| 7704- | IP6, | Inositol hexaphosphate hydrolysate competitively binds to AKT to inhibit the proliferation of colon carcinoma |
| - | in-vitro, | CRC, | SW-620 |
| 7705- | IP6, | Inositol hexaphosphate (InsP6) as an effective topical treatment for patients receiving adjuvant chemotherapy after breast surgery |
| 1293- | IP6, | Inositol Hexaphosphate Inhibits Growth and Induces G1 Arrest and Apoptotic Death of Androgen-Dependent Human Prostate Carcinoma LNCaP Cells |
| - | vitro+vivo, | Pca, | LNCaP |
| 1088- | IP6, | Preventive Inositol Hexaphosphate Extracted from Rice Bran Inhibits Colorectal Cancer through Involvement of Wnt/β-Catenin and COX-2 Pathways |
| - | in-vivo, | CRC, | NA |
| 7743- | ISL, | Pharmacokinetics, biodistribution and bioavailability of isoliquiritigenin after intravenous and oral administration |
| - | in-vivo, | Nor, | NA |
| 7750- | ISL, | Isoliquiritigenin in Breast Cancer: A Systematic Review of Its Preventive and Anti-metastatic Mechanisms |
| - | Review, | BC, | NA |
| 7753- | ISL, | LE, | Pharmacokinetic Interactions of a Licorice Dietary Supplement with Cytochrome P450 Enzymes in Female Participants |
| - | in-vivo, | Nor, | NA |
| 7751- | ISL, | LE, | Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents |
| 7752- | ISL, | Isoliquiritigenin showed strong inhibitory effects towards multiple UDP-glucuronosyltransferase (UGT) isoform-catalyzed 4-methylumbelliferone (4-MU) glucuronidation |
| - | in-vitro, | Nor, | NA |
| 7749- | ISL, | Inhibition of COX-2, mPGES-1 and CYP4A by isoliquiritigenin blocks the angiogenic Akt signaling in glioma through ceRNA effect of miR-194-5p and lncRNA NEAT1 |
| - | in-vitro, | GBM, | U87MG |
| 7744- | ISL, | Isoliquiritigenin suppresses fatty acid synthesis and cancer cell migration in anaplastic thyroid carcinoma through AMPK/SREBF1 pathway |
| - | vitro+vivo, | Thyroid, | NA |
| 7745- | ISL, | Isoliquiritigenin inhibits colorectal cancer progression by targeting the FGFR4/FASN mediated lipid metabolism pathway |
| - | in-vitro, | CRC, | NA |
| 7746- | ISL, | Isoliquiritigenin Inhibits the Growth of Colorectal Cancer Cells through the ESR2/PI3K/AKT Signalling Pathway |
| - | vitro+vivo, | CRC, | SW480 | - | vitro+vivo, | CRC, | HCT116 |
| 7747- | ISL, | Isoliquiritigenin Induces Apoptosis via ROS-Mediated Inhibition of p38/mTOR/STAT3 Pathway in Human Melanoma Cells |
| - | in-vitro, | Melanoma, | SK-MEL-28 |
| 7748- | ISL, | GEM, | Isoliquiritigenin combined with gemcitabine inhibited lung cancer by suppressing JAK2/STAT3 signaling via lncRNA-p21/miRNA-4534 axis |
| - | NA, | Lung, | NA |
| 7754- | ISL, | Isoliquiritigenin Confers Neuroprotection and Alleviates Amyloid-β42-Induced Neuroinflammation in Microglia by Regulating the Nrf2/NF-κB Signaling |
| - | in-vitro, | AD, | BV2 |
| 7755- | ISL, | Isoliquiritigenin attenuated cognitive impairment, cerebral tau phosphorylation and oxidative stress in a streptozotocin-induced mouse model of Alzheimer's disease |
| - | in-vivo, | AD, | NA |
| 7756- | ISL, | Dietary compound isoliquiritigenin inhibits breast cancer neoangiogenesis via VEGF/VEGFR-2 signaling pathway |
| - | vitro+vivo, | BC, | MCF7 | - | vitro+vivo, | BC, | MDA-MB-231 |
| 7757- | ISL, | Isoliquiritigenin Suppresses Oral Squamous Cell Carcinoma Progression by Targeting FABP5-Mediated Lipid Metabolism: Association with the circPOLB/miR-548ae-3p/C-MYC Axis |
| - | in-vitro, | Oral, | NA |
| 7758- | ISL, | Targeting the JAK/STAT pathway with isoliquiritigenin in ovarian cancer: molecular mechanisms and therapeutic implications |
| - | Review, | Ovarian, | NA |
| 7759- | ISL, | Rad, | Isoliquiritigenin, a Bioactive Blood Component Derived from Licorice, Activates Nrf2 Enzymes to Confer Protection Against Radiation-Induced Nerve Injury |
| - | vitro+vivo, | Nor, | PC12 |
| 7760- | ISL, | Pharmacological Potentials and Delivery Strategies of Isoliquiritigenin: Challenges and Advances in Enhancing Bioavailability |
| - | Review, | Nor, | NA |
| 7761- | ISL, | Targeting digestive system cancers with isoliquiritigenin: a comprehensive review of antitumor mechanisms |
| - | Review, | Var, | NA |
| 7762- | ISL, | Isoliquiritigenin reduces brain metastasis by circNAV3-ST6GALNAC5-EGFR axis in triple-negative breast cancer |
| - | in-vivo, | BC, | NA |
| 7763- | ISL, | Harnessing Liquiritigenin: A Flavonoid-Based Approach for the Prevention and Treatment of Cancer |
| 7764- | ISL, | Licorice Extract Isoliquiritigenin Increased Cytosol Calcium and Induced Apoptosis in Colon Cancer Cells via Transient Receptor Potential Vanilloid‐1 |
| - | in-vitro, | CRC, | HT-29 | - | in-vitro, | CRC, | HCT116 |
| 8280- | ISL, | ISL Induces Apoptosis and Autophagy in Hepatocellular Carcinoma via Downregulation of PI3K/AKT/mTOR Pathway in vivo and in vitro |
| - | vitro+vivo, | HCC, | SMMC-7721 cell |
| 7766- | ISL, | Isoliquiritigenin alleviates myocardial ischemia-reperfusion injury by regulating the Nrf2/HO-1/SLC7a11/GPX4 axis in mice |
| - | in-vivo, | Stroke, | NA |
| 7765- | ISL, | Isoliquiritigenin as a modulator of the Nrf2 signaling pathway: potential therapeutic implications |
| - | Review, | Var, | NA |
| 7782- | ISL, | BUT, | SCP, | Butein, isoliquiritigenin, and scopoletin attenuate neurodegeneration via antioxidant enzymes and SIRT1/ADAM10 signaling pathway |
| - | in-vitro, | AD, | SH-SY5Y |
| 7783- | ISL, | Isoliquiritigenin Inhibits Ovarian Cancer Metastasis by Reversing Epithelial-to-Mesenchymal Transition |
| - | vitro+vivo, | Ovarian, | SKOV3 | - | in-vitro, | Ovarian, | OVCAR-3 |
| 7781- | ISL, | Perspectives on the Role of Isoliquiritigenin in Cancer |
| - | Review, | Var, | NA |
| 7784- | ISL, | Isoliquiritigenin attenuates lipopolysaccharide-induced cognitive impairment through antioxidant and anti-inflammatory activity |
| - | in-vivo, | AD, | NA |
| 7780- | ISL, | Isoliquiritigenin alleviates LPS/ D-GalN-induced acute liver failure by activating the PGC-1α/ Nrf2 pathway to reduce oxidative stress and inflammatory response |
| - | in-vivo, | Nor, | NA |
| 7777- | ISL, | Isoliquiritigenin induces HMOX1 and GPX4-mediated ferroptosis in gallbladder cancer cells |
| - | vitro+vivo, | Gall, | SGC996 |
| 7785- | ISL, | Enhancement of Oral Bioavailability and Anti-hyperuricemic Activity of Isoliquiritigenin via Self-Microemulsifying Drug Delivery System |
| - | in-vivo, | Nor, | NA |
| 7786- | ISL, | Isoliquiritigenin exhibits anti-proliferative properties in the pituitary independent of estrogen receptor function |
| 7787- | ISL, | Dietary compound isoliquiritigenin targets GRP78 to chemosensitize breast cancer stem cells via β-catenin/ABCG2 signaling |
| - | in-vitro, | BC, | NA |
| 7788- | ISL, | Syntheses and evaluation of novel isoliquiritigenin derivatives as potential dual inhibitors for amyloid-beta aggregation and 5-lipoxygenase |
| - | in-vitro, | AD, | NA |
| 7790- | ISL, | Dietary administration of the licorice flavonoid isoliquiritigenin deters the growth of MCF-7 cells overexpressing aromatase |
| - | vitro+vivo, | BC, | MCF7 |
| 7789- | ISL, | Cancer Chemopreventive Activity and Metabolism of Isoliquiritigenin, a Compound Found in Licorice |
| - | Review, | Nor, | NA |
| 7779- | ISL, | Isoliquiritigenin-mediated miR-23a-3p inhibition activates PGC-1α to alleviate alcoholic liver injury |
| - | in-vivo, | Alcohol, | NA |
| 7778- | ISL, | Isoliquiritigenin, a potent human monoamine oxidase inhibitor, modulates dopamine D1, D3, and vasopressin V1A receptors |
| - | Study, | Park, | NA | - | Study, | AD, | NA |
| 7736- | isoFl, | Dietary isoflavone intake and all-cause mortality in breast cancer survivors: The Breast Cancer Family Registry |
| - | Review, | BC, | NA |
| 7741- | isoFl, | Lyco, | SIL, | Randomized, double-blind, placebo-controlled crossover study in men with prostate cancer and rising PSA: effectiveness of a dietary supplement |
| - | Trial, | Pca, | NA |
| 7740- | isoFl, | Effect of soy protein isolate supplementation on biochemical recurrence of prostate cancer after radical prostatectomy: a randomized trial |
| - | Trial, | Pca, | NA |
| 7739- | isoFl, | Soy, red clover, and isoflavones and breast cancer: a systematic review |
| - | Review, | BC, | NA |
| 7738- | isoFl, | Consumption of soy isoflavone enriched bread in men with prostate cancer is associated with reduced pro-inflammatory cytokines and immune suppressive cells |
| - | Trial, | Pca, | NA |
| 7737- | isoFl, | An updated review of dietary isoflavones: Nutrition, processing, bioavailability and impacts on human health |
| - | Review, | Nor, | NA |
| 7735- | isoFl, | Soy Isoflavones in Integrative Oncology: Increased Efficacy and Decreased Toxicity of Cancer Therapy |
| - | Review, | Var, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:% State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid