, unassigned ⓘ

AntiBio↑, 1,  

Redox & Oxidative Stress ⓘ

antiOx↓, 1,   antiOx↑, 1,   Catalase↑, 2,   GPx↑, 1,   GSH↑, 2,   GSR↑, 1,   GSTA1↑, 1,   GSTs↑, 1,   HO-1↑, 2,   NRF2↑, 1,   ROS↓, 3,   SOD↑, 3,   TBARS↓, 1,  

Core Metabolism/Glycolysis ⓘ

LDHA↑, 1,  

Cell Death ⓘ

iNOS↓, 1,   p‑JNK↓, 1,   survivin↓, 1,  

Transcription & Epigenetics ⓘ

other↓, 1,  

Autophagy & Lysosomes ⓘ

Beclin-1↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

NOTCH↓, 1,   Wnt↓, 1,  

Migration ⓘ

E-sel↓, 1,   TumCP↓, 1,   VCAM-1↓, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 1,   NO↓, 1,   VEGF↓, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   ICAM-1↓, 1,   IL1β↓, 1,   Inflam↓, 5,   NF-kB↓, 2,   NF-kB↑, 1,   p65↓, 1,   TLR4∅, 1,  

Synaptic & Neurotransmission ⓘ

AChE↓, 1,  

Protein Aggregation ⓘ

XO↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↓, 3,   BioAv↑, 1,  

Functional Outcomes ⓘ

AntiCan↑, 1,   memory↑, 1,   neuroP↑, 4,   toxicity↓, 3,   toxicity∅, 2,  
Total Targets: 45

Scientific Paper Hit Count for: TumCP, Tumor Cell proliferation
44 Curcumin
24 Thymoquinone
23 Quercetin
23 Shikonin
19 Magnetic Fields
18 EGCG (Epigallocatechin Gallate)
18 Berberine
18 Sulforaphane (mainly Broccoli)
17 Resveratrol
16 Baicalein
14 Silver-NanoParticles
14 Capsaicin
14 Phenethyl isothiocyanate
13 Apigenin (mainly Parsley)
12 Artemisinin
12 Propolis -bee glue
11 Ashwagandha(Withaferin A)
11 Astaxanthin
11 Boron
11 Crocetin
11 Lycopene
11 Nimbolide
10 Magnolol
10 Selenite (Sodium)
10 Silymarin (Milk Thistle) silibinin
10 Urolithin
9 Berbamine
9 Chrysin
9 Luteolin
8 Citric Acid
8 Radiotherapy/Radiation
8 Beta-Caryophyllene
8 Dandelion Root
8 Garcinol
8 Honokiol
7 Astragalus
7 Anethole/trans-Anethole
7 Cisplatin
7 chitosan
7 Bufalin/Huachansu
7 Eugenol
7 Piperlongumine
6 Boswellia (frankincense)
6 Carnosic acid
6 Rosmarinic acid
6 Celastrol
6 Carvone
6 Cucurbitacin
6 Ellagic acid
6 Phenylbutyrate
6 salinomycin
5 DTS(dibenzyl trisulphide) from Anamu
5 5-fluorouracil
5 Betulinic acid
5 Chemotherapy
5 Carvacrol
5 Metformin
5 Cinnamon
5 Copper and Cu NanoParticles
5 D-limonene
5 Emodin
5 Fisetin
5 Geraniol
5 Juglone
5 Vitamin K2
4 Allicin (mainly Garlic)
4 Gemcitabine (Gemzar)
4 Melatonin
4 Atorvastatin
4 brusatol
4 Chlorogenic acid
4 Chlorophyllin
4 Disulfiram
4 Gambogic Acid
4 HydroxyTyrosol
4 Magnetic Field Rotating
4 Piperine
4 Ursolic acid
3 1,8-Cineole
3 Alpha-Lipoic-Acid
3 Andrographis
3 Aspirin
3 Paclitaxel
3 immunotherapy
3 Docetaxel
3 α-Bisabolol / Chamomile oil
3 Butyrate
3 Thymol-Thymus vulgaris
3 Celecoxib
3 Chocolate
3 Photodynamic Therapy
3 Cyclopamine
3 diet Methionine-Restricted Diet
3 Galloflavin
3 Hydrogen Gas
3 Linalool
3 Methylene blue
3 Oleuropein
3 Propyl gallate
3 Plumbagin
3 Pterostilbene
3 Selenium
3 Terpinen-4-ol / Tea Tree Oil
3 Aflavin-3,3′-digallate
3 VitK3,menadione
3 Zerumbone
2 Auranofin
2 Ascorbyl Palmitate
2 Arctigenin
2 Baicalin
2 Biochanin A
2 Brucea javanica
2 Bacopa monnieri
2 Caffeic acid
2 Caffeic Acid Phenethyl Ester (CAPE)
2 Hydroxycinnamic-acid
2 Coenzyme Q10
2 Carica papaya leaf extract
2 Dichloroacetate
2 diet FMD Fasting Mimicking Diet
2 diet Short Term Fasting
2 Genistein (soy isoflavone)
2 Eurycomanone
2 Ferulic acid
2 Gallic acid
2 γ-linolenic acid (Borage Oil)
2 Graviola
2 Naringin
2 Niclosamide (Niclocide)
2 Psoralidin
2 α-Santalol/Sandalwood oil
2 Sulfasalazine
2 Salvia miltiorrhiza
2 Vitamin C (Ascorbic Acid)
2 Vitamin D3
1 2-DeoxyGlucose
1 Sorafenib (brand name Nexavar)
1 3-bromopyruvate
1 Glucose
1 SonoDynamic Therapy UltraSound
1 Zinc
1 Ajoene (compound of Garlic)
1 alpha Linolenic acid
1 Fennel Oil/Foeniculum vulgare
1 Aloe anthraquinones
1 beta-glucans
1 almonertinib
1 bempedoic acid
1 Bevacizumab (brand Avastin)
1 temozolomide
1 Bromelain
1 borneol
1 Bortezomib
1 Bruteridin(bergamot juice)
1 hydroxychloroquine
1 Cat’s Claw
1 Cynanbungeigenin C (CBC) and D (CBD)
1 Cannabidiol
1 Camptothecin
1 irinotecan
1 CUSP9
1 Dichloroacetophenone(2,2-)
1 Dasatinib/Phyrago
1 Deguelin
1 Date Fruit Extract
1 Evodiamine
1 Electrical Pulses
1 Exercise
1 Fucoidan
1 Fenbendazole
1 Vitamin E
1 Shilajit/Fulvic Acid
1 Ginkgo biloba
1 Germacranolide
1 Ginger/6-Shogaol/Gingerol
1 Siegesbeckia glabrescens
1 Hyperthermia
1 Inoscavin A
1 itraconazole
1 Ivermectin
1 Laetrile B17 Amygdalin
1 Licorice
1 Caffeine
1 doxorubicin
1 Mushroom Chaga
1 nicotinamide adenine dinucleotide
1 Bicarbonate(Sodium)
1 Oroxylin A
1 Oleocanthal
1 Proanthocyanidins
1 sericin
1 xanthohumol
1 Gold NanoParticles
1 Rutin
1 Oxaliplatin
1 Selenium NanoParticles
1 diet Plant based
1 Formononetin
1 Spermidine
1 tetrathiomolybdate
1 Tumor Treating Fields
1 Turmerones
1 Arsenic trioxide
1 Wogonin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:327  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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