Cancer Database Query Results

Scientific Papers found: Click to Expand⟱
4601- SeNPs,  AgNPs,    Antioxidant and hepatoprotective role of selenium against silver nanoparticles
- in-vivo, Nor, NA
*TAC↑, *CRP↓, *AST↓, *ALAT↓, *toxicity↓, *GSH↑, *SOD↑, *Catalase↑, *hepatoP↑,
4491- SeNPs,  Chit,  VitC,    Synthesis of a Bioactive Composition of Chitosan–Selenium Nanoparticles
- Study, NA, NA
*ROS↓, *selenoP↑, *antiOx↑, *Inflam↓, *Risk↓, *toxicity↓, AntiTum↑, Dose↝,
4504- SeNPs,  Chit,  FA,  doxoR,    pH-responsive selenium nanoparticles stabilized by folate-chitosan delivering doxorubicin for overcoming drug-resistant cancer cells
- in-vitro, Var, NA
ChemoSen↑, Apoptosis↑, Casp3↑, PARP↝,
4503- SeNPs,    Prophylactic supplementation with biogenic selenium nanoparticles mitigated intestinal barrier oxidative damage through suppressing epithelial-immune crosstalk with gut-on-a-chip
- in-vitro, Nor, NA
*selenoP↑, *ROS↓, *Inflam↓, *other↝,
4502- SeNPs,    Modulatory effects of selenium nanoparticles on gut microbiota and metabolites of juvenile Nile tilapia (Oreochromis niloticus) by microbiome-metabolomic analysis
- in-vivo, Nor, NA
*GutMicro↑, *Dose↝, *other↝, *toxicity↓, *BioAv↑, *Bacteria↓,
4501- SeNPs,    Mechanisms of the Cytotoxic Effect of Selenium Nanoparticles in Different Human Cancer Cell Lines
- in-vitro, GBM, A172 - in-vitro, Colon, Caco-2 - in-vitro, Pca, DU145 - in-vitro, BC, MCF-7 - in-vitro, Nor, L929
*BioAv↑, selectivity↑, AntiCan↑, Apoptosis↑, CHOP↑, GADD34↑, BIM↑, PUMA↑, Ca+2↝,
4462- SeNPs,  VitC,    Selenium nanoparticles: influence of reducing agents on particle stability and antibacterial activity at biogenic concentrations
- Study, Nor, NA
*Dose↝, *Bacteria↓,
4459- SeNPs,  VitC,  SSE,    Nano and mesosized selenium and its synthesis using the ascorbic acid route
*eff↑, *Dose↝, *Dose↝,
4463- SeNPs,  VitC,    Selenium nanoparticles: Synthesis, characterization and study of their cytotoxicity, antioxidant and antibacterial activity
- Study, Nor, NA
Dose↝,
4464- SeNPs,    Antioxidant Properties of Selenium Nanoparticles Synthesized Using Tea and Herb Water Extracts
- Study, NA, NA
*eff↑, *eff↝,
4465- SeNPs,  VitC,    Selenium nanoparticles: Synthesis, in-vitro cytotoxicity, antioxidant activity and interaction studies with ct-DNA and HSA, HHb and Cyt c serum proteins
- Study, NA, NA
*other↝, *eff↑, AntiCan↑, *Dose↝, *BioAv↑, *other↝,
4466- SeNPs,    Synthesis and Characterization of Selenium Nanoparticles and its Effects on in vitro Rumen Feed Degradation, Ruminal Parameters, and Total Gas Production
- Study, NA, NA
other?,
4467- SeNPs,  VitC,  Chit,    Nano-chitosan-coated, green-synthesized selenium nanoparticles as a novel antifungal agent against Sclerotinia sclerotiorum in vitro study
- Study, NA, NA
*Dose↝, *Dose↝,
4469- SeNPs,    Selenium Nanoparticles in Cancer Therapy: Unveiling Cytotoxic Mechanisms and Therapeutic Potential
- Review, Var, NA
antiOx↑, selectivity↑, eff↑, AntiCan↑, Apoptosis↑, ROS↑, MMP↓, Casp3↑, Casp9↑, AntiTum↑, TumCG↓, TumMeta↓, angioG↓, Cyt‑c↑, DNAdam↑, RadioS↑, BBB↑, *toxicity↓, ChemoSen↑,
4470- SeNPs,  Chit,    Synthesis and cytotoxic activities of selenium nanoparticles incorporated nano-chitosan
- in-vitro, CRC, HCT116 - in-vitro, Liver, HepG2 - in-vitro, BC, MCF-7
Dose↝, AntiCan↑, eff↑,
4471- SeNPs,    Green synthesis of selenium nanoparticles with extract of hawthorn fruit induced HepG2 cells apoptosis
- in-vitro, Liver, HepG2
eff↑, ROS↑, MMP↓, Casp9↑, Bcl-2↓, selectivity↑, Apoptosis↑,
4472- SeNPs,    Therapeutic potential of selenium nanoparticles
- Review, Var, NA
*ROS↓, *BioAv↑, *antiOx↑, toxicity↓, eff↑, *other↝, EPR↑, selectivity↑, eff↑, RadioS↑, eff↑, *Bacteria↓,
4473- SeNPs,    Anti-cancerous effect and biological evaluation of green synthesized Selenium nanoparticles on MCF-7 breast cancer and HUVEC cell lines
- in-vitro, BC, MCF-7 - in-vitro, Nor, HUVECs
AntiCan↑, selectivity↓, *Bacteria↓, *antiOx↑, *toxicity↓, ROS↑, tumCV↓,
4474- SeNPs,    In vitro growth of gut microbiota with selenium nanoparticles
*GutMicro↑,
4449- SeNPs,    PEG-nanolized ultrasmall selenium nanoparticles overcome drug resistance in hepatocellular carcinoma HepG2 cells through induction of mitochondria dysfunction
- in-vitro, Liver, HepG2
MMP↓, selectivity↑, Apoptosis↑, ROS↑,
4440- SeNPs,  AgNPs,    Selenium, silver, and gold nanoparticles: Emerging strategies for hepatic oxidative stress and inflammation reduction
- Review, NA, NA
*hepatoP↑, *antiOx↑, *Inflam↓, *ROS↓, *SOD↑, *GPx↑, *lipid-P↓,
4441- SeNPs,    The Role of Selenium Nanoparticles in the Treatment of Liver Pathologies of Various Natures
- Review, Nor, NA
*ROS↓, *hepatoP↑, *selenoP↑, *ALAT↓, *AST↓, *GSH↑, *GPx↑, *TNF-α↓, *IL6↓, *NF-kB↓, *p65↓, *Dose⇅,
4443- SeNPs,    Bioogenic selenium and its hepatoprotective activity
- in-vivo, LiverDam, NA
*hepatoP↑, *AST↓, *ALAT↓, *LDH↓, *lipid-P?,
4444- SeNPs,    Antioxidant and Hepatoprotective Efficiency of Selenium Nanoparticles Against Acetaminophen-Induced Hepatic Damage
- in-vivo, LiverDam, NA
*hepatoP↑, *ROS↓, *Catalase↑, *SOD↑, *GSH↑, *DNAdam↓,
4445- SeNPs,  DFE,    A comparative study on the hepatoprotective effect of selenium-nanoparticles and dates flesh extract on carbon tetrachloride induced liver damage in albino rats
- in-vivo, LiverDam, NA
*hepatoP↑, *antiOx↑, *AntiCan↑, *BioAv↑, *toxicity↓, *ROS↓, *MDA↓, *ALAT↓, *Albumin↑, *GSH↑, *SOD↑, *RenoP↑,
4446- SeNPs,    Antioxidant and Hepatoprotective Effects of Moringa oleifera-mediated Selenium Nanoparticles in Diabetic Rats.
- in-vivo, Diabetic, NA
*glucose↓, *antiOx↑, *GPx↑, *Catalase↑, *SOD↑, *ROS↓, *cardioP↑, *HDL↑, *LDL↓, *hepatoP↑, *TNF-α↓, *IL6↓, *IL1β↓, *lipid-P↓, *Inflam↓, *ALAT↓, *AST↓, *ALP↓, *Dose↝, *Dose↝,
4448- SeNPs,    Selenium Nanoparticles: A Comprehensive Examination of Synthesis Techniques and Their Diverse Applications in Medical Research and Toxicology Studies
- Review, Nor, NA
*toxicity↓, *toxicity↓, selectivity↑, *antiOx↑, *cognitive↑, *other↝, TumCCA↑,
4461- SeNPs,  VitC,    Synthesis, Characterization, and Cytotoxic Evaluation of Selenium Nanoparticles
*Dose?,
4450- SeNPs,    Functionalized selenium nanoparticles with nephroprotective activity, the important roles of ROS-mediated signaling pathways
- in-vitro, Kidney, NA
antiOx↑, *ROS↓, RenoP↑,
4451- SeNPs,    Effects of chitosan-stabilized selenium nanoparticles on cell proliferation, apoptosis and cell cycle pattern in HepG2 cells: comparison with other selenospecies
- in-vitro, Liver, HepG2
*antiOx↑, Apoptosis↑, TumCCA↑,
4452- SeNPs,  Chit,    Antioxidant capacities of the selenium nanoparticles stabilized by chitosan
- in-vitro, Nor, 3T3
*toxicity↓, *antiOx↑, *GPx↑, *ROS↓,
4453- SeNPs,    Selenium Nanoparticles: Green Synthesis and Biomedical Application
- Review, NA, NA
*toxicity↓, *Bacteria↓, ROS↑, MMP↓, ER Stress↑, P53↑, Apoptosis↑, Casp9↑, DNAdam↑, TumCCA↑, eff↑, Catalase↓, SOD↓, GSH↓, selectivity↓, selectivity↑, PCNA↓, eff↑, *ALAT↓, *AST↓, *ALP↓, *creat↓, *Inflam↓, *toxicity↓, selectivity↑,
4457- SeNPs,    Selenium nanoparticles: a review on synthesis and biomedical applications
- Review, Var, NA - NA, Diabetic, NA
*BioAv↑, *toxicity↓, *eff↑, chemoPv↑, *Inflam↓, antiOx↑, *selenoP↑, *ROS↓, *Dose↝, AntiCan↑, *Bacteria↓, eff↑, DNAdam↑, selectivity↑, *eff↑,
4458- SeNPs,    Selenium Nanoparticles for Antioxidant Activity and Selenium Enrichment in Plants
*Dose↝, *eff↑, *Dose↝,
4460- SeNPs,  VitC,    Ascorbic acid-mediated selenium nanoparticles as potential antihyperuricemic, antioxidant, anticoagulant, and thrombolytic agents
Dose?,
4189- Sesame,    Sesame oil mitigates memory impairment, oxidative stress, and neurodegeneration in a rat model of Alzheimer's disease. A pivotal role of NF-κB/p38MAPK/BDNF/PPAR-γ pathways
- in-vivo, AD, NA
*TNF-α↓, *IL1β↓, *ROS↓, *BDNF↑, *neuroP↑, *cognitive↑,
4190- Sesame,    Sesame Seeds: A Nutrient-Rich Superfood
- Review, NA, NA
*antiOx↑, *LDL↓, *Aβ↓, *TNF-α↓, *SOD↑, *SIRT1↑, *Catalase↑, *GSH↑, *MDA↓, *GSTs↑, *IL4↑, *GPx↑, *COX2↓, *PGE2↓, *NO↓, CDK2↑, COX2↑, MMP9↑, ICAM-1↓, *BDNF↑, *PPARγ↑, *AChE↓, *Inflam↓, *HO-1↑, *NF-kB↓, *ROS↓,
4200- SFN,    Sulforaphane activates anti-inflammatory microglia, modulating stress resilience associated with BDNF transcription
- in-vitro, NA, NA
*NRF2↑, *BDNF↑, *Inflam↓,
4202- SFN,    Regulation of BDNF transcription by Nrf2 and MeCP2 ameliorates MPTP-induced neurotoxicity
- Review, Park, NA
*NRF2↑, *BDNF↑,
4201- SFN,    Activation of BDNF by transcription factor Nrf2 contributes to antidepressant-like actions in rodents
- in-vivo, NA, NA
*NRF2↑, *BDNF↑, *HDAC2↓, *Mood↑,
4199- SFN,    Sulforaphane and Brain Health: From Pathways of Action to Effects on Specific Disorders
- Review, AD, NA - Review, Park, NA
*BBB↑, *BDNF↑, *neuroG↑, *NRF2↑, *HO-1↑, *Catalase↑, *SOD↑, *HSPs↑, *GSTs↑, *Trx↑, *GPx↑, *GSR↑, *GSH↑, *NQO1↑, *GutMicro↑, *Inflam↓, *neuroP↑,
4198- SFN,    Sulforaphane epigenetically enhances neuronal BDNF expression and TrkB signaling pathways
- vitro+vivo, AD, NA
*TrkB↑, *CREB↑, CaMKII ↑, *ERK↑, *ac‑H3↑, *ac‑H4↑, *HDAC↓, *HDAC2↓, *BDNF↑,
3200- SFN,    Sulforaphane suppresses the activity of sterol regulatory element-binding proteins (SREBPs) by promoting SREBP precursor degradation
- in-vitro, Liver, HUH7
FASN↓, ACC↓, SREBP1↓,
3199- SFN,    Sulforaphane improves chemotherapy efficacy by targeting cancer stem cell-like properties via the miR-124/IL-6R/STAT3 axis
- in-vitro, GC, NA
CSCs↓, CD133↓, BMI1↓, Nanog↓, Nestin↓,
3198- SFN,    Sulforaphane and TRAIL induce a synergistic elimination of advanced prostate cancer stem-like cells
- in-vitro, Pca, NA
Nanog↓, SOX2↓, E-cadherin↓, Snail↓, VEGFR2↓, Diff↓, TumCMig↓, EMT↓, CXCR4↓, NOTCH1↓, ALDH1A1↓, CSCs↓, eff↑,
3180- SFN,    Exploring the therapeutic effects of sulforaphane: an in-depth review on endoplasmic reticulum stress modulation across different disease contexts
- Review, Var, NA
*cardioP↑, *ER Stress↓, GRP78/BiP↑, XBP-1↑, Apoptosis↑, *NRF2↑, UPR↑,
3181- SFN,    Effect of sulforaphane on protein expression of Bip/GRP78 and caspase-12 in human hapetocelluar carcinoma HepG-2 cells
- in-vitro, HCC, HepG2
GRP78/BiP↑, Casp12↑, Apoptosis↑, ER Stress↑,
3197- SFN,    Sulforaphane Inhibits Self-renewal of Lung Cancer Stem Cells Through the Modulation of Polyhomeotic Homolog 3 and Sonic Hedgehog Signaling Pathways
- in-vitro, Lung, A549 - in-vitro, Lung, H460
TumCP↓, CSCs↓, Shh↓, Smo↓, Gli1↓,
3196- SFN,    Sulforaphane eradicates pancreatic cancer stem cells by NF-κB
- Review, PC, NA
CSCs↓, NF-kB↓,
3195- SFN,    AKT1/HK2 Axis-mediated Glucose Metabolism: A Novel Therapeutic Target of Sulforaphane in Bladder Cancer
- in-vitro, Bladder, UMUC3
ATP↓, Glycolysis↓, OXPHOS↓, HK2↓, PDH↓, AKT1↓, p‑Akt↓,

Showing Research Papers: 4951 to 5000 of 5925
Prev Page 100 of 119 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 5925

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 3,   Catalase↓, 1,   GSH↓, 1,   OXPHOS↓, 1,   ROS↑, 5,   SOD↓, 1,  

Mitochondria & Bioenergetics ⓘ

ATP↓, 1,   MMP↓, 4,  

Core Metabolism/Glycolysis ⓘ

ACC↓, 1,   AKT1↓, 1,   FASN↓, 1,   Glycolysis↓, 1,   HK2↓, 1,   PDH↓, 1,   SREBP1↓, 1,  

Cell Death ⓘ

p‑Akt↓, 1,   Apoptosis↑, 9,   Bcl-2↓, 1,   BIM↑, 1,   Casp12↑, 1,   Casp3↑, 2,   Casp9↑, 3,   Cyt‑c↑, 1,   GADD34↑, 1,   PUMA↑, 1,  

Kinase & Signal Transduction ⓘ

CaMKII ↑, 1,  

Transcription & Epigenetics ⓘ

other?, 1,   tumCV↓, 1,  

Protein Folding & ER Stress ⓘ

CHOP↑, 1,   ER Stress↑, 2,   GRP78/BiP↑, 2,   UPR↑, 1,   XBP-1↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↑, 3,   P53↑, 1,   PARP↝, 1,   PCNA↓, 1,  

Cell Cycle & Senescence ⓘ

CDK2↑, 1,   TumCCA↑, 3,  

Proliferation, Differentiation & Cell State ⓘ

ALDH1A1↓, 1,   BMI1↓, 1,   CD133↓, 1,   CSCs↓, 4,   Diff↓, 1,   EMT↓, 1,   Gli1↓, 1,   Nanog↓, 2,   Nestin↓, 1,   NOTCH1↓, 1,   Shh↓, 1,   Smo↓, 1,   SOX2↓, 1,   TumCG↓, 1,  

Migration ⓘ

Ca+2↝, 1,   E-cadherin↓, 1,   MMP9↑, 1,   Snail↓, 1,   TumCMig↓, 1,   TumCP↓, 1,   TumMeta↓, 1,  

Angiogenesis & Vasculature ⓘ

angioG↓, 1,   EPR↑, 1,   VEGFR2↓, 1,  

Barriers & Transport ⓘ

BBB↑, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↑, 1,   CXCR4↓, 1,   ICAM-1↓, 1,   NF-kB↓, 1,  

Drug Metabolism & Resistance ⓘ

ChemoSen↑, 2,   Dose?, 1,   Dose↝, 3,   eff↑, 10,   RadioS↑, 2,   selectivity↓, 2,   selectivity↑, 9,  

Functional Outcomes ⓘ

AntiCan↑, 6,   AntiTum↑, 2,   chemoPv↑, 1,   RenoP↑, 1,   toxicity↓, 1,  
Total Targets: 80

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress ⓘ

antiOx↑, 10,   Catalase↑, 5,   GPx↑, 6,   GSH↑, 6,   GSR↑, 1,   GSTs↑, 2,   HDL↑, 1,   HO-1↑, 2,   lipid-P?, 1,   lipid-P↓, 2,   MDA↓, 2,   NQO1↑, 1,   NRF2↑, 5,   ROS↓, 13,   selenoP↑, 4,   SOD↑, 7,   TAC↑, 1,   Trx↑, 1,  

Core Metabolism/Glycolysis ⓘ

ALAT↓, 6,   CREB↑, 1,   glucose↓, 1,   LDH↓, 1,   LDL↓, 2,   PPARγ↑, 1,   SIRT1↑, 1,  

Transcription & Epigenetics ⓘ

ac‑H3↑, 1,   ac‑H4↑, 1,   other↝, 6,  

Protein Folding & ER Stress ⓘ

ER Stress↓, 1,   HSPs↑, 1,  

DNA Damage & Repair ⓘ

DNAdam↓, 1,  

Proliferation, Differentiation & Cell State ⓘ

ERK↑, 1,   HDAC↓, 1,   HDAC2↓, 2,   neuroG↑, 1,  

Angiogenesis & Vasculature ⓘ

NO↓, 1,  

Barriers & Transport ⓘ

BBB↑, 1,  

Immune & Inflammatory Signaling ⓘ

COX2↓, 1,   CRP↓, 1,   IL1β↓, 2,   IL4↑, 1,   IL6↓, 2,   Inflam↓, 9,   NF-kB↓, 2,   p65↓, 1,   PGE2↓, 1,   TNF-α↓, 4,  

Synaptic & Neurotransmission ⓘ

AChE↓, 1,   BDNF↑, 7,   TrkB↑, 1,  

Protein Aggregation ⓘ

Aβ↓, 1,  

Drug Metabolism & Resistance ⓘ

BioAv↑, 6,   Dose?, 1,   Dose⇅, 1,   Dose↝, 12,   eff↑, 6,   eff↝, 1,  

Clinical Biomarkers ⓘ

ALAT↓, 6,   Albumin↑, 1,   ALP↓, 2,   AST↓, 5,   creat↓, 1,   CRP↓, 1,   GutMicro↑, 3,   IL6↓, 2,   LDH↓, 1,  

Functional Outcomes ⓘ

AntiCan↑, 1,   cardioP↑, 2,   cognitive↑, 2,   hepatoP↑, 7,   Mood↑, 1,   neuroP↑, 2,   RenoP↑, 1,   Risk↓, 1,   toxicity↓, 12,  

Infection & Microbiome ⓘ

Bacteria↓, 6,  
Total Targets: 76

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:%  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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