antiOx Cancer Research Results

antiOx, anti-oxidant activities: Click to Expand ⟱
Source:
Type:
Various antioxidants such as Nrf2, SODs, catalase, GPxs, PRDXs, and GSTs are altered in different cancers and have been linked to prognosis. Their overexpression can correlate with aggressive tumor behavior and resistance to treatment in many contexts.
Scientific Papers found: Click to Expand⟱
7374- HOO,    Exploring Ozonated Vegetable Oils as Antimicrobial and Functional Agents in Food Systems: A Systematic Narrative Review
- Review, Nor, NA
*AntiBio↑, *eff↝, *Half-Life↝, *eff↑, *Phen↑, *antiOx↑, eff↝, eff↝,
7371- HOO,    Phytochemical characterization of peanut oil and its ozonized form to explore biological activities in vitro
Dose↝, AntiBio↑, antiOx↑, AntiCan↑, selectivity↑,
7528- HT,    Involvement of the PI3K/AKT Intracellular Signaling Pathway in the AntiCancer Activity of Hydroxytyrosol, a Polyphenol from Olea europaea, in Hematological Cells and Implication of HSP60 Levels in Its Anti-Inflammatory Activity
- NA, NA, Jurkat - NA, NA, HL-60 - NA, NA, RAW264.7
*antiOx↑, *Inflam↓, *AntiBio↑, *cardioP↑, AntiCan↑, TumCCA↑, PI3K↓, MAPK↑, ROS↑, Apoptosis↑, Casp9↑, Bcl-2↓, p‑P53↓,
7531- HT,  OLE,    Olive Components (Biophenols or Polyphenols) in Neurodegenerative Disease Models and Clinical Studies: A Systematic Review of Evidence and Translational Barriers
- Review, AD, NA
*Aβ↑, *cognitive↑, *antiOx↑, *Inflam↓, *neuroP↑,
4645- HT,    Hydroxytyrosol: Bioavailability, toxicity, and clinical applications
- Review, NA, NA
*antiOx↑, *Inflam↓, AntiTum↑, *BioAv↓, *Half-Life↓, *BioAv↝, *BioAv↓,
4634- HT,    Hydroxytyrosol in cancer research: recent and historical insights on discoveries and mechanisms of action
- Review, Var, NA
*antiOx↑, *Inflam↓, AntiCan↑, ChemoSen↑, chemoP↑,
4633- HT,    Unlocking the effective alliance of β-lapachone and hydroxytyrosol against triple-negative breast cancer cells
- in-vitro, BC, NA
AntiCan↑, CSCs↓, antiOx↑, NQO1↑, TumCCA↑, ER Stress↑, Apoptosis↑, UPR↑,
3801- Hup,    An update on huperzine A as a treatment for Alzheimer's disease
- Review, AD, NA
*AChE↓, *antiOx↑, *neuroP↑,
3799- Hup,    The use of Huperzia species for the treatment of Alzheimer's disease
- NA, AD, NA
*antiOx↑, *Inflam↓, *AChE↓,
7565- HYP,    Potential Implications of Hyperoside on Oxidative Stress-Induced Human Diseases: A Comprehensive Review
- Review, AD, NA
*Inflam↓, *antiOx↑, *neuroP↑, *lipid-P↓, *ROS↓, *IL1β↓, *IL6↓, *IL8↓, *TNF-α↓, *MDA↓, *BAX↓, *Casp3↓, *Catalase↑, *SOD↑, *GSH↑, *BDNF↑, *TrkB↑, *NGF↑, *BDNF↑, *NF-kB↓, *AChE↓, *H2S↑, Casp3↑, Apoptosis↑, NF-kB↓, AMPK↑, HO-1↑, MAPK↑, cl‑Casp3↑, cl‑Casp9↑, BAX↑, SOD?, Catalase↓, NRF2↓, NQO1↓, HO-1↓, Bcl-2↓, TumCCA↑, FOXO1↑, TumAuto↑, Akt↓, mTOR↓, P70S6K↓, BMP7/OP1↓, *cardioP↑, *hepatoP↑, *antiCG↑, *AntiThr↑, *Diar↓, *AntiFungal↑, *CYP2D6↓, *PDGFR-BB↓, *PDGFRB↓, *toxicity↓, *Half-Life↑,
7564- HYP,    Pharmacological activities and therapeutic potential of Hyperoside in the treatment of Alzheimer's and Parkinson's diseases: A systemic review
- Review, AD, NA - Review, Park, NA
*antiOx↑, *Inflam↓, *Apoptosis↓, *Aβ↓, *AChE↓,
7563- HYP,    Hyperoside alleviates macrophages and microglia-mediated neuroinflammation and oxidative stress through activating PI3K/AKT and Nrf2/HO-1 signaling pathway post spinal cord injury
- vitro+vivo, Nor, NA
*Inflam↓, *antiOx↑, *Dose↝, *IL1β↓, *IL6↓, *TNF-α↓, *iNOS↓, *COX2/PTGS2↓, *NOX4↓, *NOX2↓, *NOX1↓, *PI3K↑, *Akt↑, *NRF2↑, *HO-1↑, *neuroP↑,
7552- HYP,    Hyperoside exerts potent anticancer activity in skin cancer
- vitro+vivo, Melanoma, NA
AntiCan↑, *Inflam↓, *antiOx↑, PI3K↓, Akt↓, mTOR↓, TumCP↓, Apoptosis↑, TumAuto↑, chemoPv↑,
7584- I3C,    Functional effect of indole-3 carbinol in the viability and invasive properties of cultured cancer cells
- in-vitro, Cerv, HeLa - in-vitro, CRC, HCT8 - in-vitro, Liver, HepG2
TumCP↓, Apoptosis↑, TumCI↓, *antiOx↑, AhR↑, MMP↓, Casp3↑, Casp8↑,
7385- IBC,    Fighting cancer by triggering non-canonical mitochondrial permeability transition-driven necrosis through reactive oxygen species induction
- vitro+vivo, Lung, A549 - in-vitro, BC, 4T1
Apoptosis↑, necrosis↑, ROS↑, mtDam↑, Ca+2↑, MPT↑, MMP↓, AntiCan↑, *AntiBio↑, *Inflam↓, *antiOx↓, *neuroP↑, p‑Akt↓, DHODH↓, Diff↑, MAPK↑,
7801- IBC,    Isobavachalcone as an Active Membrane Perturbing Agent and Inhibitor of ABCB1 Multidrug Transporter
- in-vitro, CRC, HT-29
PSEN2/PS-2↓, AntiCan↑, Apoptosis↑, Akt↓, ERK↓, *antiOx↑, *Inflam↓, *neuroP↑, *toxicity↓, selectivity↑,
7672- iod,    Adjuvant Effect of Molecular Iodine in Conventional Chemotherapy for Breast Cancer. Randomized Pilot Study
- Trial, BC, NA
Dose↝, OS↑, TumCI↓, Apoptosis↑, EstroRS/ERS↑, eff↑, *cardioP↑, *antiOx↑, *Inflam↓,
7674- iod,    Molecular iodine induces caspase-independent apoptosis in human breast carcinoma cells involving the mitochondria-mediated pathway
- in-vitro, BC, NA
AntiTum↑, selectivity↑, MMP↓, antiOx↑, Thiols↓, Bcl-2↓, BAX↑, eff↓, Casp↑, ROS↓, ROS↑, Cyt‑c↑, AIF↑,
7680- iod,  doxoR,    Iodine and doxorubicin, a good combination for mammary cancer treatment: antineoplastic adjuvancy, chemoresistance inhibition, and cardioprotection
- vitro+vivo, BC, NA
antiNeop↑, antiOx↑, Dose↝, TumVol↓, PCNA↓, Weight↑, cardioP↑, ChemoSen↑,
7682- iod,    Molecular Iodine Induces Anti- and Pro-Neoplastic Effects in Prostate Cancer Models
- in-vitro, Pca, LNCaP - in-vitro, Pca, DU145 - in-vitro, Pca, PC3
PPARγ↑, antiNeop↑, TumCD↑, TumCI↓, AntiCan⇅, antiOx↑, Inflam↓, Apoptosis↑, tumCV↓,
7722- IP6,    Cancer inhibition by inositol hexaphosphate (IP6) and inositol: from laboratory to clinic
- Review, Var, NA
eff↑, TumCP↓, Diff↑, TumCCA↑, Imm↑, antiOx↑, BioAv↑, toxicity↓, ChemoSen↑, TumMeta↓, QoL↑,
7640- IP6,  Ins,    Effects of Inositol Hexaphosphate and Myo-Inositol Administration in Breast Cancer Patients during Adjuvant Chemotherapy
- Trial, BC, NA
*antiOx↑, QoL↑, RBC↑, HemoG↑, WBC↑, chemoP↑, Dose↝,
7646- IP6,  Ins,    Protection against cancer by dietary IP6 and inositol
- Review, Var, NA
*antiOx↑, TumCG↓, TumMeta↓, Imm↑, kidSt↓, LDL↓, TumCCA↑, TumCP↓, Diff↑, ChemoSen↑, QoL↑,
7690- IP6,  Ins,    Inositol Hexaphosphate (IP6) and Colon Cancer: From Concepts and First Experiments to Clinical Application
- Review, Colon, NA
AntiCan↑, Imm↑, antiOx↑, TumCP↓, Diff↑, TumCG↓, eff↑, P21↓, p27/CDKN1B↓, pRB↓, TumCCA↑, PI3K↓, Akt↓, PKCδ↓, RAS↓, ERK↓, NF-kB↓, Inflam↓, MMP9↓, IronCh↑, NK cell↑, selectivity↑, ChemoSen↑, chemoP↑, toxicity↓, Remission↑,
7763- ISL,    Harnessing Liquiritigenin: A Flavonoid-Based Approach for the Prevention and Treatment of Cancer
AntiCan↑, *antiOx↓, *Inflam↓, TumCP↓, Apoptosis↑, NF-kB↓, PI3K↓, Akt↓, mTOR↓, *AntiArt↑, Casp8↑, Cyt‑c↑, Casp↑, cl‑PARP↑, GutMicro↑, BioAv↑, BioAv↓, Half-Life↓,
7747- ISL,    Isoliquiritigenin Induces Apoptosis via ROS-Mediated Inhibition of p38/mTOR/STAT3 Pathway in Human Melanoma Cells
- in-vitro, Melanoma, SK-MEL-28
*Inflam↓, *AntiViral↑, *AntiTum↑, *antiOx↑, cl‑Casp9↑, cl‑Casp7↑, cl‑Casp3↑, cl‑PARP↑, BAX↑, Bcl-2↓, Cyt‑c↑, cycD1/CCND1↓, cycD1/CCND1↓, survivin↓, ROS↓, eff↓, p‑mTOR↓, p‑STAT3↓, p‑MAPK↓,
7758- ISL,    Targeting the JAK/STAT pathway with isoliquiritigenin in ovarian cancer: molecular mechanisms and therapeutic implications
- Review, Ovarian, NA
JAK↓, STAT↓, toxicity↓, *antiOx↑, *ROS↓, *NRF2↑, *ARE↑, *HO-1↑, *NQO1↑, *Inflam↓, *NF-kB↓, *MAPK↓, *SOD↑, *Catalase↑, *GPx↑, *AntiViral↑, *NADPH↑, ROS↓, p38↓, mTOR↓, STAT3↓, cycD1/CCND1↓, survivin↓, p38↑, MAPK↑, mtDam↑, ER Stress↑, ROS↑, Apoptosis↑, GLUT4↓, ATP↓, Glycolysis↓, eff↑,
7782- ISL,  BUT,  SCP,    Butein, isoliquiritigenin, and scopoletin attenuate neurodegeneration via antioxidant enzymes and SIRT1/ADAM10 signaling pathway
- in-vitro, AD, SH-SY5Y
*Inflam↓, *AntiBio↑, *antiOx↑, *Apoptosis↓, *ROS↓, *SIRT1↑, *FOXO3↑, *ADAM10↑, *Bcl-2↝, *Catalase↑, *SOD2↑, *neuroP↑, *GSR↑, *GPx↑, *GSH↑,
7765- ISL,    Isoliquiritigenin as a modulator of the Nrf2 signaling pathway: potential therapeutic implications
- Review, Var, NA
*antiOx↑, *AntiCan↑, *AntiTum↑, *AntiDiabetic↑, *cardioP↑, *RenoP↑, *NRF2↑, *NQO1↝, *HO-1↑, *SOD↑, *toxicity↓, *BioAv↓, *Half-Life↓, *BBB↑, *neuroP↑, *Stroke↓, *GSK‐3β↓, *p‑GSK‐3β↑, *hepatoP↑, *Inflam↓, *ROS↓, *MPO↓, *MDA↓,
7778- ISL,    Isoliquiritigenin, a potent human monoamine oxidase inhibitor, modulates dopamine D1, D3, and vasopressin V1A receptors
- Study, Park, NA - Study, AD, NA
*neuroP?, TumCP↓, *Inflam↓, *hepatoP↑, angioG↓, *AntiBio↑, *AntiDiabetic↓, *ROS↓, *antiOx↑, *MAOA↓, *MAOB↓,
7737- isoFl,    An updated review of dietary isoflavones: Nutrition, processing, bioavailability and impacts on human health
- Review, Nor, NA
*cardioP↑, Risk↓, *BMD↑, *eff↑, *antiOx↑, *lipid-P↓, *LDL↓, AntiThr↑, AntiAg↑, PSA↓, TumCCA↑, cognitive↑, memory↑,
7735- isoFl,    Soy Isoflavones in Integrative Oncology: Increased Efficacy and Decreased Toxicity of Cancer Therapy
- Review, Var, NA
Risk↓, ChemoSen↑, chemoP↑, RadioS↑, radioP↑, NF-kB↓, DNMTs↓, TumMeta↓, angioG↓, antiOx↑, BioAv↑, toxicity↓,
7800- ISQ,    Isoquercitrin Attenuates Oxidative Liver Damage Through AMPK-YAP Signaling: An Integrative In Silico, In Vitro, and In Vivo Study
- vitro+vivo, Nor, HepG2
*antiOx↑, *Inflam↓, *AntiCan↑, *ROS↓, *MMP↑, *STK11/LKB1↑, *AMPK↑, *p‑AMPK↑, *ACC↑, *ALAT↓, *AST↓, *hepatoP↑,
7848- ISQ,    Review of anticancer mechanisms of isoquercitin
- Review, Var, NA
BioAv↑, eff↑, *antiOx↓, TumCP↓, *Inflam↓, *AntiDiabetic↑, lipid-P↓, *toxicity↓, *Half-Life↝, *Half-Life↑, *XO↝, *IronCh↝, *VitC↑, *ROS↓, β-catenin/ZEB1↓, Casp3↑, Casp8↑, Casp9↑, MMP↓, p‑ERK↓, p‑cJun↑,
7845- ISQ,    Isoquercitrin, ingredients in Tetrastigma hemsleyanum Diels et Gilg, inhibits hepatocyte growth factor/scatter factor-induced tumor cell migration and invasion
- vitro+vivo, Bladder, NBT-II
p‑MET↓, TumCMig↓, TumCI↓, EMT↓, *Inflam?, *antiOx↑, *ROS↓, *lipid-P↓, *neuroP↑,
5119- JG,    Juglone Suppresses Inflammation and Oxidative Stress in Colitis Mice
- in-vivo, Nor, NA
*antiOx↑, *OS↑, *IL6↓, *IL12↓, *IL23↓, *TNF-α↓, *Inflam↓, *NF-kB↓, *NFE2L2↓, *ROS↓,
5113- JG,    Juglone in Oxidative Stress and Cell Signaling
- Review, Var, NA - Review, AD, NA
ROS↑, Pin1↓, antiOx⇅, *ROS↓, SMAD2↓, GSH↓, lipid-P↑, TumCCA↓, BAX↑, Bcl-2↓, Casp3↑, Casp9↑, Ca+2↑, Cyt‑c↑, AntiFungal↑, Bacteria↓, Akt↓,
7827- KaempF,  MBS,    Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
- Review, AD, NA
*neuroP↑, *Learn↑, *memory↑, *antiOx↑, *Inflam↓, *Aβ↓, *cognitive↑, *BDNF↑, *TrkB↑, *CREB↑, *ERβ/ESR2↑, *ERK↑, *ROS↓, *AChE↓, *Dose↑,
1791- LEC,    Vegetable lecithins: A review of their compositional diversity, impact on lipid metabolism and potential in cardiometabolic disease prevention
- Review, Nor, NA
*BioEnh↑, *antiOx↑, *BioEnh↑, *LDL↓, *HDL∅, *Obesity↓, eff↑, GutMicro↝,
1793- LEC,    Unmasking Sunflower Lecithin: Does Science Support the Claims?
- Review, NA, NA
BioEnh↑, memory↑, Inflam↓, GutMicro↑, antiOx↑,
1796- LEC,    A comprehensive review on pleiotropic effects and therapeutic potential of soy lecithin
- Review, NA, NA
BioAv↑, antiOx↑, LDL↓, memory↑,
7825- LT,  MBS,    Neuroprotective Potential of Mung Bean (Vigna radiata L.) Polyphenols in Alzheimer's Disease: A Review
- Review, AD, NA
*neuroP↑, *OS↑, *antiOx↑, *Aβ42↓, *AChE↓, *Aβ↓, *IRes↓, *p‑tau↓, *ROS↓, *Apoptosis↓, *Inflam↓, *Iron↝,
4294- LT,    Luteolin reduces zinc-induced tau phosphorylation at Ser262/356 in an ROS-dependent manner in SH-SY5Y cells
- in-vitro, NA, SH-SY5Y
*tau↓, *antiOx↑,
4293- LT,    Regulatory Role of NF-κB on HDAC2 and Tau Hyperphosphorylation in Diabetic Encephalopathy and the Therapeutic Potential of Luteolin
- in-vivo, Diabetic, NA
*Inflam↓, *antiOx↑, *neuroP↑, *cognitive↑, *p‑mTOR↓, *p‑NF-kB↓, *HDAC2↓, *BDNF↑, *other↓, *p‑tau↓,
4292- LT,    Luteolin for neurodegenerative diseases: a review
- Review, AD, NA - Review, Park, NA - Review, MS, NA - Review, Stroke, NA
*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↝, *BBB↑, *TNF-α↓, *IL1β↓, *IL6↓, *IL8↓, *IL33↓, *NF-kB↓, *BACE/β-secretase↓, *ROS↓, *SOD↑, *HO-1↑, *NRF2↑, *Casp3↓, *Casp9↑, *Bax:Bcl2↓, *UPR↑, *GRP78/BiP↑, *Aβ↓, *GSK‐3β↓, *tau↓, *CREB↑, *ATP↑, *cognitive↑, *BloodF↑, *BDNF↑, *TrkB↑, *memory↑, *PPARγ↑, *eff↑,
2930- LT,    Luteolin confers renoprotection against ischemia–reperfusion injury via involving Nrf2 pathway and regulating miR320
- in-vitro, Nor, NA
*RenoP↑, *ROS↓, *antiOx↑, *NRF2↓,
2921- LT,    Luteolin as a potential hepatoprotective drug: Molecular mechanisms and treatment strategies
- Review, Nor, NA
*hepatoP↑, *AMPK↑, *SIRT1↑, *ROS↓, STAT3↓, TNF-α↓, NF-kB↓, *IL2↓, *IFN-γ↓, *GSH↑, *SREBP1/SREBF1↓, *ZO-1↑, *TLR4↓, BAX↑, Bcl-2↓, XIAP↓, Fas↑, Casp8↑, Beclin-1↑, *TXNIP↓, *Casp1↓, *IL1β↓, *IL18↓, *NLRP3↓, *MDA↓, *SOD↑, *NRF2↑, *ER Stress↓, *ALAT↓, *AST↓, *iNOS↓, *IL6↓, *HO-1↑, *NQO1↑, *PPARα↑, *ATF4↓, *CHOP/DDIT3↓, *Inflam↓, *antiOx↑, *GutMicro↑,
2906- LT,    Luteolin, a flavonoid with potentials for cancer prevention and therapy
- Review, Var, NA
*Inflam↓, AntiCan↑, antiOx⇅, Apoptosis↑, TumCP↓, TumMeta↓, angioG↓, PI3K↓, Akt↓, NF-kB↓, XIAP↓, P53↑, *ROS↓, *GSTA1↑, *GSR↑, *SOD↑, *Catalase↑, *other↓, ROS↑, Dose↝, chemoP↑, NF-kB↓, JNK↑, p27/CDKN1B↑, P21↑, DR5↑, Casp↑, Fas↑, BAX↑, MAPK↓, CDK2↓, IGF-1↓, PDGF↓, EGFR↓, PKCδ↓, TOP1↓, TOP2↓, Bcl-xL↓, FASN↓, VEGF↓, VEGFR2/KDR/Flk1↓, MMP9↓, Hif1a↓, FAK↓, MMP1↓, Twist↓, ERK↓, P450↓, CYP1A1↓, CYP1A2↓, TumCCA↑,
2907- LT,    Protective effect of luteolin against oxidative stress‑mediated cell injury via enhancing antioxidant systems
- in-vitro, Nor, NA
*ROS↓, *Casp9↓, *Casp3↓, *Bcl-2↑, *BAX↓, *GSH↑, *SOD↑, *Catalase↑, *GPx↑, *HO-1↑, *antiOx↑, *lipid-P↓, *p‑γH2AX↓, eff↑,
2914- LT,    Therapeutic Potential of Luteolin on Cancer
- Review, Var, NA
*antiOx↑, *IronCh↑, *toxicity↓, *BioAv↓, *BioAv↑, DNAdam↑, TumCP↓, DR5↑, P53↑, JNK↑, BAX↑, cl‑Casp3↑, cl‑Casp8↑, cl‑Casp9↑, cl‑PARP↑, survivin↓, cycD1/CCND1↓, CycB/CCNB1↓, CDC2↓, P21↑, angioG↓, MMP2↓, AEG1↓, VEGF↓, VEGFR2/KDR/Flk1↓, MMP9↓, CXCR4↓, PI3K↓, Akt↓, ERK↓, TumAuto↑, LC3B-II↑, EMT↓, E-cadherin↑, N-cadherin↓, Wnt↓, ROS↑, NICD↓, p‑GSK‐3β↓, iNOS↓, COX2/PTGS2↓, NRF2↑, Ca+2↑, ChemoSen↑, ChemoSen↓, IFN-γ↓, RadioS↑, MDM2↓, NOTCH1↓, AR↓, TIMP1↑, TIMP2↑, ER Stress↑, CDK2↓, Telomerase↓, p‑NF-kB↑, p‑cMyc↑, hTERT/TERT↓, RAS↓, YAP/TEAD↓, TAZ↓, NF-kB↓, NRF2↓, HO-1↓, MDR1↓,

Showing Research Papers: 501 to 550 of 868
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 868

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

AntiBio↑, 1,   BMP7/OP1↓, 1,   DHODH↓, 1,   kidSt↓, 1,   PSEN2/PS-2↓, 1,   RBC↑, 1,   WBC↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 10,   antiOx⇅, 2,   Catalase↓, 1,   CYP1A1↓, 1,   GSH↓, 1,   HO-1↓, 2,   HO-1↑, 1,   lipid-P↓, 1,   lipid-P↑, 1,   NQO1↓, 1,   NQO1↑, 1,   NRF2↓, 2,   NRF2↑, 1,   ROS↓, 3,   ROS↑, 7,   SOD?, 1,   Thiols↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↑, 1,   ATP↓, 1,   CDC2↓, 1,   MMP↓, 4,   MPT↑, 1,   mtDam↑, 2,   XIAP↓, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AMPK↑, 1,   p‑cMyc↑, 1,   FASN↓, 1,   Glycolysis↓, 1,   LDL↓, 2,   PPARγ↑, 1,  

Cell Death(tgid=5) ⓘ

AhR↑, 1,   Akt↓, 8,   p‑Akt↓, 1,   Apoptosis↑, 12,   BAX↑, 7,   Bcl-2↓, 6,   Bcl-xL↓, 1,   Casp↑, 3,   Casp3↑, 4,   cl‑Casp3↑, 3,   cl‑Casp7↑, 1,   Casp8↑, 4,   cl‑Casp8↑, 1,   Casp9↑, 3,   cl‑Casp9↑, 3,   Cyt‑c↑, 4,   DR5↑, 2,   Fas↑, 2,   hTERT/TERT↓, 1,   iNOS↓, 1,   JNK↑, 2,   MAPK↓, 1,   MAPK↑, 4,   p‑MAPK↓, 1,   MDM2↓, 1,   necrosis↑, 1,   NICD↓, 1,   p27/CDKN1B↓, 1,   p27/CDKN1B↑, 1,   p38↓, 1,   p38↑, 1,   survivin↓, 3,   Telomerase↓, 1,   TumCD↑, 1,   YAP/TEAD↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   p‑cJun↑, 1,   pRB↓, 1,   tumCV↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↑, 3,   UPR↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1↑, 1,   LC3B-II↑, 1,   TumAuto↑, 3,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 1,   DNMTs↓, 1,   P53↑, 2,   p‑P53↓, 1,   cl‑PARP↑, 3,   PCNA↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 2,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 4,   P21↓, 1,   P21↑, 2,   TumCCA↓, 1,   TumCCA↑, 8,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CSCs↓, 1,   Diff↑, 4,   EMT↓, 2,   ERK↓, 4,   p‑ERK↓, 1,   FOXO1↑, 1,   p‑GSK‐3β↓, 1,   IGF-1↓, 1,   mTOR↓, 4,   p‑mTOR↓, 1,   NOTCH1↓, 1,   P70S6K↓, 1,   PI3K↓, 6,   RAS↓, 2,   STAT↓, 1,   STAT3↓, 2,   p‑STAT3↓, 1,   TAZ↓, 1,   TOP1↓, 1,   TOP2↓, 1,   TumCG↓, 2,   Wnt↓, 1,  

Migration(tgid=13) ⓘ

AEG1↓, 1,   AntiAg↑, 1,   Ca+2↑, 3,   E-cadherin↑, 1,   FAK↓, 1,   p‑MET↓, 1,   MMP1↓, 1,   MMP2↓, 1,   MMP9↓, 3,   N-cadherin↓, 1,   PDGF↓, 1,   PKCδ↓, 2,   SMAD2↓, 1,   TIMP1↑, 1,   TIMP2↑, 1,   TumCI↓, 4,   TumCMig↓, 1,   TumCP↓, 10,   TumMeta↓, 4,   Twist↓, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 4,   EGFR↓, 1,   Hif1a↓, 1,   VEGF↓, 2,   VEGFR2/KDR/Flk1↓, 2,  

Barriers & Transport(tgid=15) ⓘ

GLUT4↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   CXCR4↓, 1,   IFN-γ↓, 1,   Imm↑, 3,   Inflam↓, 3,   JAK↓, 1,   NF-kB↓, 8,   p‑NF-kB↑, 1,   NK cell↑, 1,   PSA↓, 1,   TNF-α↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 1,   EstroRS/ERS↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 5,   BioEnh↑, 1,   ChemoSen↓, 1,   ChemoSen↑, 7,   CYP1A2↓, 1,   Dose↝, 5,   eff↓, 2,   eff↑, 7,   eff↝, 2,   Half-Life↓, 1,   MDR1↓, 1,   P450↓, 1,   RadioS↑, 2,   selectivity↑, 4,  

Clinical Biomarkers(tgid=22) ⓘ

AR↓, 1,   EGFR↓, 1,   EstroRS/ERS↑, 1,   GutMicro↑, 2,   GutMicro↝, 1,   HemoG↑, 1,   hTERT/TERT↓, 1,   PSA↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 10,   AntiCan⇅, 1,   antiNeop↑, 2,   AntiTum↑, 2,   cardioP↑, 1,   chemoP↑, 5,   chemoPv↑, 1,   cognitive↑, 1,   memory↑, 3,   OS↑, 1,   Pin1↓, 1,   QoL↑, 3,   radioP↑, 1,   Remission↑, 1,   Risk↓, 2,   toxicity↓, 4,   TumVol↓, 1,   Weight↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 1,   Bacteria↓, 1,  
Total Targets: 200

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiArt↑, 1,   AntiBio↑, 5,   antiCG↑, 1,   Aβ42↓, 1,   CYP2D6↓, 1,   IRes↓, 1,   Learn↑, 1,   NOX1↓, 1,   NOX2↓, 1,   Stroke↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 3,   antiOx↑, 35,   ARE↑, 1,   Catalase↑, 5,   GPx↑, 3,   GSH↑, 4,   GSR↑, 2,   GSTA1↑, 1,   HDL∅, 1,   HO-1↑, 6,   Iron↝, 1,   lipid-P↓, 4,   MDA↓, 3,   MPO↓, 1,   NFE2L2↓, 1,   NOX4↓, 1,   NQO1↑, 2,   NQO1↝, 1,   NRF2↓, 1,   NRF2↑, 5,   ROS↓, 17,   SOD↑, 7,   SOD2↑, 1,   VitC↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,   IronCh↝, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↑, 1,   MMP↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACC↑, 1,   ALAT↓, 2,   AMPK↑, 2,   p‑AMPK↑, 1,   CREB↑, 2,   H2S↑, 1,   LDL↓, 2,   NADPH↑, 1,   PPARα↑, 1,   PPARγ↑, 1,   SIRT1↑, 2,   SREBP1/SREBF1↓, 1,   STK11/LKB1↑, 1,  

Cell Death(tgid=5) ⓘ

Akt↑, 1,   Apoptosis↓, 3,   BAX↓, 2,   Bax:Bcl2↓, 1,   Bcl-2↑, 1,   Bcl-2↝, 1,   Casp1↓, 1,   Casp3↓, 3,   Casp9↓, 1,   Casp9↑, 1,   iNOS↓, 2,   MAPK↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   other↓, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   ER Stress↓, 1,   GRP78/BiP↑, 1,   UPR↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

p‑γH2AX↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ERK↑, 1,   FOXO3↑, 1,   GSK‐3β↓, 2,   p‑GSK‐3β↑, 1,   HDAC2↓, 1,   p‑mTOR↓, 1,   PDGFRB↓, 1,   PI3K↑, 1,  

Migration(tgid=13) ⓘ

TXNIP↓, 1,   ZO-1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

ATF4↓, 1,   PDGFR-BB↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   IFN-γ↓, 1,   IL12↓, 1,   IL18↓, 1,   IL1β↓, 4,   IL2↓, 1,   IL23↓, 1,   IL33↓, 1,   IL6↓, 5,   IL8↓, 2,   Inflam?, 1,   Inflam↓, 27,   NF-kB↓, 4,   p‑NF-kB↓, 1,   TLR4↓, 1,   TNF-α↓, 4,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 6,   ADAM10↑, 1,   BDNF↑, 5,   MAOA↓, 1,   NGF↑, 1,   tau↓, 2,   p‑tau↓, 2,   TrkB↑, 3,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 4,   Aβ↑, 1,   BACE/β-secretase↓, 1,   MAOB↓, 1,   NLRP3↓, 1,   XO↝, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ERβ/ESR2↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 4,   BioAv↑, 1,   BioAv↝, 2,   BioEnh↑, 2,   Dose↑, 1,   Dose↝, 1,   eff↑, 3,   eff↝, 1,   Half-Life↓, 2,   Half-Life↑, 2,   Half-Life↝, 2,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 2,   AST↓, 2,   BloodF↑, 1,   BMD↑, 1,   GutMicro↑, 1,   IL6↓, 5,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 2,   AntiDiabetic↓, 1,   AntiDiabetic↑, 2,   AntiTum↑, 2,   cardioP↑, 5,   cognitive↑, 4,   hepatoP↑, 5,   memory↑, 2,   neuroP?, 1,   neuroP↑, 13,   Obesity↓, 1,   OS↑, 2,   RenoP↑, 2,   toxicity↓, 5,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 1,   AntiViral↑, 2,   Diar↓, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Phen↑, 1,  
Total Targets: 149

Scientific Paper Hit Count for: antiOx, anti-oxidant activities
37 Lycopene
31 Curcumin
28 Thymoquinone
25 Resveratrol
25 Alpha-Lipoic-Acid
25 Hydrogen Gas
24 Selenium NanoParticles
24 Quercetin
20 Silymarin (Milk Thistle) silibinin
19 Rosmarinic acid
17 Ferulic acid
16 Astaxanthin
16 Chlorogenic acid
15 Silver-NanoParticles
15 EGCG (Epigallocatechin Gallate)
14 Eugenol
14 Honokiol
13 Berberine
13 Carvacrol
12 Baicalein
12 Propolis -bee glue
12 Fisetin
11 Allicin (mainly Garlic)
10 Coenzyme Q10
10 Vitamin C (Ascorbic Acid)
10 Luteolin
9 Crocetin
9 Dandelion Root
9 Magnetic Fields
9 Moringa oleifera
8 Melatonin
8 Selenium
8 chitosan
8 Sulforaphane (mainly Broccoli)
8 Emodin
8 Urolithin
7 Radiotherapy/Radiation
7 Apigenin (mainly Parsley)
7 α-Bisabolol / Chamomile oil
7 Cinnamon
7 Chemotherapy
7 Fucoidan
7 Ginger/6-Shogaol/Gingerol
7 Magnolol
6 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
6 Ashwagandha(Withaferin A)
6 Betulinic acid
6 Boron
6 Caffeic acid
6 Capsaicin
6 Chrysin
6 Cichoric acid / Chicoric acid
6 Hydroxycinnamic-acid
6 Ellagic acid
6 Ginkgo biloba
6 Isoliquiritigenin
6 Piperine
5 doxorubicin
5 Beta-Caryophyllene
5 Thymol-Thymus vulgaris
5 Carnosine
5 Centella asiatica / Gotu kola → asiaticoside
5 Vitamin E
5 Carvone
5 Ginkgo biloba-EGb 761
5 Hibiscus sabdariffa
5 HydroxyTyrosol
5 Pterostilbene
5 Selenite (Sodium)
4 Cisplatin
4 beta-carotene(VitA)
4 Bacopa monnieri
4 Caffeic Acid Phenethyl Ester (CAPE)
4 Date Fruit Extract
4 D-limonene
4 flavonoids
4 Shilajit/Fulvic Acid
4 Gallic acid
4 Garcinol
4 Hyperoside
4 iodine
4 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
4 Mung Bean Sprouts
4 Shikonin
3 Anthocyanins
3 Cynara scolymus/Globe Artichoke/Artichoke Extract
3 Ascorbyl Palmitate
3 Chyawanprash
3 Vitamin K2
3 Carica papaya leaf extract
3 Cucurbitacin
3 Dipyridamole
3 Geraniol
3 Inositol
3 isoquercitrin
3 Lecithin
3 Naringin
3 Nimbolide
3 Rutin
3 Salvia officinalis
3 Taurine
3 Ursolic acid
2 1,8-Cineole
2 5-fluorouracil
2 Anethole/trans-Anethole
2 Fennel Oil/Foeniculum vulgare
2 Aromatherapy
2 Vitamin B6,pyridoxine
2 Chocolate
2 Echinacea
2 Eurycomanone
2 Genistein (soy isoflavone)
2 Ginkgetin
2 High-Ozonide Oil
2 Huperzine A/Huperzia serrata
2 Isobavachalcone
2 isoflavones
2 Juglone
2 Methylene blue
2 Phenylbutyrate
2 Phenethyl isothiocyanate
2 Propyl gallate
2 Rauwolfia serpentina/Indian Snakeroot
2 α-Santalol/Sandalwood oil
2 Shankhpushpi
2 Vitamin B1/Thiamine
2 Vitamin B12
2 Folic Acid, Vit B9
2 Vitamin D3
1 Astragalus
1 Citric Acid
1 Ajoene (compound of Garlic)
1 alpha Linolenic acid
1 DTS(dibenzyl trisulphide) from Anamu
1 Artemisinin
1 Aloe anthraquinones
1 beta-glucans
1 Baicalin
1 Biochanin A
1 Cannabidiol
1 Boswellia (frankincense)
1 Bruteridin(bergamot juice)
1 Carnosic acid
1 Celastrol
1 Chlorophyllin
1 Choline
1 methotrexate
1 Copper and Cu NanoParticles
1 Deguelin
1 Dihydrocaffeic Acid
1 diet Fermented Foods
1 diet Methionine-Restricted Diet
1 Aspirin
1 eicosapentaenoic acid
1 Fenbendazole
1 Gamma-aminobutyric acid
1 Gambogic Acid
1 Germanium Organic/Ge-132 / propagermanium (organogermanium)
1 Ginkgolide B
1 Germacranolide sesquiterpene lactone
1 hydrogen sulfide
1 Helleborus niger extracts – Christmas Rose
1 Oleuropein
1 Indole-3-carbinol
1 Butein
1 Scopoletin
1 Kaempferol
1 Lutein
1 Methyl salicylate / Sweet Birch oil
1 Magnetic Field Rotating
1 Methylsulfonylmethane
1 N-Acetyl-Cysteine
1 nicotinamide adenine dinucleotide
1 Neem
1 Oleocanthal
1 Oregano
1 Phenolic Acids
1 Polyphenols
1 Phosphatidylserine
1 Psoralidin
1 Perilla
1 Gold NanoParticles
1 Sinapic acid
1 Sulfasalazine
1 Sesame seeds and Oil
1 Iron
1 Spermidine
1 Terpinen-4-ol / Tea Tree Oil
1 cetuximab
1 Ginseng
1 Aflavin-3,3′-digallate
1 Vanillic Acid
1 Dichloroacetate
1 probiotics
1 Zinc
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:%  prod#:%  Target#:1103  State#:%  Dir#:%
  wNotes=0  sortOrder:rid,rpid

 

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