| Source: |
| Type: |
| Toxicity |
| 7990- | itraC, | A Novel Approach to Reducing Chemoresistance in Advanced Ovarian Cancer: The Effect of Itraconazole-A Single-Institution Randomized Placebo-Controlled Trial |
| - | Trial, | Ovarian, | NA |
| 7988- | itraC, | Itraconazole as a Noncastrating Treatment for Biochemically Recurrent Prostate Cancer: A Phase 2 Study |
| - | Trial, | Pca, | NA |
| 7987- | itraC, | Repurposing itraconazole as a treatment for advanced prostate cancer: a noncomparative randomized phase II trial in men with metastatic castration-resistant prostate cancer |
| - | Trial, | Pca, | NA |
| 8036- | IVM, | Ivermectin inhibits the growth of ESCC by activating the ATF4-mediated endoplasmic reticulum stress-autophagy pathway |
| - | in-vitro, | ESCC, | KYSE-30 |
| 8039- | IVM, | Ivermectin-Induced Apoptotic Cell Death in Human SH-SY5Y Cells Involves the Activation of Oxidative Stress and Mitochondrial Pathway and Akt/mTOR-Pathway-Mediated Autophagy |
| - | in-vitro, | neuroblastoma, | SH-SY5Y |
| 7889- | IVT, | Prevention of cellular ROS damage by isovitexin and related flavonoids |
| - | in-vitro, | Nor, | NA |
| 1918- | JG, | ROS -mediated p53 activation by juglone enhances apoptosis and autophagy in vivo and in vitro |
| - | in-vitro, | Liver, | HepG2 | - | in-vivo, | NA, | NA |
| 8071- | KAE, | Cellular reprogramming and signaling control by kaempferol in colorectal cancer |
| - | Review, | CRC, | NA |
| 8058- | KAE, | A randomized, placebo‐controlled trial evaluating the safety of excessive administration of kaempferol aglycone |
| - | Trial, | Nor, | NA |
| 8064- | KAE, | Kaempferol Inhibits Pancreatic Cancer Cell Growth and Migration through the Blockade of EGFR-Related Pathway In Vitro |
| - | in-vitro, | PC, | MIA PaCa-2 | - | in-vitro, | PC, | PANC1 | - | in-vitro, | PC, | SNU-213 |
| 8055- | KAE, | Molecular Mechanisms of the Anticancer Activity of the Flavonoid Kaempferol: A Comprehensive Review |
| - | Review, | Var, | NA |
| 8108- | L-Orn, | Safety assessment of L-ornithine oral intake in healthy subjects: a systematic review |
| - | Review, | Nor, | NA |
| 9059- | L-THE, | Cognitive and affective effects of L-Theanine: a systematic review and meta-analysis of 31 randomized trials |
| - | Review, | AD, | NA |
| 9060- | L-THE, | Effects of L-theanine on cognition, mood and sleep: evidence from human trials |
| - | Review, | AD, | NA |
| 9071- | L-THE, | Effects of Chronic L-theanine on Stress-related Symptoms and Cognitive Function in a Non-clinical Population: A Randomized Controlled Trial |
| - | Trial, | Nor, | NA |
| 9006- | L-THE, | Theanine from tea and its semi-synthetic derivative TBrC suppress human cervical cancer growth and migration by inhibiting EGFR/Met-Akt/NF-κB signaling |
| - | vitro+vivo, | Cerv, | HeLa |
| 865- | Lae, | Amygdalin: A Review on Its Characteristics, Antioxidant Potential, Gastrointestinal Microbiota Intervention, Anticancer Therapeutic and Mechanisms, Toxicity, and Encapsulation |
| - | Review, | Var, | NA |
| 8146- | Lae, | Laetrile treatment for cancer |
| - | Review, | Var, | NA |
| 8173- | Lap, | Tras, | Efficacy and safety of lapatinib and trastuzumab for HER2-positive breast cancer: a systematic review and meta-analysis of randomised controlled trials |
| - | Review, | BC, | NA |
| 8169- | Lap, | Lapatinib Activates the Kelch-Like ECH-Associated Protein 1-Nuclear Factor Erythroid 2-Related Factor 2 Pathway in HepG2 Cells |
| - | in-vitro, | Liver, | HepG2 |
| 8166- | LapC, | Enhanced antitumor efficacy of lapachol-loaded nanoemulsion in breast cancer tumor model |
| - | vitro+vivo, | BC, | NA |
| 8176- | Las, | In Vitro and In Vivo Anti-Cancer Activity of Lasiokaurin in a Triple-Negative Breast Cancer Model |
| - | vitro+vivo, | BC, | NA |
| 8219- | LCA, | Licochalcone A Ameliorates Cognitive Dysfunction in an Alzheimer's Disease Model by Inhibiting Endoplasmic Reticulum Stress-Mediated Apoptosis |
| - | in-vivo, | AD, | NA |
| 8233- | LCA, | Licochalcone A induces cell cycle arrest and apoptosis via suppressing MAPK signaling pathway and the expression of FBXO5 in lung squamous cell cancer |
| - | in-vitro, | Lung, | NA |
| 8232- | LCA, | Licochalcone A induces G2/M phase arrest and apoptosis via regulating p53 pathways in esophageal cancer: In-vitro and in-vivo study |
| - | vitro+vivo, | ESCC, | NA |
| 8335- | LDN, | The opioid growth factor (OGF) and low dose naltrexone (LDN) suppress human ovarian cancer progression in mice |
| - | vitro+vivo, | Ovarian, | SKOV3 |
| 8341- | LDN, | Low-Dose Naltrexone as an Adjuvant in Combined Anticancer Therapy |
| - | Review, | Var, | NA |
| 8338- | LDN, | Low-dose naltrexone plays antineoplastic role in cervical cancer progression through suppressing PI3K/AKT/mTOR pathway |
| - | vitro+vivo, | Cerv, | HeLa | - | in-vitro, | Cerv, | SiHa |
| 8290- | LE, | Licoricidin, an Active Compound in the Hexane/Ethanol Extract of Glycyrrhiza uralensis, Inhibits Lung Metastasis of 4T1 Murine Mammary Carcinoma Cells |
| - | vitro+vivo, | Pca, | DU145 |
| 8236- | LE, | Licorice (Glycyrrhiza glabra L.)-Derived Phytochemicals Target Multiple Signaling Pathways to Confer Oncopreventive and Oncotherapeutic Effects |
| - | Review, | Var, | NA |
| 8273- | LE, | A Systematic Review of the Effect of Licorice on Head and Neck Chemotherapy- and Radiotherapy-Induced Mucositis |
| - | Review, | HNSCC, | NA |
| 8278- | LE, | Glycyrrhiza glabra (Licorice): A Comprehensive Review on Its Phytochemistry, Biological Activities, Clinical Evidence and Toxicology |
| - | Review, | Var, | NA |
| 8128- | LF, | Phase 2 trial of talactoferrin in previously treated patients with metastatic renal cell carcinoma |
| - | Trial, | RCC, | NA |
| 8127- | LF, | Phase I trial of oral talactoferrin alfa in refractory solid tumors |
| - | Trial, | Var, | NA |
| 8129- | LF, | Study on the Therapeutic Benefit on Lactoferrin in Patients with Colorectal Cancer Receiving Chemotherapy |
| - | Trial, | CRC, | NA |
| 8142- | LF, | A Randomized, Double-Blind, Controlled Trial to Assess the Effects of Lactoferrin at Two Doses vs. Active Control on Immunological and Safety Parameters in Healthy Adults |
| - | Trial, | Nor, | NA |
| 8138- | LF, | A review of the safety evidence on recombinant human lactoferrin for use as a food ingredient |
| - | Review, | Nor, | NA |
| 8203- | LGE, | Eug, | Citral and eugenol modulate DNA damage and pro-inflammatory mediator genes in murine peritoneal macrophages |
| - | in-vitro, | Nor, | NA |
| 8292- | lign, | Anticancer potential of flaxseed lignans, their metabolites and synthetic counterparts in relation with molecular targets: current challenges and future perspectives |
| - | Review, | Var, | NA |
| 8327- | LIN, | Recent updates on bioactive properties of linalool |
| - | Review, | Var, | NA |
| 8323- | LIN, | doxoR, | Efficacy of Combination Therapy with Linalool and Doxorubicin Encapsulated by Liposomes as a Two-in-One Hybrid Carrier System for Epithelial Ovarian Carcinoma |
| - | vitro+vivo, | Ovarian, | NA |
| 6479- | LIN, | Anticancer effect of linalool via cancer-specific hydroxyl radical generation in human colon cancer |
| - | in-vivo, | Colon, | HCT116 |
| 8377- | LT, | Luteolin: exploring its therapeutic potential and molecular mechanisms in pulmonary diseases |
| - | Review, | Asthma, | NA |
| 8398- | LT, | Luteolin: Nature's promising warrior against Alzheimer's and Parkinson's disease |
| - | Review, | AD, | NA | - | Review, | Park, | NA |
| 8397- | LT, | Effects and Mechanisms of Luteolin, a Plant-Based Flavonoid, in the Prevention of Cancers via Modulation of Inflammation and Cell Signaling Molecules |
| - | Review, | Var, | NA |
| - | in-vitro, | Nor, | MCF10 | - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | BC, | MDA-MB-468 | - | in-vitro, | PC, | Bxpc-3 |
| 2914- | LT, | Therapeutic Potential of Luteolin on Cancer |
| - | Review, | Var, | NA |
| 3268- | Lyco, | Lycopene as a Natural Antioxidant Used to Prevent Human Health Disorders |
| - | Review, | AD, | NA |
| 1710- | Lyco, | Lycopene: A Natural Arsenal in the War against Oxidative Stress and Cardiovascular Diseases |
| - | Review, | CardioV, | NA |
| 8520- | MAG, | The natural compound magnolol inhibits invasion and exhibits potential in human breast cancer therapy |
| - | in-vitro, | BC, | MDA-MB-231 |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:1025 State#:% Dir#:%
wNotes=0 sortOrder:rid,rpid