| 8202- | LGE, | Application of microencapsulation technology to improve the stability of citral in rodent diets |
| - | in-vivo, | Nor, | NA |
| 8302- | lign, | The flaxseed lignan secoisolariciresinol diglucoside decreases local inflammation, suppresses NFκB signaling, and inhibits mammary tumor growth |
| - | vitro+vivo, | BC, | E0771 | - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | BC, | MCF7 |
| 8305- | lign, | FS, | Effects of dietary flaxseed lignan extract on symptoms of benign prostatic hyperplasia |
| - | Trial, | BPH, | NA |
| 8296- | lign, | Metabolism of secoisolariciresinol-diglycoside the dietary precursor to the intestinally derived lignan enterolactone in humans |
| - | Trial, | Nor, | NA |
| 8295- | lign, | Distribution, biosynthesis and therapeutic potential of lignans |
| - | Review, | Var, | NA |
| 8294- | lign, | Secoisolariciresinol diglucoside induces pyroptosis by activating caspase-1 to cleave GSDMD in colorectal cancer cells |
| - | vitro+vivo, | CRC, | LoVo | - | in-vitro, | CRC, | SW-620 | - | in-vitro, | NA, | SW480 | - | in-vitro, | CRC, | HT-29 | - | in-vitro, | CRC, | HCT116 |
| 8293- | lign, | FS, | Flaxseed and its lignans inhibit estradiol-induced growth, angiogenesis, and secretion of vascular endothelial growth factor in human breast cancer xenografts in vivo |
| - | in-vivo, | BC, | MCF7 |
| 8292- | lign, | Anticancer potential of flaxseed lignans, their metabolites and synthetic counterparts in relation with molecular targets: current challenges and future perspectives |
| - | Review, | Var, | NA |
| 8316- | lign, | Flaxseed lignan lowers blood cholesterol and decreases liver disease risk factors in moderately hypercholesterolemic men |
| - | Trial, | Nor, | NA |
| 8297- | lign, | Pharmacokinetics of enterolignans in healthy men and women consuming a single dose of secoisolariciresinol diglucoside |
| - | Trial, | Nor, | NA |
| 8314- | lign, | Reduction in Ki-67 in Benign Breast Tissue of High Risk Women with the Lignan Secoisolariciresinol Diglycoside (SDG) |
| - | Trial, | BC, | NA |
| 8298- | lign, | Inhibitory Effects of Enterolactone on Growth and Metastasis in Human Breast Cancer |
| - | in-vitro, | BC, | MDA-MB-231 |
| 8312- | lign, | Influence of Flaxseed Lignan Supplementation to Older Adults on Biochemical and Functional Outcome Measures of Inflammation |
| - | Trial, | Nor, | NA |
| 8311- | lign, | The Power of Lignans: Plant Compounds with Multifaceted Health-Promoting Effects |
| - | Review, | Nor, | NA |
| 8299- | lign, | Dietary flaxseed alters tumor biological markers in postmenopausal breast cancer |
| - | Trial, | BC, | NA |
| 8309- | lign, | Preventive effects of lignan extract from flax hulls on experimentally induced benign prostate hyperplasia |
| - | in-vivo, | BPH, | NA |
| 8301- | lign, | Lignans intake and enterolactone concentration and prognosis of breast cancer: a systematic review and meta-analysis |
| - | Review, | BC, | NA |
| 8333- | LIN, | Linalool preferentially induces robust apoptosis of a variety of leukemia cells via upregulating p53 and cyclin-dependent kinase inhibitors |
| - | in-vitro, | AML, | NA |
| 8326- | LIN, | Linalool in cancer pharmacology: pharmacokinetic limitations and preclinical cytotoxic evidence for translational development |
| - | Review, | Var, | NA |
| 8332- | LIN, | Linalool decreases HepG2 viability by inhibiting mitochondrial complexes I and II, increasing reactive oxygen species and decreasing ATP and GSH levels |
| - | in-vitro, | Liver, | HepG2 | - | in-vitro, | Colon, | Caco-2 | - | in-vitro, | NA, | NIH-3T3 | - | in-vitro, | BC, | MCF7 | - | in-vitro, | Nor, | HEK293 |
| 8331- | LIN, | Antitumorigenic potential of linalool is accompanied by modulation of oxidative stress: an in vivo study in sarcoma-180 solid tumor model |
| - | in-vivo, | sarcoma, | S180 |
| 8330- | LIN, | SIRT3-SOD2-ROS pathway is involved in linalool-induced glioma cell apoptotic death |
| - | in-vitro, | GBM, | U87MG |
| 8328- | LIN, | Linalool inhibits the growth of human T cell acute lymphoblastic leukemia cells with involvement of the MAPK signaling pathway |
| - | in-vitro, | AML, | NA |
| 8317- | LIN, | Linalool induces cell cycle arrest and apoptosis in HepG2 cells through oxidative stress generation and modulation of Ras/MAPK and Akt/mTOR pathways |
| - | in-vitro, | Liver, | HepG2 |
| 8318- | LIN, | Linalool Exhibits Cytotoxic Effects by Activating Antitumor Immunity |
| - | in-vitro, | BC, | T47D | - | NA, | CRC, | SW-620 | - | NA, | Liver, | HepG2 |
| - | in-vitro, | Oral, | OECM-1 | - | in-vitro, | Nor, | FR-2 |
| 8320- | LIN, | Ameliorative Effect of Linalool in Cisplatin-Induced Nephrotoxicity: The Role of HMGB1/TLR4/NF-κB and Nrf2/HO1 Pathways |
| - | in-vivo, | Nor, | NA |
| 8321- | LIN, | doxoR, | Linalool, a plant-derived monoterpene alcohol, reverses doxorubicin resistance in human breast adenocarcinoma cells |
| - | in-vitro, | BC, | MCF7 |
| 8322- | LIN, | doxoR, | Effect of linalool as a component of Humulus lupulus on doxorubicin-induced antitumor activity |
| - | vitro+vivo, | Var, | NA |
| 8323- | LIN, | doxoR, | Efficacy of Combination Therapy with Linalool and Doxorubicin Encapsulated by Liposomes as a Two-in-One Hybrid Carrier System for Epithelial Ovarian Carcinoma |
| - | vitro+vivo, | Ovarian, | NA |
| 8324- | LIN, | Linalool targets NR3C2 to inhibit NF-κB-mediated gastric cancer progression |
| - | vitro+vivo, | GC, | NA |
| 8325- | LIN, | Validating linalool as a potential drug for breast cancer treatment based on machine learning and molecular docking |
| - | in-vitro, | BC, | NA |
| 8327- | LIN, | Recent updates on bioactive properties of linalool |
| - | Review, | Var, | NA |
| 8329- | LIN, | Microglial-targeting induced by intranasal linalool during neurological protection postischemia |
| - | in-vivo, | Stroke, | NA | - | in-vivo, | AD, | NA |
| 6484- | LIN, | Linalool Inhibits MCF-7 Tumor Growth in a Xenograft Model by Apoptosis Induction and Immune Modulation |
| - | vitro+vivo, | BC, | MCF7 |
| 6464- | LIN, | 1,8-Cin, | Anti-cancer mechanisms of linalool and 1,8-cineole in non-small cell lung cancer A549 cells |
| - | in-vitro, | NSCLC, | A549 | - | in-vitro, | Nor, | WI38 |
| 6479- | LIN, | Anticancer effect of linalool via cancer-specific hydroxyl radical generation in human colon cancer |
| - | in-vivo, | Colon, | HCT116 |
| 6480- | LIN, | Linalool Induces Cell Cycle Arrest and Apoptosis in Leukemia Cells and Cervical Cancer Cells through CDKIs |
| - | in-vitro, | lymphoma, | U937 | - | in-vitro, | Var, | HeLa |
| 6481- | LIN, | Linalool inhibits 22Rv1 prostate cancer cell proliferation and induces apoptosis |
| - | in-vivo, | Pca, | 22Rv1 |
| 6482- | LIN, | Pharmacological and molecular insights into linalool-rich Coriandrum sativum essential oil: Anticonvulsant, analgesic, anti-inflammatory, and antioxidant potential in rodent models |
| - | Review, | Nor, | NA |
| 6483- | LIN, | Linalool-Incorporated Nanoparticles as a Novel Anticancer Agent for Epithelial Ovarian Carcinoma |
| - | in-vitro, | Ovarian, | A2780S |
| 7706- | lpi, | NIV, | Final, 10-Year Outcomes with Nivolumab plus Ipilimumab in Advanced Melanoma |
| - | Trial, | Melanoma, | NA |
| 8385- | LT, | Luteolin regulates pyroptosis of triple-negative breast cancer cells through AKT signaling |
| - | vitro+vivo, | BC, | MDA-MB-231 |
| 8386- | LT, | Luteolin induces apoptosis in Philadelphia chromosome-positive acute lymphoblastic leukemia cell by regulating the PI3K/AKT signaling pathway |
| - | in-vitro, | ALL, | SUP-B15 |
| 8377- | LT, | Luteolin: exploring its therapeutic potential and molecular mechanisms in pulmonary diseases |
| - | Review, | Asthma, | NA |
| 8384- | LT, | Current situation and research progress of luteolin in the treatment of gastrointestinal malignant tumors |
| - | Review, | GC, | NA |
| 8383- | LT, | Luteolin inhibits DNA methyltransferase 1 and alpha 6-integrin gene expression to suppress proliferation and stemness in breast cancer cells from patients of West African ancestry |
| - | in-vivo, | BC, | NA |
| 8382- | LT, | Luteolin as a dietary flavonoid for brain health: modulating neuroinflammation and cognitive decline in neurodegenerative disorders |
| - | Review, | AD, | NA | - | Review, | Park, | NA |
| 8397- | LT, | Effects and Mechanisms of Luteolin, a Plant-Based Flavonoid, in the Prevention of Cancers via Modulation of Inflammation and Cell Signaling Molecules |
| - | Review, | Var, | NA |
| 8380- | LT, | Luteolin, a bioactive compound from Celastrus orbiculatus stem, inhibits cervical cancer via CA2 suppression: A translational study bridging basic research and clinical application |
| - | Trial, | Cerv, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:% State#:% Dir#:%
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