| 8340- | LDN, | Naltrexone at low doses upregulates a unique gene expression not seen with normal doses: Implications for its use in cancer therapy |
| - | in-vitro, | CRC, | HCT116 |
| 8334- | LDN, | Low-dose naltrexone targets the opioid growth factor-opioid growth factor receptor pathway to inhibit cell proliferation: mechanistic evidence from a tissue culture model |
| - | in-vitro, | Ovarian, | NA |
| 8335- | LDN, | The opioid growth factor (OGF) and low dose naltrexone (LDN) suppress human ovarian cancer progression in mice |
| - | vitro+vivo, | Ovarian, | SKOV3 |
| 8336- | LDN, | Low-dose naltrexone suppresses ovarian cancer and exhibits enhanced inhibition in combination with cisplatin |
| - | in-vivo, | Ovarian, | NA |
| 8337- | LDN, | Low-dose naltrexone inhibits colorectal cancer progression and promotes apoptosis by increasing M1-type macrophages and activating the Bax/Bcl-2/caspase-3/PARP pathway |
| - | in-vitro, | CRC, | NA |
| 8338- | LDN, | Low-dose naltrexone plays antineoplastic role in cervical cancer progression through suppressing PI3K/AKT/mTOR pathway |
| - | vitro+vivo, | Cerv, | HeLa | - | in-vitro, | Cerv, | SiHa |
| 8339- | LDN, | Low-dose naltrexone inhibits the epithelial-mesenchymal transition of cervical cancer cells in vitro and effects indirectly on tumor-associated macrophages in vivo |
| - | in-vivo, | Cerv, | HeLa |
| - | in-vitro, | Oral, | NA |
| 8290- | LE, | Licoricidin, an Active Compound in the Hexane/Ethanol Extract of Glycyrrhiza uralensis, Inhibits Lung Metastasis of 4T1 Murine Mammary Carcinoma Cells |
| - | vitro+vivo, | Pca, | DU145 |
| 8236- | LE, | Licorice (Glycyrrhiza glabra L.)-Derived Phytochemicals Target Multiple Signaling Pathways to Confer Oncopreventive and Oncotherapeutic Effects |
| - | Review, | Var, | NA |
| 8240- | LE, | Licorice flavonoids nanoparticles prepared by liquid antisolvent re-crystallization exhibit higher oral bioavailability and antioxidant activity in rat |
| - | in-vivo, | Nor, | NA |
| 8262- | LE, | Phytochemical profiling, antimicrobial, cytotoxic and apoptotic effects of Glycyrrhiza glabra ethanolic extract |
| - | in-vitro, | Liver, | HepG2 |
| 8263- | LE, | Glycyrrhiza glabra L. suppress the proliferation of non-small cell lung cancer by inducing necrosis rather than apoptosis despite increasing bax level |
| - | in-vitro, | Lung, | A549 |
| 8264- | LE, | ISL, | Glycyrrhiza glabra L. Extracts with Potential Antiproliferative and Anti-Migration Activities Against Breast and Gynecological Cancer Cell Lines |
| - | in-vitro, | BC, | MCF7 | - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | Melanoma, | A2780S | - | in-vitro, | Cerv, | HeLa |
| 8265- | LE, | Glycyrrhizin ameliorates colorectal cancer progression by regulating NHEJ pathway through inhibiting HMGB1-induced DNA damage response |
| - | vitro+vivo, | CRC, | NA |
| 8266- | LE, | Glycyrrhizin binds to high-mobility group box 1 protein and inhibits its cytokine activities |
| - | Study, | Nor, | NA |
| 8267- | LE, | Glycyrrhizin Attenuates the Process of Epithelial-to-Mesenchymal Transition by Modulating HMGB1 Initiated Novel Signaling Pathway in Prostate Cancer Cells |
| - | in-vitro, | Pca, | DU145 |
| 8268- | LE, | Glycyrrhizin Attenuates Carcinogenesis by Inhibiting the Inflammatory Response in a Murine Model of Colorectal Cancer |
| - | vitro+vivo, | CRC, | NA |
| 8269- | LE, | Glycyrrhiza glabra-Enhanced Extract and Adriamycin Antiproliferative Effect on PC-3 Prostate Cancer Cells |
| - | in-vitro, | Pca, | PC3 |
| 8270- | LE, | Rad, | Comparative Study of the Effect of Licorice Muco-adhesive Film on Radiotherapy Induced Oral Mucositis, A Randomized Controlled Clinical Trial |
| - | Trial, | HNSCC, | NA |
| 8271- | LE, | Pharmacokinetic profile of glycyrrhizin in healthy volunteers by a new high-performance liquid chromatographic method |
| - | Human, | Nor, | NA |
| 8272- | LE, | Glycyrrhizin upregulates PTEN and suppresses oncogenic signaling in breast cancer |
| - | in-vitro, | BC, | NA |
| 8291- | LE, | Glycyrrhizic acid inhibits leukemia cell growth and migration via blocking AKT/mTOR/STAT3 signaling |
| - | vitro+vivo, | AML, | TF1 |
| 8274- | LE, | Research on the Antiaging Activity of Licorice Water Extract in Aging Mice via Antioxidation, Neuronal Protection, Gut Microbiota Restoration, and PI3K/AKT/mTOR Modulation |
| - | in-vivo, | Nor, | NA |
| 8289- | LE, | Cisplatin, | Effects of Glycyrrhizin in a Mouse Model of Lung Adenocarcinoma |
| - | vitro+vivo, | Lung, | NA |
| 8288- | LE, | 18 β-glycyrrhetinic acid exhibits potent antitumor effects against colorectal cancer via inhibition of cell proliferation and migration |
| - | vitro+vivo, | CRC, | NA |
| 8287- | LE, | New insights into the antioxidant and apoptotic potential of Glycyrrhiza glabra L. during hydrogen peroxide mediated oxidative stress: An in vitro and in silico evaluation |
| - | in-vitro, | Nor, | NA |
| 8286- | LE, | Rad, | Preventive Effect of Glycyrrhiza Glabra Extract on Oral Mucositis in Patients Under Head and Neck Radiotherapy: A Randomized Clinical Trial |
| - | Trial, | HNSCC, | NA |
| 8285- | LE, | Glycyrrhizin Suppresses the Growth of Human NSCLC Cell Line HCC827 by Downregulating HMGB1 Level |
| - | in-vivo, | Lung, | HCC827 |
| 8284- | LE, | Glycyrrhizic acid from licorice down-regulates inflammatory responses via blocking MAPK and PI3K/Akt-dependent NF-κB signalling pathways in TPA-induced skin inflammation |
| - | in-vivo, | Nor, | NA |
| 8283- | LE, | Efficacy of oral administration of licorice as an adjunct therapy on improving the symptoms of patients with Parkinson's disease, A randomized double blinded clinical trial |
| - | Trial, | Park, | NA |
| 8282- | LE, | Glycyrrhizic Acid Inhibits Proliferation of Gastric Cancer Cells by Inducing Cell Cycle Arrest and Apoptosis |
| - | in-vitro, | GC, | MGC803 | - | in-vitro, | GC, | BGC-823 | - | in-vitro, | GC, | SGC-7901 |
| 8281- | LE, | A Licorice Roots Extract Induces Apoptosis and Cell Cycle Arrest and Improves Metabolism via Regulating MiRNAs in Liver Cancer Cells |
| - | in-vitro, | Liver, | NA |
| 8273- | LE, | A Systematic Review of the Effect of Licorice on Head and Neck Chemotherapy- and Radiotherapy-Induced Mucositis |
| - | Review, | HNSCC, | NA |
| 8279- | LE, | 18β-Glycyrrhetinic Acid Has Anti-Cancer Effects via Inducing Apoptosis and G2/M Cell Cycle Arrest, and Inhibiting Migration of A549 Lung Cancer Cells |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | Lung, | H23 | - | in-vitro, | Lung, | H460 |
| 8278- | LE, | Glycyrrhiza glabra (Licorice): A Comprehensive Review on Its Phytochemistry, Biological Activities, Clinical Evidence and Toxicology |
| - | Review, | Var, | NA |
| 8277- | LE, | Oncopreventive and oncotherapeutic potential of licorice triterpenoid compound glycyrrhizin and its derivatives: Molecular insights |
| - | Review, | Var, | NA |
| 8276- | LE, | Cisplatin, | Glycyrrhizin enhances the antitumor activity of cisplatin in non‑small cell lung cancer cells by influencing DNA damage and apoptosis |
| - | in-vitro, | NSCLC, | NA |
| 1040- | LE, | Licorice extract inhibits growth of non-small cell lung cancer by down-regulating CDK4-Cyclin D1 complex and increasing CD8+ T cell infiltration |
| - | in-vivo, | Lung, | H1975 |
| 1266- | LE, | Glycyrrhizin suppresses epithelial-mesenchymal transition by inhibiting high-mobility group box1 via the TGF-β1/Smad2/3 pathway in lung epithelial cells |
| - | in-vitro, | Lung, | A549 | - | in-vitro, | Nor, | BEAS-2B |
| 1306- | LE, | Modulations of the Bcl-2/Bax family were involved in the chemopreventive effects of licorice root (Glycyrrhiza uralensis Fisch) in MCF-7 human breast cancer cell |
| - | in-vitro, | BC, | MCF7 |
| - | in-vitro, | BC, | MCF7 |
| 1787- | LE, | Licorice and cancer |
| - | Review, | Var, | NA |
| 2453- | LE, | The Promoting Role of HK II in Tumor Development and the Research Progress of Its Inhibitors |
| - | Review, | Var, | NA |
| 8181- | LEC, | CUR, | Soybean lecithin-stabilized oil-in-water (O/W) emulsions increase the stability and in vitro bioaccessibility of bioactive nutrients |
| - | in-vitro, | Nor, | NA |
| 3706- | LEC, | Lecithin for dementia and cognitive impairment |
| - | Review, | AD, | NA |
| 1789- | LEC, | Lecithin Supplements and Breast Cancer Risk |
| - | Analysis, | NA, | NA |
| 1790- | LEC, | DHA, | Dietary Crude Lecithin Increases Systemic Availability of Dietary Docosahexaenoic Acid with Combined Intake in Rats |
| - | in-vivo, | Nor, | NA |
| 1791- | LEC, | Vegetable lecithins: A review of their compositional diversity, impact on lipid metabolism and potential in cardiometabolic disease prevention |
| - | Review, | Nor, | NA |
| 1793- | LEC, | Unmasking Sunflower Lecithin: Does Science Support the Claims? |
| - | Review, | NA, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:% State#:% Dir#:%
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