| 3955- | Taur, | Mechanism of neuroprotective function of taurine |
| - | in-vitro, | NA, | NA |
| 3967- | Taur, | The Effects of Oral Taurine on Resting Blood Pressure in Humans: a Meta-Analysis |
| - | Review, | Nor, | NA |
| - | in-vivo, | AD, | NA |
| 3950- | Taur, | Taurine Supplementation as a Neuroprotective Strategy upon Brain Dysfunction in Metabolic Syndrome and Diabetes |
| - | Review, | Diabetic, | NA | - | Review, | Stroke, | NA | - | Review, | AD, | NA |
| 3951- | Taur, | Taurine Supplementation Alleviates Blood Pressure via Gut–Brain Communication in Spontaneously Hypertensive Rats |
| - | in-vivo, | NA, | NA |
| 3952- | Taur, | Taurine and Astrocytes: A Homeostatic and Neuroprotective Relationship |
| - | Review, | AD, | NA | - | Review, | Stroke, | NA |
| 3953- | Taur, | Role of taurine in regulation of intracellular calcium level and neuroprotective function in cultured neurons |
| - | in-vitro, | AD, | NA |
| 3956- | Taur, | Mechanisms underlying taurine protection against glutamate-induced neurotoxicity |
| - | Review, | AD, | NA |
| 3954- | Taur, | Mode of action of taurine as a neuroprotector |
| - | in-vitro, | AD, | NA |
| 1202- | Tb, | The influence of theobromine on angiogenic activity and proangiogenic cytokines production of human ovarian cancer cells |
| - | in-vitro, | Ovarian, | NA |
| 5327- | TFdiG, | Theaflavin-3, 3'-digallate induces apoptosis and G2 cell cycle arrest through the Akt/MDM2/p53 pathway in cisplatin-resistant ovarian cancer A2780/CP70 cells |
| - | in-vitro, | Ovarian, | A2780S |
| 5328- | TFdiG, | Study on mechanism of low bioavailability of black tea theaflavins by using Caco-2 cell monolayer |
| - | in-vitro, | NA, | Caco-2 |
| 5329- | TFdiG, | The Microbiota Is Essential for the Generation of Black Tea Theaflavins-Derived Metabolites |
| - | Human, | Nor, | NA |
| 5330- | TFdiG, | Cisplatin, | Theaflavin-3,3′-Digallate Enhances the Inhibitory Effect of Cisplatin by Regulating the Copper Transporter 1 and Glutathione in Human Ovarian Cancer Cells |
| - | in-vitro, | Ovarian, | A2780S | - | in-vitro, | Ovarian, | OVCAR-3 |
| 5331- | TFdiG, | Anti-Cancer Properties of Theaflavins |
| - | Review, | Var, | NA |
| 5332- | TFdiG, | Theaflavin-3,3′-digallate triggers apoptosis in osteosarcoma cells via the caspase pathway |
| - | vitro+vivo, | OS, | 143B | - | in-vitro, | OS, | U2OS |
| 5333- | TFdiG, | Theaflavin-3,3′-Digallate Plays a ROS-Mediated Dual Role in Ferroptosis and Apoptosis via the MAPK Pathway in Human Osteosarcoma Cell Lines and Xenografts |
| - | vitro+vivo, | OS, | MG63 |
| 5334- | TFdiG, | Theaflavin inhibits the malignant phenotype of human anaplastic thyroid cancer 8305C cells by regulating lipid metabolism via PI3K/AKT signaling |
| - | in-vitro, | Thyroid, | 8505C |
| 5335- | TFdiG, | Microbial Metabolism of Theaflavin-3,3′-digallate and Its Gut Microbiota Composition Modulatory Effects |
| - | in-vivo, | Nor, | NA |
| 5339- | TFdiG, | Pre-treated theaflavin-3,3′-digallate has a higher inhibitory effect on the HCT116 cell line |
| - | in-vitro, | CRC, | HCT116 |
| 5338- | TFdiG, | Isolation and antioxidant characterization of theaflavin for neuroprotective effect in mice model |
| - | in-vivo, | Nor, | NA |
| 5337- | TFdiG, | Theaflavin 3,3'-digallate suppresses metastasis and reduces insulin-like growth factor-1-induced cancer stemness and invasiveness in human melanoma cells |
| - | in-vitro, | Melanoma, | A375 | - | in-vitro, | Melanoma, | A2058 |
| 5336- | TFdiG, | Theaflavin-3,3′-Digallate Protects Cartilage from Degradation by Modulating Inflammation and Antioxidant Pathways |
| - | in-vivo, | Nor, | NA |
| 2373- | TMZ, | The role of pyruvate kinase M2 in anticancer therapeutic treatments |
| - | Review, | Var, | NA |
| 139- | Tomatine, | CUR, | Combination of α-Tomatine and Curcumin Inhibits Growth and Induces Apoptosis in Human Prostate Cancer Cells |
| - | in-vitro, | Pca, | PC3 |
| 113- | TQ, | Selective Targeting of the Hedgehog Signaling Pathway by PBM Nanoparticles in Docetaxel-Resistant Prostate Cancer |
| - | vitro+vivo, | Pca, | C4-2B |
| 962- | TQ, | Thymoquinone affects hypoxia-inducible factor-1α expression in pancreatic cancer cells via HSP90 and PI3K/AKT/mTOR pathways |
| - | in-vitro, | PC, | PANC1 | - | in-vitro, | Nor, | hTERT-HPNE | - | in-vitro, | PC, | AsPC-1 | - | in-vitro, | PC, | Bxpc-3 |
| 1138- | TQ, | Thymoquinone inhibits epithelial-mesenchymal transition in prostate cancer cells by negatively regulating the TGF-β/Smad2/3 signaling pathway |
| - | in-vitro, | Pca, | DU145 | - | in-vitro, | Pca, | PC3 |
| 1052- | TQ, | Thymoquinone Anticancer Effects Through the Upregulation of NRF2 and the Downregulation of PD-L1 in MDA-MB-231 Triple-Negative Breast Cancer Cells |
| - | in-vitro, | BC, | MDA-MB-231 |
| 1019- | TQ, | Thymoquinone suppresses migration of LoVo human colon cancer cells by reducing prostaglandin E2 induced COX-2 activation |
| - | vitro+vivo, | CRC, | LoVo |
| 2353- | TQ, | The effects of thymoquinone on pancreatic cancer: Evidence from preclinical studies |
| - | Review, | PC, | NA |
| 4565- | TQ, | Thymoquinone in the clinical treatment of cancer: Fact or fiction? |
| - | Review, | BC, | NA |
| 4538- | TQ, | Thymoquinone Anticancer Effects Through the Upregulation of NRF2 and the Downregulation of PD‐L1 in MDA‐MB‐231 Triple‐Negative Breast Cancer Cells |
| - | in-vitro, | BC, | MDA-MB-231 | - | in-vitro, | BC, | MDA-MB-468 |
| 5024- | TQ, | Thymoquinone: A Tie-Breaker in SARS-CoV2-Infected Cancer Patients? |
| - | Review, | Covid, | NA |
| 5221- | TQ, | Thymoquinone induces apoptosis through activation of caspase-8 and mitochondrial events in p53-null myeloblastic leukemia HL-60 cells |
| - | in-vitro, | AML, | HL-60 |
| 5222- | TQ, | Thymoquinone chemosensitizes colon cancer cells through inhibition of NF-κB |
| - | in-vitro, | CRC, | COLO205 | - | in-vitro, | CRC, | HCT116 |
| 1309- | TQ, | QC, | Thymoquinone and quercetin induce enhanced apoptosis in non-small cell lung cancer in combination through the Bax/Bcl2 cascade |
| - | in-vitro, | Lung, | NA |
| 1308- | TQ, | Thymoquinone induces apoptosis via targeting the Bax/BAD and Bcl-2 pathway in breast cancer cells |
| - | in-vitro, | BC, | MCF-7 |
| 2125- | TQ, | Thymoquinone Selectively Kills Hypoxic Renal Cancer Cells by Suppressing HIF-1α-Mediated Glycolysis |
| - | in-vitro, | RCC, | RCC4 | - | in-vitro, | RCC, | Caki-1 |
| 2112- | TQ, | Crude flavonoid extract of the medicinal herb Nigella sativa inhibits proliferation and induces apoptosis in breastcancer cells |
| - | in-vitro, | BC, | MCF-7 |
| 2124- | TQ, | Thymoquinone: an emerging natural drug with a wide range of medical applications |
| - | Review, | Var, | NA |
| 2123- | TQ, | Thymoquinone suppresses growth and induces apoptosis via generation of reactive oxygen species in primary effusion lymphoma |
| - | in-vitro, | lymphoma, | PEL |
| 2122- | TQ, | Review on Molecular and Therapeutic Potential of Thymoquinone in Cancer |
| - | Review, | Var, | NA |
| 2121- | TQ, | Thymoquinone Inhibits Tumor Growth and Induces Apoptosis in a Breast Cancer Xenograft Mouse Model: The Role of p38 MAPK and ROS |
| - | in-vitro, | BC, | MCF-7 | - | in-vitro, | BC, | MDA-MB-231 |
| 2120- | TQ, | Thymoquinone induces apoptosis of human epidermoid carcinoma A431 cells through ROS-mediated suppression of STAT3 |
| - | in-vitro, | Melanoma, | A431 |
| 2119- | TQ, | Dual properties of Nigella Sativa: anti-oxidant and pro-oxidant |
| - | Review, | Var, | NA |
| 2118- | TQ, | Rad, | In vivo radioprotective effects of Nigella sativa L oil and reduced glutathione against irradiation-induced oxidative injury and number of peripheral blood lymphocytes in rats |
| - | in-vivo, | Nor, | NA |
| 2117- | TQ, | Effects of Nigella sativa L. on Lipid Peroxidation and Reduced Glutathione Levels in Erythrocytes of Broiler Chickens |
| - | in-vivo, | Nor, | NA |
| 2116- | TQ, | Cisplatin, | Oral administration of Nigella sativa oil ameliorates the effect of cisplatin on membrane enzymes, carbohydrate metabolism and oxidative damage in rat liver |
| - | in-vivo, | Nor, | NA |
| 2115- | TQ, | Protective effects of Nigella sativa on gamma radiation-induced jejunal mucosal damage in rats |
| - | in-vivo, | Nor, | NA |
Query results interpretion may depend on "conditions" listed in the research papers. Such Conditions may include : -low or high Dose -format for product, such as nano of lipid formations -different cell line effects -synergies with other products -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:% prod#:% Target#:% State#:% Dir#:%
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